Team:Manchester/Resources/JS:NGL

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e=this.prevPosition.x-this.position.x,i=this.prevPosition.y-this.position.y;this.signals.moved.dispatch(e,i),this.pressed&&this.signals.dragged.dispatch(e,i)},Xf.prototype._onMousedown=function(t){t.target===this.domElement&&(t.preventDefault(),this._setKeys(t),this.moving=!1,this.hovering=!1,this.down.set(t.clientX,t.clientY),this.position.set(t.clientX,t.clientY),this.which=t.which,this.buttons=Xo(t),this.pressed=!0,this._setCanvasPosition(t))},Xf.prototype._onMouseup=function(t){t.target===this.domElement&&t.preventDefault(),this._setKeys(t);var e=this.canvasPosition;this.signals.clicked.dispatch(e.x,e.y),this.which=void 0,this.buttons=void 0,this.pressed=void 0},Xf.prototype._onContextmenu=function(t){t.target===this.domElement&&t.preventDefault()},Xf.prototype._onTouchstart=function(t){if(t.target===this.domElement)switch(t.preventDefault(),this.pressed=!0,t.touches.length){case 1:this.moving=!1,this.hovering=!1,this.down.set(t.touches[0].pageX,t.touches[0].pageY),this.position.set(t.touches[0].pageX,t.touches[0].pageY),this._setCanvasPosition(t.touches[0]);break;case 2:this.down.set((t.touches[0].pageX+t.touches[1].pageX)/2,(t.touches[0].pageY+t.touches[1].pageY)/2),this.position.set((t.touches[0].pageX+t.touches[1].pageX)/2,(t.touches[0].pageY+t.touches[1].pageY)/2),this.lastTouchDistance=Wo(t)}},Xf.prototype._onTouchend=function(t){t.target===this.domElement&&t.preventDefault(),this.pressed=!1},Xf.prototype._onTouchmove=function(t){switch(t.target===this.domElement?(t.preventDefault(),this.overElement=!0):this.overElement=!1,t.touches.length){case 1:this._setKeys(t),this.which=void 0,this.buttons=void 0,this.moving=!0,this.hovering=!1,this.lastMoved=performance.now(),this.prevPosition.copy(this.position),this.position.set(t.touches[0].pageX,t.touches[0].pageY),this._setCanvasPosition(t.touches[0]);var e=this.prevPosition.x-this.position.x,i=this.prevPosition.y-this.position.y;this.signals.moved.dispatch(e,i),this.pressed&&this.signals.dragged.dispatch(e,i);break;case 2:this.which=3,this.buttons=2;var r=Wo(t),n=r-this.lastTouchDistance;if(this.lastTouchDistance=r,Math.abs(n)>1)this.signals.scrolled.dispatch(n/2);else{this.prevPosition.copy(this.position),this.position.set((t.touches[0].pageX+t.touches[1].pageX)/2,(t.touches[0].pageY+t.touches[1].pageY)/2);var o=this.prevPosition.x-this.position.x,a=this.prevPosition.y-this.position.y;this.signals.moved.dispatch(o,a),this.pressed&&this.signals.dragged.dispatch(o,a)}}},Xf.prototype._distance=function(){return this.position.distanceTo(this.down)},Xf.prototype._setCanvasPosition=function(t){var e,i,r=this.domElement.getBoundingClientRect();"offsetX"in t&&"offsetY"in t?(e=t.offsetX,i=t.offsetY):(e=t.clientX-r.left,i=t.clientY-r.top),this.canvasPosition.set(e,r.height-i)},Xf.prototype._setKeys=function(t){this.altKey=t.altKey,this.ctrlKey=t.ctrlKey,this.metaKey=t.metaKey,this.shiftKey=t.shiftKey},Xf.prototype.dispose=function(){document.removeEventListener("mousewheel",this._onMousewheel),document.removeEventListener("wheel",this._onMousewheel),document.removeEventListener("MozMousePixelScroll",this._onMousewheel),document.removeEventListener("mousemove",this._onMousemove),document.removeEventListener("mousedown",this._onMousedown),document.removeEventListener("mouseup",this._onMouseup),document.removeEventListener("contextmenu",this._onContextmenu),document.removeEventListener("touchstart",this._onTouchstart),document.removeEventListener("touchend",this._onTouchend),document.removeEventListener("touchmove",this._onTouchmove)},Object.defineProperties(Xf.prototype,qf);var Yf=new v,Zf=new v,Kf=new v,Qf=new g,Jf=new m,tm=new v,em=new g,im=function(t,e){var i=e||{};this.rotateSpeed=dn(i.rotateSpeed,2),this.zoomSpeed=dn(i.zoomSpeed,1.2),this.panSpeed=dn(i.panSpeed,1),this.stage=t,this.viewer=t.viewer,this.mouse=t.mouseObserver,this.controls=t.viewerControls},rm={component:{}};rm.component.get=function(){return this.stage.transformComponent},im.prototype._setPanVector=function(t,e){var i,r=this.viewer.camera;if("OrthographicCamera"===r.type)i=1/r.zoom;else{var n=Gn(r.fov);i=-2*r.position.z*Math.tan(n/2)/this.viewer.height}em.set(t,e,0),em.multiplyScalar(this.panSpeed*i)},im.prototype._getRotateXY=function(t,e){return[this.rotateSpeed*-t*.01,this.rotateSpeed*e*.01]},im.prototype.zoom=function(t){this.controls.zoom(this.zoomSpeed*t*.02)},im.prototype.pan=function(t,e){this._setPanVector(t,e),tm.getInverse(this.viewer.rotationGroup.matrix),em.applyMatrix4(tm),this.controls.translate(em)},im.prototype.panComponent=function(t,e){this.component&&(this._setPanVector(t,e),tm.extractRotation(this.component.transform),tm.premultiply(this.viewer.rotationGroup.matrix),tm.getInverse(tm),em.applyMatrix4(tm),this.component.position.add(em),this.component.updateMatrix())},im.prototype.rotate=function(t,e){var i=this._getRotateXY(t,e),r=i[0],n=i[1];Yf.makeRotationX(n),Zf.makeRotationY(r),Yf.multiply(Zf),this.controls.applyMatrix(Yf)},im.prototype.rotateComponent=function(t,e){if(this.component){var i=this._getRotateXY(t,e),r=i[0],n=i[1];Kf.extractRotation(this.component.transform),Kf.premultiply(this.viewer.rotationGroup.matrix),Kf.getInverse(Kf),Qf.set(1,0,0),Qf.applyMatrix4(Kf),Yf.makeRotationAxis(Qf,n),Qf.set(0,1,0),Qf.applyMatrix4(Kf),Zf.makeRotationAxis(Qf,r),Yf.multiply(Zf),Jf.setFromRotationMatrix(Yf),this.component.quaternion.premultiply(Jf),this.component.updateMatrix()}},Object.defineProperties(im.prototype,rm);var nm=function(t,e){this.pid=t.pid,this.picker=t.picker,this.instance=t.instance,this.stage=e,this.controls=e.viewerControls,this.mouse=e.mouseObserver},om={type:{},altKey:{},ctrlKey:{},metaKey:{},shiftKey:{},canvasPosition:{},component:{},object:{},position:{},closestBondAtom:{},arrow:{},atom:{},axes:{},bond:{},cone:{},clash:{},contact:{},cylinder:{},distance:{},ellipsoid:{},mesh:{},slice:{},sphere:{},surface:{},unitcell:{},unknown:{},volume:{}};om.type.get=function(){return this.picker.type},om.altKey.get=function(){return this.mouse.altKey},om.ctrlKey.get=function(){return this.mouse.ctrlKey},om.metaKey.get=function(){return this.mouse.metaKey},om.shiftKey.get=function(){return this.mouse.shiftKey},om.canvasPosition.get=function(){return this.mouse.canvasPosition},om.component.get=function(){return this.stage.getComponentsByObject(this.picker.data).list[0]},om.object.get=function(){return this.picker.getObject(this.pid)},om.position.get=function(){return this.picker.getPosition(this.pid,this.instance,this.component)},om.closestBondAtom.get=function(){if("bond"===this.type){var t=this.bond,e=this.controls;return qo(this.canvasPosition,e.getPositionOnCanvas(t.atom1),e.getPositionOnCanvas(t.atom2))?t.atom1:t.atom2}},om.arrow.get=function(){return this._objectIfType("arrow")},om.atom.get=function(){return this._objectIfType("atom")},om.axes.get=function(){return this._objectIfType("axes")},om.bond.get=function(){return this._objectIfType("bond")},om.cone.get=function(){return this._objectIfType("cone")},om.clash.get=function(){return this._objectIfType("clash")},om.contact.get=function(){return this._objectIfType("contact")},om.cylinder.get=function(){return this._objectIfType("cylinder")},om.distance.get=function(){return this._objectIfType("distance")},om.ellipsoid.get=function(){return this._objectIfType("ellipsoid")},om.mesh.get=function(){return this._objectIfType("mesh")},om.slice.get=function(){return this._objectIfType("slice")},om.sphere.get=function(){return this._objectIfType("sphere")},om.surface.get=function(){return this._objectIfType("surface")},om.unitcell.get=function(){return this._objectIfType("unitcell")},om.unknown.get=function(){return this._objectIfType("unknown")},om.volume.get=function(){return this._objectIfType("volume")},nm.prototype._objectIfType=function(t){return this.type===t?this.object:void 0},nm.prototype.getLabel=function(){var t="nothing";return this.arrow?t="arrow: "+(this.arrow.name||this.pid)+" ("+this.arrow.shape.name+")":this.atom?t="atom: "+this.atom.qualifiedName()+" ("+this.atom.structure.name+")":this.axes?t="axes":this.bond?t="bond: "+this.bond.atom1.qualifiedName()+" - "+this.bond.atom2.qualifiedName()+" ("+this.bond.structure.name+")":this.cone?t="cone: "+(this.cone.name||this.pid)+" ("+this.cone.shape.name+")":this.clash?t="clash: "+this.clash.clash.sele1+" - "+this.clash.clash.sele2:this.contact?t="contact: "+this.contact.atom1.qualifiedName()+" - "+this.contact.atom2.qualifiedName()+" ("+this.contact.structure.name+")":this.cylinder?t="cylinder: "+(this.cylinder.name||this.pid)+" ("+this.cylinder.shape.name+")":this.distance?t="distance: "+this.distance.atom1.qualifiedName()+" - "+this.distance.atom2.qualifiedName()+" ("+this.distance.structure.name+")":this.ellipsoid?t="ellipsoid: "+(this.ellipsoid.name||this.pid)+" ("+this.ellipsoid.shape.name+")":this.mesh?t="mesh: "+(this.mesh.name||this.mesh.serial)+" ("+this.mesh.shape.name+")":this.slice?t="slice: "+this.slice.value.toPrecision(3)+" ("+this.slice.volume.name+")":this.sphere?t="sphere: "+(this.sphere.name||this.pid)+" ("+this.sphere.shape.name+")":this.surface?t="surface: "+this.surface.surface.name:this.unitcell?t="unitcell: "+this.unitcell.unitcell.spacegroup+" ("+this.unitcell.structure.name+")":this.unknown?t="unknown":this.volume&&(t="volume: "+this.volume.value.toPrecision(3)+" ("+this.volume.volume.name+")"),t},Object.defineProperties(nm.prototype,om);var am=function(t){this.stage=t,this.viewer=t.viewer};am.prototype.pick=function(t,e){var i=this.viewer.pick(t,e);if(i.picker&&"ignore"!==i.picker.type&&void 0!==i.pid){var r=i.picker.array;if(!(r&&i.pid>=r.length))return new nm(i,this.stage);console.error("pid >= picker.array.length")}};var sm=new m,cm=new g,um=new g,hm=new g,lm=new g,pm=new v,dm=new g,fm=new v,mm=function(t){this.stage=t,this.viewer=t.viewer,this.signals={changed:new io}},gm={position:{},rotation:{}};gm.position.get=function(){return this.viewer.translationGroup.position},gm.rotation.get=function(){return this.viewer.rotationGroup.quaternion},mm.prototype.changed=function(){this.viewer.requestRender(),this.signals.changed.dispatch()},mm.prototype.getPositionOnCanvas=function(t,e){var i=Rn(e),r=this.viewer;return hm.copy(t).add(r.translationGroup.position).applyMatrix4(r.rotationGroup.matrix).project(r.camera),i.set((hm.x+1)*r.width/2,(hm.y+1)*r.height/2)},mm.prototype.getOrientation=function(t){var e=Dn(t);e.copy(this.viewer.rotationGroup.matrix);var i=-this.viewer.camera.position.z;return e.scale(lm.set(i,i,i)),e.setPosition(this.viewer.translationGroup.position),e},mm.prototype.orient=function(t){Dn(t).decompose(cm,sm,um);var e=this.viewer;e.rotationGroup.setRotationFromQuaternion(sm),e.translationGroup.position.copy(cm),e.camera.position.z=-um.z,e.updateZoom(),this.changed()},mm.prototype.translate=function(t){this.viewer.translationGroup.position.add(On(t)),this.changed()},mm.prototype.center=function(t){this.viewer.translationGroup.position.copy(On(t)).negate(),this.changed()},mm.prototype.zoom=function(t){this.distance(this.viewer.camera.position.z*(1-t))},mm.prototype.distance=function(t){this.viewer.camera.position.z=t,this.viewer.updateZoom(),this.changed()},mm.prototype.spin=function(t,e){pm.getInverse(this.viewer.rotationGroup.matrix),dm.copy(On(t)).applyMatrix4(pm),this.viewer.rotationGroup.rotateOnAxis(dm,e),this.changed()},mm.prototype.rotate=function(t){this.viewer.rotationGroup.setRotationFromQuaternion(Nn(t)),this.changed()},mm.prototype.align=function(t){fm.getInverse(Dn(t)),this.viewer.rotationGroup.setRotationFromMatrix(fm),this.changed()},mm.prototype.applyMatrix=function(t){this.viewer.rotationGroup.applyMatrix(Dn(t)),this.changed()},Object.defineProperties(mm.prototype,gm);var vm=function(t,e){for(var i=[],r=arguments.length-2;r-- >0;)i[r]=arguments[r+2];this.duration=dn(t,1e3),this.controls=e,this.startTime=performance.now(),this.elapsedTime=0,this._resolveList=[],(n=this)._init.apply(n,i);var n},ym={done:{}};ym.done.get=function(){return 1===this.alpha},vm.prototype._init=function(){},vm.prototype._tick=function(){},vm.prototype.tick=function(t){return this.elapsedTime=t.currentTime-this.startTime,0===this.duration?this.alpha=1:this.alpha=Qn(0,1,this.elapsedTime/this.duration),this._tick(t),this.done&&this._resolveList.forEach(function(t){t()}),this.done},vm.prototype.then=function(t){var e=this;return(this.done?Promise.resolve():new Promise(function(t){e._resolveList.push(t)})).then(t)},Object.defineProperties(vm.prototype,ym);var bm=function(t){function e(e){for(var i=[],r=arguments.length-1;r-- >0;)i[r]=arguments[r+1];t.apply(this,[dn(e,1/0)].concat(i))}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype._init=function(t,e){Array.isArray(t)?this.axis=(new g).fromArray(t):this.axis=dn(t,new g(0,1,0)),this.angle=dn(e,.01)},e.prototype._tick=function(t){this.axis&&this.angle&&this.controls.spin(this.axis,this.angle*t.lastDuration/16)},e}(vm),xm=function(t){function e(e){for(var i=[],r=arguments.length-1;r-- >0;)i[r]=arguments[r+1];t.apply(this,[dn(e,1/0)].concat(i))}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype._init=function(t,e,i){Array.isArray(t)?this.axis=(new g).fromArray(t):this.axis=dn(t,new