Team:Delaware/Description
Description
The gut microbiome is an exciting field of research that has increased exponentially across the past few years. Many studies have found a correlation between imbalances in the gut microbiome and disease states, such as Autism Spectrum Disorder (One such research project at the University of Delaware). To simply ask if altering the gut microbiome can alter or affect a disease state in any way, methods are required for targeted microbiome manipulations that allow researchers or clinicians to modulate the populations of specific microbes within a microbiome. The human gut microbiome is home to what is estimated to be near 1000 microbial species. The goal of our project is to take a genetic engineering approach in vitro to develop methods towards gut microbiome therapeutics that can be more targeted than broad-spectrum antibiotics.
