Difference between revisions of "Team:NUS Singapore"

 
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<style>
 
<style>
 +
  
 
/************************************************** Image Carousel Section **************************************************/
 
/************************************************** Image Carousel Section **************************************************/
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     width: 100%;
 
     width: 100%;
 
     position: relative;
 
     position: relative;
−
 
 
}
 
}
 
/* Next & previous buttons */
 
/* Next & previous buttons */
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/* Caption text */
 
/* Caption text */
 
.text {
 
.text {
−
     color: #f2f2f2;
+
    font-family:"Snell Roundhand", cursive;
 +
     color:#ffffff;
 
     font-size: 15px;
 
     font-size: 15px;
 
     padding: 8px 12px;
 
     padding: 8px 12px;
 
     position: absolute;
 
     position: absolute;
−
     bottom: 8px;
+
     bottom: 80px;
 
     width: 100%;
 
     width: 100%;
−
     text-align: center;
+
     text-align: left;
 +
    font-size:30px;
 +
    font-weight:900;
 
}
 
}
  
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     animation-duration: 2s;
 
     animation-duration: 2s;
 
}
 
}
 +
 
@-webkit-keyframes fade {
 
@-webkit-keyframes fade {
 
   from {opacity: .4}  
 
   from {opacity: .4}  
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}
 
}
 
.column.larger_section {
 
.column.larger_section {
−
     width: 60%;  
+
     width: 70%;  
 
     float:left;
 
     float:left;
−
     padding-left:5%;
+
     padding-left:10%;
 
}
 
}
  
 
.column.larger_section p {  
 
.column.larger_section p {  
−
     width:90%;
+
    text-align:justify;
 +
}
 +
 
 +
.column.full_section {
 +
     width:100%;
 +
    position:relative;
 +
    padding-left:10%;
 +
    padding-right:10%;
 +
}
 +
 
 +
.column.full_section p {
 
     text-align:justify;
 
     text-align:justify;
 
}  
 
}  
  
 
.column.smaller_section {
 
.column.smaller_section {
−
     width: 40%;  
+
     width: 30%;  
 
     float:right;
 
     float:right;
 
     padding-right:5%;
 
     padding-right:5%;
 
}
 
}
  
−
.column.smaller_section p {  
+
.column.smaller_section img {  
−
     width:90%;
+
     margin-left:30%;
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     padding:5%;
+
     height:200px;
 
     text-align:justify;
 
     text-align:justify;
 
}
 
}
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   text-align: center;
 
   text-align: center;
 
   height:60px;
 
   height:60px;
−
   padding: 0px 0px;  /*height,width*/
+
   padding: 20px 0px;  /*height,width*/
 +
  font-family: arial;
 +
}
 +
 
 +
.gallery-intro-container p{
 +
  text-align:center;
 +
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 +
 
 +
.gallery-intro-container a{
 +
  text-align:center;
 +
  font-size:20px;
 
   font-family: arial;
 
   font-family: arial;
 +
  text-decoration:none;
 +
  color:#000000;
 +
  text-weight:bold;
 
}
 
}
  
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   text-decoration: none;
 
   text-decoration: none;
 
   color: white;
 