g(0,1,0)),this.angleStep=dn(e,.01),this.angleEnd=dn(i,.2),this.angleSum=0,this.direction=1},e.prototype._tick=function(t){if(this.axis&&this.angleStep&&this.angleEnd){var e=Qn(0,1,Math.abs(this.angleSum)/this.angleEnd),i=this.angleStep*this.direction*(1.1-e);this.controls.spin(this.axis,i*t.lastDuration/16),this.angleSum+=this.angleStep,this.angleSum>=this.angleEnd&&(this.direction*=-1,this.angleSum=-this.angleEnd)}},e}(vm),_m=function(t){function e(){t.apply(this,arguments)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype._init=function(t,e){this.moveFrom=On(dn(t,new g)),this.moveTo=On(dn(e,new g))},e.prototype._tick=function(){this.controls.position.lerpVectors(this.moveFrom,this.moveTo,this.alpha).negate(),this.controls.changed()},e}(vm),wm=function(t){function e(){t.apply(this,arguments)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype._init=function(t,e){this.zoomFrom=t,this.zoomTo=e},e.prototype._tick=function(){this.controls.distance(Zn(this.zoomFrom,this.zoomTo,this.alpha))},e}(vm),Sm=function(t){function e(){t.apply(this,arguments)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype._init=function(t,e){this.rotateFrom=Nn(t),this.rotateTo=Nn(e),this._currentRotation=new m},e.prototype._tick=function(){this._currentRotation.copy(this.rotateFrom).slerp(this.rotateTo,this.alpha),this.controls.rotate(this._currentRotation)},e}(vm),Am=function(t){function e(){t.apply(this,arguments)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype._init=function(t,e,i){this.valueFrom=t,this.valueTo=e,this.callback=i},e.prototype._tick=function(){this.callback(Zn(this.valueFrom,this.valueTo,this.alpha))},e}(vm),Mm=function(t){this._list=t||[],this._resolveList=[]},Pm={done:{}};Pm.done.get=function(){return this._list.every(function(t){return t.done})},Mm.prototype.then=function(t){var e=this;return(this.done?Promise.resolve():new Promise(function(t){e._resolveList.push(t),e._list.forEach(function(t){t.then(function(){e._resolveList.forEach(function(t){t()}),e._resolveList.length=0})})})).then(t)},Object.defineProperties(Mm.prototype,Pm);var Tm=function(t){this.stage=t,this.viewer=t.viewer,this.controls=t.viewerControls,this.animationList=[],this.finishedList=[]};Tm.prototype.add=function(t){return 0===t.duration?t.tick(this.viewer.stats):this.animationList.push(t),t},Tm.prototype.remove=function(t){var e=this.animationList,i=e.indexOf(t);i>-1&&e.splice(i,1)},Tm.prototype.run=function(t){for(var e=this,i=this.finishedList,r=this.animationList,n=r.length,o=0;o<n;++o){var a=r[o];a.tick(t)&&i.push(a)}var s=i.length;if(s){for(var c=0;c<s;++c)e.remove(i[c]);i.length=0}},Tm.prototype.spin=function(t,e,i){return this.add(new bm(i,this.controls,t,e))},Tm.prototype.rock=function(t,e,i,r){return this.add(new xm(r,this.controls,t,e,i))},Tm.prototype.rotate=function(t,e){var i=this.viewer.rotationGroup.quaternion.clone();return this.add(new Sm(e,this.controls,i,t))},Tm.prototype.move=function(t,e){var i=this.controls.position.clone().negate();return this.add(new _m(e,this.controls,i,t))},Tm.prototype.zoom=function(t,e){var i=this.viewer.camera.position.z;return this.add(new wm(e,this.controls,i,t))},Tm.prototype.zoomMove=function(t,e,i){return new Mm([this.move(t,i),this.zoom(e,i)])},Tm.prototype.orient=function(t,e){var i=new g,r=new m,n=new g;return Dn(t).decompose(i,r,n),new Mm([this.move(i.negate(),e),this.rotate(r,e),this.zoom(-n.x,e)])},Tm.prototype.value=function(t,e,i,r){return this.add(new Am(r,this.controls,t,e,i))},Tm.prototype.spinComponent=function(t,e,i,r){return this.add(new bm(r,t.controls,e,i))},Tm.prototype.rockComponent=function(t,e,i,r,n){return this.add(new xm(n,t.controls,e,i,r))},Tm.prototype.moveComponent=function(t,e,i){var r=t.controls.position.clone().negate();return this.add(new _m(i,t.controls,r,e))},Tm.prototype.clear=function(){this.animationList.length=0},Tm.prototype.dispose=function(){this.clear()};var Em=function(){};Em.zoomScroll=function(t,e){t.trackballControls.zoom(e)},Em.clipNearScroll=function(t,e){var i=t.getParameters();t.setParameters({clipNear:i.clipNear+e/10})},Em.focusScroll=function(t,e){var i=2*t.getParameters().clipNear,r=Math.sign(e)*Jn((100-i)/10,5,.2);t.setFocus(i+r)},Em.isolevelScroll=function(t,e){var i=Math.sign(e)/5;t.eachRepresentation(function(t){if("surface"===t.repr.type){var e=t.getParameters().isolevel;t.setParameters({isolevel:e+i})}},"volume")},Em.panDrag=function(t,e,i){t.trackballControls.pan(e,i)},Em.rotateDrag=function(t,e,i){t.trackballControls.rotate(e,i)},Em.zoomDrag=function(t,e,i){t.trackballControls.zoom((e+i)/-2)},Em.zoomFocusDrag=function(t,e,i){t.trackballControls.zoom((e+i)/-2);var r=t.viewer.camera.position.z;t.setFocus(100-Math.abs(r/8))},Em.panComponentDrag=function(t,e,i){t.trackballControls.panComponent(e,i)},Em.rotateComponentDrag=function(t,e,i){t.trackballControls.rotateComponent(e,i)},Em.movePick=function(t,e){e&&t.animationControls.move(e.position.clone())},Em.tooltipPick=function(t,e){var i=t.tooltip;if(t.getParameters().tooltip&&e){var r=e.mouse.position;i.innerText=e.getLabel(),i.style.bottom=window.innerHeight-r.y+3+"px",i.style.left=r.x+3+"px",i.style.display="block"}else i.style.display="none"};var Cm={default:[["scroll",Em.zoomScroll],["scroll-ctrl",Em.clipNearScroll],["scroll-shift",Em.focusScroll],["scroll-alt",Em.isolevelScroll],["drag-right",Em.panDrag],["drag-left",Em.rotateDrag],["drag-middle",Em.zoomDrag],["drag-left+right",Em.zoomDrag],["drag-ctrl-right",Em.panComponentDrag],["drag-ctrl-left",Em.rotateComponentDrag],["clickPick-middle",Em.movePick],["hoverPick",Em.tooltipPick]],pymol:[["drag-left",Em.rotateDrag],["drag-middle",Em.panDrag],["drag-right",Em.zoomDrag],["drag-shift-right",Em.focusScroll],["clickPick-ctrl+shift-middle",Em.movePick],["hoverPick",Em.tooltipPick]],coot:[["scroll",Em.isolevelScroll],["drag-left",Em.rotateDrag],["drag-middle",Em.panDrag],["drag-ctrl-left",Em.panDrag],["drag-right",Em.zoomFocusDrag],["drag-ctrl-right",Em.focusScroll],["clickPick-middle",Em.movePick],["hoverPick",Em.tooltipPick]]},Im=function(t,e){var i=e||{};this.stage=t,this.mouse=t.mouseObserver,this.actionList=[],this.preset(i.preset||"default")};Im.prototype.run=function(t){for(var e=this,i=[],r=arguments.length-1;r-- >0;)i[r]=arguments[r+1];var n=this.mouse.key||0,o=this.mouse.buttons||0;this.actionList.forEach(function(r){r.type===t&&r.key===n&&r.button===o&&r.callback.apply(r,[e.stage].concat(i))})},Im.prototype.add=function(t,e){var i=Yo(t),r=i[0],n=i[1],o=i[2];this.actionList.push({type:r,key:n,button:o,callback:e})},Im.prototype.remove=function(t,e){var i=t.includes("*"),r=Yo(t),n=r[0],o=r[1],a=r[2],s=this.actionList.filter(function(t){return!((t.type===n||i&&""===n)&&(t.key===o||i&&0===o)&&(t.button===a||i&&0===a)&&(t.callback===e||void 0===e))});this.actionList=s},Im.prototype.preset=function(t){var e=this;this.clear(),(Cm[t]||[]).forEach(function(t){(i=e).add.apply(i,t);var i})},Im.prototype.clear=function(){this.actionList.length=0};var Lm=function(t){this.stage=t,this.mouse=t.mouseObserver,this.controls=t.mouseControls,this.mouse.signals.clicked.add(this._onClick,this),this.mouse.signals.hovered.add(this._onHover,this)};Lm.prototype._onClick=function(t,e){var i=this.stage.pickingControls.pick(t,e);this.stage.signals.clicked.dispatch(i),this.controls.run("clickPick",i)},Lm.prototype._onHover=function(t,e){var i=this.stage.pickingControls.pick(t,e);i&&this.mouse.down.equals(this.mouse.position)&&(this.stage.transformComponent=i.component),this.stage.signals.hovered.dispatch(i),this.controls.run("hoverPick",i)},Lm.prototype.dispose=function(){this.mouse.signals.clicked.remove(this._onClick,this),this.mouse.signals.hovered.remove(this._onHover,this)};var Rm=function(t){this.stage=t,this.mouse=t.mouseObserver,this.controls=t.mouseControls,this.mouse.signals.moved.add(this._onMove,this),this.mouse.signals.scrolled.add(this._onScroll,this),this.mouse.signals.dragged.add(this._onDrag,this),this.mouse.signals.clicked.add(this._onClick,this),this.mouse.signals.hovered.add(this._onHover,this)};Rm.prototype._onMove=function(){this.stage.tooltip.style.display="none"},Rm.prototype._onScroll=function(t){this.controls.run("scroll",t)},Rm.prototype._onDrag=function(t,e){this.controls.run("drag",t,e)},Rm.prototype._onClick=function(t,e){this.controls.run("click",t,e)},Rm.prototype._onHover=function(t,e){this.controls.run("hover",t,e)},Rm.prototype.dispose=function(){this.mouse.signals.moved.remove(this._onMove,this),this.mouse.signals.scrolled.remove(this._onScroll,this),this.mouse.signals.dragged.remove(this._onDrag,this),this.mouse.signals.clicked.remove(this._onClick,this),this.mouse.signals.hovered.remove(this._onHover,this)};var Om=function(t){this.viewer=t.viewer,this.animationControls=t.animationControls,this.viewer.signals.ticked.add(this._onTick,this)};Om.prototype._onTick=function(t){this.animationControls.run(t)},Om.prototype.dispose=function(){this.viewer.signals.ticked.remove(this._onTick,this)};var Dm=function(t,e,i,r){var n=r||{};this.offsetX=dn(n.offsetX,0),this.offsetY=dn(n.offsetY,0),this.visible=dn(n.visible,!0),this.component=t,this.stage=t.stage,this.viewer=this.stage.viewer,this.position=e,this._viewerPosition=new g,this._updateViewerPosition(),this._canvasPosition=new g,this._cameraPosition=new g,this.element=document.createElement("div"),Object.assign(this.element.style,{display:"block",position:"fixed",zIndex:1+(parseInt(this.viewer.container.style.zIndex)||0),pointerEvents:"none",backgroundColor:"rgba( 0, 0, 0, 0.6 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this.visible&&this.component.visible},Dm.prototype.updateVisibility=function(){this.element.style.display=this.getVisibility()?"block":"none"},Dm.prototype._updateViewerPosition=function(){this._viewerPosition.copy(this.position).applyMatrix4(this.component.matrix)},Dm.prototype._update=function(){if(this.getVisibility()){var t=this.element.style,e=this._canvasPosition,i=this._viewerPosition,r=this._clientRect;if(this._cameraPosition.copy(i).add(this.viewer.translationGroup.position).applyMatrix4(this.viewer.rotationGroup.matrix).sub(this.viewer.camera.position),this._cameraPosition.z<0)return void(t.display="none");t.display="block",t.opacity=1-Qn(this.viewer.scene.fog.near,this.viewer.scene.fog.far,this._cameraPosition.length()),this.stage.viewerControls.getPositionOnCanvas(i,e),t.bottom=this.offsetX+e.y+r.height/2+"px",t.left=this.offsetY+e.x-r.width/2+"px"}},Dm.prototype.dispose=function(){this.viewer.container.removeChild(this.element),this.viewer.signals.ticked.remove(this._update,this),this.component.signals.matrixChanged.remove(this._updateViewerPosition,this)};var Nm=new v,km=new g,Bm=new m,Fm=function(t){this.component=t,this.stage=t.stage,this.viewer=t.stage.viewer,this.signals={changed:new io}},zm={position:{},rotation:{}};zm.position.get=function(){return this.component.position},zm.rotation.get=function(){return this.component.quaternion},Fm.prototype.changed=function(){this.component.updateMatrix(),this.viewer.requestRender(),this.signals.changed.dispatch()},Fm.prototype.spin=function(t,e){Nm.getInverse(this.viewer.rotationGroup.matrix),km.copy(On(t)).applyMatrix4(Nm),Nm.extractRotation(this.component.transform),Nm.premultiply(this.viewer.rotationGroup.matrix),Nm.getInverse(Nm),km.copy(On(t)),km.applyMatrix4(Nm),Nm.makeRotationAxis(km,e),Bm.setFromRotationMatrix(Nm),this.component.quaternion.premultiply(Bm),this.changed()},Object.defineProperties(Fm.prototype,zm),sa.__deps=[ca],ua.