Team:Newcastle
Newcastle iGEM 2017 Team Presents...
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Welcome toA New Era of
Biosensor genetic networks are typically encoded on a single plasmid within a single chassis. However, this can create stress on the host organism as they have to express the entire network, and the biosensor can not be easily modified. 
To alleviate these problems, we propose that biosensor networks are split into three modules; a detector, a processor, and a reporter. 
With this in mind, we have created the 'Sensynova Biosensor Development Framework'. This framework separates each module into individual cells which communicate via quorum sensing molecules. This separation would reduce the 'load' taken on by each cell, as they would only need to express a module instead of the entire biosensor network. It would also enable biosensor variants to be made and tested without the need for lots of long and tedious genetic cloning. 
We have also included an optional 'adapter' module. To learn more about our framework, go to our project description page! |
