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Revision as of 20:56, 10 September 2017

UFlorida

About Our Project


Tryptophol Synthesis for Mitigating Amphibian Chytridiomycosis


Amphibian populations worldwide are threatened by the disease Chytridiomycosis, which is caused by the aquatic fungal pathogen Batrachochytrium dendrobatidis (Bd). Chytridiomycosis often leads to death; however, a few species of amphibians are resistant to the Chytridiomycosis infection. The resistance is conferred by symbiotic bacteria present on their skin that produce antifungal metabolites. The UFlorida iGEM team seeks to develop a new treatment for Chytridiomycosis based on these antifungal metabolites. One such antifungal compound, tryptophol, has been shown to be effective at combating Bd at low doses. Tryptophan is converted to tryptophol by three enzymes, Aromatic Amino Acid Aminotransferase II, 2-oxo Acid Decarboxylase, and Alcohol Dehydrogenase I. Our team modified E.coli with the genes comprising the pathway for tryptophol synthesis. The UFlorida team expects to demonstrate that the tryptophol from the genetically modified E. coli will show antifungal activity against the Chytridiomycota family as an antifungal treatment for amphibians.


Our Values


MISSION: Our mission lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat.


VISION: Our vision Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat.

Portfolio


What we have created

Paris

Paris

Yes, we built Paris

New York

New York

We built New York

San Francisco

San Francisco

Yes, San Fran is ours


CONTACT

Contact us and we'll get back to you within 24 hours.

Chicago, US

+00 1515151515

myemail@something.com


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