__deps=[ca,aa];var Um=function(t){this.array=t};Um.prototype.getIndex=function(t){return this.array?this.array[t]:t},Um.prototype.getObject=function(){return{}},Um.prototype._applyTransformations=function(t,e,i){return e&&t.applyMatrix4(e.matrix),i&&t.applyMatrix4(i.matrix),t},Um.prototype._getPosition=function(){return new g},Um.prototype.getPosition=function(t,e,i){return this._applyTransformations(this._getPosition(t),e,i)};var jm=function(t){function e(e){t.call(this),this.shape=e}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={data:{}};return i.data.get=function(){return this.shape},Object.defineProperties(e.prototype,i),e}(Um),Gm=function(t){function e(){t.apply(this,arguments)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={type:{}};return i.type.get=function(){return"cylinder"},e.prototype.getObject=function(t){var e=this.shape;return{shape:e,color:(new tt).fromArray(e.cylinderColor,3*t),radius:e.cylinderRadius[t],position1:(new g).fromArray(e.cylinderPosition1,3*t),position2:(new g).fromArray(e.cylinderPosition2,3*t),name:e.cylinderName[t]}},e.prototype._getPosition=function(t){var e=this.shape,i=(new g).fromArray(e.cylinderPosition1,3*t),r=(new g).fromArray(e.cylinderPosition2,3*t);return i.add(r).multiplyScalar(.5)},Object.defineProperties(e.prototype,i),e}(jm),Vm=function(t){function e(){t.apply(this,arguments)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={type:{}};return i.type.get=function(){return"arrow"},e.prototype.getObject=function(t){var e=this.shape;return{shape:e,position:this._getPosition(t),position1:(new g).fromArray(e.arrowPosition1,3*t),position2:(new g).fromArray(e.arrowPosition2,3*t),color:(new tt).fromArray(e.arrowColor,3*t),radius:e.arrowRadius[t],name:e.arrowName[t]}},e.prototype._getPosition=function(t){var e=this.shape,i=(new g).fromArray(e.arrowPosition1,3*t),r=(new g).fromArray(e.arrowPosition2,3*t);return i.add(r).multiplyScalar(.5)},Object.defineProperties(e.prototype,i),e}(jm),$m=function(t){function e(e,i){t.call(this,e),this.structure=i}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={type:{},data:{}};return i.type.get=function(){return"atom"},i.data.get=function(){return this.structure},e.prototype.getObject=function(t){return this.structure.getAtomProxy(this.getIndex(t))},e.prototype._getPosition=function(t){return(new g).copy(this.getObject(t))},Object.defineProperties(e.prototype,i),e}(Um),Hm=function(t){function e(e){t.call(this),this.axes=e}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={type:{},data:{}};return i.type.get=function(){return"axes"},i.data.get=function(){return this.axes},e.prototype.getObject=function(){return{axes:this.axes}},e.prototype._getPosition=function(){return this.axes.center.clone()},Object.defineProperties(e.prototype,i),e}(Um),Wm=function(t){function e(e,i,r){t.call(this,e),this.structure=i,this.bondStore=r||i.bondStore}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={type:{},data:{}};return i.type.get=function(){return"bond"},i.data.get=function(){return 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0),t.Debug&&cf.timeEnd("GeometrySurface.setGeometry")},jg.prototype.getPosition=function(){return this.position},jg.prototype.getColor=function(t){var e=t||{};e.surface=this;var i=this.size,r=new Float32Array(3*i),n=lf.getScheme(e);if(n.volumeColor||"random"===e.scheme)for(var o=0;o<i;++o)n.volumeColorToArray(o,r,3*o);else if(n.positionColor)for(var a=new g,s=this.position,c=0;c<i;++c){var u=3*c;a.set(s[u],s[u+1],s[u+2]),n.positionColorToArray(a,r,u)}else if(n.atomColor&&this.atomindex)for(var h=e.structure.getAtomProxy(),l=this.atomindex,p=0;p<i;++p)h.index=l[p],n.atomColorToArray(h,r,3*p);else{var d=new tt(e.value);To(i,d.r,d.g,d.b,r)}return r},jg.prototype.getPicking=function(t){return this.atomindex&&t?new $m(this.atomindex,t):new eg(Co(this.size),this)},jg.prototype.getNormal=function(){return this.normal},jg.prototype.getSize=function(t,e){return Po(this.size,t*e)},jg.prototype.getIndex=function(){return this.index},jg.prototype.getFilteredIndex=function(t,e){if(t&&this.atomindex){for(var i=new Kd(t),r=e.getAtomSet(i),n=[],o=this.atomindex,a=this.index,s=a.length,c=this.contour?2:3,u=0,h=0;h<s;h+=c){for(var l=!0,p=0;p<c;p++){var d=o[a[h+p]];if(!r.get(d)){l=!1;break}}if(l)for(var f=0;f<c;f++,u++)n[u]=a[h+f]}return Cn(n,this.position.length/3)}return this.index},jg.prototype.getAtomindex=function(){return this.atomindex},jg.prototype.dispose=function(){},Object.defineProperties(jg.prototype,Gg),Ya.__deps=[Ha,Wa,$a,Jo,ta,ka,Ba],hf.add("surf",function(t,e){var i=t.data.args,r=t.data.params;if(i&&(self.volsurf=new Ya(i[0],i[1],i[2],i[3],i[4])),r){var n=self.volsurf.getSurface(r.isolevel,r.smooth,r.box,r.matrix,r.contour,r.wrap),o=[n.position.buffer,n.index.buffer];n.normal&&o.push(n.normal.buffer),n.atomindex&&o.push(n.atomindex.buffer),e({sd:n,p:r},o)}},[Ya]);var Vg=function(t,e,i,r,n,o,a){this.name=t,this.path=e,this.matrix=new v,this.normalMatrix=new ut,this.inverseMatrix=new v,this.center=new g,this.boundingBox=new st,this.setData(i,r,n,o,a)},$g={type:{},position:{},min:{},max:{},sum:{},mean:{},rms:{}};$g.type.get=function(){return"Volume"},Vg.prototype.setData=function(t,e,i,r,n){this.nx=e||1,this.ny=i||1,this.nz=r||1,this.data=t||new Float32Array(1),this.setAtomindex(n),delete this._position,delete this._min,delete this._max,delete this._mean,delete this._rms,this.worker&&this.worker.terminate()},Vg.prototype.setMatrix=function(t){this.matrix.copy(t);var e=this.boundingBox,i=this.center,r=this.nx-1,n=this.ny-1,o=this.nz-1;e.makeEmpty(),e.expandByPoint(i.set(r,n,o)),e.expandByPoint(i.set(r,n,0)),e.expandByPoint(i.set(r,0,o)),e.expandByPoint(i.set(r,0,0)),e.expandByPoint(i.set(0,n,o)),e.expandByPoint(i.set(0,0,o)),e.expandByPoint(i.set(0,n,0)),e.expandByPoint(i.set(0,0,0)),e.applyMatrix4(this.matrix),e.getCenter(this.center);var a=this.matrix.elements,s=new g(a[0],a[1],a[2]),c=new g(a[4],a[5],a[6]),u=new g(a[8],a[9],a[10]),h=new g,l=this.normalMatrix.elements;h.crossVectors(c,u),l[0]=h.x,l[1]=h.y,l[2]=h.z,h.crossVectors(u,s),l[3]=h.x,l[4]=h.y,l[5]=h.z,h.crossVectors(s,c),l[6]=h.x,l[7]=h.y,l[8]=h.z,this.inverseMatrix.getInverse(this.matrix)},Vg.prototype.setAtomindex=function(t){this.atomindex=t},Vg.prototype.getBox=function(t,e,i){return i||(i=new st),i.set(t,t),i.expandByScalar(e),i.applyMatrix4(this.inverseMatrix),i.min.round(),i.max.round(),i},Vg.prototype._getBox=function(t,e){if(t&&e){this.__box||(this.__box=new st);var i=this.getBox(t,e,this.__box);return[i.min.toArray(),i.max.toArray()]}},Vg.prototype._makeSurface=function(t,e,i){var r=this.name+"@"+e.toPrecision(2),n=new jg(r,"",t);return n.info.isolevel=e,n.info.smooth=i,n.info.volume=this,n},Vg.prototype.getSurface=function(t,e,i,r,n,o){t=isNaN(t)?this.getValueForSigma(2):t,e=dn(e,0),void 0===this.volsurf&&(this.volsurf=new Ya(this.data,this.nx,this.ny,this.nz,this.atomindex));var a=this._getBox(i,r),s=this.volsurf.getSurface(t,e,a,this.matrix.elements,n,o);return this._makeSurface(s,t,e)},Vg.prototype.getSurfaceWorker=function(t,e,i,r,n,o,a){var s=this;if(t=isNaN(t)?this.getValueForSigma(2):t,e=e||0,window.Worker){void 0===this.workerPool&&(this.workerPool=new Ua("surf",2));var c={},u=this.workerPool.getNextWorker();0===u.postCount&&(c.args=[this.data,this.nx,this.ny,this.nz,this.atomindex]),c.params={isolevel:t,smooth:e,box:this._getBox(i,r),matrix:this.matrix.elements,contour:n,wrap:o},u.post(c,void 0,function(t){var e=t.data.sd,i=t.data.p;a(s._makeSurface(e,i.isolevel,i.smooth))},function(c){console.warn("Volume.getSurfaceWorker error - trying without worker",c);var u=s.getSurface(t,e,i,r,n,o);a(u)})}else{var h=this.getSurface(t,e,i,r,n,o);a(h)}},Vg.prototype.getValueForSigma=function(t){return this.mean+dn(t,2)*this.rms},Vg.prototype.getSigmaForValue=function(t){return(dn(t,0)-this.mean)/this.rms},$g.position.get=function(){if(!this._position){for(var t=this.nz,e=this.ny,i=this.nx,r=new Float32Array(i*e*t*3),n=0,o=0;o<t;++o)for(var a=0;a<e;++a)for(var s=0;s<i;++s)r[n+0]=s,r[n+1]=a,r[n+2]=o,n+=3;Jo(this.matrix.elements,r),this._position=r}return this._position},Vg.prototype.getDataAtomindex=function(){return this.atomindex},Vg.prototype.getDataPosition=function(){return this.position},Vg.prototype.getDataColor=function(t){var e=t||{};e.volume=this,e.scale=e.scale||"Spectral",e.domain=e.domain||[this.min,this.max];for(var i=lf.getScheme(e),r=this.position.length/3,n=new Float32Array(3*r),o=0;o<r;++o)i.volumeColorToArray(o,n,3*o);return n},Vg.prototype.getDataPicking=function(){var t=Co(this.position.length/3);return new rg(t,this)},Vg.prototype.getDataSize=function(t,e){var i,r=this.data,n=this.position.length/3;switch(t){case"value":i=new Float32Array(r);break;case"abs-value":i=new Float32Array(r);for(var o=0;o<n;++o)i[o]=Math.abs(i[o]);break;case"value-min":i=new Float32Array(r);for(var a=this.min,s=0;s<n;++s)i[s]-=a;break;case"deviation":i=new Float32Array(r);break;default:i=Po(n,t)}if(1!==e)for(var c=0;c<n;++c)i[c]*=e;return i},$g.min.get=function(){return void 0===this._min&&(this._min=ko(this.data)),this._min},$g.max.get=function(){return void 0===this._max&&(this._max=No(this.data)),this._max},$g.sum.get=function(){return void 0===this._sum&&(this._sum=Bo(this.data)),this._sum},$g.mean.get=function(){return void 0===this._mean&&(this._mean=Fo(this.data)),this._mean},$g.rms.get=function(){return void 0===this._rms&&(this._rms=zo(this.data)),this._rms},Vg.prototype.clone=function(){var t=new Vg(this.name,this.path,this.data,this.nx,this.ny,this.nz,this.atomindex);return t.matrix.copy(this.matrix),t.header=Object.assign({},this.header),t},Vg.prototype.dispose=function(){this.workerPool&&this.workerPool.terminate()},Object.defineProperties(Vg.prototype,$g);var Hg=function(t,e,i,r){this.volume=t,this.setFilter(e,i,r)},Wg={header:{},matrix:{},normalMatrix:{},inverseMatrix:{},center:{},boundingBox:{},min:{},max:{},mean:{},rms:{}};Wg.header.get=function(){return this.volume.header},Wg.matrix.get=function(){return this.volume.matrix},Wg.normalMatrix.get=function(){return this.volume.normalMatrix},Wg.inverseMatrix.get=function(){return this.volume.inverseMatrix},Wg.center.get=function(){return this.volume.center},Wg.boundingBox.get=function(){return this.volume.boundingBox},Wg.min.get=function(){return this.volume.min},Wg.max.get=function(){return this.volume.max},Wg.mean.get=function(){return this.volume.mean},Wg.rms.get=function(){return this.volume.rms},Hg.prototype._getFilterHash=function(t,e,i){return JSON.stringify([t,e,i])},Hg.prototype.setFilter=function(t,e,i){isNaN(t)&&this.header&&(t=this.header.DMEAN+2*this.header.ARMS),t=void 0===t||isNaN(t)?-1/0:t,e=dn(e,1/0),i=dn(i,!1);var r=this.volume.data,n=this.volume.position,o=this.volume.atomindex,a=this._getFilterHash(t,e,i);if(a!==this._filterHash){if(t===-1/0&&e===1/0)this.data=r,this.position=n,this.atomindex=o;else{var s=r.length;this._dataBuffer||(this._dataBuffer=new ArrayBuffer(4*s),this._positionBuffer=new ArrayBuffer(3*s*4),o&&(this._atomindexBuffer=new ArrayBuffer(4*s)));var c,u=new Float32Array(this._dataBuffer),h=new Float32Array(this._positionBuffer);o&&(c=new Uint32Array(this._atomindexBuffer));for(var l=0,p=0;p<s;++p){var d=3*p,f=r[p];if(!i&&f>=t&&f<=e||i&&(f<t||f>e)){var m=3*l;u[l]=f,h[m+0]=n[d+0],h[m+1]=n[d+1],h[m+2]=n[d+2],o&&(c[l]=o[p]),l+=1}}this.data=new Float32Array(this._dataBuffer,0,l),this.position=new Float32Array(this._positionBuffer,0,3*l),o&&(this.atomindex=new Float32Array(this._atomindexBuffer,0,l))}this._filterHash=a}},Object.defineProperties(Hg.prototype,Wg),Hg.prototype.getValueForSigma=Vg.prototype.getValueForSigma,Hg.prototype.getSigmaForValue=Vg.prototype.getSigmaForValue,Hg.prototype.getDataAtomindex=Vg.prototype.getDataAtomindex,Hg.prototype.getDataPosition=Vg.prototype.getDataPosition,Hg.prototype.getDataColor=Vg.prototype.getDataColor,Hg.prototype.getDataPicking=Vg.prototype.getDataPicking,Hg.prototype.getDataSize=Vg.prototype.getDataSize;var Xg=function(e,i){t.Debug&&cf.time("BondHash init");for(var r=e.count,n=e.atomIndex1,o=e.atomIndex2,a=new Uint8Array(i),s=new Int32Array(i),c=0;c<r;++c)a[n[c]]+=1,a[o[c]]+=1;for(var u=1;u<i;++u)s[u]+=s[u-1]+a[u-1];for(var h=2*r,l=new Int32Array(h),p=0;p<h;++p)l[p]=-1;for(var d=0;d<r;++d){for(var f=n[d],m=o[d],g=s[f];-1!==l[g];)g+=1;l[g]=d;for(var v=s[m];-1!==l[v];)v+=1;l[v]=d}t.Debug&&cf.timeEnd("BondHash init"),this.countArray=a,this.offsetArray=s,this.indexArray=l},qg=function(t){Number.isInteger(t)?this.init(t):this.init(0)};qg.prototype.init=function(t){var e=this;this.length=t,this.count=0;for(var i=0,r=this.__fields.length;i<r;++i){var n=e.__fields[i][0],o=e.__fields[i][1],a=e.__fields[i][2],s=e.length*o;e[n]=En(a,s)}},qg.prototype.resize=function(t){var e=this;this.length=Math.round(t||0),this.count=Math.min(this.count,this.length);for(var i=0,r=this.__fields.length;i<r;++i){var n=e.__fields[i][0],o=e.__fields[i][1],a=e.length*o,s=new e[n].constructor(a);e[n].length>a?s.set(e[n].subarray(0,a)):s.set(e[n]),e[n]=s}},qg.prototype.growIfFull=function(){if(this.count>=this.length){var t=Math.round(1.5*this.length);this.resize(Math.max(256,t))}},qg.prototype.copyFrom=function(t,e,i,r){for(var n=this,o=0,a=this.__fields.length;o<a;++o)for(var s=n.__fields[o][0],c=n.__fields[o][1],u=n[s],h=t[s],l=0;l<r;++l)for(var p=c*(e+l),d=c*(i+l),f=0;f<c;++f)u[p+f]=h[d+f]},qg.prototype.copyWithin=function(t,e,i){for(var r=this,n=0,o=this.__fields.length;n<o;++n)for(var a=r.__fields[n][0],s=r.__fields[n][1],c=r[a],u=0;u<i;++u)for(var h=s*(t+u),l=s*(e+u),p=0;p<s;++p)c[h+p]=c[l+p]},qg.prototype.sort=function(t){function e(t,e){t!==e&&(n.copyFrom(r,0,t,1),r.copyWithin(t,e,1),r.copyFrom(n,e,0,1))}function i(r,n){if(r<n){var o=Math.floor((r+n)/2),a=r,s=n;do{for(;t(a,o)<0;)a+=1;for(;t(s,o)>0;)s-=1;a<=s&&(a===o?o=s:s===o&&(o=a),e(a,s),a+=1,s-=1)}while(a<=s);i(r,s),i(a,n)}}cf.time("Store.sort");var r=this,n=new this.constructor(1);i(0,this.count-1),cf.timeEnd("Store.sort")},qg.prototype.clear=function(){this.count=0},qg.prototype.dispose=function(){var t=this;delete this.length,delete this.count;for(var e=0,i=this.__fields.length;e<i;++e)delete t[t.__fields[e][0]]};var Yg=function(t){function e(){t.apply(this,arguments)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={__fields:{}};return i.__fields.get=function(){return[["atomIndex1",1,"int32"],["atomIndex2",1,"int32"],["bondOrder",1,"int8"]]},e.prototype.addBond=function(t,e,i){this.growIfFull();var r=this.count,n=t.index,o=e.index;n<o?(this.atomIndex1[r]=n,this.atomIndex2[r]=o):(this.atomIndex2[r]=n,this.atomIndex1[r]=o),i&&(this.bondOrder[r]=i),this.count+=1},e.prototype.addBondIfConnected=function(t,e,i){return!!t.connectedTo(e)&&(this.addBond(t,e,i),!0)},Object.defineProperties(e.prototype,i),e}(qg),Zg=function(t){function e(){t.apply(this,arguments)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={__fields:{}};return i.