Difference between revisions of "Team:Toronto/Drylab"

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<h2 class="text-yellow">Ordinary Differential Equations</h2>
 
<h2 class="text-yellow">Ordinary Differential Equations</h2>
<p>Capturing the dynamics of construct developed in the wet lab to further characterize its behaviour with Ordinary Differential Equations (ODE’s)</p>
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<p>Capturing the dynamics of construct developed in the wet lab to further characterize its behaviour with Ordinary Differential Equations (ODEs).</p>
 
<a href="https://2017.igem.org/Team:Toronto/ODE"><button class="btn-primary yellow">More Info</button></a>
 
<a href="https://2017.igem.org/Team:Toronto/ODE"><button class="btn-primary yellow">More Info</button></a>
 
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<h2>Analysis</h2>
 
<h2>Analysis</h2>
<p>Using Mathworks Simulink package we ran multiple simulations to obtain a clear picture of how our system behaves. Then with R we leverage the data from wetlab  to derive key parameters.</p>
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<p>Using Mathworks Simulink package, we ran multiple simulations to obtain a clear picture of how our system behaves. Then with R we leverage the data from Wet Lab to derive key parameters.</p>
 
<a href="https://2017.igem.org/Team:Toronto/Analysis"><button class="btn-primary yellow">More Info</button></a>
 
<a href="https://2017.igem.org/Team:Toronto/Analysis"><button class="btn-primary yellow">More Info</button></a>
 
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Revision as of 20:31, 23 November 2017

Dry Lab

Ordinary Differential Equations

Capturing the dynamics of construct developed in the wet lab to further characterize its behaviour with Ordinary Differential Equations (ODEs).

Analysis

Using Mathworks Simulink package, we ran multiple simulations to obtain a clear picture of how our system behaves. Then with R we leverage the data from Wet Lab to derive key parameters.

Modelling

We modeled LacILOV’s protein structure, which exposed undesirable interactions between the linker region and the functional domains. We then mutated the linker computationally to devise substitutions to improve LacILOV’s sensitivity to light.