Difference between revisions of "Team:Newcastle"
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| − | Biosensor networks are ordinarily encoded for on a single plasmid. | + | Biosensor networks are ordinarily encoded for on a single plasmid within a chassis. However, this can create stress on the host organism as they have to express the entire network, and the biosensor can not be easily modified. |
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<img src="https://static.igem.org/mediawiki/2017/b/bd/T--Newcastle--BB_framework_backbone.png"/> | <img src="https://static.igem.org/mediawiki/2017/b/bd/T--Newcastle--BB_framework_backbone.png"/> | ||
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| − | + | To alleviate these problems, we propose that biosensor networks are split into three modules; a detector, a processor, and a reporter. | |
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| − | + | With this in mind, we have created the 'Sensynova Biosensor Development Framework'. This framework separates each module into individual cells which communicate via quorum sensing molecules. This separation would reduce the 'load' taken on by each cell, as they would only need to express a module instead of the entire biosensor network. It would also enable biosensor variants to be made and tested without the need for lots of long and tedious genetic cloning. | |
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| − | <img src=""/> | + | <img src="https://static.igem.org/mediawiki/2017/0/03/T--Newcastle--BB_framework_framework.png"/> |
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| − | We have created the 'Sensynova Biosensor Development Framework' | + | We have created the 'Sensynova Biosensor Development Framework', which separates out biosensors into three modules; a detector, a processor, and a reporter. We have also included an optional 'adapter' module. To learn more about our framework, go to our <a href="">project description</a> page! |
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Revision as of 20:24, 26 October 2017
Newcastle iGEM 2017 Team Presents...
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Welcome toA New Era of
Biosensor networks are ordinarily encoded for on a single plasmid within a chassis. However, this can create stress on the host organism as they have to express the entire network, and the biosensor can not be easily modified. 
To alleviate these problems, we propose that biosensor networks are split into three modules; a detector, a processor, and a reporter. 
With this in mind, we have created the 'Sensynova Biosensor Development Framework'. This framework separates each module into individual cells which communicate via quorum sensing molecules. This separation would reduce the 'load' taken on by each cell, as they would only need to express a module instead of the entire biosensor network. It would also enable biosensor variants to be made and tested without the need for lots of long and tedious genetic cloning. 
We have created the 'Sensynova Biosensor Development Framework', which separates out biosensors into three modules; a detector, a processor, and a reporter. We have also included an optional 'adapter' module. To learn more about our framework, go to our project description page! |