   color: white;
 +
}
 +
 +
/************************  Quick Link Footer  **************************/
 +
.quicklink p {
 +
background-color:#F0F3F4;
 +
width:100%;
 +
text-align: center;
 +
height:60px;
 +
padding:10px;
 +
margin:0px;
 +
font-weight: bold;
 +
font-size: 20px;
 +
}
 +
 +
.quicklink-container {
 +
      background-color:#F0F3F4;
 +
      width:100%;
 +
      height:200px;
 +
      position:absolute;
 +
}
 +
.quicklink-1 {
 +
background-color:#F0F3F4;
 +
width:25%;
 +
height:300px;
 +
padding-left:7%;
 +
padding-right:7%;
 +
position:relative;
 +
float:left;
 +
text-align: center;
 +
text-decoration: none;
 +
 +
}
 +
.quicklink-2 {
 +
background-color:#F0F3F4;
 +
width:25%;
 +
height:300px;
 +
padding-left:7%;
 +
padding-right:7%;
 +
position:relative;
 +
float:left;
 +
text-align: center;
 +
text-decoration: none;
 +
}
 +
.quicklink-3 {
 +
background-color:#F0F3F4;
 +
width:25%;
 +
height:300px;
 +
padding-left:7%;
 +
padding-right:7%;
 +
position:relative;
 +
float:left;
 +
text-align: center;
 +
text-decoration: none;
 +
}
 +
.quicklink-4 {
 +
background-color:#F0F3F4;
 +
width:25%;
 +
height:300px;
 +
padding-left:7%;
 +
padding-right:7%;
 +
position:relative;
 +
float:left;
 +
text-align: center;
 +
text-decoration: none;
 +
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 +
 +
.quicklink-4 a {
 +
        color:#808B96;
 +
          font-size:15px;
 +
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 +
.quicklink-3 a {
 +
        color:#808B96;
 +
font-size:15px;
 +
}
 +
.quicklink-2 a {
 +
        color:#808B96;
 +
font-size:15px;
 +
}
 +
.quicklink-1 a {
 +
        color:#808B96;
 +
font-size:15px;
 
}
 
}
  
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}
 
}
  
−
.footer-sponsor-container{
+
.footer-contact-container {
−
   width:70%; /*split the sponsor container from the full footer-container */
+
   width:100%;  
 +
  padding-left:40%;
 
   background-color:inherit;
 
   background-color:inherit;
−
  padding-top:20px;
 
 
   float:left;
 
   float:left;
−
}
+
   padding-top:none;
−
 
+
   border-top: 2px solid grey;
−
.footer-contact-container{
+
−
  width:30%; /*split the sponsor container from the full footer-container */
+
−
   padding-top:20px;
+
−
   background-color:inherit;
+
−
  float:right;
+
 
}
 
}
  
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     position:relative;
 
     position:relative;
 
     float:left;
 
     float:left;
 +
    width:5%;
 +
    height:auto;
 +
}
  
 +
.footer-sponsor-container{
 +
  width:100%;
 +
  background-color:inherit;
 +
  padding-left:8%;
 +
  padding-right:8%;
 
}
 
}
  
−
 
+
.footer-sponsor-container img{
 +
    width:140px;
 +
    height:80px;
 +
    margin-right:10px;
 +
}
 
/*********************  Responsive Design  *********************/
 
/*********************  Responsive Design  *********************/
  
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div.gallery-intro-container {
 
div.gallery-intro-container {
−
       height:30px;
+
       height:40px;
−
       padding: 0px 10px;  /*height,width*/
+
       padding: 10px 10px;  /*height,width*/
 
     }
 
     }
  
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   }  
 
   }  
 
   .column.smaller_section {
 
   .column.smaller_section {
−
       width: 100%;
+
       width: 20%;
 
       position: relative;
 
       position: relative;
 
       padding-left:15%;
 
       padding-left:15%;
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/*Sponsor and Social Contact Link Cover*/
 
/*Sponsor and Social Contact Link Cover*/
 +
.footer-sponsor-container img{
 +
    width:100px;
 +
    height:50px;
 +
    margin-right:5px;
 +
}
  
−
.social-icon img {
+
 
−
    width:25%;
+
.footer-sponsor-container{
−
    display:block;
+
  width:100%;
−
    padding:5px;
+
  background-color:inherit;
 +
  padding-left:5%;
 +
  padding-right:5%;
 +
}
 +
 
 +
.footer-container{
 +
  width:100%;
 +
  height:150px;
 +
  background-color:#F0F3F4 ;
 +
  position:absolute;
 +
}
 +
 
 +
img.social-icon {
 +
    margin:2%;
 
     position:relative;
 
     position:relative;
 
     float:left;
 
     float:left;
 +
    width:10%;
 +
    height:auto;
 
