Difference between revisions of "Team:TAS Taipei"
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<script> | <script> | ||
$(document).ready(function() { | $(document).ready(function() { | ||
| − | if(document.domain === " | + | if(document.domain === "2017.igem.org") |
setTimeout(function() { | setTimeout(function() { | ||
$("style:eq(0)").remove(); | $("style:eq(0)").remove(); | ||
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$DragOrientation: 3, //[Optional] Orientation to drag slide, 0 no drag, 1 horizental, 2 vertical, 3 either, default value is 1 (Note that the $DragOrientation should be the same as $PlayOrientation when $DisplayPieces is greater than 1, or parking position is not 0) | $DragOrientation: 3, //[Optional] Orientation to drag slide, 0 no drag, 1 horizental, 2 vertical, 3 either, default value is 1 (Note that the $DragOrientation should be the same as $PlayOrientation when $DisplayPieces is greater than 1, or parking position is not 0) | ||
| − | $BulletNavigatorOptions: { | + | $BulletNavigatorOptions: { //[Optional] Options to specify and enable navigator or not |
| − | $Class: $JssorBulletNavigator$, | + | $Class: $JssorBulletNavigator$, //[Required] Class to create navigator instance |
$ChanceToShow: 2, //[Required] 0 Never, 1 Mouse Over, 2 Always | $ChanceToShow: 2, //[Required] 0 Never, 1 Mouse Over, 2 Always | ||
$ActionMode: 1, //[Optional] 0 None, 1 act by click, 2 act by mouse hover, 3 both, default value is 1 | $ActionMode: 1, //[Optional] 0 None, 1 act by click, 2 act by mouse hover, 3 both, default value is 1 | ||
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<ul style='margin-left:0px'> | <ul style='margin-left:0px'> | ||
<li class="dropdown"> | <li class="dropdown"> | ||
| − | <a href="https:// | + | <a href="https://2017.igem.org/Team:TAS_Taipei/Background"><h4 class="dropdown-toggle disabled" data-toggle="dropdown"><b>PROJECT</b></h4></a> |
<div class="dropdown-menu"> | <div class="dropdown-menu"> | ||
<div class='subcategories_container'> | <div class='subcategories_container'> | ||
<div> | <div> | ||
| − | <h5><a href="https:// | + | <h5><a href="https://2017.igem.org/Team:TAS_Taipei/Background">Background</a></h5> |
</div> | </div> | ||
<div> | <div> | ||
| − | <h5><a href="https:// | + | <h5><a href="https://2017.igem.org/Team:TAS_Taipei/Achievements">Achievements</a></h5> |
</div> | </div> | ||
<div> | <div> | ||
| − | <h5><a href="https:// | + | <h5><a href="https://2017.igem.org/Team:TAS_Taipei/Collaborations">Collaborations</a></h5> |
</div> | </div> | ||
<div> | <div> | ||
| − | <h5><a href="https:// | + | <h5><a href="https://2017.igem.org/Team:TAS_Taipei/Parts">Parts</a></h5> |
</div> | </div> | ||
</div> | </div> | ||
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</li> | </li> | ||
<li class="dropdown"> | <li class="dropdown"> | ||
| − | <a href="https:// | + | <a href="https://2017.igem.org/Team:TAS_Taipei/Experimental_Summary"><h4 class='dropdown-toggle disabled' data-toggle="dropdown"><b>EXPERIMENTAL</b></h4></a> |
<div class="dropdown-menu"> | <div class="dropdown-menu"> | ||
<div class='subcategories_container'> | <div class='subcategories_container'> | ||
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</div> | </div> | ||
<div> | <div> | ||
| − | <h5><a href="https:// | + | <h5><a href="https://2017.igem.org/Team:TAS_Taipei/Notebook">Notebook</a></h5> |
</div> | </div> | ||
</div> | </div> | ||
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</li> | </li> | ||
<li class="dropdown"> | <li class="dropdown"> | ||
| − | <a href="https:// | + | <a href="https://2017.igem.org/Team:TAS_Taipei/Model"><h4 class='dropdown-toggle disabled' data-toggle="dropdown"><b>MODEL</b></h4></a> |
<div class="dropdown-menu"> | <div class="dropdown-menu"> | ||
<div class='subcategories_container'> | <div class='subcategories_container'> | ||
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</li> | </li> | ||
<li class="dropdown"> | <li class="dropdown"> | ||
