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− | <head>
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− | <meta charset="UTF-8" />
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− | <meta name="viewport" content="width=device-width, initial-scale=1.0">
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− | <meta http-equiv="Content-Type" content="text/html; charset=utf-8" />
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− | <meta name="generator" content="MediaWiki 1.16.5" />
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− | <link rel="shortcut icon" href="/favicon.ico" />
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− | <link rel="search" type="application/opensearchdescription+xml" href="/wiki/opensearch_desc.php" title="2014.igem.org (en)" />
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− | <link title="Creative Commons" type="application/rdf+xml" href="/wiki/index.php?title=WikitemplateA_home&action=creativecommons" rel="meta" />
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− | <link rel="copyright" href="http://creativecommons.org/licenses/by/3.0/" />
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− | <link rel="alternate" type="application/atom+xml" title="2014.igem.org Atom feed" href="/wiki/index.php?title=Special:RecentChanges&feed=atom" /> <title>WikitemplateA home - 2014.igem.org</title>
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− | <link rel="stylesheet" type="text/css" media="print" href="/wiki/skins/common/commonPrint.css?270" />
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− | <script type="text/javascript" src="/wiki/skins/common/wikibits.js?270"><!-- wikibits js --></script>
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− | <script src="/wiki/skins/common/mwsuggest.js?270"></script>
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− | <div id="top-section">
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− | <div class="right-menu noprint" id="menubar">
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− | <ul>
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− | <li id="pt-login"><a href="/wiki/index.php?title=Special:UserLogin&returnto=WikitemplateA_home" title="You are encouraged to log in; however, it is not mandatory [o]" accesskey="o">Log in</a></li> </ul>
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− | </div><!-- end right menubar -->
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− | <div id="search-controls" class="noprint">
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− | </div> <!-- close top-section-->
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− | <div id="content">
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− | <a name="top" id="top"></a>
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− | <h1 class="firstHeading">WikitemplateA home</h1>
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− | <div id="bodyContent">
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− | <h3 id="siteSub" class='noprint'>From 2014.igem.org</h3>
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− | <div id="contentSub"></div>
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− | <!--
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− | <div id="jump-to-nav">Jump to: <a href="#column-one">navigation</a>, <a href="#searchInput">search</a></div>-->
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− | <p>
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− | <!-- this section changes the default wiki template to a
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− | <style type="text/css">
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− | #contentSub, #footer-box, #catlinks, #search-controls, #p-
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− | logo, #sideMenu, #menubar, .logo_2017, .printfooter, .firstHeading,.visualClear {display:
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− | none;} /*-- hides default wiki settings --*/
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− |
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− | #top-section { /*-- styling for default menu bar (edit, page,
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− | history, etc.) --*/
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− | border: 0 none;
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− | height: 14px;
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− | z-index: 100;
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− | top: 0;
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− | position: fixed;
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− | width: 975px;
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− | left: 50%;
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− | margin-left: -487px;
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− | }
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− | #globalWrapper, #content { /*-- changes default wiki settings
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− | width: 100%;
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− | height: 100%;
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− | border: 0px;
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− | background-color: transparent;
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− | margin: 0px;
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− | padding: 0px;
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− | }
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− |
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− | html, body, .wrapper { /*-- changes default wiki settings --
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− |
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− | */
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− | width: 100%;
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− | height: 100%;
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− | background-color: transparent;
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− | }
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− | </style>
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− |
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− | <link rel="stylesheet" type="text/css" href="https://2015.igem.org/Template:Heidelberg/css/jasnybootstrapmin?action=raw&ctype=text/css" />
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− | <link rel="stylesheet" type="text/css" href="https://2015.igem.org/Template:Heidelberg/css/bootstrapmin?action=raw&ctype=text/css" />