   }
 
   }
−
 
 
}
 
}
  
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<div id="slide">
 
<div id="slide">
 
   <div class="slideshow-container">
 
   <div class="slideshow-container">
−
     <div class="mySlides fade"> <img src="https://static.igem.org/mediawiki/2017/0/04/NUS_IGEM_Groupphoto_1_tailored.jpeg" > </div>
+
     <div class="mySlides fade"> <img src="https://static.igem.org/mediawiki/2017/0/0c/NUS_2017_IGEM_slideshow.png"> </div>
 
     <div class="mySlides fade"> <img src="https://static.igem.org/mediawiki/2017/d/d1/NUS_2017_IGEM_Group_Eng.jpeg"> </div>
 
     <div class="mySlides fade"> <img src="https://static.igem.org/mediawiki/2017/d/d1/NUS_2017_IGEM_Group_Eng.jpeg"> </div>
 
     <div class="mySlides fade"> <img src="https://static.igem.org/mediawiki/2017/0/04/NUS_IGEM_Groupphoto_1_tailored.jpeg"> </div>
 
     <div class="mySlides fade"> <img src="https://static.igem.org/mediawiki/2017/0/04/NUS_IGEM_Groupphoto_1_tailored.jpeg"> </div>
−
    <div class="mySlides fade"> <img src="https://static.igem.org/mediawiki/2017/d/d1/NUS_2017_IGEM_Group_Eng.jpeg"> </div>
 
 
     <a class="prev" onclick="plusSlides(-1)">&#10094;</a> <a class="next" onclick="plusSlides(1)">&#10095;</a>  
 
     <a class="prev" onclick="plusSlides(-1)">&#10094;</a> <a class="next" onclick="plusSlides(1)">&#10095;</a>  
 
   </div>
 
   </div>
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       <span class="dot" onclick="currentSlide(2)"></span>  
 
       <span class="dot" onclick="currentSlide(2)"></span>  
 
       <span class="dot" onclick="currentSlide(3)"></span>
 
       <span class="dot" onclick="currentSlide(3)"></span>
−
      <span class="dot" onclick="currentSlide(4)"></span>
 
 
   </div>
 
   </div>
 
  </div>   
 
  </div>   
  
 
<!--**************************************** Project Description with Image Section ****************************************-->
 
<!--**************************************** Project Description with Image Section ****************************************-->
−
<div style="position:center;">
+
   <h1>Making Engineering of Customised Kill Switches Easier</h1>  
−
   <h1>Project Description</h1>  
+
−
</div>
+
−
 
+
 
<div class="column larger_section">  
 
<div class="column larger_section">  
 
   <p>Many SynBio groups are engineering microbes that could one day be useful in detecting diseases, fighting cancer and monitoring heavy metals in rivers. However, engineered microbes may leak into the non-designated environment, posing threats to our natural ecosystem. This is a major hurdle towards the commercialization of engineered microbes. To address this, we need effective kill switches to prevent engineered microbes from escaping into the environment. However, existing kill switches have limitations and, more importantly, it is difficult to readily tailor make kill switches for different applications.</p><br>
 
   <p>Many SynBio groups are engineering microbes that could one day be useful in detecting diseases, fighting cancer and monitoring heavy metals in rivers. However, engineered microbes may leak into the non-designated environment, posing threats to our natural ecosystem. This is a major hurdle towards the commercialization of engineered microbes. To address this, we need effective kill switches to prevent engineered microbes from escaping into the environment. However, existing kill switches have limitations and, more importantly, it is difficult to readily tailor make kill switches for different applications.</p><br>
 