| − | <a href="https:// | + | <a href="https://2017.igem.org/Team:TAS_Taipei/Human_Practices"><h4 class='dropdown-toggle disabled' data-toggle="dropdown"><b>HUMAN PRACTICE</b></h4></a> |
<div class="dropdown-menu"> | <div class="dropdown-menu"> | ||
<div class='subcategories_container'> | <div class='subcategories_container'> | ||
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</li> | </li> | ||
<li class="dropdown"> | <li class="dropdown"> | ||
| − | <a href="https:// | + | <a href="https://2017.igem.org/Team:TAS_Taipei/Safety"><h4 class='dropdown-toggle disabled' data-toggle="dropdown"><b>SAFETY</b></h4></a> |
<div class="dropdown-menu"> | <div class="dropdown-menu"> | ||
<div style='height:100px;'> | <div style='height:100px;'> | ||
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</li> | </li> | ||
<li class="dropdown"> | <li class="dropdown"> | ||
| − | <a href="https:// | + | <a href="https://2017.igem.org/Team:TAS_Taipei/Team"><h4 class='dropdown-toggle disabled' data-toggle="dropdown"><b>TEAM</b></h4></a> |
<div class="dropdown-menu"> | <div class="dropdown-menu"> | ||
<div class='subcategories_container'> | <div class='subcategories_container'> | ||
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<div class="row" style = "text-align:center;"> | <div class="row" style = "text-align:center;"> | ||
<div class="col-sm-2"> | <div class="col-sm-2"> | ||
| − | <a href="https:// | + | <a href="https://2017.igem.org/Team:TAS_Taipei" style='text-decoration: none'><img src="https://static.igem.org/mediawiki/2015/2/2f/Tas_igemlogo.png |
" alt="" style="width: 100px;"></a> | " alt="" style="width: 100px;"></a> | ||
</div> | </div> | ||
<div class="col-sm-8" style='text-align:center;'> | <div class="col-sm-8" style='text-align:center;'> | ||
| − | <a href="https:// | + | <a href="https://2017.igem.org/Team:TAS_Taipei" style='text-decoration: none;'> |
<h2 style="font-family:'Lato';letter-spacing:10px;color: white; font-size: 60px; margin-top: 0; margin-bottom: 0;"><b> | <h2 style="font-family:'Lato';letter-spacing:10px;color: white; font-size: 60px; margin-top: 0; margin-bottom: 0;"><b> | ||
| − | + | NANOTRAP</b></h2> | |
</a> | </a> | ||
</div> | </div> | ||
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<div u="caption" t="T" style="box-shadow: 0 0 10px 0;background-color:purple;padding:10px;position: absolute; top: 30px; left: 120px;border-style:solid;border-color:gold;border-width:10px"> | <div u="caption" t="T" style="box-shadow: 0 0 10px 0;background-color:purple;padding:10px;position: absolute; top: 30px; left: 120px;border-style:solid;border-color:gold;border-width:10px"> | ||
<p style = "color:white;font-size:30px;"> | <p style = "color:white;font-size:30px;"> | ||
| − | <b>TAS Taipei: | + | <b>TAS Taipei: 2017 iGEM Team</b> |
</p> | </p> | ||
<p style = "color:white;font-size:30px;"> | <p style = "color:white;font-size:30px;"> | ||
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</body> | </body> | ||
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Revision as of 06:22, 15 May 2017
ABSTRACT
Cataracts, the clouding of the lens, cause half of the world's blindness. Most cataracts are age-related and arise when crystallin proteins in the lens become oxidized and aggregate over time. Surgery is currently the only recognized treatment to effectively cure cataracts, but this method is expensive and invasive. Therefore, we formulated a natural and non-invasive alternative. In the eye, a natural antioxidant glutathione (GSH)—produced by the enzyme glutathione reductase (GSR)—exists to combat oxidation, but GSH levels decrease with age. Studies have also suggested that another enzyme—25-hydroxylase (CH25H)—can convert cholesterol in the eye into 25-hydroxycholesterol (25HC), which reverses crystallin aggregation. We expressed and purified GSR and CH25H for the prevention and treatment of cataracts, respectively. To deliver these proteins through the cornea and into the lens, we engineered biodegradable chitosan nanoparticles, thus creating a natural and non-invasive alternative to surgery.