__fields.get=function(){return[["residueIndex",1,"uint32"],["atomTypeId",1,"uint16"],["x",1,"float32"],["y",1,"float32"],["z",1,"float32"],["serial",1,"int32"],["bfactor",1,"float32"],["altloc",1,"uint8"],["occupancy",1,"float32"]]},e.prototype.setAltloc=function(t,e){this.altloc[t]=e.charCodeAt(0)},e.prototype.getAltloc=function(t){var e=this.altloc[t];return e?String.fromCharCode(e):""},Object.defineProperties(e.prototype,i),e}(qg),Kg=function(t){function e(){t.apply(this,arguments)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={__fields:{}};return i.__fields.get=function(){return[["chainIndex",1,"uint32"],["atomOffset",1,"uint32"],["atomCount",1,"uint16"],["residueTypeId",1,"uint16"],["resno",1,"int32"],["sstruc",1,"uint8"],["inscode",1,"uint8"]]},e.prototype.setSstruc=function(t,e){this.sstruc[t]=e.charCodeAt(0)},e.prototype.getSstruc=function(t){var e=this.sstruc[t];return e?String.fromCharCode(e):""},e.prototype.setInscode=function(t,e){this.inscode[t]=e.charCodeAt(0)},e.prototype.getInscode=function(t){var e=this.inscode[t];return e?String.fromCharCode(e):""},Object.defineProperties(e.prototype,i),e}(qg),Qg=function(t){function e(){t.apply(this,arguments)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={__fields:{}};return i.__fields.get=function(){return[["entityIndex",1,"uint16"],["modelIndex",1,"uint16"],["residueOffset",1,"uint32"],["residueCount",1,"uint32"],["chainname",4,"uint8"],["chainid",4,"uint8"]]},e.prototype.setChainname=function(t,e){var i=4*t;this.chainname[i]=e.charCodeAt(0),this.chainname[i+1]=e.charCodeAt(1),this.chainname[i+2]=e.charCodeAt(2),this.chainname[i+3]=e.charCodeAt(3)},e.prototype.getChainname=function(t){for(var e=this,i="",r=0;r<4;++r){var n=e.chainname[4*t+r];if(!n)break;i+=String.fromCharCode(n)}return i},e.prototype.setChainid=function(t,e){var i=4*t;this.chainid[i]=e.charCodeAt(0),this.chainid[i+1]=e.charCodeAt(1),this.chainid[i+2]=e.charCodeAt(2),this.chainid[i+3]=e.charCodeAt(3)},e.prototype.getChainid=function(t){for(var e=this,i="",r=0;r<4;++r){var n=e.chainid[4*t+r];if(!n)break;i+=String.fromCharCode(n)}return i},Object.defineProperties(e.prototype,i),e}(qg),Jg=function(t){function e(){t.apply(this,arguments)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={__fields:{}};return i.__fields.get=function(){return[["chainOffset",1,"uint32"],["chainCount",1,"uint32"]]},Object.defineProperties(e.prototype,i),e}(qg);Za.prototype={constructor:Za,getCenterIterator:function(t){function e(){var t=this.get(s);return s+=1,t}function i(e){e=Math.min(o-1,Math.max(0,e));var i=c[a%4],r=3*e;if(i.fromArray(n,r),t){var s,u,h,l=Math.min(t,e,o-e-1);for(u=1;u<=l;++u)s=3*u,h=(l+1-u)/(l+1),i.x+=h*n[r-s+0]+h*n[r+s+0],i.y+=h*n[r-s+1]+h*n[r+s+1],i.z+=h*n[r-s+2]+h*n[r+s+2];i.x/=l+1,i.y/=l+1,i.z/=l+1}return a+=1,i}function r(){a=0,s=-1}var n=this.getPosition().center,o=n.length/3,a=0,s=-1,c=[new g,new g,new g,new g];return{size:o,next:e,get:i,reset:r}},getColor:function(t){var e=this.polymer,i=e.structure,r=e.residueCount,n=e.residueIndexStart,o=new Float32Array(3*r),a=t||{};a.structure=i;for(var s=lf.getScheme(a),c=i.getResidueProxy(),u=i.getAtomProxy(),h=0;h<r;++h)c.index=n+h,u.index=c.traceAtomIndex,s.atomColorToArray(u,o,3*h);return{color:o}},getPicking:function(){for(var t=this.polymer,e=t.structure,i=t.residueCount,r=t.residueIndexStart,n=new Float32Array(i),o=e.getResidueProxy(),a=0;a<i;++a)o.index=r+a,n[a]=o.traceAtomIndex;return{picking:new $m(n,e)}},getSize:function(t,e){for(var i=this.polymer,r=i.structure,n=i.residueCount,o=i.residueIndexStart,a=new Float32Array(n),s=new ga(t,e),c=r.getResidueProxy(),u=r.getAtomProxy(),h=0;h<n;++h)c.index=o+h,u.index=c.traceAtomIndex,a[h]=s.atomRadius(u);return{size:a}},getPosition:function(){var t,e,i,r,n,o=this.polymer,a=o.structure,s=o.residueCount,c=s-3,u=new Float32Array(3*s),h=new Float32Array(3*s),l=new Float32Array(s),p=new Float32Array(s),d=new Float32Array(s),f=new Float32Array(s),m=new Float32Array(3*s),v=new g,y=new g,b=new g,x=new g,_=new g,w=new g,S=new g,A=new g,M=new g,P=new g,T=new g,E=new g(0,0,0),C="trace",I=a.getAtomProxy(),L=a.getAtomProxy(o.getAtomIndexByType(0,C)),R=a.getAtomProxy(o.getAtomIndexByType(1,C)),O=a.getAtomProxy(o.getAtomIndexByType(2,C));for(i=0;i<c;++i)I.index=L.index,L.index=R.index,R.index=O.index,O.index=o.getAtomIndexByType(i+3,C),e=3*i,v.subVectors(L,I),y.subVectors(R,L),b.subVectors(O,R),x.subVectors(v,y),_.subVectors(y,b),M.crossVectors(x,_).normalize(),M.toArray(h,e),i>0&&(l[i]=M.angleTo(P)),t=Math.cos(x.angleTo(_)),f[i]=180/Math.PI*Math.acos(t),r=x.length(),n=_.length(),p[i]=Math.sqrt(n*r)/Math.max(2,2*(1-t)),d[i]=Math.abs(y.dot(M)),w.copy(x).multiplyScalar(p[i]/r),S.copy(_).multiplyScalar(p[i]/n),w.subVectors(L,w),S.subVectors(R,S),w.toArray(u,e+3),S.toArray(u,e+6),T.subVectors(I,E),T.toArray(m,e),P.copy(M),E.copy(w);for(w.fromArray(u,3),S.fromArray(u,6),M.subVectors(w,S).normalize(),I.index=o.getAtomIndexByType(0,C),E.copy(I),A.copy(I),Ko(A,M,w),A.toArray(u,0),T.subVectors(E,w),T.toArray(m,0),w.fromArray(u,3*s-6),S.fromArray(u,3*s-9),M.subVectors(w,S).normalize(),I.index=o.getAtomIndexByType(s-1,C),E.copy(I),A.copy(I),Ko(A,M,w),A.toArray(u,3*s-3),i=s-3;i<s;++i)w.fromArray(u,3*i),I.index=o.getAtomIndexByType(i,C),E.copy(I),T.subVectors(E,w),T.toArray(m,3*i);var D=new Float32Array(s),N=new Float32Array(s),k=new Float32Array(s),B=new Float32Array(s);for(D[1]=p[0],N[1]=f[0],k[1]=p[0],i=2;i<s-2;++i)D[i]=.5*(p[i-2]+p[i-1]),N[i]=.5*(f[i-2]+f[i-1]),k[i]=.5*(d[i-2]+d[i-1]),w.fromArray(h,3*(i-2)),S.fromArray(h,3*(i-1)),B[i]=180/Math.PI*Math.acos(Math.cos(w.angleTo(S)));D[s-2]=p[s-4],N[s-2]=f[s-4],k[s-2]=d[s-4];var F=new Float32Array(3*s);for(Ro(h,F,0,0,3),Ro(h,F,0,3,3),i=2;i<s-2;++i)w.fromArray(h,3*(i-2)),S.fromArray(h,3*(i-1)),M.addVectors(S,w).multiplyScalar(.5).normalize(),M.toArray(F,3*i);return Ro(h,F,3*s-12,3*s-6,3),Ro(h,F,3*s-12,3*s-3,3),{center:u,axis:F,bending:B,radius:D,rise:k,twist:N,resdir:m}}},Ka.prototype={constructor:Ka,getAxis:function(t,e,i,r,n,o){t=t||30,e=e||2.5,i=void 0!==i&&i;var a=this.polymer,s=a.structure,c=a.residueCount,u=a.residueIndexStart,h=this.position,l=r||{};l.structure=s;for(var p,d,f=lf.getScheme(l),m=new ga(n,o),v=0,y=0,b=[],x=[],_=[],w=[],S=[],A=[],M=[],P=[],T=[],E=[],C=[],I=new g,L=new 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this.partList.forEach(function(e){t+=e.matrixList.length}),t},iv.prototype.isIdentity=function(t){if(1!==this.partList.length)return!1;var e=this.partList[0];if(1!==e.matrixList.length)return!1;if(!(new v).equals(e.matrixList[0]))return!1;var i=[];return t.eachChain(function(t){i.push(t.chainname)}),i=Mn(i),e.chainList.length===i.length},iv.prototype.getBoundingBox=function(t){var e=new st;return this.partList.forEach(function(i){var r=i.getBoundingBox(t);e.expandByPoint(r.min),e.expandByPoint(r.max)}),e},iv.prototype.getCenter=function(t){return this.getBoundingBox(t).getCenter()},iv.prototype.getSelection=function(){var t=[];return this.partList.forEach(function(e){t=t.concat(e.chainList)}),is(t)},Object.defineProperties(iv.prototype,rv);var nv=function(t,e){this.matrixList=t||[],this.chainList=e||[]},ov={type:{}};ov.type.get=function(){return"AssemblyPart"},nv.prototype._getCount=function(t,e){var i=0,r=this.chainList;return t.eachChain(function(t){(0===r.length||r.includes(t.chainname))&&(i+=t[e])}),this.matrixList.length*i},nv.prototype.getAtomCount=function(t){return this._getCount(t,"atomCount")},nv.prototype.getResidueCount=function(t){return this._getCount(t,"residueCount")},nv.prototype.getBoundingBox=function(t){var e=new st,i=new st,r=this.getSelection(),n=t.getBoundingBox(r);return this.matrixList.forEach(function(t){i.copy(n).applyMatrix4(t),e.expandByPoint(i.min),e.expandByPoint(i.max)}),e},nv.prototype.getSelection=function(){return is(this.chainList)},nv.prototype.getView=function(t){var e=this.getSelection();return e?t.getView(e):t},nv.prototype.getInstanceList=function(){for(var t=this,e=[],i=0,r=this.matrixList.length;i<r;++i)e.push({id:i+1,name:i,matrix:t.matrixList[i]});return e},Object.defineProperties(nv.prototype,ov);var av=function(){var e=function(t,e,i,r){for(var n=t.structure,o=t.residueIndexStart,a=n.getResidueProxy(),s=n.getResidueProxy(),c=n.getAtomProxy(),u=n.getAtomProxy(),h=Math.max(0,e-2);h<=e;++h)for(var l=2;l<5;++l)if(!(h+l>=t.residueCount)){a.index=o+h,s.index=o+h+l,c.index=a.traceAtomIndex,u.index=s.traceAtomIndex;var p=c.distanceTo(u);if(Math.abs(p-i[l-2])>r)return!1}return!0},i=function(t,i){return e(t,i,[5.45,5.18,6.37],2.1)},r=function(t,i){return e(t,i,[6.1,10.4,13],1.42)},n=function(t){for(var e=t.residueStore,n=t.residueIndexStart,o=0,a=t.residueCount;o<a;++o){var s="c";i(t,o)?s="h":r(t,o)&&(s="s"),e.sstruc[n+o]=s.charCodeAt(0)}},o=function(t){for(var e=t.residueStore,i=t.residueIndexStart,r=new Ka(t).position,n=new g,o=new g,a=0,s=t.residueCount;a<s;++a){n.fromArray(r.center,3*a),o.fromArray(r.center,3*a+3);var c=n.distanceTo(o);c<2&&c>1&&r.bending[a]<20&&(e.sstruc[i+a]="h".charCodeAt(0),e.sstruc[i+a+1]="h".charCodeAt(0))}};return function(e){t.Debug&&cf.time("calculateSecondaryStructure"),e.eachPolymer(function(t){if(!(t.residueCount<4)){if(t.isCg())o(t);else{if(!t.isProtein())return;n(t)}var e,i=0;t.eachResidue(function(t){t.sstruc===e?i+=1:(1===i&&(t.index-=1,t.sstruc="c"),i=1,e=t.sstruc)})}}),t.Debug&&cf.timeEnd("calculateSecondaryStructure")}}(),sv=["H","C","O","N","S","P"],cv=["NA","CL","FE"],uv=function(t,e,i){this.structure=t,i=i||ls(e),this.atomname=e,this.element=i,this.vdw=_g[i],this.covalent=wg[i]},hv=function(t){this.structure=t,this.dict={},this.list=[]};hv.prototype.add=function(t,e){var i=ds(t=t.toUpperCase(),e=e?e.toUpperCase():ls(t)),r=this.dict[i];if(void 0===r){var n=new uv(this.structure,t,e);r=this.list.length,this.dict[i]=r,this.list.push(n)}return r},hv.prototype.get=function(t){return this.list[t]};var lv=function(t,e,i,r,n,o){this.structure=t,this.resname=e,this.atomTypeIdList=i,this.hetero=r?1:0,this.chemCompType=n,this.bonds=o,this.rings=void 0,this.atomCount=i.length,this.moleculeType=this.getMoleculeType(),this.backboneType=this.getBackboneType(0),this.backboneEndType=this.getBackboneType(-1),this.backboneStartType=this.getBackboneType(1),this.backboneIndexList=this.getBackboneIndexList();var a=Ng[this.backboneType],s=Ng[this.backboneStartType],c=Ng[this.backboneEndType],u=this.getAtomIndexByName(a.trace);this.traceAtomIndex=void 0!==u?u:-1;var h=this.getAtomIndexByName(a.direction1);this.direction1AtomIndex=void 0!==h?h:-1;var l=this.getAtomIndexByName(a.direction2);this.direction2AtomIndex=void 0!==l?l:-1;var p=this.getAtomIndexByName(s.backboneStart);this.backboneStartAtomIndex=void 0!==p?p:-1;var d=this.getAtomIndexByName(c.backboneEnd);this.backboneEndAtomIndex=void 0!==d?d:-1;var f;f=Cg.includes(e)?this.getAtomIndexByName("N1"):this.getAtomIndexByName("N3"),this.rungEndAtomIndex=void 0!==f?f:-1,this.bondReferenceAtomIndices=[]};lv.prototype.getBackboneIndexList=function(){var t,e=[];switch(this.moleculeType){case 3:t=Og;break;case 4:case 5:t=Dg;break;default:return e}for(var i=this.structure.atomMap,r=this.atomTypeIdList,n=0,o=this.atomCount;n<o;++n){var a=i.get(r[n]);t.includes(a.atomname)&&e.push(n)}return e},lv.prototype.getMoleculeType=function(){return this.isProtein()?3:this.isRna()?4:this.isDna()?5:this.isWater()?1:this.isIon()?2:this.isSaccharide()?6:0},lv.prototype.getBackboneType=function(t){return this.hasProteinBackbone(t)?1:this.hasRnaBackbone(t)?2:this.hasDnaBackbone(t)?3:this.hasCgProteinBackbone(t)?4:this.hasCgRnaBackbone(t)?5:this.hasCgDnaBackbone(t)?6:lg},lv.prototype.isProtein=function(){return this.chemCompType?pg.includes(this.chemCompType):this.hasAtomWithName("CA","C","N")||Pg.includes(this.resname)},lv.prototype.isCg=function(){var t=this.backboneType;return 4===t||5===t||6===t},lv.prototype.isNucleic=function(){return this.isRna()||this.isDna()},lv.prototype.isRna=function(){return this.chemCompType?dg.includes(this.chemCompType):this.hasAtomWithName(["P","O3'","O3*"],["C4'","C4*"],["O2'","O2*","F2'","F2*"])||Tg.includes(this.resname)&&this.hasAtomWithName(["O2'","O2*","F2'","F2*"])},lv.prototype.isDna=function(){return this.chemCompType?fg.includes(this.chemCompType):this.hasAtomWithName(["P","O3'","O3*"],["C3'","C3*"])&&!this.hasAtomWithName(["O2'","O2*","F2'","F2*"])||Eg.includes(this.resname)},lv.prototype.isHetero=function(){return 1===this.hetero},lv.prototype.isIon=function(){return Lg.includes(this.resname)},lv.prototype.isWater=function(){return Ig.includes(this.resname)},lv.prototype.isSaccharide=function(){return this.chemCompType?mg.includes(this.chemCompType):Rg.includes(this.resname)},lv.prototype.hasBackboneAtoms=function(t,e){var i=Ng[e];return-1===t?this.hasAtomWithName(i.trace,i.backboneEnd,i.direction1,i.direction2):0===t?this.hasAtomWithName(i.trace,i.direction1,i.direction2):1===t?this.hasAtomWithName(i.trace,i.backboneStart,i.direction1,i.direction2):this.hasAtomWithName(i.trace,i.backboneStart,i.backboneEnd,i.direction1,i.direction2)},lv.prototype.hasProteinBackbone=function(t){return this.isProtein()&&this.hasBackboneAtoms(t,1)},lv.prototype.hasRnaBackbone=function(t){return this.isRna()&&this.hasBackboneAtoms(t,2)},lv.prototype.hasDnaBackbone=function(t){return this.isDna()&&this.hasBackboneAtoms(t,3)},lv.prototype.hasCgProteinBackbone=function(t){return this.isProtein()&&this.hasBackboneAtoms(t,4)},lv.prototype.hasCgRnaBackbone=function(t){return this.isRna()&&this.hasBackboneAtoms(t,5)},lv.prototype.hasCgDnaBackbone=function(t){return this.isDna()&&this.hasBackboneAtoms(t,6)},lv.prototype.hasBackbone=function(t){return this.hasProteinBackbone(t)||this.hasRnaBackbone(t)||this.hasDnaBackbone(t)||this.hasCgProteinBackbone(t)||this.hasCgRnaBackbone(t)||this.hasCgDnaBackbone(t)},lv.prototype.getAtomIndexByName=function(t){var e=this.atomCount,i=this.structure.atomMap,r=this.atomTypeIdList;if(Array.isArray(t))for(var n=0;n<e;++n){var o=r[n];if(t.includes(i.get(o).atomname))return n}else for(var a=0;a<e;++a){var s=r[a];if(t===i.get(s).atomname)return a}},lv.prototype.hasAtomWithName=function(){for(var t=arguments,e=this,i=arguments.length,r=0;r<i;++r)if(void 0!