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| − | {{Template:Cologne-Duesseldorf/header}}
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| − | <html>
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| − | <div id="overlay"></div>
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| − | <div id="paper">
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| − | <img src="https://static.igem.org/mediawiki/2017/0/0d/T--Cologne-Duesseldorf--artico-logo-cities.svg">
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| − | </section>
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| − | <section id="article">
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| − | <h3>Designing a Customizable Synthetic Cell Compartment Toolbox</h3>
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| − | <hr>
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| − | <p>
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| − | Synthetic organisms provide a wide range of applications with the potential to tackle
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| − | the biggest challenges humanity faces. Their creation is therefore one of the major
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| − | goals in synthetic biology. Many breakthroughs have been achieved in the last
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| − | decade, however, the <strong>creation of a fully synthetic cell is yet a milestone to reach for.</strong>
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| − | <br>
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| − | A common approach tries to build up artificial cells from scratch, whereas we want to
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| − | start by engineering artificial compartments through orthogonalization. For designing
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| − | these new compartments we plan to establish an open source toolbox accessible to
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| − | the community at large. This will make it possible to boot up a compartment perfectly
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| − | tailored for a specific application, which will enable cheaper and more efficient
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| − | production of biofuels, pharmaceuticals, or high value chemicals.
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| − | <br>
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| − | By integrating enzymes or biosynthetic pathways into semi-permeable organelles we
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| − | gain higher concentrations of enzymes and metabolites and provide a basis for the
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| − | ideal operation of specialized enzymes. Furthermore, toxic or unstable intermediates
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| − | can be sustained and naturally incompatible reactions can take place
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| − | simultaneously.
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| − | <br>
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| − | We have chosen <span class="label">yeast peroxisomes</span> as our chassis for designing this synthetic organelle, which are very resistant, have a useful import mechanism and are expendable under optimal conditions.
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| − | </p>
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| − | </section>
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| − | <h2>Accordion</h2>
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| − | <button class="accordion">Section 2</button>
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| − | <button class="accordion">Section 3</button>
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| − | <h3>Callout</h3>
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| − | <td>Content Goes Here</td>
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| − | <td>This is longer content Donec id elit non mi porta gravida at eget metus.</td>
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| − | <p>It has an easy to override visual style, and is appropriately subdued.</p>
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| − | <img src="http://placehold.it/350x150">
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| − | <p>It has an easy to override visual style, and is appropriately subdued.</p>
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