  <p>
 
  <p>
−
Team NUSgem aims to make engineering of customised, effective kill switches easier. To this end, we are developing a library of characterized sensors, a killing and verification module which can be used in a computer-aided design tool (such as Cello) and can be readily modelled. As a proof of concept, we focus on developing kill switch for engineered probiotics for human health.</p>
+
Currently, there is no harmonized framework for kill switch design and construction. Team NUSgem aims to make engineering of such customised, effective kill switches easier. To this end, we are developing a library of characterized sensors, a killing and verification module which can be used in computer-aided design and modelling tool (such as <a href ="http://www.cellocad.org/"> CELLO</a> and <a href="http://advancesyn.com/"> AdvanceSyn Studio </a>) and can be readily modelled. As a proof of concept, we will focus on developing a kill switch for engineered probiotics for human health.</p>  
−
</div>
+
  
−
<div class="column smaller_section">  
+
<p>
−
  <img src="https://static.igem.org/mediawiki/2017/9/90/NUS_IGEM_Lab_1.jpeg" alt="#" style="width:100%;height:300px;">
+
We are a team of 6 undergraduates and 1 recent graduate student from different disciplines including Biomedical Engineering, Electrical Engineering, Science and Economics.</p>
 
</div>
 
</div>
  
 +
<div class="column smaller_section">
 +
    <img src="https://static.igem.org/mediawiki/2017/3/31/NUS_2017_IGEM_badbacteria.png">
 +
    <img src="https://static.igem.org/mediawiki/2017/6/6b/NUS_2017_IGEM_goodbacteria.png">
 +
</div>
  
−
<!--********** Make seperation between two different sections **********-->
 
 
<div class="clear"></div>
 
<div class="clear"></div>
−
 
 
<!--**************************************** Video with Explanation Section ****************************************-->
 
<!--**************************************** Video with Explanation Section ****************************************-->
 
<div class="video_container">
 
<div class="video_container">
−
     <video controls>
+
     <video controls poster="https://static.igem.org/mediawiki/2017/9/91/NUS_2017_IGEM_outline_cover.png">
−
       <source src="https://static.igem.org/mediawiki/2017/8/8e/NUS_2017_IGEM_Video.mp4" type="video/mp4">
+
       <source src="https://static.igem.org/mediawiki/2017/6/6f/NUS_2017_IGEM_Videooverview.mp4" type="video/mp4">
 
     </video>
 
     </video>
 
</div>
 
</div>
  
−
<div class="clear"></div>
+
<!--********** Make seperation between two different sections **********-->
  
 
<!--**************************************** Homepage Gallery ****************************************-->
 
<!--**************************************** Homepage Gallery ****************************************-->
−
<div style="position:center;">
 
 
   <h1>Learn More</h1>
 
   <h1>Learn More</h1>
−
  <h2></h2>
+
<!--1st image_INTERLAB STUDY-->
−
</div>
+
−
 
+
−
<!--1st image_Interlab study-->
+
 
<div class="polaroid">   
 
<div class="polaroid">   
 
    
 
    
−
   <img src="https://static.igem.org/mediawiki/2017/9/90/NUS_IGEM_Lab_1.jpeg" alt="#" style="width:100%;display: block;height:180px">
+
   <img src="https://static.igem.org/mediawiki/2017/5/56/NUS_2017_IGEM_home_interlab.png" alt="#" style="width:100%;display: block;height:180px">
 
    
 
    
 
   <div class="gallery-intro-container">
 
   <div class="gallery-intro-container">
−
     <p>Interlab Study</p>
+
     <a href="https://2017.igem.org/Team:NUS_Singapore/InterLab">INTERLAB STUDY</a>
 
   </div>
 
   </div>
 
    
 
    
−
   <div class="gallery-overlay">
+
   <div class="gallery-overlay" style="background-color: #ffccbc">
 
     <div class="gallery-overlay-text"><a href="https://2017.igem.org/Team:NUS_Singapore/InterLab">Interlab Study</a></div>
 
     <div class="gallery-overlay-text"><a href="https://2017.igem.org/Team:NUS_Singapore/InterLab">Interlab Study</a></div>
 
