Difference between revisions of "Team:Chalmers-Gothenburg/HP/Silver"

Line 1,081: Line 1,081:
 
h2 {
 
h2 {
 
text-align:left;
 
text-align:left;
         font-size:20pt;
+
         font-size:18pt;
 
}
 
}
  
Line 1,669: Line 1,669:
 
         <div id="nav-anchor">
 
         <div id="nav-anchor">
 
           <nav>
 
           <nav>
            <a href="#intro" class="active">Introduction</a>
 
 
             <a href="#outreach">Outreach</a>
 
             <a href="#outreach">Outreach</a>
 
             <a class="sub-level" href="#university">University Outreach</a>
 
             <a class="sub-level" href="#university">University Outreach</a>
 
             <a class="sub-level" href="#public">Public Outreach</a>
 
             <a class="sub-level" href="#public">Public Outreach</a>
 +
            <a href="#safety">Safety</a>
 +
            <a href="#references">References</a>
 
           </nav>
 
           </nav>
 
         </div>
 
         </div>
Line 1,678: Line 1,679:
 
        
 
        
 
       <div class="wrap-content">
 
       <div class="wrap-content">
 +
     
 
       <div class="dashed_line_left_first">
 
       <div class="dashed_line_left_first">
        <div class="target" id="intro">
 
        <h4 class="subtitle">Introduction</h4>
 
        <p class="text">Pellentesque habitant morbi tristique senectus
 
        et netus et malesuada fames ac turpis egestas. Sed consequat
 
        mattis interdum. Aliquam et velit fermentum velit imperdiet
 
        rhoncus. Donec accumsan molestie ornare. Duis eu odio in tortor
 
        ullamcorper aliquam. Vivamus molestie fermentum urna, vitae
 
        commodo mauris consequat in. Curabitur porttitor pulvinar purus,
 
        ut varius nibh tempus id. Nulla dictum lectus ut erat condimentum,
 
        sit amet euismod nibh eleifend. Maecenas molestie efficitur urna
 
        vel semper. Nullam in turpis eleifend, venenatis ex tincidunt,
 
        tristique sapien. Suspendisse eget facilisis dolor. Integer congue
 
        nisi eu magna consectetur, a bibendum nibh accumsan. Vivamus
 
        fermentum metus id lectus porttitor congue. Pellentesque habitant morbi
 
        tristique senectus et netus et malesuada fames ac turpis egestas. Nulla
 
        metus quam, dapibus ac volutpat ut, dapibus sit amet felis.</p>
 
        </div>
 
      </div>
 
     
 
      <div class="dashed_line_right">
 
 
         <div class="target" id="outreach">
 
         <div class="target" id="outreach">
 
         <h4 class="subtitle">Outreach</h4>
 
         <h4 class="subtitle">Outreach</h4>
Line 1,707: Line 1,689:
 
       </div>  
 
       </div>  
 
        
 
        
<div class="dashed_line_left">
+
<div class="dashed_line_right">
 
         <div class="target" id="university">
 
         <div class="target" id="university">
 
           <h2 class="h2style">University outreach</h2>  
 
           <h2 class="h2style">University outreach</h2>  
Line 1,723: Line 1,705:
 
       </div>
 
       </div>
  
       <div class="dashed_line_right">
+
       <div class="dashed_line_left">
 
         <p class="text">
 
         <p class="text">
 
Even though the lunch lecture was great, the team was not content with only reaching out to biotechnology students was enough. Therefore we reached out to <b>Chalmers Public Relations</b> section and they made a <b>mini series</b> in three parts which they distributed on their Facebook page. This way, we reached a broader crowd, both within and outside the university. In the two first episodes we explain our project, our achievements and <b>plan for the Jamboree in Boston</b>. The last episode will be released after Boston, where the viewers will see how great the Jamboree in Boston was.  
 