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− | <script type="text/javascript" src="https://2015.igem.org/Template:Heidelberg/js/jasnybootstrapmin?action=raw&ctype=text/javascript"></script>
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− | <!-- Assets -->
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− | <link rel="stylesheet" href="http://static.tildacdn.com/css/tilda-grid-3.0.min.css" type="text/css" media="all" />
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− | <link rel="stylesheet" href="https://fonts.googleapis.com/css?family=Josefin+Sans:300,400|Roboto:300,400,500">
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− | <link rel="stylesheet" href="http://azmind.com/demo/bootstrap-navbar-menu/layout-3/assets/font-awesome/css/font-awesome.min.css">
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− | <!-- Favicon and touch icons -->
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− | <link rel="stylesheet" type="text/css" href="https://2017.igem.org/Template:Heidelberg/styles2/CSS?action=raw&ctype=text/css">
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− | <script type="text/javascript" src="https://2015.igem.org/Template:Heidelberg/js/jasnybootstrapmin?action=raw&ctype=text/javascript"></script>
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− | <!-- jQuery CDN -->
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− | <script src="https://code.jquery.com/jquery-1.12.0.min.js"></script>
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− | <!-- Bootstrap Js CDN -->
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− | right: 50px;
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− | width: 400px;
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− | #textblock1 > p, #textblock3 > p, #textblock5 > p,#textblock2 > p, #textblock4 > p, #textblock6 > p, #textblock7 > p, #textblock8 > p {
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− | font-size: 26px !important;
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− | font-size: 60px !important;
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− | background: url('') no-repeat;
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− | #Icon1 {
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− | width: 400px;
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− | left: 1%;
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− | #Icon3 {
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− | position: absolute;
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− | left: 4%;
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− | width: 400px;
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− | width: 300px;
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− | right: 0px;
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− | line-height: 40px !important;
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− | #Icon1:hover > .icon-text p,#Icon2:hover > .icon-text p,#Icon3:hover > .icon-text p,#Icon4:hover > .icon-text-right p,#Icon5:hover > .icon-text-right p,#Icon6:hover > .icon-text-right p {
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− | opacity: 1 !important;
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− | text-align: center;
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− | transition: opacity 1s ease;
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− | #Icon1 > .icon-text p,#Icon2 > .icon-text p,#Icon3 > .icon-text p,#Icon4 > .icon-text-right p,#Icon5 > .icon-text-right p,#Icon6 > .icon-text-right p {
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− | font-family: 'Josefin Sans' !important;
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− | #Icon2 > .icon-text h5 {
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− | color: #b2cbdd !important;
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− | font-weight: 400 !important;
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− | line-height: 40px !important;
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− | #Icon3 > .icon-text h5 {
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− | text-transform: uppercase;
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− | line-height: 40px !important;
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− | }
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− | font-weight: 400 !important;
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− | }
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− |
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− | #Icon5 > .icon-text-right h5 {
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− | text-transform: uppercase;
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− | color: #fef39b !important;
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− | min-height: 600px ;
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− | width: 100%;
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− | max-width: 1200px;
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− | margin: 0 auto;
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− | left: 380px;
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− | width: 500px;
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− | top: 10%
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− |
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− | .icon {
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− | cursor: pointer;
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− | }
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− | .toolbox-icon {
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− | width: 120px;
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− | height: 120px;
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− | border-radius: 100%;
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− | float: left;
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− | background-color: white;
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− | position: absolute;
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− | transform: scale(1.2,1.2);
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− | transition: all 1s ease-out;
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− | @media (max-width: 1200px) {
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− | #wrapper {
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− | padding-bottom: 600px;
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− |
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− |
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− |