==t[r]&&void 0===e.getAtomIndexByName(t[r]))return!1;return!0},lv.prototype.getBonds=function(t){return void 0===this.bonds&&(this.bonds=as(t)),this.bonds},lv.prototype.getRings=function(){return void 0===this.rings&&this.calculateRings(),this.rings},lv.prototype.getBondGraph=function(){return void 0===this.bondGraph&&this.calculateBondGraph(),this.bondGraph},lv.prototype.calculateBondGraph=function(){for(var t=this.bondGraph={},e=this.getBonds(),i=e.atomIndices1.length,r=e.atomIndices1,n=e.atomIndices2,o=0;o<i;++o){var a=r[o],s=n[o];(t[a]=t[a]||[]).push(s),(t[s]=t[s]||[]).push(a)}},lv.prototype.calculateRings=function(){function t(a,s,c){if(i[a])throw Error("DFS revisited atom");i[a]=1,o.push(a);for(var u=s.length,h=0;h<u;++h){var l=s[h];if(0===i[l])e[l]&&e[l].length>=2?t(l,e[l],a):i[l]=2;else if(1===i[l]&&c&&c!=l){var p=[l];r[l]=1,n.push(p);for(var d=o.length-1;d>=0;--d){var f=o[d];if(f===l)break;p.push(f),r[f]=1}}}i[a]=2,o.pop()}for(var e=this.getBondGraph(),i=new Int8Array(this.atomCount),r=new Int8Array(this.atomCount),n=[],o=[],a=0;a<this.atomCount;++a)if(!i[a]){var s=e[a];!s||s.length<2?i[a]=2:(o.length=0,t(a,s))}this.rings={flags:r,rings:n}},lv.prototype.assignBondReferenceAtomIndices=function(){var t=this.getBondGraph(),e=this.getRings(),i=e.flags,r=e.rings,n=this.bonds.atomIndices1,o=this.bonds.atomIndices2,a=this.bonds.bondOrders,s=this.bondReferenceAtomIndices,c=this.bonds.atomIndices1.length;s.length=0;for(var u=0;u<c;++u)if(!(a[u]<=1)){var h=n[u],l=o[u];if(i[h]&&i[l]){for(var p=0;p<r.length&&void 0===s[u];++p)for(var d=r[p],f=null,m=!1,g=0;g<d.length;++g){var v=d[g];if(v===h||v===l?m=!0:f=v,m&&null!==f){s[u]=f;break}}if(void 0!==s[u])continue}if(t[h].length>1)for(var y=0;y<t[h].length;++y){var b=t[h][y];if(b!==l){s[u]=b;break}}else if(t[l].length>1)for(var x=0;x<t[l].length;++x){var _=t[l][x];if(_!==h){s[u]=_;break}}else;}},lv.prototype.getBondIndex=function(t,e){for(var i=this.bonds,r=i.atomIndices1,n=i.atomIndices2,o=r.indexOf(t),a=n.indexOf(e),s=a;-1!==o;){for(;-1!==a;){if(o===a)return o;a=n.indexOf(e,a+1)}o=r.indexOf(t,o+1),a=s}},lv.prototype.getBondReferenceAtomIndex=function(t,e){var i=this.getBondIndex(t,e);if(void 0!==i)return 0===this.bondReferenceAtomIndices.length&&this.assignBondReferenceAtomIndices(),this.bondReferenceAtomIndices[i]};var pv=function(t){this.structure=t,this.dict={},this.list=[]};pv.prototype.add=function(t,e,i,r,n){var o=fs(t=t.toUpperCase(),e,i,r),a=this.dict[o];if(void 0===a){var s=new lv(this.structure,t,e,i,r,n);a=this.list.length,this.dict[o]=a,this.list.push(s)}return a},pv.prototype.get=function(t){return this.list[t]};var dv=function(t,e){this.structure=t,this.bondStore=t.bondStore,this.index=e,this._v12=new g,this._v13=new g,this._ap1=this.structure.getAtomProxy(),this._ap2=this.structure.getAtomProxy(),this._ap3=this.structure.getAtomProxy()},fv={atom1:{},atom2:{},atomIndex1:{},atomIndex2:{},bondOrder:{}};fv.atom1.get=function(){return this.structure.getAtomProxy(this.atomIndex1)},fv.atom2.get=function(){return this.structure.getAtomProxy(this.atomIndex2)},fv.atomIndex1.get=function(){return this.bondStore.atomIndex1[this.index]},fv.atomIndex1.set=function(t){this.bondStore.atomIndex1[this.index]=t},fv.atomIndex2.get=function(){return this.bondStore.atomIndex2[this.index]},fv.atomIndex2.set=function(t){this.bondStore.atomIndex2[this.index]=t},fv.bondOrder.get=function(){return this.bondStore.bondOrder[this.index]},fv.bondOrder.set=function(t){this.bondStore.bondOrder[this.index]=t},dv.prototype.getReferenceAtomIndex=function(){var t=this._ap1,e=this._ap2;if(t.index=this.atomIndex1,e.index=this.atomIndex2,t.residueIndex===e.residueIndex){var i=t.index-t.residueAtomOffset,r=e.index-e.residueAtomOffset,n=t.residueType.getBondReferenceAtomIndex(i,r);if(void 0!==n)return n+t.residueAtomOffset;console.warn("No reference atom found",t.index,e.index)}},dv.prototype.calculateShiftDir=function(t){t||(t=new g);var e=this._ap1,i=this._ap2,r=this._ap3,n=this._v12,o=this._v13;e.index=this.atomIndex1,i.index=this.atomIndex2;var a=this.getReferenceAtomIndex();n.subVectors(e,i).normalize(),void 0!==a?(r.index=a,o.subVectors(e,r)):o.copy(e),o.normalize();var s=n.dot(o);return 1-Math.abs(s)<1e-5&&(o.set(1,0,0),s=n.dot(o),1-Math.abs(s)<1e-5&&(o.set(0,1,0),s=n.dot(o))),t.copy(o.sub(n.multiplyScalar(s))).normalize()},dv.prototype.qualifiedName=function(){return this.atomIndex1+"="+this.atomIndex2},dv.prototype.clone=function(){return new this.constructor(this.structure,this.index)},dv.prototype.toObject=function(){return{atomIndex1:this.atomIndex1,atomIndex2:this.atomIndex2,bondOrder:this.bondOrder}},Object.defineProperties(dv.prototype,fv);var mv=function(t,e){this.structure=t,this.chainStore=t.chainStore,this.residueStore=t.residueStore,this.atomStore=t.atomStore,this.residueMap=t.residueMap,this.atomMap=t.atomMap,this.index=e},gv={bondHash:{},entity:{},entityIndex:{},modelIndex:{},chainIndex:{},residue:{},residueIndex:{},sstruc:{},inscode:{},resno:{},chainname:{},chainid:{},residueType:{},atomType:{},residueAtomOffset:{},resname:{},hetero:{},atomname:{},element:{},vdw:{},covalent:{},x:{},y:{},z:{},serial:{},bfactor:{},occupancy:{},altloc:{}};gv.bondHash.get=function(){return this.structure.bondHash},gv.entity.get=function(){return this.structure.entityList[this.entityIndex]},gv.entityIndex.get=function(){return this.chainStore.entityIndex[this.chainIndex]},gv.modelIndex.get=function(){return this.chainStore.modelIndex[this.chainIndex]},gv.chainIndex.get=function(){return this.residueStore.chainIndex[this.residueIndex]},gv.residue.get=function(){return console.warn("residue - might be expensive"),this.structure.getResidueProxy(this.residueIndex)},gv.residueIndex.get=function(){return this.atomStore.residueIndex[this.index]},gv.residueIndex.set=function(t){this.atomStore.residueIndex[this.index]=t},gv.sstruc.get=function(){return this.residueStore.getSstruc(this.residueIndex)},gv.inscode.get=function(){return this.residueStore.getInscode(this.residueIndex)},gv.resno.get=function(){return this.residueStore.resno[this.residueIndex]},gv.chainname.get=function(){return this.chainStore.getChainname(this.chainIndex)},gv.chainid.get=function(){return this.chainStore.getChainid(this.chainIndex)},gv.residueType.get=function(){return this.residueMap.get(this.residueStore.residueTypeId[this.residueIndex])},gv.atomType.get=function(){return this.atomMap.get(this.atomStore.atomTypeId[this.index])},gv.residueAtomOffset.get=function(){return this.residueStore.atomOffset[this.residueIndex]},gv.resname.get=function(){return this.residueType.resname},gv.hetero.get=function(){return this.residueType.hetero},gv.atomname.get=function(){return this.atomType.atomname},gv.element.get=function(){return this.atomType.element},gv.vdw.get=function(){return this.atomType.vdw},gv.covalent.get=function(){return this.atomType.covalent},gv.x.get=function(){return this.atomStore.x[this.index]},gv.x.set=function(t){this.atomStore.x[this.index]=t},gv.y.get=function(){return this.atomStore.y[this.index]},gv.y.set=function(t){this.atomStore.y[this.index]=t},gv.z.get=function(){return this.atomStore.z[this.index]},gv.z.set=function(t){this.atomStore.z[this.index]=t},gv.serial.get=function(){return this.atomStore.serial[this.index]},gv.serial.set=function(t){this.atomStore.serial[this.index]=t},gv.bfactor.get=function(){return this.atomStore.bfactor[this.index]},gv.bfactor.set=function(t){this.atomStore.bfactor[this.index]=t},gv.occupancy.get=function(){return this.atomStore.occupancy[this.index]},gv.occupancy.set=function(t){this.atomStore.occupancy[this.index]=t},gv.altloc.get=function(){return this.atomStore.getAltloc(this.index)},gv.altloc.set=function(t){this.atomStore.setAltloc(this.index,t)},mv.prototype.eachBond=function(t,e){e=e||this.structure._bp;for(var i=this.index,r=this.bondHash,n=r.indexArray,o=r.countArray[i],a=r.offsetArray[i],s=0;s<o;++s)e.index=n[a+s],t(e)},mv.prototype.eachBondedAtom=function(t,e){e=e||this.structure._ap;var i=this.index;this.eachBond(function(r){i!==r.atomIndex1?e.index=r.atomIndex1:e.index=r.atomIndex2,t(e)})},mv.prototype.isBackbone=function(){var t=this.residueType.backboneIndexList;if(t.length>0){var e=this.residueStore.atomOffset[this.residueIndex];return t.includes(this.index-e)}return!1},mv.prototype.isPolymer=function(){if(this.structure.entityList.length>0)return this.entity.isPolymer();var t=this.residueType.moleculeType;return 3===t||4===t||5===t},mv.prototype.isSidechain=function(){return this.isPolymer()&&!this.isBackbone()},mv.prototype.isCg=function(){var t=this.residueType.backboneType;return 4===t||5===t||6===t},mv.prototype.isHetero=function(){return 1===this.residueType.hetero},mv.prototype.isProtein=function(){return 3===this.residueType.moleculeType},mv.prototype.isNucleic=function(){var t=this.residueType.moleculeType;return 4===t||5===t},mv.prototype.isRna=function(){return 4===this.residueType.moleculeType},mv.prototype.isDna=function(){return 5===this.residueType.moleculeType},mv.prototype.isWater=function(){return 1===this.residueType.moleculeType},mv.prototype.isIon=function(){return 2===this.residueType.moleculeType},mv.prototype.isSaccharide=function(){return 6===this.residueType.moleculeType},mv.prototype.isHelix=function(){return yg.includes(this.sstruc)},mv.prototype.isSheet=function(){return bg.includes(this.sstruc)},mv.prototype.isTurn=function(){return xg.includes(this.sstruc)&&this.isProtein()},mv.prototype.isBonded=function(){return 0!==this.bondHash.countArray[this.index]},mv.prototype.isRing=function(){return 1===this.residueType.getRings().flags[this.index-this.residueAtomOffset]},mv.prototype.distanceTo=function(t){var e=this.atomStore,i=t.atomStore,r=this.index,n=t.index,o=e.x[r]-i.x[n],a=e.y[r]-i.y[n],s=e.z[r]-i.z[n],c=o*o+a*a+s*s;return Math.sqrt(c)},mv.prototype.connectedTo=function(t){var e=this.atomStore,i=t.atomStore,r=this.index,n=t.index;if(e.altloc&&i.altloc){var o=e.altloc[r],a=i.altloc[n];if(0!==o&&0!==a&&32!==o&&32!==a&&o!==a)return!1}var s=e.x[r]-i.x[n],c=e.y[r]-i.y[n],u=e.z[r]-i.z[n],h=s*s+c*c+u*u;if(h<64&&this.isCg())return!0;if(isNaN(h))return!1;var l=this.covalent+t.covalent,p=l+.3,d=l-.5;return h<p*p&&h>d*d},mv.prototype.positionFromArray=function(t,e){return void 0===e&&(e=0),this.x=t[e+0],this.y=t[e+1],this.z=t[e+2],this},mv.prototype.positionToArray=function(t,e){void 0===t&&(t=[]),void 0===e&&(e=0);var i=this.index,r=this.atomStore;return t[e+0]=r.x[i],t[e+1]=r.y[i],t[e+2]=r.z[i],t},mv.prototype.positionToVector3=function(t){return void 0===t&&(t=new g),t.x=this.x,t.y=this.y,t.z=this.z,t},mv.prototype.positionFromVector3=function(t){return this.x=t.x,this.y=t.y,this.z=t.z,this},mv.prototype.getResidueBonds=function(t){var e,i,r,n,o=this.residueAtomOffset,a=this.index-this.residueAtomOffset,s=this.residueType.getBonds(),c=s.atomIndices1,u=s.atomIndices2;for(t||(n=[]),e=c.indexOf(a);-1!==e;){if(r=u[e]+o,t)return r;n.push(r),e=c.indexOf(a,e+1)}for(i=u.indexOf(a);-1!==i;){if(r=c[i]+o,t)return r;n.push(r),i=u.indexOf(a,i+1)}return n},mv.prototype.qualifiedName=function(t){var e="";return this.resname&&!t&&(e+="["+this.resname+"]"),void 0!==this.resno&&(e+=this.resno),this.inscode&&(e+="^"+this.inscode),this.chainname&&(e+=":"+this.chainname),this.atomname&&(e+="."