Even though the lunch lecture was great, the team was not content with only reaching out to biotechnology students was enough. Therefore we reached out to <b>Chalmers Public Relations</b> section and they made a <b>mini series</b> in three parts which they distributed on their Facebook page. This way, we reached a broader crowd, both within and outside the university. In the two first episodes we explain our project, our achievements and <b>plan for the Jamboree in Boston</b>. The last episode will be released after Boston, where the viewers will see how great the Jamboree in Boston was.  
Line 1,731: Line 1,713:
  
 
         <div class="target" id="public">
 
         <div class="target" id="public">
<div class="dashed_line_left">
+
<div class="dashed_line_right">
 
           <h2 class="h2style">Public outreach</h2>  
 
           <h2 class="h2style">Public outreach</h2>  
 
         <h2>
 
         <h2>
Line 1,744: Line 1,726:
 
         </div>
 
         </div>
  
<div class="dashed_line_right">
+
<div class="dashed_line_left">
 
         <p class="text">
 
         <p class="text">
 
The lecture continued with <b>future applications</b> of synthetic biology and the <b>ethical aspects</b> were discussed. Research and responsibility goes hand in hand and the main message of this part was that it is important to think and discuss ethical dilemmas and questions before conducting any experiment. Different views on different subjects were presented in a natural way to let the audience create their own opinion. The lecture ended with a talk about <b>scientific communication</b>; how the communication work between researchers and the public today and why it is important to establish such a conversation.
 
The lecture continued with <b>future applications</b> of synthetic biology and the <b>ethical aspects</b> were discussed. Research and responsibility goes hand in hand and the main message of this part was that it is important to think and discuss ethical dilemmas and questions before conducting any experiment. Different views on different subjects were presented in a natural way to let the audience create their own opinion. The lecture ended with a talk about <b>scientific communication</b>; how the communication work between researchers and the public today and why it is important to establish such a conversation.
Line 1,753: Line 1,735:
 
       </div>
 
       </div>
  
<div class="dashed_line_left">
+
<div class="dashed_line_right">
 
         <h2>
 
         <h2>
 
           Survey Lung cancer
 
           Survey Lung cancer
Line 1,762: Line 1,744:
 
         </div>
 
         </div>
  
<div class="dashed_line_right">
+
<div class="dashed_line_left">
 
         <p class="text">
 
         <p class="text">
 
We <b>collaborated</b> with iGEM Bilkent-UNAMBG and let them distribute the survey in their country to see if the results would differ between countries. The participation was good, with 605 and 268 participants in Sweden and Turkey respectively.  
 
We <b>collaborated</b> with iGEM Bilkent-UNAMBG and let them distribute the survey in their country to see if the results would differ between countries. The participation was good, with 605 and 268 participants in Sweden and Turkey respectively.  
Line 1,777: Line 1,759:
  
  
<div class="dashed_line_left">
+
<div class="dashed_line_right">
 
         <p class="text">
 
         <p class="text">
 
When asked the following question: “Do you think such a screening program should be totally financed or subsidized by the government?” the result showed that <b>most</b> of the participants think a lung cancer screening program should be either <b>funded or subsidized by the government</b> (Figure 2). The large difference between the countries is that most participants for Sweden think a subsidization would be the best while majority from Turkey believe that the whole screening program should be financed by the government. Overall, there seems to be a positive attitude about setting up a lung screening program in both countries.  
 
When asked the following question: “Do you think such a screening program should be totally financed or subsidized by the government?” the result showed that <b>most</b> of the participants think a lung cancer screening program should be either <b>funded or subsidized by the government</b> (Figure 2). The large difference between the countries is that most participants for Sweden think a subsidization would be the best while majority from Turkey believe that the whole screening program should be financed by the government. Overall, there seems to be a positive attitude about setting up a lung screening program in both countries.  
Line 1,787: Line 1,769:
 
