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| − | <h1>Preliminary Project Description </h1>
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| − | <p>Organisms engineered by synthetic biologists have the potential to deliver solutions to a wide range of problems. However, they must be implemented in responsible and controlled ways.
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| − | For example, last year the Kingsborough team focused on engineering E. coli to degrade nitrogenous waste in sewage more effectively. However, we found that E. coli can survive in local waterways, which is the ultimate destination for wastewater after treatment. To combat escape of modified E. coli from the treatment plant, we are focused this year on improving and characterizing a control element, commonly referred to as a 'Kill switch'.
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| − | We will focus on development of a light-inducible kill switch, since the bacteria will not be exposed to significant amounts of light within the sewage treatment plant. Other teams have proposed and modeled such switches, but few have successfully built, implemented, and characterized such devices. </p>
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| − | <h1>Interested in a Collaboration? </h1>
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| − | <p>We are eager to collaborate with any teams that are willing, especially if they are local to the New York area. This could range from a discussion of synthetic biology and public perception to collaborating on laboratory work and results - we would be especially grateful for any teams that would like to implement or test the "kill-switch" devices that we engineer!
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