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− | #textblock1 {
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− | position: absolute;
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− | top: 50px;
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− | left: 0px;
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− | width: 400px;
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− | #textblock1 > p, #textblock2 > p, #textblock3 > p,#textblock4 > p, #textblock5 > p,#textblock6 > p,#textblock7 > p,#textblock8 > p,#textblock9 > p {
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− | color: white !important;
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− |
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− |
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− | font-size: 24px !important;
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− | font-weight: 300 !important;
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− | }
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− |
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− | #textblock1 > a, #textblock2 > a,#textblock3 > a, #textblock4 > a,#textblock5 > a,#textblock6 > a,#textblock7 > a,#textblock8 > a,#textblock9 > a {
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− | line-height: 50px !important;
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− | font-size: 50px !Important;
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− |
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− | #textblock2 {
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− | top: 800px;
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− | left: 150px;
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− | top: 780px;
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− | right: 0px;
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− | width: 300px;
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− | height: 220px;
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− | width: 400px;
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− | right: 0px;
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− | left: 0px;
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− | <source src="https://static.igem.org/mediawiki/2017/2/25/T--Heidelberg--2017_Wiki_Intro_iGEM2017.mp4" type="video/mp4">
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− | <img src="https://static.igem.org/mediawiki/2017/6/6d/T--Heidelberg--2017_Phage_on_top2.svg" class="phage-scroller"></a>
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− | <img width="100%" src="https://static.igem.org/mediawiki/2017/c/cc/T--Heidelberg--2017_Red_Thread3.svg">
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− | <div class="textblock" id="textblock1">
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− | <p style="padding-bottom: 10px" class="aligner-left">Life shows an astonishing diversity and complexity, resulting from millions of years of random mutation and selection.</p><p> We, <a href="https://2017.igem.org/Team:Heidelberg/Team" class="sublink" style="color: #f8991d !important">the iGEM Team Heidelberg</a>,</p>
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− | <a href="https://2017.igem.org/Team:Heidelberg/Description" id="accelerated_evolution"><strong>Accelerate Evolution</strong></a>
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− | <p>to drive <a href="https://2017.igem.org/Team:Heidelberg/Achievements" class="sublink" style="color: #f8991d !important">Innovation</a> for human benefit</p>
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− | <a href="https://2017.igem.org/Team:Heidelberg/Description" style="color: white !important; padding: 20px; background-color: #f8991d !important; border-radius: 5px;font-size: 30px !important;">Explore our project</a>
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− | </div>
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− | <div class="textblock" id="textblock2">
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− | <a href="https://2017.igem.org/Team:Heidelberg/Design"><strong>Curious how?</strong></a>
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− | <p style="padding-top: 30px" class="aligner-left">To speed up and direct evolution, we use <a href="https://2017.igem.org/Team:Heidelberg/Pace" class="sublink" style="color: #fbb74b !important">phage-assisted continuous evolution</a> and our newly created & simple method called <a href="https://2017.igem.org/Team:Heidelberg/Predcel" class="sublink" style="color: #fbb74b !important">PREDCEL</a></p>
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− | <div id="textblock3" style="z-index: 2;">
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− | <video poster="" style="position:absolute;" controls>
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− | <source src="https://static.igem.org/mediawiki/2017/a/a9/T--Heidelberg--2017_1st_Video_iGEM_lq.mp4" type="video/mp4">
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− | <p style="font-family: 'Josefin Sans' !important; font-size: 20px !important; color: white; position: absolute; bottom: -44px; text-align: center;"> <a style="font-size: 20px; font-family: 'Josefin Sans' !important; color: #fbb74b; text-decoration: underline;" href="https://2017.igem.org/Team:Heidelberg/Design">Klick here</a> for our second video!</p>
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− | <p>No way to be fast enough without</p><a href="https://2017.igem.org/Team:Heidelberg/Model"><strong>Modeling</strong></a><p class="aligner-left"> Learn how we optimized our experimental parameters using ODE models calibrated with wet lab data.</p><p class="aligner-left"> And the best: Our interactive models run <a href="https://2017.igem.org/Team:Heidelberg/Model/Tools" class="sublink" style="color: #9d1c20 !important">entirely in your browser!</a></p>
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− | <p>Still too slow? Meet our Artificial Intelligence for Genetic Evolution Mimicking,</p><a href="https://2017.igem.org/Team:Heidelberg/Software" id="artificial_intelligence"><strong>AiGEM!</strong></a><p style="padding-top: 10px;" class="aligner-right"> AiGEM comprises a<a href="https://2017.igem.org/Team:Heidelberg/Software/DeeProtein" class="sublink" style="color: #ffd700 !important"> deep neuronal network</a> and accompanying <a href="https://2017.igem.org/Team:Heidelberg/Software/GAIA" class="sublink" style="color: #ffd700 !important">genetic algorithm</a> able to fast-forward directed evolution in silico</p><p class="aligner-right"> Not convinced yet?