</figure>
 
</figure>
 
         </div>
 
         </div>
 +
 +
        <div class="target" id="safety">
 +
      <div class="dashed_line_left">
 +
        <h4 class="subtitle">Safety</h4>
 +
        <p class="text">
 +
A vital part of working with the project and creating a screening program was to <b>take the safety into consideration</b>. It is important to ensure that <b>neither patients, hospital nor lab workers would be exposed to any risks.</b>
 +
        </p>
 +
        <p class="text">
 +
The first step was to make sure that neither patients or physicians would be in contact with the genetically modified yeast created in this project. If the risk of exposure is removed, it will also simplify the regulation issues. The exposure will be reduced using a prototype with a specific filter that will bind the VOCs when breathed on by the patient. This design allows the patient to breath into the prototype several times to increase the amount of VOCs trapped in the filter. The filter can then be sent to laboratory facilities where the VOCs are dissolved and exposed to the yeast to enable detection. See a more detailed description of the method in <a href="https://2017.igem.org/Team:Chalmers-Gothenburg/HP/Gold_Integrated">Integrated human practices, the prototype</a>. With this design the need to bring genetically modified yeast into a hospital environment is made redundant. In Sweden a specific approval is needed to be able to work with genetically modified organisms and it would be the most efficient to use laboratory facilities that already have this approval [1]. Another benefit with this design is that there is absolutely <b>no risk for patients to inhale</b> the genetically modified yeast. 
 +
        </p>
 +
        </div>
 +
 +
      <div class="dashed_line_left">
 +
        <p class="text">
 +
The second step was to ensure that the yeast used as a biosensor is in <b>no way dangerous to the environment</b> or to </b>the people working with it in the laboratory facilities</b>. Risk assessment of the procedures connected to the biosensor show the normal risk associated with working in a laboratory environment. With the </b>right knowledge, correct safety clothing</b> and <b>precautions</b>, the laboratory personnel should <b>not be exposed to any harm</b>. 
 +
        </p>
 +
        <p class="text">
 +
When working with genetically modified organisms it is important to consider the ethical aspects and acknowledge possible hazards for the environment. In this case, <b>the yeast should be limited to the laboratory environment and not be spread or get in contact with nature. </b>
 +
        </p>
 +
        </div>
 +
      </div>
 +
 +
      <div class="dashed_line_right_last">
 +
        <div class="target" id="references">
 +
        <h4 class="subtitle">References</h4>
 +
            <div class="reference_list">
 +
              <ul>
 +
                <li>[1]&#160;&#160; Innesluten användning av genetiskt modifierade mikroorganismer (AFS 2011:2) [Internet]. Stockholm: Anna Middelman [cited 170920]. Available from: https://www.av.se/globalassets/filer/publikationer/foreskrifter/innesluten-anvandning-av-genetiskt-modifierade-mikroorganismer-afs2011-2.pdf.
 +
</li>
 +
              </ul>
 +
            </div>
 +
        </div>
 +
      </div>
  
 
</div>
 
</div>

Revision as of 16:46, 20 October 2017

Chalmers Gothenburg iGEM 2017

HUMAN PRACTICES
Human practices

Outreach

An important part of every iGEM project is to spread information about synthetic biology and its applications to the public. It is also important to reach out to the public and tell them about your own project and answer the questions that they might have and establish a dialogue. To do this we did some outreach to the university and the public through different channels and in different ways.

University outreach

We wanted to make our whole university aware of the cool project that we were working on and therefore decided to spread information about iGEM and our BREATHtaking biosensor. We did this in two ways; by having a lunch lecture and and also making a mini series about the project in cooperation with Chalmers University of Technology.

The lunch lecture was about iGEM and our project and was conducted for Chalmers students, primarily biotechnology students. We answered questions and encouraged the students to get interested in synthetic biology, to support us and join the team next year.

Chalmers presentation

Even though the lunch lecture was great, the team was not content with only reaching out to biotechnology students was enough. Therefore we reached out to Chalmers Public Relations section and they made a mini series in three parts which they distributed on their Facebook page. This way, we reached a broader crowd, both within and outside the university. In the two first episodes we explain our project, our achievements and plan for the Jamboree in Boston. The last episode will be released after Boston, where the viewers will see how great the Jamboree in Boston was.

Public outreach

Lecture about synthetic biology with team iGEM Lund

We collaborated with team iGEM Lund and held a lecture about synthetic biology in Lund at Lunds University’s 350 year anniversary. The lecture was open for the public and the information was kept at a popular scientific level. The lecture started with the history of traditional genetic engineering and continued with the description of synthetic biology. When the audience understood the concept of synthetic biology, each iGEM team presented their own project and how they used synthetic biology.

