Difference between revisions of "Team:Tec-Chihuahua/HP/Silver"

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<h3>★  ALERT! </h3>
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<p>This page is used by the judges to evaluate your team for the <a href="https://2017.igem.org/Judging/Medals">medal criterion</a> or <a href="https://2017.igem.org/Judging/Awards"> award listed above</a>. </p>
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<p> Delete this box in order to be evaluated for this medal criterion and/or award. See more information at <a href="https://2017.igem.org/Judging/Pages_for_Awards"> Instructions for Pages for awards</a>.</p>
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            <h1>HP Silver</h1>
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            <h3>ABSTRACT</h3>
  
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            <p align= "justify">This edition, the Tec-Chihuahua team developed a mathematical model that is focused only in one out of the three enzymes that we study in our project, the aiiA. Using a set of differential equations we managed to simulate a biological system inside <i>Erwinia amylovora</i> where the aiiA enzyme interacts with the quorum sensing phenomenon. The model only includes the performance of this enzyme because of its capacity to inhibit at least two or more of the four virulence factors of E. amylovora. The mathematical system states a basic model capable of simulating and monitoring the general behavior and interaction of an unregulated gene (inhibitor) over a regulated one (inhibited). </p>
  
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            <p align= "justify">Later below and in the following pages, we will describe the behavior of a wild <i>E. amylovora</i> and a modified one, where by means of mathematical modeling we were able to predict the impact of our modification inside our target pathogen.</p>
  
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<h1>Silver Medal Human Practices</h1>
 
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<p>iGEM teams are leading in the area of Human Practices because they conduct their projects within a social/environmental context, to better understand issues that might influence the design and use of their technologies.</p>
 
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<p>Teams work with students and advisors from the humanities and social sciences to explore topics concerning ethical, legal, social, economic, safety or security issues related to their work. Consideration of these Human Practices is crucial for building safe and sustainable projects that serve the public interest. </p>
 
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<p>For more information, please see the <a href="https://2017.igem.org/Competition/Human_Practices">Human Practices page</a>.</p>
 
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<h3>Silver Medal Criterion #3</h3>
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<p>Convince the judges you have thought carefully and creatively about whether your work is safe, responsible and good for the world. You could accomplish this through engaging with your local, national and/or international communities or other approaches. Please note that standard surveys will not fulfill this criteria.</p>
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<h5>Some Human Practices topic areas </h5>
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<h5>What should we write about on this page?</h5>
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<p>On this page, you should write about the Human Practices topics you considered in your project, and document any special activities you did (such as visiting experts, talking to lawmakers, or doing public engagement). This should include all of the work done for the Silver Medal Criterion #3. Details for your Gold medal work and/or work for the two Human Practices special prizes should be put on those specified pages.</p>
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<h5>Inspiration</h5>
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<p>Read what other teams have done:</p>
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<li><a href="https://2014.igem.org/Team:Dundee/policypractice/experts">2014 Dundee </a></li>
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<li><a href="https://2014.igem.org/Team:UC_Davis/Policy_Practices_Overview">2014 UC Davis </a></li>
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<li><a href="https://2013.igem.org/Team:Manchester/HumanPractices">2013 Manchester </a></li>
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<li><a href="https://2013.igem.org/Team:Cornell/outreach">2013 Cornell </a></li>
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Revision as of 21:57, 21 October 2017

HP Silver

ABSTRACT

This edition, the Tec-Chihuahua team developed a mathematical model that is focused only in one out of the three enzymes that we study in our project, the aiiA. Using a set of differential equations we managed to simulate a biological system inside Erwinia amylovora where the aiiA enzyme interacts with the quorum sensing phenomenon. The model only includes the performance of this enzyme because of its capacity to inhibit at least two or more of the four virulence factors of E. amylovora. The mathematical system states a basic model capable of simulating and monitoring the general behavior and interaction of an unregulated gene (inhibitor) over a regulated one (inhibited).

Later below and in the following pages, we will describe the behavior of a wild E. amylovora and a modified one, where by means of mathematical modeling we were able to predict the impact of our modification inside our target pathogen.

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