Biosafety is the prevention of large-scale loss of biological integrity, focusing both on ecology and human health. These prevention mechanisms include conduction of regular reviews of the biosafety in laboratory settings, as well as strict guidelines to follow. Biosafety is used to protect us from harmful incidents. High security facilities are necessary when working with Synthetic Biology as there are possibilities of bioterrorism acts or release of harmful chemicals and or organisms into the environment. A complete understanding of experimental risks associated with synthetic biology is helping to enforce the knowledge and effectiveness of biosafety.

Scientist that favor the development of synthetic biology claim that the use of biosafety mechanisms such as suicide genes and nutrient dependencies will ensure the organisms cannot survive outside of the lab setting in which they were originally created. Kill switches were also actively developed to secure biosafety in synthetic biology.

After confirming developing the agr system of the Staphylococcus aureus , we contacted the Department of Infection of Southwest Hospital and the department of microbiology , consuling about the pathogenicity and biosafety level of Staphylococcus aureus. Doctor Li from the Department of Infection introduced us that the hospital acquired infection is always an unavoidable problem racent years; meawhile, professor Wang systematically introduced us the Staphylococcus aureus’ biosafety level and experimental operation of the standard process, all of which helped us during the later experiment.