Integrated human practiceWe investigate 10 Chinese companies who provide ctDNA detection or cancer screening services. The investigation on current ctDNA detection services among 10 Chinese companies gives us a vision on the diversity of detection services and market share in China.
Conclusion:Each company has its unique method to carry out service. It suggests there is no technology monopoly in this industry. Therefore our product can compete with others in technology aspect as we have our own method to detect lung cancer. The time required to complete the service is between 2~8 days, except for EZlifeBio. It is seen to me that our product have a clear advantage in the length of time required because the detecting process can finish within few hours and the result can be read straight away. Similarly, EZlifeBio also sell detector and kit to customers and customers can run the detecting process. However, our target audiences are different. Their detectors are targeting hospitals or laboratories but our product is targeting the end user, patients, in this industry. The outcome from each service is slightly vary but all of them provide an assistance in cancer diagnosis or cure. It is distinct to our product as we aiming to provide a straightforward result for customer to understand. However, our product shows its limitation in the result compare to other outcomes from those services. It needs to be developed to generate more completed result in order to compete with other services.
Integrated human practice part IICommunication with BGI product research department Before we start to design our product, we consulted a staff who works in BGI product research department. She gave us a lot of advice on how to design a product and what should be the main concerns during the development of a product. Her suggestions inspired us to create a simple screening paper for lung cancer detection.
Peking University Shenzhen Hospital interview with Dr. Fang ZhengyuIt is our honor to discuss our project with Dr. Fang Zhengyu from Peking University Shenzhen Hospital. After we introduced and explained our project to him, he gave his opinions from a professional point of view. First, he questioned about the efficiency of using cell-free system to complete a series of reactions and the extremely low concentration of ctDNA in patient’s blood. Then, he also concerned about applying our design onto a screening chip instead of other product forms such as a detection kit. After that, we exchanged our opinions on those questions with Dr. Fang Zhengyu. It is greatl to have others opinion on our project. Dr. Fang’s suggestions helped us improve the design of our product and we decided to carry out further experiments to teat the efficiency of the screening paper.
AbstractAccording to our investigation above, there are already all kinds of ctDNA detecting services existed in the market. Therefore, it is hard to compete with those developed products. Our well designed paper chip has its own unique selling points which can open up a new small market. It is aiming to provide a fast and efficient method to detect ctDNA in individuals, leading to an early diagnosis of lung cancer or a monitor on cancer recurrence.
1. lung cancer in China
1.Trends in Incidence Rates (Age-Standardized to the Segi Standard Population) for Selected Cancers for Males: China, 2000 to 2011.Among the 10 most common cancers considered in the temporal trend analyses for men, lung cancer always has the highest incidence rate in China between 2000 and 2011, contributed almost 0.05% each year.
2.Trends in Incidence Rates (Age-Standardized to the Segi Standard Population) for Selected Cancers for Females: China, 2000 to 2011. For women, even though lung cancer has a lower incidence rate than that of men, it still has the second highest incidence rate in China.
3.Trends in Mortality Rates (Age-Standardized to the Segi Standard Population) for Selected Cancers for Males: China, 2000 to 2011.
4.Trends in Mortality Rates (Age-Standardized to the Segi Standard Population) for Selected Cancers for Females: China, 2000 to 2011.
5.Age-Standardized (Segi Standard Population) Incidence Rates for All Cancers Combined and Estimated New Cases (Thousands) for Selected Cancers in China, 2015, by Geographic Location (partial)
6.Age-Standardized (Segi Standard Population) Mortality Rates for All Cancers Combined and Estimated Deaths (Thousands) for Selected Cancers in China, 2015, by Geographic Location (partial)
2.Health check market in ChinaAccording to statistic data from ministry of public health, Chinese health market account for 373 million person-time in 2014. It had increased 62.17% compare to 230 million person-time in 2009. However, Chinese still has a relatively low percentage,27.27%, of people having health check each year as the population accounts for 1.368 billion people in China.
The number of people have health check each year from 2009 to 2014 (ten thousand)
the capacity of professional health check market from 2014 to 2020 (hundred billion yuan)
|Helpful to achieve objective||Harmful to achieve objectiv|
|Internal attributes of the organization||Strengths: - Our product has a simple procedure. Compare to the detecting services provided by companies, individuals can complete whole detecting process. -This product is cheaper than other similar products and services. -The criteria of detecting lung cancer is the ctDNA in patients’ blood. It can be found earlier than other symptoms of lung cancer, which gives an advantage in early cancer detection. -The result is clear and easy to understand.||Weakness: -At the moment, our product has it limitation on detecting a variety of cancer. This product only aim for EML4-ALK mutation in lung cancer. Only 4–6% of lung cancer involve this fusion gene.|
|External attributes of the organization||Opportunities: -According to the discussion on health check market above, China has a huge health check market with sustained growth annually. Our product is easy to used and efficient which is suitable to be used in health check. Unlike other lung cancer detection method, our screening chip provide detection services for a massive number of patients in a period of time. Therefore it has its advantage to be in the health check market. -People are more aware to have regular health check to prevent diseases. More people accept the concept of “early discover, early diagnosis, and early cure”. Therefore an additional option for lung cancer detection during health check match the demand from patients.||Threats: -Public may distrust our product due to lack of understanding of our product. Therefore education is necessary before promoting the product.|