+this.atomname),this.altloc&&(e+="%"+this.altloc),this.structure.modelStore.count>1&&(e+="/"+this.modelIndex),e},mv.prototype.clone=function(){return new this.constructor(this.structure,this.index)},mv.prototype.toObject=function(){return{index:this.index,residueIndex:this.residueIndex,atomno:this.atomno,resname:this.resname,x:this.x,y:this.y,z:this.z,element:this.element,chainname:this.chainname,resno:this.resno,serial:this.serial,vdw:this.vdw,covalent:this.covalent,hetero:this.hetero,bfactor:this.bfactor,altloc:this.altloc,atomname:this.atomname,modelindex:this.modelindex}},Object.defineProperties(mv.prototype,gv);var vv=function(t,e){this.structure=t,this.chainStore=t.chainStore,this.residueStore=t.residueStore,this.atomStore=t.atomStore,this.residueMap=t.residueMap,this.atomMap=t.atomMap,this.index=e},yv={entity:{},entityIndex:{},chain:{},chainIndex:{},atomOffset:{},atomCount:{},atomEnd:{},modelIndex:{},chainname:{},chainid:{},resno:{},sstruc:{},inscode:{},residueType:{},resname:{},hetero:{},moleculeType:{},backboneType:{},backboneStartType:{},backboneEndType:{},traceAtomIndex:{},direction1AtomIndex:{},direction2AtomIndex:{},backboneStartAtomIndex:{},backboneEndAtomIndex:{},rungEndAtomIndex:{}};yv.entity.get=function(){return this.structure.entityList[this.entityIndex]},yv.entityIndex.get=function(){return this.chainStore.entityIndex[this.chainIndex]},yv.chain.get=function(){return this.structure.getChainProxy(this.chainIndex)},yv.chainIndex.get=function(){return this.residueStore.chainIndex[this.index]},yv.chainIndex.set=function(t){this.residueStore.chainIndex[this.index]=t},yv.atomOffset.get=function(){return this.residueStore.atomOffset[this.index]},yv.atomOffset.set=function(t){this.residueStore.atomOffset[this.index]=t},yv.atomCount.get=function(){return this.residueStore.atomCount[this.index]},yv.atomCount.set=function(t){this.residueStore.atomCount[this.index]=t},yv.atomEnd.get=function(){return this.atomOffset+this.atomCount-1},yv.modelIndex.get=function(){return this.chainStore.modelIndex[this.chainIndex]},yv.chainname.get=function(){return this.chainStore.getChainname(this.chainIndex)},yv.chainid.get=function(){return this.chainStore.getChainid(this.chainIndex)},yv.resno.get=function(){return this.residueStore.resno[this.index]},yv.resno.set=function(t){this.residueStore.resno[this.index]=t},yv.sstruc.get=function(){return this.residueStore.getSstruc(this.index)},yv.sstruc.set=function(t){this.residueStore.setSstruc(this.index,t)},yv.inscode.get=function(){return this.residueStore.getInscode(this.index)},yv.inscode.set=function(t){this.residueStore.getInscode(this.index,t)},yv.residueType.get=function(){return this.residueMap.get(this.residueStore.residueTypeId[this.index])},yv.resname.get=function(){return this.residueType.resname},yv.hetero.get=function(){return this.residueType.hetero},yv.moleculeType.get=function(){return this.residueType.moleculeType},yv.backboneType.get=function(){return this.residueType.backboneType},yv.backboneStartType.get=function(){return this.residueType.backboneStartType},yv.backboneEndType.get=function(){return this.residueType.backboneEndType},yv.traceAtomIndex.get=function(){return this.residueType.traceAtomIndex+this.atomOffset},yv.direction1AtomIndex.get=function(){return this.residueType.direction1AtomIndex+this.atomOffset},yv.direction2AtomIndex.get=function(){return this.residueType.direction2AtomIndex+this.atomOffset},yv.backboneStartAtomIndex.get=function(){return this.residueType.backboneStartAtomIndex+this.atomOffset},yv.backboneEndAtomIndex.get=function(){return this.residueType.backboneEndAtomIndex+this.atomOffset},yv.rungEndAtomIndex.get=function(){return this.residueType.rungEndAtomIndex+this.atomOffset},vv.prototype.eachAtom=function(t,e){var i,r=this.atomCount,n=this.atomOffset,o=this.structure._ap,a=n+r;if(e&&e.atomOnlyTest){var s=e.atomOnlyTest;for(i=n;i<a;++i)o.index=i,s(o)&&t(o)}else for(i=n;i<a;++i)o.index=i,t(o)},vv.prototype.isProtein=function(){return 3===this.residueType.moleculeType},vv.prototype.isNucleic=function(){var t=this.residueType.moleculeType;return 4===t||5===t},vv.prototype.isRna=function(){return 4===this.residueType.moleculeType},vv.prototype.isDna=function(){return 5===this.residueType.moleculeType},vv.prototype.isCg=function(){var t=this.residueType.backboneType;return 4===t||5===t||6===t},vv.prototype.isPolymer=function(){if(this.structure.entityList.length>0)return this.entity.isPolymer();var t=this.residueType.moleculeType;return 3===t||4===t||5===t},vv.prototype.isHetero=function(){return 1===this.residueType.hetero},vv.prototype.isWater=function(){return 1===this.residueType.moleculeType},vv.prototype.isIon=function(){return 2===this.residueType.moleculeType},vv.prototype.isSaccharide=function(){return 6===this.residueType.moleculeType},vv.prototype.isHelix=function(){return yg.includes(this.sstruc)},vv.prototype.isSheet=function(){return bg.includes(this.sstruc)},vv.prototype.isTurn=function(){return xg.includes(this.sstruc)&&this.isProtein()},vv.prototype.getAtomType=function(t){return this.atomMap.get(this.atomStore.atomTypeId[t])},vv.prototype.getResname1=function(){return Mg[this.resname.toUpperCase()]||"X"},vv.prototype.getBackboneType=function(t){switch(t){case-1:return this.residueType.backboneStartType;case 1:return this.residueType.backboneEndType;default:return this.residueType.backboneType}},vv.prototype.getAtomIndexByName=function(t){var e=this.residueType.getAtomIndexByName(t);return void 0!==e&&(e+=this.atomOffset),e},vv.prototype.getAtomByName=function(t){return this.residueType.getAtomByName(t)},vv.prototype.hasAtomWithName=function(t){return this.residueType.hasAtomWithName(t)},vv.prototype.getAtomnameList=function(){var t=this;console.warn("getAtomnameList - might be expensive");for(var e=this.atomCount,i=this.atomOffset,r=new Array(e),n=0;n<e;++n)r[n]=t.getAtomType(i+n).atomname;return r},vv.prototype.connectedTo=function(t){var e=this.structure.getAtomProxy(this.backboneEndAtomIndex),i=this.structure.getAtomProxy(t.backboneStartAtomIndex);return!(!e||!i)&&e.connectedTo(i)},vv.prototype.getNextConnectedResidue=function(){var t=this.chainStore.residueOffset[this.chainIndex],e=this.chainStore.residueCount[this.chainIndex],i=this.index+1;if(i<t+e){var r=this.structure.getResidueProxy(i);if(this.connectedTo(r))return r}else if(i===t+e){var n=this.structure.getResidueProxy(t);if(this.connectedTo(n))return n}},vv.prototype.getPreviousConnectedResidue=function(){var t=this.chainStore.residueOffset[this.chainIndex],e=this.index-1;if(e>=t){var i=this.structure.getResidueProxy(e);if(i.connectedTo(this))return i}else if(e===t-1){var r=this.chainStore.residueCount[this.chainIndex],n=this.structure.getResidueProxy(t+r-1);if(n.connectedTo(this))return n}},vv.prototype.getBonds=function(){return this.residueType.getBonds(this)},vv.prototype.getRings=function(){return this.residueType.getRings()},vv.prototype.qualifiedName=function(t){var e="";return this.resname&&!t&&(e+="["+this.resname+"]"),void 0!==this.resno&&(e+=this.resno),this.inscode&&(e+="^"+this.inscode),this.chain&&(e+=":"+this.chainname),e+="/"+this.modelIndex},vv.prototype.clone=function(){return new this.constructor(this.structure,this.index)},vv.prototype.toObject=function(){return{index:this.index,chainIndex:this.chainIndex,atomOffset:this.atomOffset,atomCount:this.atomCount,resno:this.resno,resname:this.resname,sstruc:this.sstruc}},Object.defineProperties(vv.prototype,yv);var bv=function(t,e,i){this.structure=t,this.chainStore=t.chainStore,this.residueStore=t.residueStore,this.atomStore=t.atomStore,this.residueIndexStart=e,this.residueIndexEnd=i,this.residueCount=i-e+1;var r=this.structure.getResidueProxy(this.residueIndexStart),n=this.structure.getResidueProxy(this.residueIndexEnd);this.isPrevConnected=void 0!==r.getPreviousConnectedResidue();var o=n.getNextConnectedResidue();this.isNextConnected=void 0!==o,this.isNextNextConnected=this.isNextConnected&&void 0!==o.getNextConnectedResidue(),this.isCyclic=n.connectedTo(r),this.__residueProxy=this.structure.getResidueProxy()},xv={chainIndex:{},modelIndex:{},chainname:{}};xv.chainIndex.get=function(){return this.residueStore.chainIndex[this.residueIndexStart]},xv.modelIndex.get=function(){return this.chainStore.modelIndex[this.chainIndex]},xv.chainname.get=function(){return this.chainStore.getChainname(this.chainIndex)},bv.prototype.isProtein=function(){return this.__residueProxy.index=this.residueIndexStart,this.__residueProxy.isProtein()},bv.prototype.isCg=function(){return this.__residueProxy.index=this.residueIndexStart,this.__residueProxy.isCg()},bv.prototype.isNucleic=function(){return this.__residueProxy.index=this.residueIndexStart,this.__residueProxy.isNucleic()},bv.prototype.getMoleculeType=function(){return this.__residueProxy.index=this.residueIndexStart,this.__residueProxy.moleculeType},bv.prototype.getBackboneType=function(t){return this.__residueProxy.index=this.residueIndexStart,this.__residueProxy.getBackboneType(t)},bv.prototype.getAtomIndexByType=function(t,e){this.isCyclic?-1===t?t=this.residueCount-1:t===this.residueCount&&(t=0):(-1!==t||this.isPrevConnected||(t+=1),t!==this.residueCount||this.isNextNextConnected||(t-=1));var i=this.__residueProxy;i.index=this.residueIndexStart+t;var r;switch(e){case"trace":r=i.traceAtomIndex;break;case"direction1":r=i.direction1AtomIndex;break;case"direction2":r=i.direction2AtomIndex;break;default:var n=i.getAtomByName(e);r=n?n.index:void 0}return r},bv.prototype.eachAtom=function(t,e){this.eachResidue(function(i){i.eachAtom(t,e)},e)},bv.prototype.eachAtomN=function(t,e,i){var r,n=this,o=this.residueCount,a=new Array(t);for(r=0;r<t;++r)a[r]=n.structure.getAtomProxy(n.getAtomIndexByType(r,i));e.apply(this,a);for(var s=t;s<o;++s){for(r=1;r<t;++r)a[r-1].index=a[r].index;a[t-1].index=n.getAtomIndexByType(s,i),e.apply(n,a)}},bv.prototype.eachAtomN2=function(t,e,i){var r=this,n=this.atomOffset,o=this.atomCount,a=n+o;if(!(o<t)){for(var s=new Array(t),c=0;c<t;++c)s[c]=r.structure.getAtomProxy();var u=this.structure.atomSetCache["__"+i];void 0===u&&(cf.warn("no precomputed atomSet for: "+i),u=this.structure.getAtomSet(!1),this.eachResidue(function(t){var e=t.getAtomByName(i);u.set(e.index)}));var h=0;u.forEach(function(i){if(i>=n&&i<a){for(var r=1;r<t;++r)s[r-1].index=s[r].index;s[t-1].index=i,(h+=1)>=t&&e.apply(this,s)}})}},bv.prototype.eachResidue=function(t){for(var e=this.structure.getResidueProxy(),i=this.residueCount,r=this.residueIndexStart,n=0;n<i;++n)e.index=r+n,t(e)},bv.prototype.qualifiedName=function(){var t=this.structure.getResidueProxy(this.residueIndexStart),e=this.structure.getResidueProxy(this.residueIndexEnd);return t.qualifiedName()+" - "+e.qualifiedName()},Object.defineProperties(bv.prototype,xv);var _v=function(t,e){this.structure=t,this.chainStore=t.chainStore,this.residueStore=t.residueStore,this.index=e},wv={entity:{},model:{},entityIndex:{},modelIndex:{},residueOffset:{},residueCount:{},residueEnd:{},atomOffset:{},atomEnd:{},atomCount:{},chainname:{},chainid:{}};wv.entity.get=function(){return this.structure.entityList[this.entityIndex]},wv.model.get=function(){return this.structure.getModelProxy(this.modelIndex)},wv.entityIndex.get=function(){return this.chainStore.entityIndex[this.index]},wv.entityIndex.set=function(t){this.chainStore.entityIndex[this.index]=t},wv.modelIndex.get=function(){return this.chainStore.modelIndex[this.index]},wv.modelIndex.set=function(t){this.chainStore.modelIndex[this.index]=t},wv.residueOffset.get=function(){return this.chainStore.residueOffset[this.index]},wv.residueOffset.set=function(t){this.chainStore.residueOffset[this.index]=t},wv.residueCount.get=function(){return this.chainStore.residueCount[this.index]},wv.residueCount.set=function(t){this.chainStore.residueCount[this.index]=t},wv.residueEnd.get=function(){return this.residueOffset+this.residueCount-1},wv.atomOffset.get=function(){return this.residueStore.atomOffset[this.residueOffset]},wv.atomEnd.get=function(){return this.residueStore.atomOffset[this.residueEnd]+this.residueStore.atomCount[this.residueEnd]-1},wv.atomCount.get=function(){return 0===this.residueCount?0:this.atomEnd-this.atomOffset+1},wv.chainname.get=function(){return this.chainStore.getChainname(this.index)},wv.chainname.set=function(t){this.chainStore.setChainname(this.index,t)},wv.chainid.get=function(){return this.chainStore.getChainid(this.index)},wv.chainid.set=function(t){this.chainStore.setChainid(this.index,t)},_v.prototype.eachAtom=function(t,e){this.eachResidue(function(i){i.eachAtom(t,e)},e)},_v.prototype.eachResidue=function(t,e){var i,r=this.residueCount,n=this.residueOffset,o=this.structure._rp,a=n+r;if(e&&e.test){var s=e.residueOnlyTest;if(s)for(i=n;i<a;++i)o.index=i,s(o)&&t(o,e);else for(i=n;i<a;++i)o.index=i,t(o,e)}else for(i=n;i<a;++i)o.index=i,t(o)},_v.prototype.eachResidueN=function(t,e){var i,r=this,n=this.residueCount,o=this.residueOffset,a=o+n;if(!(n<t)){var s=new Array(t);for(i=0;i<t;++i)s[i]=r.structure.getResidueProxy(o+i);e.apply(this,s);for(var c=o+t;c<a;++c){for(i=0;i<t;++i)s[i].index+=1;e.apply(r,s)}}},_v.prototype.eachPolymer=function(t,e){for(var i,r,n=e?e.residueOnlyTest:void 0,o=this.model.structure,a=this.residueCount,s=this.residueOffset,c=s+a,u=this.structure.getResidueProxy(),h=this.structure.getResidueProxy(s),l=this.structure.getAtomProxy(),p=this.structure.getAtomProxy(),d=!0,f=s+1;f<c;++f){u.index=h.index,h.index=f,d&&(i=u.index,d=!1),r=h.index;var m=d?u.backboneEndType:u.backboneType,g=h.backboneType;m!==lg&&m===g?(l.index=u.backboneEndAtomIndex,p.index=h.backboneStartAtomIndex,l&&p&&l.connectedTo(p)&&(!n||n(u)&&n(h))||(u.index-i>1&&t(new bv(o,i,u.index)),i=r)):(m!