Difference between revisions of "Team:ASIJ TOKYO/Parts"
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<a href="https://2017.igem.org/Team:ASIJ_TOKYO/Notebook">Notebook</a> | <a href="https://2017.igem.org/Team:ASIJ_TOKYO/Notebook">Notebook</a> | ||
<a href="https://2017.igem.org/Team:ASIJ_TOKYO/Results">Results</a> | <a href="https://2017.igem.org/Team:ASIJ_TOKYO/Results">Results</a> | ||
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Revision as of 08:56, 31 October 2017
Basic Parts
Basic parts are defined as "functional unit[s] of DNA that cannot be subdivided into smaller component parts."
Basic Parts
BBa_K2226003 - COX-2 gene
This part consists of the gene for cyclooxygenase-2 (COX-2), an enzyme that is found in elevated levels during inflammation, predominantly found in gastric mucosa and kidneys.
BBa_K2226004 - c-Myc gene
This part consists of the mutated c-Myc gene, which is a regulator gene that codes for a transcription factor. The expressed protein controls multiple functions including cell cycle progression, apoptosis, and cellular transformation. The mutated version of c-Myc is expressed constitutively in many cancers.
BBa_K2226001 - COX-2 promoter and BBa_K2226002 - c-Myc promoter
These parts promote the transcription of the COX-2 gene while binding to reporter system FkBP-Cluc394, and regulate transcription of the c-Myc gene while binding to reporter system FRB-Nluc398, respectively.
Composite Parts
Composite parts are defined as "functional unit[s] of DNA consisting of two or more basic parts assembled together."