   </div>
 
   </div>
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</div>
 
</div>
  
−
<!--2nd image_Modelling-->
+
<!--2nd image_MODELLING-->
 
<div class="polaroid">
 
<div class="polaroid">
 
    
 
    
−
   <img src="https://static.igem.org/mediawiki/2017/b/bb/NUS_IGEM_Lab_3.jpeg" alt="modelling" style="width:100%;display: block;height:180px">
+
   <img src="https://static.igem.org/mediawiki/2017/c/cc/NUS_2017_IGEM_home_modelling.png" alt="modelling" style="width:100%;display: block;height:180px">
 
    
 
    
 
   <div class="gallery-intro-container">
 
   <div class="gallery-intro-container">
−
     <p>Modelling</p>
+
     <a href="https://2017.igem.org/Team:NUS_Singapore/Model">MODELLING</a>
 
   </div>
 
   </div>
  
−
   <div class="gallery-overlay" style="background-color: #0CFA10">
+
   <div class="gallery-overlay" style="background-color: #b2dfdb">
 
     <div class="gallery-overlay-text"><a href="https://2017.igem.org/Team:NUS_Singapore/Model">Modelling</a></div>
 
     <div class="gallery-overlay-text"><a href="https://2017.igem.org/Team:NUS_Singapore/Model">Modelling</a></div>
 
   </div>
 
   </div>
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</div>
 
</div>
  
−
<!--3rd image_Collaboration-->
+
<!--3rd image_COLLABORATION-->
 
<div class="polaroid">
 
<div class="polaroid">
 
    
 
    
−
   <img src="http://s7d5.scene7.com/is/image/ni/iStock_000048642816_Full_16x9?$ni-card-md$&fit=crop" alt="Collaboration" style="width:100%;display: block;height:180px">
+
   <img src="https://static.igem.org/mediawiki/2017/b/be/NUS_2017_IGEM_home_collaboration.png" alt="Collaboration" style="width:100%;display: block;height:180px">
 
    
 
    
 
   <div class="gallery-intro-container">
 
   <div class="gallery-intro-container">
−
     <p>Collaboration</p>
+
     <a href="https://2017.igem.org/Team:NUS_Singapore/Collaborations" >COLLABORATION</a>
 
   </div>
 
   </div>
  
−
   <div class="gallery-overlay" style="background-color: #FA290C">
+
   <div class="gallery-overlay" style="background-color: #c5cae9">
 
     <div class="gallery-overlay-text"><a href="https://2017.igem.org/Team:NUS_Singapore/Collaborations" >Collaboration</a></div>
 
     <div class="gallery-overlay-text"><a href="https://2017.igem.org/Team:NUS_Singapore/Collaborations" >Collaboration</a></div>
 
   </div>
 
   </div>
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</div>
 
</div>
  
−
<!--4th image_Gallery-->
+
<!--4th image_GALLERY-->
 
<div class="polaroid">
 
<div class="polaroid">
 
    
 
    
−
   <img src="https://static.igem.org/mediawiki/2017/2/2b/NUS_IGEM_Lab_2.jpg" alt="gallery" style="width:100%;display: block;height:180px">
+
   <img src="https://static.igem.org/mediawiki/2017/7/7e/NUS_2017_IGEM_home_safety.png" alt="Safety" style="width:100%;display: block;height:180px">
 
    
 
    
 
   <div class="gallery-intro-container">
 
   <div class="gallery-intro-container">
−
     <p>Gallery</p>
+
     <a href="https://2017.igem.org/Team:NUS_Singapore/Safety">SAFETY</a>
 
   </div>
 
   </div>
  
−
   <div class="gallery-overlay" style="background-color: #FAEF0C">
+
   <div class="gallery-overlay" style="background-color: #bbdefb">
−
     <div class="gallery-overlay-text"><a href="#">Gallery</a></div>
+
     <div class="gallery-overlay-text"><a href="https://2017.igem.org/Team:NUS_Singapore/Safety">Safety</a></div>
 