==lg&&u.index-i>1&&t(new bv(o,i,u.index)),i=r)}r-i>1&&this.structure.getResidueProxy(i).backboneStartType&&t(new bv(o,i,r))},_v.prototype.qualifiedName=function(){return":"+this.chainname+"/"+this.modelIndex},_v.prototype.clone=function(){return new this.constructor(this.structure,this.index)},_v.prototype.toObject=function(){return{index:this.index,residueOffset:this.residueOffset,residueCount:this.residueCount,chainname:this.chainname}},Object.defineProperties(_v.prototype,wv);var Sv=function(t,e){this.structure=t,this.modelStore=t.modelStore,this.chainStore=t.chainStore,this.residueStore=t.residueStore,this.index=e},Av={chainOffset:{},chainCount:{},residueOffset:{},atomOffset:{},chainEnd:{},residueEnd:{},atomEnd:{},residueCount:{},atomCount:{}};Av.chainOffset.get=function(){return this.modelStore.chainOffset[this.index]},Av.chainOffset.set=function(t){this.modelStore.chainOffset[this.index]=t},Av.chainCount.get=function(){return this.modelStore.chainCount[this.index]},Av.chainCount.set=function(t){this.modelStore.chainCount[this.index]=t},Av.residueOffset.get=function(){return this.chainStore.residueOffset[this.chainOffset]},Av.atomOffset.get=function(){return this.residueStore.atomOffset[this.residueOffset]},Av.chainEnd.get=function(){return this.chainOffset+this.chainCount-1},Av.residueEnd.get=function(){return this.chainStore.residueOffset[this.chainEnd]+this.chainStore.residueCount[this.chainEnd]-1},Av.atomEnd.get=function(){return this.residueStore.atomOffset[this.residueEnd]+this.residueStore.atomCount[this.residueEnd]-1},Av.residueCount.get=function(){return 0===this.chainCount?0:this.residueEnd-this.residueOffset+1},Av.atomCount.get=function(){return 0===this.residueCount?0:this.atomEnd-this.atomOffset+1},Sv.prototype.eachAtom=function(t,e){this.eachChain(function(i){i.eachAtom(t,e)},e)},Sv.prototype.eachResidue=function(t,e){this.eachChain(function(i){i.eachResidue(t,e)},e)},Sv.prototype.eachPolymer=function(t,e){if(e&&e.chainOnlyTest){var i=e.chainOnlyTest;this.eachChain(function(r){i(r)&&r.eachPolymer(t,e)})}else this.eachChain(function(i){i.eachPolymer(t,e)})},Sv.prototype.eachChain=function(t,e){var i,r=this.chainCount,n=this.chainOffset,o=this.structure._cp,a=n+r;if(e&&e.test){var s=e.chainOnlyTest;if(s)for(i=n;i<a;++i)o.index=i,s(o)&&t(o,e);else for(i=n;i<a;++i)o.index=i,t(o,e)}else for(i=n;i<a;++i)o.index=i,t(o)},Sv.prototype.qualifiedName=function(){return"/"+this.index},Sv.prototype.clone=function(){return new this.constructor(this.structure,this.index)},Sv.prototype.toObject=function(){return{index:this.index,chainOffset:this.chainOffset,chainCount:this.chainCount}},Object.defineProperties(Sv.prototype,Av);var Mv=function(t,e){this.signals={refreshed:new io},this.init(t,e)},Pv={type:{}};Mv.prototype.init=function(t,e){this.name=t,this.path=e,this.title="",this.id="",this.header={},this.extraData={},this.atomSetCache=void 0,this.atomSetDict={},this.biomolDict={},this.entityList=[],this.unitcell=void 0,this.frames=[],this.boxes=[],this.validation=void 0,this.bondStore=new Yg(0),this.backboneBondStore=new Yg(0),this.rungBondStore=new Yg(0),this.atomStore=new Zg(0),this.residueStore=new Kg(0),this.chainStore=new Qg(0),this.modelStore=new Jg(0),this.atomMap=new hv(this),this.residueMap=new pv(this),this.bondHash=void 0,this.spatialHash=void 0,this.atomSet=void 0,this.bondSet=void 0,this.center=void 0,this.boundingBox=void 0,this._bp=this.getBondProxy(),this._ap=this.getAtomProxy(),this._rp=this.getResidueProxy(),this._cp=this.getChainProxy()},Pv.type.get=function(){return"Structure"},Mv.prototype.finalizeAtoms=function(){this.atomSet=this.getAtomSet(),this.atomCount=this.atomStore.count,this.boundingBox=this.getBoundingBox(),this.center=this.boundingBox.getCenter(),this.spatialHash=new Fa(this.atomStore,this.boundingBox)},Mv.prototype.finalizeBonds=function(){var t=this;this.bondSet=this.getBondSet(),this.bondCount=this.bondStore.count,this.bondHash=new Xg(this.bondStore,this.atomStore.count),this.atomSetCache={},this.atomSetDict.rung||(this.atomSetDict.rung=this.getAtomSet(!1));for(var e in t.atomSetDict)t.atomSetCache["__"+e]=t.atomSetDict[e].clone()},Mv.prototype.getBondProxy=function(t){return new dv(this,t)},Mv.prototype.getAtomProxy=function(t){return new mv(this,t)},Mv.prototype.getResidueProxy=function(t){return new vv(this,t)},Mv.prototype.getChainProxy=function(t){return new _v(this,t)},Mv.prototype.getModelProxy=function(t){return new Sv(this,t)},Mv.prototype.getBondSet=function(){var t=this.bondStore.count,e=new og(t),i=this.atomSet;if(i)for(var r=this.getBondProxy(),n=0;n<t;++n)r.index=n,i.isSet(r.atomIndex1,r.atomIndex2)&&e.set(r.index);else e.setAll();return e},Mv.prototype.getBackboneBondSet=function(){var t=this.backboneBondStore.count,e=new og(t),i=this.atomSetCache.__backbone;if(i){var r=this.getBondProxy();r.bondStore=this.backboneBondStore;for(var n=0;n<t;++n)r.index=n,i.isSet(r.atomIndex1,r.atomIndex2)&&e.set(r.index)}else e.set_all(!0);return e},Mv.prototype.getRungBondSet=function(){var t=this.rungBondStore.count,e=new og(t),i=this.atomSetCache.__rung;if(i){var r=this.getBondProxy();r.bondStore=this.rungBondStore;for(var n=0;n<t;++n)r.index=n,i.isSet(r.atomIndex1,r.atomIndex2)&&e.set(r.index)}else e.set_all(!0);return e},Mv.prototype.getAtomSet=function(t){var e,i=this.atomStore.count;if(t instanceof og)e=t;else if(t&&t.test){var r=t.string;r in this.atomSetCache?e=this.atomSetCache[r]:(e=new og(i),this.eachAtom(function(t){e.set(t.index)},t),this.atomSetCache[r]=e)}else e=!1===t?new og(i):new og(i,!0);return e},Mv.prototype.getAtomSetWithinSelection=function(t,e){var i=this.spatialHash,r=this.getAtomSet(!1),n=this.getAtomProxy();return this.getAtomSet(t).forEach(function(t){n.index=t,i.within(n.x,n.y,n.z,e).forEach(function(t){r.set(t)})}),r},Mv.prototype.getAtomSetWithinPoint=function(t,e){var i=t,r=this.getAtomSet(!1);return this.spatialHash.within(i.x,i.y,i.z,e).forEach(function(t){r.set(t)}),r},Mv.prototype.getAtomSetWithinVolume=function(t,e,i,r,n){for(var o=this,a=new Hg(t,i,r,n),s=a.getDataPosition(),c=s.length,u=a.matrix.getMaxScaleOnAxis(),h=this.getAtomSet(!1),l=0;l<c;l+=3)o.spatialHash.within(s[l],s[l+1],s[l+2],u).forEach(function(t){h.set(t)});return h},Mv.prototype.getAtomSetWithinGroup=function(t){var e=this.atomStore.residueIndex,i=this.getAtomSet(!1),r=this.getResidueProxy();return this.getAtomSet(t).forEach(function(t){r.index=e[t];for(var n=r.atomOffset;n<=r.atomEnd;++n)i.set(n)}),i},Mv.prototype.getSelection=function(){return!1},Mv.prototype.getStructure=function(){return this},Mv.prototype.eachEntity=function(t,e){this.entityList.forEach(function(i){void 0!==e&&i.getEntityType()!==e||t(i)})},Mv.prototype.eachBond=function(t,e){var i,r=this.getBondProxy();if(e&&e.test&&(i=this.getBondSet(e),this.bondSet&&i.intersection(this.bondSet)),i)i.forEach(function(e){r.index=e,t(r)});else for(var n=this.bondStore.count,o=0;o<n;++o)r.index=o,t(r)},Mv.prototype.eachAtom=function(t,e){if(e&&e.test)this.eachModel(function(i){i.eachAtom(t,e)},e);else for(var i=this.atomStore.count,r=this.getAtomProxy(),n=0;n<i;++n)r.index=n,t(r)},Mv.prototype.eachResidue=function(t,e){var i;if(e&&e.test){var r=this.modelStore.count,n=this.getModelProxy(),o=e.modelOnlyTest;if(o)for(i=0;i<r;++i)n.index=i,o(n)&&n.eachResidue(t,e);else for(i=0;i<r;++i)n.index=i,n.eachResidue(t,e)}else{var a=this.residueStore.count,s=this.getResidueProxy();for(i=0;i<a;++i)s.index=i,t(s)}},Mv.prototype.eachResidueN=function(t,e){var i,r,n=this,o=this.residueStore.count;if(!(o<t)){var a=new Array(t);for(i=0;i<t;++i)a[i]=n.getResidueProxy(i);for(e.apply(this,a),r=t;r<o;++r){for(i=0;i<t;++i)a[i].index+=1;e.apply(n,a)}}},Mv.prototype.eachPolymer=function(t,e){if(e&&e.modelOnlyTest){var i=e.modelOnlyTest;this.eachModel(function(r){i(r)&&r.eachPolymer(t,e)})}else this.eachModel(function(i){i.eachPolymer(t,e)})},Mv.prototype.eachChain=function(t,e){if(e&&e.test)this.eachModel(function(i){i.eachChain(t,e)});else for(var i=this.chainStore.count,r=this.getChainProxy(),n=0;n<i;++n)r.index=n,t(r)},Mv.prototype.eachModel=function(t,e){var i,r=this.modelStore.count,n=this.getModelProxy();if(e&&e.test){var o=e.modelOnlyTest;if(o)for(i=0;i<r;++i)n.index=i,o(n)&&t(n,e);else for(i=0;i<r;++i)n.index=i,t(n,e)}else for(i=0;i<r;++i)n.index=i,t(n)},Mv.prototype.getAtomData=function(t){var e=Object.assign({},t);e.colorParams&&(e.colorParams.structure=this.getStructure());var i,r,n,o,a,s,c,u=e.what,h=dn(e.atomSet,this.atomSet),l={},p=this.getAtomProxy(),d=h.getSize();return u&&!u.position||(n=new Float32Array(3*d),l.position=n),u&&!u.color||(o=new Float32Array(3*d),l.color=o,r=lf.getScheme(e.colorParams)),u&&!u.picking||(a=new Float32Array(d),l.picking=new $m(a,this.getStructure())),u&&!u.radius||(s=new Float32Array(d),l.radius=s,i=new ga(e.radiusParams.radius,e.radiusParams.scale)),u&&!u.index||(c=new Float32Array(d),l.index=c),h.forEach(function(t,e){var u=3*e;p.index=t,n&&p.positionToArray(n,u),o&&r.atomColorToArray(p,o,u),a&&(a[e]=t),s&&(s[e]=i.atomRadius(p)),c&&(c[e]=t)}),l},Mv.prototype.getBondData=function(t){var e=Object.assign({},t);e.colorParams&&(e.colorParams.structure=this.getStructure());var i,r,n,o,a,s,c,u,h,l=e.what,p=dn(e.bondSet,this.bondSet),d=dn(e.multipleBond,"off"),f="off"!==d,m="offset"===d,v=dn(e.bondScale,.4),y=dn(e.bondSpacing,1),b={},x=this.getBondProxy();e.bondStore&&(x.bondStore=e.bondStore);var _,w=this.getAtomProxy(),S=this.getAtomProxy();if(f){var A=x.bondStore.bondOrder;_=0,p.forEach(function(t){_+=A[t]})}else _=p.getSize();l&&!l.position||(n=new Float32Array(3*_),o=new Float32Array(3*_),b.position1=n,b.position2=o),l&&!l.color||(a=new Float32Array(3*_),s=new Float32Array(3*_),b.color=a,b.color2=s,r=lf.getScheme(e.colorParams)),l&&!l.picking||(c=new Float32Array(_),b.picking=new Wm(c,this.getStructure(),e.bondStore)),(!l||l.radius||f&&l.position)&&(i=new ga(e.radiusParams.radius,e.radiusParams.scale)),l&&!l.radius||(u=new Float32Array(_),b.radius=u,e.radius2&&(h=new Float32Array(_),b.radius2=h));var M,P,T,E,C,I,L,R=0,O=new g,D=new g,N=new g;return p.forEach(function(t){if(P=3*R,x.index=t,w.index=x.atomIndex1,S.index=x.atomIndex2,E=x.bondOrder,n&&(f&&E>1?(C=i.atomRadius(w),I=C*v/(.5*E),x.calculateShiftDir(N),m?(L=2*y*C,N.multiplyScalar(L),N.negate(),D.subVectors(S,w).multiplyScalar(Math.max(.1,L/1.88)),w.positionToArray(n,P),S.positionToArray(o,P),E>=2&&(O.addVectors(w,N).add(D).toArray(n,P+3),O.addVectors(S,N).sub(D).toArray(o,P+3),E>=3&&(O.subVectors(w,N).add(D).toArray(n,P+6),O.subVectors(S,N).sub(D).toArray(o,P+6)))):(L=(y-v)*C,N.multiplyScalar(L),2===E?(O.addVectors(w,N).toArray(n,P),O.subVectors(w,N).toArray(n,P+3),O.addVectors(S,N).toArray(o,P),O.subVectors(S,N).toArray(o,P+3)):3===E?(w.positionToArray(n,P),O.addVectors(w,N).toArray(n,P+3),O.subVectors(w,N).toArray(n,P+6),S.positionToArray(o,P),O.addVectors(S,N).toArray(o,P+3),O.subVectors(S,N).toArray(o,P+6)):(w.positionToArray(n,P),S.positionToArray(o,P)))):(w.positionToArray(n,P),S.positionToArray(o,P))),a&&(r.bondColorToArray(x,1,a,P),r.bondColorToArray(x,0,s,P),f&&E>1))for(M=1;M<E;++M)Oo(a,P,T=3*M+P,3),Oo(s,P,T,3);if(c&&(c[R]=t,f&&E>1))for(M=1;M<E;++M)c[R+M]=t;if(u&&(u[R]=i.atomRadius(w),f&&E>1))for(I=u[R]*v/(m?1:.5*E),M=m?1:0;M<E;++M)u[R+M]=I;if(h&&(h[R]=i.atomRadius(S),f&&E>1))for(I=h[R]*v/(m?1:.5*E),M=m?1:0;M<E;++M)h[R+M]=I;R+=f?E:1}),b},Mv.prototype.getBackboneAtomData=function(t){return t=Object.assign({atomSet:this.atomSetCache.__backbone},t),this.getAtomData(t)},Mv.prototype.getBackboneBondData=function(t){return t=Object.assign({bondSet:this.getBackboneBondSet(),bondStore:this.backboneBondStore},t),this.getBondData(t)},Mv.prototype.getRungAtomData=function(t){return t=Object.assign({atomSet:this.atomSetCache.__rung},t),this.getAtomData(t)},Mv.prototype.getRungBondData=function(t){return t=Object.assign({bondSet:this.getRungBondSet(),bondStore:this.rungBondStore},t),this.getBondData(t)},Mv.prototype.getBoundingBox=function(e,i){t.Debug&&cf.time("getBoundingBox"),i=i||new st;var r=1/0,n=1/0,o=1/0,a=-1/0,s=-1/0,c=-1/0;return this.eachAtom(function(t){var e=t.x,i=t.y,u=t.z;e<r&&(r=e),i<n&&(n=i),u<o&&(o=u),e>a&&(a=e),i>s&&(s=i),u>c&&(c=u)},e),i.min.set(r,n,o),i.max.set(a,s,c),t.Debug&&cf.timeEnd("getBoundingBox"),i},Mv.prototype.getPrincipalAxes=function(e){t.Debug&&cf.time("getPrincipalAxes");var i=0,r=new va(3,this.atomCount),n=r.data;return this.eachAtom(function(t){n[i+0]=t.x,n[i+1]=t.y,n[i+2]=t.z,i+=3},e),t.Debug&&cf.timeEnd("getPrincipalAxes"),new Ug(r)},Mv.prototype.atomCenter=function(t){return t?this.getBoundingBox(t).getCenter():this.center.clone()},Mv.prototype.getSequence=function(t){var e=[],i=this.getResidueProxy();return this.eachAtom(function(t){i.index=t.residueIndex,t.index===i.traceAtomIndex&&e.push(i.getResname1())},t),e},Mv.prototype.getAtomIndices=function(t){var e;if(t&&t.string)e=[],this.eachAtom(function(t){e.push(t.index)},t);else{var i={what:{index:!0}};e=this.getAtomData(i).index}return e},Mv.prototype.getChainnameCount=function(t){var e=new Set;return this.eachChain(function(t){t.residueCount&&e.add(t.chainname)},t),e.size},Mv.prototype.updatePosition=function(t){var e=0;this.eachAtom(function(i){i.positionFromArray(t,e),e+=3})},Mv.prototype.refreshPosition=function(){this.getBoundingBox(void 0,this.boundingBox),this.boundingBox.getCenter(this.center),this.spatialHash=new Fa(this.atomStore,this.boundingBox)},Mv.prototype.dispose=function(){this.frames&&(this.frames.length=0),this.boxes&&(this.boxes.length=0),this.bondStore.dispose(),this.backboneBondStore.dispose(),this.rungBondStore.dispose(),this.atomStore.dispose(),this.residueStore.dispose(),this.chainStore.dispose(),this.modelStore.dispose(),delete this.bondStore,delete this.atomStore,delete this.residueStore,delete this.chainStore,delete this.modelStore,delete this.frames,delete this.boxes,delete this.cif,delete this.bondSet,delete this.atomSet},Object.defineProperties(Mv.prototype,Pv);var Tv=function(t,e){var i;"function"==typeof t.eachAtom?i=t.atomCount:t instanceof Float32Array&&(i=t.length/3);var r=new va(3,i),n=new va(3,i);this.coords1t=new va(i,3),this.coords2t=new va(i,3),this.A=new va(3,3),this.W=new va(1,3),this.U=new va(3,3),this.V=new va(3,3),this.VH=new va(3,3),this.R=new va(3,3),this.tmp=new va(3,3),this.c=new va(3,3),this.c.data.set([1,0,0,0,1,0,0,0,-1]),this.prepCoords(t,r),this.prepCoords(e,n),this._superpose(r,n)};Tv.prototype._superpose=function(e,i){this.mean1=Sa(e),this.mean2=Sa(i),Aa(e,this.mean1),Aa(i,this.mean2),ya(this.coords1t,e),ya(this.coords2t,i),ba(this.A,this.coords2t,this.coords1t),Ca(this.A,this.W,this.U,this.V),xa(this.V,this.VH),wa(this.R,this.U,this.VH),_a(this.R)<0&&(t.Debug&&cf.log("R not a right handed system"),wa(this.tmp,this.c,this.VH),wa(this.R,this.U,this.tmp))},Tv.prototype.prepCoords=function(t,e){var i=0,r=e.data;"function"==typeof t.eachAtom?t.eachAtom(function(t){r[i+0]=t.x,r[i+1]=t.y,r[i+2]=t.z,i+=3}):t instanceof Float32Array?r.set(t):cf.warn("prepCoords: input type unknown")},Tv.prototype.transform=function(t){var e;"function"==typeof t.eachAtom?e=t.atomCount:t instanceof Float32Array&&(e=t.length/3);var i=new va(3,e),r=new va(e,3);this.prepCoords(t,i),Aa(i,this.mean1),ba(r,this.R,i),ya(i,r),Ma(i,this.mean2);var n=0,o=i.data;"function"==typeof t.eachAtom?t.eachAtom(function(t){t.x=o[n+0],t.y=o[n+1],t.z=o[n+2],n+=3}):t instanceof Float32Array?t.set(o.subarray(0,3*e)):cf.warn("transform: input type unknown")};var Ev=function(t,e){this.signals={startedRunning:new io,haltedRunning:new io};var i=Object.assign({},e);t.signals.playerChanged.add(function(t){t!