Lund presentation

The lecture continued with future applications of synthetic biology and the ethical aspects were discussed. Research and responsibility goes hand in hand and the main message of this part was that it is important to think and discuss ethical dilemmas and questions before conducting any experiment. Different views on different subjects were presented in a natural way to let the audience create their own opinion. The lecture ended with a talk about scientific communication; how the communication work between researchers and the public today and why it is important to establish such a conversation.

After the lecture, the audience had the possibility to talk with the speakers and either ask questions or discuss specific subjects. There were questions about the project and some discussion about ethics, showing that the audience got interested and started to form their own opinions.

Survey Lung cancer

To further reach out to the public and to get their help when designing a screening program, we created a survey about lung cancer screening program. We wanted to see what the public thought about having regular examinations for lung cancer, similar to how we screen for breast cancer in Sweden. We also investigated if the public thought that the tax money should finance or subsidized these screenings. This survey was open for everyone to answer and spread via different communication channels. A few more results from the survey is presented in Integrated Human Practices, Screening Program.

We collaborated with iGEM Bilkent-UNAMBG and let them distribute the survey in their country to see if the results would differ between countries. The participation was good, with 605 and 268 participants in Sweden and Turkey respectively.

When asking the question: “If you would have been called for a free regular medical checkup (screening) for lung cancer every year, would you go?”, both countries showed identical results (Figure 1). The majority of the participants (89 %) in the survey would go to the medical check-up, showing a positive attitude for the screening program.

Survey answers
Figure 1. Results for question: “If you would have been called for a free regular medical checkup (screening) for lung cancer every year, would you go?”

When asked the following question: “Do you think such a screening program should be totally financed or subsidized by the government?” the result showed that most of the participants think a lung cancer screening program should be either funded or subsidized by the government (Figure 2). The large difference between the countries is that most participants for Sweden think a subsidization would be the best while majority from Turkey believe that the whole screening program should be financed by the government. Overall, there seems to be a positive attitude about setting up a lung screening program in both countries.

Survey answers
Figure 2. Results for question: “Do you think such a screening program should be totally financed or subsidized by the government?”

Safety

A vital part of working with the project and creating a screening program was to take the safety into consideration. It is important to ensure that neither patients, hospital nor lab workers would be exposed to any risks.

The first step was to make sure that neither patients or physicians would be in contact with the genetically modified yeast created in this project. If the risk of exposure is removed, it will also simplify the regulation issues. The exposure will be reduced using a prototype with a specific filter that will bind the VOCs when breathed on by the patient. This design allows the patient to breath into the prototype several times to increase the amount of VOCs trapped in the filter. The filter can then be sent to laboratory facilities where the VOCs are dissolved and exposed to the yeast to enable detection. See a more detailed description of the method in Integrated human practices, the prototype. With this design the need to bring genetically modified yeast into a hospital environment is made redundant. In Sweden a specific approval is needed to be able to work with genetically modified organisms and it would be the most efficient to use laboratory facilities that already have this approval [1]. Another benefit with this design is that there is absolutely no risk for patients to inhale the genetically modified yeast.

The second step was to ensure that the yeast used as a biosensor is in no way dangerous to the environment or to the people working with it in the laboratory facilities. Risk assessment of the procedures connected to the biosensor show the normal risk associated with working in a laboratory environment. With the right knowledge, correct safety clothing and precautions, the laboratory personnel should not be exposed to any harm.

When working with genetically modified organisms it is important to consider the ethical aspects and acknowledge possible hazards for the environment. In this case, the yeast should be limited to the laboratory environment and not be spread or get in contact with nature.

References

  • [1]   Innesluten användning av genetiskt modifierade mikroorganismer (AFS 2011:2) [Internet]. Stockholm: Anna Middelman [cited 170920]. Available from: https://www.av.se/globalassets/filer/publikationer/foreskrifter/innesluten-anvandning-av-genetiskt-modifierade-mikroorganismer-afs2011-2.pdf.