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How make a homosexual fruit fly It is reported that pharmacological manipulation of dopamine could alter their sexual behavior. Increased dopamine level may lead to male-male courtship in Drosophila. (Increased Dopamine Level Enhances Male–Male Courtship in Drosophila. Liu Tong, et al. The journal of Neuroscience). Here we use the modified Gal4-UAS system, which is a commonly used heterotopic expression system in fruit fly genetics, to realize the ubiquitous expression of Dopamine in fruit fly. According to news reports, as of May 24, 2017, there have been 22 countries in the world (Scotland in the UK) and parts of the country and overseas territories have legislated to recognize gay marriage. Same-sex human rights are increasing rapidly in the whole world. However, China hasn’t recognized same-sex marriage yet. Many homosexuals are under great pressure from their parents and the society. We want to make some change and show that homosexuality shouldn’t be unfairly demonized.