   </div>
 
   </div>
  
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<div class="polaroid">
 
<div class="polaroid">
  
−
   <img src="https://static.igem.org/mediawiki/2017/c/c9/NUS_IGEM_Groupphoto_1.jpeg" alt="team" style="width:100%;display: block;height:180px">
+
   <img src="https://static.igem.org/mediawiki/2017/1/13/NUS_2017_IGEM_home_team.png" alt="team" style="width:100%;display: block;height:180px">
  
 
   <div class="gallery-intro-container">
 
   <div class="gallery-intro-container">
−
    <p>TEAM</p>
+
      <a href="https://2017.igem.org/Team:NUS_Singapore/Team">TEAM</a>
 
   </div>
 
   </div>
  
−
   <div class="gallery-overlay" style="background-color: #8E0489">
+
   <div class="gallery-overlay" style="background-color: #a5d6a7">
 
     <div class="gallery-overlay-text"><a href="https://2017.igem.org/Team:NUS_Singapore/Team">TEAM</a></div>
 
     <div class="gallery-overlay-text"><a href="https://2017.igem.org/Team:NUS_Singapore/Team">TEAM</a></div>
 
   </div>
 
   </div>
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<div class="clear-largespace"></div>
 
<div class="clear-largespace"></div>
  
 +
<!--*************************************  Quick Link Footer ***************** ********************-->
 +
<div class="quicklink">
 +
<p>Quick Link</p>
 +
</div>
 +
 +
<div class="quicklink-container">
 +
<div class="quicklink-1">
 +
<a href="https://2017.igem.org/Team:NUS_Singapore" target="_blank">Home</a><br>
 +
<a href="https://2017.igem.org/Team:NUS_Singapore/Description" target="_blank">Description</a><br>
 +
<a href="https://2017.igem.org/Team:NUS_Singapore/Design" target="_blank">Design</a><br>
 +
<a href="https://2017.igem.org/Team:NUS_Singapore/Experiments" target="_blank">Experiment</a><br>
 +
    </div>
 +
 +
    <div class="quicklink-2">
 +
<a href="https://2017.igem.org/Team:NUS_Singapore/InterLab" target="_blank">Interlab Study</a><br>
 +
<a href="https://2017.igem.org/Team:NUS_Singapore/Parts" target="_blank">Parts</a><br>
 +
<a href="https://2017.igem.org/Team:NUS_Singapore/Notebook" target="_blank">Lab Journal</a><br>
 +
    </div>
 +
 +
    <div class="quicklink-3">
 +
<a href="https://2017.igem.org/Team:NUS_Singapore/Model" target="_blank">Modelling</a><br>
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<a href="https://2017.igem.org/Team:NUS_Singapore/Collaborations" target="_blank">Collaboration</a><br>
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Latest revision as of 16:07, 1 November 2017

Measurement Modelling Medal Check List
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Overview Methodology Kill Switch for Probiotics Kill Switch for BeeT
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Making Engineering of Customised Kill Switches Easier

Many SynBio groups are engineering microbes that could one day be useful in detecting diseases, fighting cancer and monitoring heavy metals in rivers. However, engineered microbes may leak into the non-designated environment, posing threats to our natural ecosystem. This is a major hurdle towards the commercialization of engineered microbes. To address this, we need effective kill switches to prevent engineered microbes from escaping into the environment. However, existing kill switches have limitations and, more importantly, it is difficult to readily tailor make kill switches for different applications.


Currently, there is no harmonized framework for kill switch design and construction. Team NUSgem aims to make engineering of such customised, effective kill switches easier. To this end, we are developing a library of characterized sensors, a killing and verification module which can be used in computer-aided design and modelling tool (such as CELLO and AdvanceSyn Studio ) and can be readily modelled. As a proof of concept, we will focus on developing a kill switch for engineered probiotics for human health.

We are a team of 6 undergraduates and 1 recent graduate student from different disciplines including Biomedical Engineering, Electrical Engineering, Science and Economics.

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