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<h1 style="color:#428bca;"><i>S. aureus</i> Intestinal Colonization</h1> | <h1 style="color:#428bca;"><i>S. aureus</i> Intestinal Colonization</h1> | ||
− | <p>Human intestine is a highly complex microbial ecosystem. It accommodates commensal microflora species, various types of secretory fluids, fermentation metabolites and host defense molecules that promote colonization resistance to pathogenic bacteria. However, <i>Staphylococcus aureus</i>, one of the most opportunistic and invasive pathogens, is capable of disrupting this colonization resistance and infecting the intestine. Patients with <i>S. aureus</i> intestinal colonization suffer from fecal incontinence, diarrhea, pseudomembranous colitis and so on. | + | <p>Human intestine is a highly complex microbial ecosystem. It accommodates commensal microflora species, various types of secretory fluids, fermentation metabolites and host defense molecules that promote colonization resistance to pathogenic bacteria. However, <i>Staphylococcus aureus</i>, one of the most opportunistic and invasive pathogens, is capable of disrupting this colonization resistance and infecting the intestine. Patients with <i>S. aureus</i> intestinal colonization suffer from fecal incontinence, diarrhea, pseudomembranous colitis and so on. |
− | + | <a href="#">Learn more</a></p> | |
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<h1 style="color:#f0ad4e;">Antibiotic Overuse and Superbacteria</h1> | <h1 style="color:#f0ad4e;">Antibiotic Overuse and Superbacteria</h1> | ||
− | <p>Due to antibiotic overuse, <i>Staphylococcus aureus</i> develops resistance to various antibiotics and it becomes increasingly difficult to be eliminated. As a leading cause of hospital-acquired infections, methicillin-resistant <i>S. aureus</i> (MRSA) strains are multi-antibiotic resistant. Even the use of vancomycin — one of the last therapeutic resorts against <i>S. aureus</i>, becomes futile. Worse still, community-acquired MRSA strains are much more virulent and cause more morbidity and mortality than hospital-acquired MRSA. | + | <p>Due to antibiotic overuse, <i>Staphylococcus aureus</i> develops resistance to various antibiotics and it becomes increasingly difficult to be eliminated. As a leading cause of hospital-acquired infections, methicillin-resistant <i>S. aureus</i> (MRSA) strains are multi-antibiotic resistant. Even the use of vancomycin — one of the last therapeutic resorts against <i>S. aureus</i>, becomes futile. Worse still, community-acquired MRSA strains are much more virulent and cause more morbidity and mortality than hospital-acquired MRSA. |
− | + | <a href="#">Learn more</a></p> | |
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<h1 style="color:#5bc0de;">Further Applications</h1> | <h1 style="color:#5bc0de;">Further Applications</h1> | ||
− | <p>Our genetically engineered <i>Lactococcus lactis</i> can be made into medicines, such as enteric coated tablets, together with anti-diarrheal medicines, to cure enteritis. In addition, as an important industrial microorganism, <i>L. lactis</i> can be used as food additives in fermented dairy products such as cheese, and yogurt. When they inhabit in the intestinal tract, not only do they regulate micro-ecological balance, but also prevent or reduce the chance of infection. | + | <p>Our genetically engineered <i>Lactococcus lactis</i> can be made into medicines, such as enteric coated tablets, together with anti-diarrheal medicines, to cure enteritis. In addition, as an important industrial microorganism, <i>L. lactis</i> can be used as food additives in fermented dairy products such as cheese, and yogurt. When they inhabit in the intestinal tract, not only do they regulate micro-ecological balance, but also prevent or reduce the chance of infection. |
− | + | <a href="#">Learn more</a></p> | |
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Revision as of 18:47, 2 August 2017