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− | Check out our fully in silico evolved, optimized <a href="https://2017.igem.org/Team:Heidelberg/Validation#lac" class="sublink" style="color: #ffd700 !important">Beta-lactamase</a> and reprogrammed <a href="https://2017.igem.org/Team:Heidelberg/Validation#gusgal" class="sublink" style="color: #ffd700 !important">Beta-glucuronidase!</a></p>
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− | <div class="textblock" id="textblock6">
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− | <p>To make a difference, we need to consider the whole</p> <a href="https://2017.igem.org/Team:Heidelberg/Human_Practices"><strong>Colorful Picture</strong></a><p style="padding-top: 10px;" class="aligner-left">Our integrated human practice activities helped us to make our technology <a href="https://2017.igem.org/Team:Heidelberg/Safety" class="sublink" style="color:#6698be !important">safer</a> and stimulate its <a href="https://2017.igem.org/Team:Heidelberg/Interviews" class="sublink" style="color:#6698be !important">responsible use</a>, ideally to address urgent human needs.</p>
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− | <div class="textblock" id="textblock7">
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− | <a href="https://2017.igem.org/Team:Heidelberg/Organosilicones"><strong>Our Applications:</strong></a>
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− | <p class="aligner-right">Evolving novel cytochromes with help of <a href="https://2017.igem.org/Team:Heidelberg/Software/MAWS" class="sublink" style="color: #F8991D !important">in silico predicted riboswitches</a>, to enable fully biological production of <a href="https://2017.igem.org/Team:Heidelberg/Organosilicones" class="sublink" style="color: #F8991D !important">organosilicons</a>. Using T7 polymerase as modular platform, we also showcase the evolution of improved <a href="https://2017.igem.org/Team:Heidelberg/Protein_Interaction" class="sublink" style="color: #F8991D !important">protein-protein interaction.</a></p>
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− | </div>
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− | <div class="textblock" id="textblock8">
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− | <p class="aligner-left"> Now it’s on you. Our toolbox guide and RFC help you to get started.</p>
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− | </div>
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− | <div class="textblock" id="textblock9">
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− | <a href="https://2017.igem.org/Team:Heidelberg/Toolbox"><strong>Learn. </strong><strong>Evolve.</strong><strong> PREDCEL! </strong></a>
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− | </div>
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− | <div id="toolbox">
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− | <div style="position: relative;" id="toolbox-row1">
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− | <div id="Icon1" class="icon"><a href="https://2017.igem.org/Team:Heidelberg/Protein_Interaction"><img src="https://static.igem.org/mediawiki/2017/4/4b/T--Heidelberg--2017_T--Heidelberg--2017_Icon_Protein_Interaction.svg" class="toolbox-icon" style="left: 0px;"></a><div class="icon-text" style="width: 300px;"><a href="https://2017.igem.org/Team:Heidelberg/Protein_Interaction"><h5>Protein Interaction</h5><p>Evolve specific binding</p></a></div></div>
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− | <div id="Icon4" class="icon"> <a href="https://2017.igem.org/Team:Heidelberg/Cytochrome_Engineering"><img src="https://static.igem.org/mediawiki/2017/9/9c/T--Heidelberg--2017_T--Heidelberg--2017_Icon_Product_Specificity.svg" class="toolbox-icon" style="left: 280px;"></a><div class="icon-text-right"> <a href="https://2017.igem.org/Team:Heidelberg/Cytochrome_Engineering"><h5>Cytochrome Engineering</h5><p>Turning promiscous enzymes into specific biofactories</p></a></div></div>
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− | <div id="Icon2" class="icon"><a href="https://2017.igem.org/Team:Heidelberg/Optogenetics"><img src="https://static.igem.org/mediawiki/2017/3/38/T--Heidelberg--2017_T--Heidelberg--2017_Icon_Opto_Genetics.svg" class="toolbox-icon" style="left: 0px;"></a><div class="icon-text" style="width: 300px;"><a href="https://2017.igem.org/Team:Heidelberg/Optogenetics"><h5>Opto-Genetics</h5><p>Adapt selection stringency with light</p></a></div></div>
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− | <div id="Icon5" class="icon"><a href="https://2017.igem.org/Team:Heidelberg/Organosilicones"><img src="https://static.igem.org/mediawiki/2017/e/e9/T--Heidelberg--2017_T--Heidelberg--2017_Icon_Carbonsilicones.svg" class="toolbox-icon" style="left: 270px;"></a><div class="icon-text-right"><a href="https://2017.igem.org/Team:Heidelberg/Organosilicones"><h5>Organo silicones</h5><p>Teaching nature carbonsilicon chemistry</p></a></div></div>
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− | <div id="Icon3" class="icon"> <a href="https://2017.igem.org/Team:Heidelberg/CRISPR"><img src="https://static.igem.org/mediawiki/2017/c/cd/T--Heidelberg--2017_T--Heidelberg--2017_Icon_DNA_Editing.svg" class="toolbox-icon" style="left: 0px;"></a><div class="icon-text" style="width: 230px;"> <a href="https://2017.igem.org/Team:Heidelberg/CRISPR"><h5>CRISPR Cas9</h5><p>Towards next-generation nucleases</p></a></div></div>
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− | <div id="Icon6" class="icon"><a href="https://2017.igem.org/Team:Heidelberg/RFC"><img src="https://static.igem.org/mediawiki/2017/2/27/T--Heidelberg--2017_Icon_RFC.svg" class="toolbox-icon" style="left: 280px;"></a><div class="icon-text-right"><a href="https://2017.igem.org/Team:Heidelberg/RFC"><h5>RFC</h5><p>Our in vivo Evolution Standard</p></a></div></div>
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