Line 20: | Line 20: | ||
<p style="font-family: josefin-sans, sans-serif; font-size: 22px"> Science innovation comes from the intersection of practical and theoretical application. Scientists have to consider the ethical implications of their work when solving the issues of today. <br> <br> | <p style="font-family: josefin-sans, sans-serif; font-size: 22px"> Science innovation comes from the intersection of practical and theoretical application. Scientists have to consider the ethical implications of their work when solving the issues of today. <br> <br> | ||
The 2017 NU iGEM team made safety a priority throughout the experience and considered ethics, public safety, and risks. </p> | The 2017 NU iGEM team made safety a priority throughout the experience and considered ethics, public safety, and risks. </p> | ||
+ | </div> | ||
+ | |||
+ | <div class="w3-center w3-margin"> | ||
<h1 class="w3-center w3-margin" style="font-family: aladin, sans-serif;"> Safe Project Design </h1> | <h1 class="w3-center w3-margin" style="font-family: aladin, sans-serif;"> Safe Project Design </h1> | ||
Line 27: | Line 30: | ||
<h1 class="w3-center w3-margin" style="font-family: aladin, sans-serif;"> Off target effects </h1> | <h1 class="w3-center w3-margin" style="font-family: aladin, sans-serif;"> Off target effects </h1> | ||
− | <p "font-family: josefin-sans, sans-serif; font-size: 22px> Off target effects always remain a possibility when it comes to gene editing. Cleaving off unintended DNA could lead to fatal results for a cell. However, our choice of OMVs as a delivery system offers safety checks as an OMV will only be accepted by a bacterial cell. OMV delivery is also advantageous over viral delivery because it allows for transportation of a whole protein; thus the protein is not incorporated in the host cell genome which minimizes off target effects. Effective design of gRNA (guide RNA) will also minimize off target effects. | + | <p style="font-family: josefin-sans, sans-serif; font-size: 22px> Off target effects always remain a possibility when it comes to gene editing. Cleaving off unintended DNA could lead to fatal results for a cell. However, our choice of OMVs as a delivery system offers safety checks as an OMV will only be accepted by a bacterial cell. OMV delivery is also advantageous over viral delivery because it allows for transportation of a whole protein; thus the protein is not incorporated in the host cell genome which minimizes off target effects. Effective design of gRNA (guide RNA) will also minimize off target effects. |
</p> | </p> | ||
Revision as of 20:18, 29 August 2017
Saftey
Science innovation comes from the intersection of practical and theoretical application. Scientists have to consider the ethical implications of their work when solving the issues of today.
The 2017 NU iGEM team made safety a priority throughout the experience and considered ethics, public safety, and risks.
Safe Project Design
Off target effects
Contact us:
Northwestern University
2145 Sheridan Rd, Evanston, IL 60208
Email: nuigem2017@gmail.com
Check us out on Twitter!