Difference between revisions of "Team:NU Kazakhstan"
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| + | <li><span><a href="index.html" style="color:#9ddef2;">Home</a></span></li> | ||
| + | <li><span><a href="research.html">Research</a></span></li> | ||
| + | <li><span><a href="https://2017.igem.org/Team:NU_Kazakhstan/Team">Team</a></span></li> | ||
| + | <li><span><a href="contact.html">Contact</a></span></li> | ||
| + | <li><span><a href="notebook.html">Notebook</a></span></li> | ||
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| − | < | + | <p>Pollution of natural resources with toxic metals is one of the biggest issues in a globe. Particularly hexavalent chromium is prevalent in an amount of exposed population, namely, it is 16 000 000 people all around the world. Moreover, it is quite problematic not only in industrial countries like Kazakhstan, which directly extracts and processes chromium ores (JSC "Aktobe Chromium Compounds Plant", JSC "Aksu ferroalloys Plant", LLC "Sunrise Chromium", JSC "Ferroalloy", TNS "Kazchromium", Aktobe Paint Factory, "Sunrise" Chromium Ores Processing Plant), but also in any places that are involved in electrical devices production; glass, stone, metal processing, tanned leather and textile production, dyes, resins, plastics, pharmaceuticals; aircraft. Cr (VI) may lead to a gastric ulcer, skin irritation, dermatitis; liver, kidneys & nervous system failure and even to cancer, since it generates reactive oxygen species and causes double strand breaks of human genetic material. At the present time, water pollution by chromates occupies one of the top places among global environmental problems. Control of the utilization of toxic wastes, namely chromates, with a wastewater, is currently at a very low level. The project considers the bioremediation as a solution to this problem. Bioremediation is a complex waste management technique that involves the use of modified biological organisms, in this case, microalgae to remove or neutralize pollutants from a contaminated site by converting hazardous substances into less toxic or non-toxic substances (toxic Cr (VI) to less toxic Cr (III). Thus, our team aims to genetically modify Chlamydomonas reinhardtii to gain the ability to:</p> |
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| − | + | Uptake the hexavalent chromium and to keep them inside.</li><li> | |
| − | + | Reduce toxic Cr (VI) to less toxic valence states.</li><li> | |
| − | < | + | To be killed in order to make sure that the system is safe for people and natural world.</li> |
| − | </ | + | <i>C.reinhardtii</i> is an autotrophic model organism that reproduces fast and does not require special control of growing temperature (15°C-35°C).</p><img src="File: Nukazmicroalgae.png"> |
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Revision as of 19:32, 29 June 2017
Pollution of natural resources with toxic metals is one of the biggest issues in a globe. Particularly hexavalent chromium is prevalent in an amount of exposed population, namely, it is 16 000 000 people all around the world. Moreover, it is quite problematic not only in industrial countries like Kazakhstan, which directly extracts and processes chromium ores (JSC "Aktobe Chromium Compounds Plant", JSC "Aksu ferroalloys Plant", LLC "Sunrise Chromium", JSC "Ferroalloy", TNS "Kazchromium", Aktobe Paint Factory, "Sunrise" Chromium Ores Processing Plant), but also in any places that are involved in electrical devices production; glass, stone, metal processing, tanned leather and textile production, dyes, resins, plastics, pharmaceuticals; aircraft. Cr (VI) may lead to a gastric ulcer, skin irritation, dermatitis; liver, kidneys & nervous system failure and even to cancer, since it generates reactive oxygen species and causes double strand breaks of human genetic material. At the present time, water pollution by chromates occupies one of the top places among global environmental problems. Control of the utilization of toxic wastes, namely chromates, with a wastewater, is currently at a very low level. The project considers the bioremediation as a solution to this problem. Bioremediation is a complex waste management technique that involves the use of modified biological organisms, in this case, microalgae to remove or neutralize pollutants from a contaminated site by converting hazardous substances into less toxic or non-toxic substances (toxic Cr (VI) to less toxic Cr (III). Thus, our team aims to genetically modify Chlamydomonas reinhardtii to gain the ability to:
- Uptake the hexavalent chromium and to keep them inside.
- Reduce toxic Cr (VI) to less toxic valence states.
- To be killed in order to make sure that the system is safe for people and natural world. C.reinhardtii is an autotrophic model organism that reproduces fast and does not require special control of growing temperature (15°C-35°C).
