Difference between revisions of "Team:Newcastle"

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Biosensor networks are ordinarily encoded for on a single plasmid.
 
Biosensor networks are ordinarily encoded for on a single plasmid.
 
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<img src="https://static.igem.org/mediawiki/2017/b/bd/T--Newcastle--BB_framework_backbone.png"/>
 
<img src="https://static.igem.org/mediawiki/2017/b/bd/T--Newcastle--BB_framework_backbone.png"/>
  
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By separating biosensor networks into modules, variants of these modules can be more easily varied and developed.
 
By separating biosensor networks into modules, variants of these modules can be more easily varied and developed.
 
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Each module of a biosensor could also be encoded by a separate cell, with quorum sensing molecules (e.g. acyl homoserine lactones - AHLs) enabiling communication between modules. This separation would reduce the 'load' taken on by each cell, as they would only need to express a module instead of the entire biosensor network. It would also enable biosensor variants to be made and tested without the need for lots of long and tedious genetic cloning.
 
Each module of a biosensor could also be encoded by a separate cell, with quorum sensing molecules (e.g. acyl homoserine lactones - AHLs) enabiling communication between modules. This separation would reduce the 'load' taken on by each cell, as they would only need to express a module instead of the entire biosensor network. It would also enable biosensor variants to be made and tested without the need for lots of long and tedious genetic cloning.
 
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We have created the 'Sensynova Biosensor Development Framework' (above), which separates out biosensors into three modules; a detector, a processor, and a reporter. We have also included an optional 'adapter' module. To learn more about our framework, go to our <a href="">project description</a> page!
 
We have created the 'Sensynova Biosensor Development Framework' (above), which separates out biosensors into three modules; a detector, a processor, and a reporter. We have also included an optional 'adapter' module. To learn more about our framework, go to our <a href="">project description</a> page!
  

Revision as of 20:01, 26 October 2017

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Newcastle iGEM 2017 Team Presents...


Background Image: Diffusion of C4-HSL (produced by one cell type, detected by another which produces sfGFP in the presence of C4-HSL)

Welcome to
A New Era of

Biosensor networks are ordinarily encoded for on a single plasmid.

By separating biosensor networks into modules, variants of these modules can be more easily varied and developed.

Each module of a biosensor could also be encoded by a separate cell, with quorum sensing molecules (e.g. acyl homoserine lactones - AHLs) enabiling communication between modules. This separation would reduce the 'load' taken on by each cell, as they would only need to express a module instead of the entire biosensor network. It would also enable biosensor variants to be made and tested without the need for lots of long and tedious genetic cloning.

We have created the 'Sensynova Biosensor Development Framework' (above), which separates out biosensors into three modules; a detector, a processor, and a reporter. We have also included an optional 'adapter' module. To learn more about our framework, go to our project description page!


Email Address: newcastle.igem@outlook.com
Twitter: https://twitter.com/newcastle_igem