==this&&this.pause()},this);var r=dn(t.numframes,1);this.traj=t,this.start=dn(i.start,0),this.end=Math.min(dn(i.end,r-1),r-1),this.step=dn(i.step,Math.ceil((r+1)/100)),this.timeout=dn(i.timeout,50),this.interpolateType=dn(i.interpolateType,""),this.interpolateStep=dn(i.interpolateStep,5),this.mode=dn(i.mode,"loop"),this.direction=dn(i.direction,"forward"),this._stopFlag=!1,this._running=!1,t.signals.gotNumframes.add(function(t){this.end=Math.min(dn(i.end,t-1),t-1)},this)};Ev.prototype._animate=function(){var t;if(this._running=!0,this.traj.inProgress||this._stopFlag||(((t="forward"===this.direction?this.traj.currentFrame+this.step:this.traj.currentFrame-this.step)>=this.end||t<this.start)&&("once"===this.mode?(this.pause(),t="forward"===this.direction?this.end:this.start):t="forward"===this.direction?this.start:this.end),this.interpolateType||this.traj.setFrame(t)),this._stopFlag)this._running=!1;else if(!this.traj.inProgress&&this.interpolateType){var e,i,r;"forward"===this.direction?(e=Math.max(this.start,t-this.step),i=Math.max(this.start,t-2*this.step),r=Math.max(this.start,t-3*this.step)):(e=Math.min(this.end,t+this.step),i=Math.min(this.end,t+2*this.step),r=Math.min(this.end,t+3*this.step)),this._interpolate(t,e,i,r,1/this.interpolateStep,0)}else setTimeout(this._animate.bind(this),this.timeout)},Ev.prototype._interpolate=function(t,e,i,r,n,o){if((o+=n)<=1){var a=Math.round(this.timeout*n);this.traj.setFrameInterpolated(t,e,i,r,o,this.interpolateType,function(){setTimeout(function(){this._interpolate(t,e,i,r,n,o)}.bind(this),a)}.bind(this))}else setTimeout(this._animate.bind(this),0)},Ev.prototype.toggle=function(){this._running?this.pause():this.play()},Ev.prototype.play=function(){if(!this._running){this.traj.player!==this&&this.traj.setPlayer(this);var t=this.traj.currentFrame,e=Math.ceil(t/this.step)*this.step;"forward"===this.direction&&t>=this.end?e=this.start:"backward"===this.direction&&t<=this.start&&(e=this.end),this.traj.setFrame(e),this._stopFlag=!1,this._animate(),this.signals.startedRunning.dispatch()}},Ev.prototype.pause=function(){this._running&&(this._stopFlag=!0,this.signals.haltedRunning.dispatch())},Ev.prototype.stop=function(){this.traj.setFrame(this.start),this.pause()};var Cv=function(t,e,i){this.signals={gotNumframes:new io,frameChanged:new io,selectionChanged:new io,playerChanged:new io};var r=i||{};r.centerPbc=dn(r.centerPbc,!0),r.removePbc=dn(r.removePbc,!0),r.superpose=dn(r.superpose,!0),this.setParameters(r),this.name=t.replace(/^.*[\\\/]/,""),this.selection=new Kd(dn(r.sele,"backbone and not hydrogen")),this.selection.signals.stringChanged.add(function(){this.makeIndices(),this.resetCache()},this),this.setStructure(e),this.setPlayer(new Ev(this)),this.trajPath=t,this.numframes=void 0,this.getNumframes()};Cv.prototype.setStructure=function(t){this.structure=t,this.atomCount=t.atomCount,this.makeAtomIndices(),this.saveInitialStructure(),this.backboneIndices=this.getIndices(new Kd("backbone and not hydrogen")),this.makeIndices(),this.frameCache=[],this.boxCache=[],this.pathCache=[],this.frameCacheSize=0,this.currentFrame=-1},Cv.prototype.saveInitialStructure=function(){var t=0,e=new Float32Array(3*this.atomCount);this.structure.eachAtom(function(i){e[t+0]=i.x,e[t+1]=i.y,e[t+2]=i.z,t+=3}),this.initialStructure=e},Cv.prototype.setSelection=function(t){return this.selection.setString(t),this},Cv.prototype.getIndices=function(t){var e;if(t&&t.test){var i=0,r=t.test;e=[],this.structure.eachAtom(function(t){r(t)&&e.push(i),i+=1})}else e=this.structure.getAtomIndices(this.selection);return e},Cv.prototype.makeIndices=function(){var t=this;this.indices=this.getIndices(this.selection);var e,i,r=3*this.indices.length;this.coords1=new Float32Array(r),this.coords2=new Float32Array(r);var n=this.initialStructure,o=this.coords2;for(e=0;e<r;e+=3)i=3*t.indices[e/3],o[e+0]=n[i+0],o[e+1]=n[i+1],o[e+2]=n[i+2]},Cv.prototype.makeAtomIndices=function(){cf.error("Trajectory.makeAtomIndices not implemented")},Cv.prototype.getNumframes=function(){cf.error("Trajectory.loadFrame not implemented")},Cv.prototype.resetCache=function(){return this.frameCache=[],this.boxCache=[],this.pathCache=[],this.frameCacheSize=0,this.setFrame(this.currentFrame),this},Cv.prototype.setParameters=function(t){var e=t,i=!1;void 0!==e.centerPbc&&e.centerPbc!==this.centerPbc&&(this.centerPbc=e.centerPbc,i=!0),void 0!==e.removePbc&&e.removePbc!==this.removePbc&&(this.removePbc=e.removePbc,i=!0),void 0!==e.superpose&&e.superpose!==this.superpose&&(this.superpose=e.superpose,i=!0),i&&this.resetCache()},Cv.prototype.setFrame=function(t,e){return void 0===t?this:(this.inProgress=!0,t=parseInt(t),-1===t||this.frameCache[t]?this.updateStructure(t,e):this.loadFrame(t,function(){this.updateStructure(t,e)}.bind(this)),this)},Cv.prototype.interpolate=function(t,e,i,r,n,o,a){var s,c=this.frameCache,u=c[t],h=c[e],l=c[i],p=c[r],d=u.length,f=new Float32Array(d);if("spline"===o)for(s=0;s<d;s+=3)f[s+0]=Kn(p[s+0],l[s+0],h[s+0],u[s+0],n,1),f[s+1]=Kn(p[s+1],l[s+1],h[s+1],u[s+1],n,1),f[s+2]=Kn(p[s+2],l[s+2],h[s+2],u[s+2],n,1);else for(s=0;s<d;s+=3)f[s+0]=Zn(h[s+0],u[s+0],n),f[s+1]=Zn(h[s+1],u[s+1],n),f[s+2]=Zn(h[s+2],u[s+2],n);this.structure.updatePosition(f),this.currentFrame=t,this.signals.frameChanged.dispatch(t),"function"==typeof a&&a()},Cv.prototype.setFrameInterpolated=function(t,e,i,r,n,o,a){if(void 0===t)return this;var s=this.frameCache,c=[];return s[r]||c.push(r),s[i]||c.push(i),s[e]||c.push(e),s[t]||c.push(t),c.length?this.loadFrame(c,function(){this.interpolate(t,e,i,r,n,o,a)}.bind(this)):this.interpolate(t,e,i,r,n,o,a),this},Cv.prototype.loadFrame=function(t,e){if(Array.isArray(t)){var i,r=function(t,r){this._loadFrame(t,r),0===i.length()&&"function"==typeof e&&e()}.bind(this);i=new ms(r,t)}else this._loadFrame(t,e)},Cv.prototype._loadFrame=function(t,e){cf.error("Trajectory._loadFrame not implemented",t,e)},Cv.prototype.updateStructure=function(t,e){this._disposed||(-1===t?this.structure.updatePosition(this.initialStructure):this.structure.updatePosition(this.frameCache[t]),this.structure.trajectory={name:this.trajPath,frame:t},"function"==typeof e&&e(),this.currentFrame=t,this.inProgress=!1,this.signals.frameChanged.dispatch(t))},Cv.prototype.getCircularMean=function(t,e,i){return[Ao(e,i[0],3,0,t),Ao(e,i[1],3,1,t),Ao(e,i[2],3,2,t)]},Cv.prototype.doSuperpose=function(t){var e,i,r=this,n=3*this.indices.length,o=this.coords1,a=this.coords2;for(e=0;e<n;e+=3)i=3*r.indices[e/3],o[e+0]=t[i+0],o[e+1]=t[i+1],o[e+2]=t[i+2];new Tv(o,a).transform(t)},Cv.prototype.process=function(t,e,i,r){if(this.setNumframes(r),e){if(this.backboneIndices.length>0&&this.centerPbc){var n=[e[0],e[4],e[8]];gs(i,this.getCircularMean(this.backboneIndices,i,n),n)}this.removePbc&&vs(i,e)}this.indices.length>0&&this.superpose&&this.doSuperpose(i),this.frameCache[t]=i,this.boxCache[t]=e,this.frameCacheSize+=1},Cv.prototype.setNumframes=function(t){t!==this.numframes&&(this.numframes=t,this.signals.gotNumframes.dispatch(t))},Cv.prototype.dispose=function(){this.frameCache=[],this._disposed=!0,this.player&&this.player.stop()},Cv.prototype.setPlayer=function(t){this.player=t,this.signals.playerChanged.dispatch(t)},Cv.prototype.getPath=function(t,e){cf.error("Trajectory.getPath not implemented",t,e)},mf.add("shader/Mesh.vert","#define STANDARD\nuniform float nearClip;\nuniform vec3 clipCenter;\n#if defined( NEAR_CLIP ) || defined( RADIUS_CLIP ) || ( !defined( PICKING ) && !defined( NOLIGHT ) )\nvarying vec3 vViewPosition;\n#endif\n#if defined( RADIUS_CLIP )\nvarying vec3 vClipCenter;\n#endif\n#if defined( PICKING )\n#include unpack_color\nattribute float primitiveId;\nvarying vec3 vPickingColor;\n#elif defined( NOLIGHT )\nvarying vec3 vColor;\n#else\n#include color_pars_vertex\n#ifndef FLAT_SHADED\nvarying vec3 vNormal;\n#endif\n#endif\n#include common\nvoid main(){\n#if defined( PICKING )\nvPickingColor = unpackColor( primitiveId );\n#elif defined( NOLIGHT )\nvColor = color;\n#else\n#include color_vertex\n#include beginnormal_vertex\n#include defaultnormal_vertex\n#ifndef FLAT_SHADED\nvNormal = normalize( transformedNormal );\n#endif\n#endif\n#include begin_vertex\n#include project_vertex\n#if defined( NEAR_CLIP ) || defined( RADIUS_CLIP ) || ( !defined( PICKING ) && !defined( NOLIGHT ) )\nvViewPosition = -mvPosition.xyz;\n#endif\n#if defined( RADIUS_CLIP )\nvClipCenter = -( modelViewMatrix * vec4( clipCenter, 1.0 ) ).xyz;\n#endif\n#include nearclip_vertex\n}"),mf.add("shader/Mesh.frag","#define STANDARD\nuniform vec3 diffuse;\nuniform vec3 emissive;\nuniform float roughness;\nuniform float metalness;\nuniform float opacity;\nuniform float nearClip;\nuniform float clipRadius;\n#if defined( NEAR_CLIP ) || defined( RADIUS_CLIP ) || ( !defined( PICKING ) && !defined( NOLIGHT ) )\nvarying vec3 vViewPosition;\n#endif\n#if defined( RADIUS_CLIP )\nvarying vec3 vClipCenter;\n#endif\n#if defined( PICKING )\nuniform float objectId;\nvarying vec3 vPickingColor;\n#elif defined( NOLIGHT )\nvarying vec3 vColor;\n#else\n#ifndef FLAT_SHADED\nvarying vec3 vNormal;\n#endif\n#include common\n#include color_pars_fragment\n#include fog_pars_fragment\n#include bsdfs\n#include lights_pars\n#include lights_physical_pars_fragment\n#endif\nvoid main(){\n#include nearclip_fragment\n#include radiusclip_fragment\n#if defined( PICKING )\nif( opacity < 0.7 )\ndiscard;\ngl_FragColor = vec4( vPickingColor, objectId );\n#elif defined( NOLIGHT )\ngl_FragColor = vec4( vColor, opacity );\n#else\nvec4 diffuseColor = vec4( diffuse, opacity );\nReflectedLight reflectedLight = ReflectedLight( vec3( 0.0 ), vec3( 0.0 ), vec3( 0.0 ), vec3( 0.0 ) );\nvec3 totalEmissiveLight = emissive;\n#include color_fragment\n#include roughnessmap_fragment\n#include metalnessmap_fragment\n#include normal_flip\n#include normal_fragment\n#include dull_interior_fragment\n#include lights_physical_fragment\n#include lights_template\nvec3 outgoingLight = reflectedLight.directDiffuse + reflectedLight.indirectDiffuse + reflectedLight.directSpecular + reflectedLight.indirectSpecular + totalEmissiveLight;\ngl_FragColor = vec4( outgoingLight, diffuseColor.a );\n#include premultiplied_alpha_fragment\n#include tonemapping_fragment\n#include encodings_fragment\n#include fog_fragment\n#include opaque_back_fragment\n#endif\n}");var Iv={f:1,v2:2,v3:3,c:3},Lv=function(t,e){var i=t||{},r=e||{};this.opaqueBack=dn(r.opaqueBack,!1),this.dullInterior=dn(r.dullInterior,!1),this.side=dn(r.side,"double"),this.opacity=dn(r.opacity,1),this.depthWrite=dn(r.depthWrite,!0),this.clipNear=dn(r.clipNear,0),this.clipRadius=dn(r.clipRadius,0),this.clipCenter=dn(r.clipCenter,new g),this.flatShaded=dn(r.flatShaded,!1),this.background=dn(r.background,!1),this.linewidth=dn(r.linewidth,1),this.wireframe=dn(r.wireframe,!1),this.wireframeLinewidth=dn(r.wireframeLinewidth,1),this.roughness=dn(r.roughness,.4),this.metalness=dn(r.metalness,0),this.diffuse=dn(r.diffuse,16777215),this.forceTransparent=dn(r.forceTransparent,!1),this.geometry=new Ct,this.indexVersion=0,this.wireframeIndexVersion=-1,this.uniforms=Ll.merge([Il.common,{fogColor:{value:null},fogNear:{value:0},fogFar:{value:0},opacity:{value:this.opacity},nearClip:{value:0},clipRadius:{value:this.clipRadius},clipCenter:{value:this.clipCenter}},{emissive:{value:new tt(0)},roughness:{value:this.roughness},metalness:{value:this.metalness}},Il.ambient,Il.lights]),this.uniforms.diffuse.value.set(this.diffuse),this.pickingUniforms={nearClip:{value:0},objectId:{value:0},opacity:{value:this.opacity}},this.group=new Re,this.wireframeGroup=new Re,this.pickingGroup=new Re,this.matrix=dn(r.matrix,new v);var n=i.position||i.position1;this._positionDataSize=n?n.length/3:0,this.addAttributes({position:{type:"v3",value:i.position},color:{type:"c",value:i.color},primitiveId:{type:"f",value:i.primitiveId}}),i.index&&this.initIndex(i.index),this.picking=i.picking,this.makeWireframeGeometry()},Rv={parameters:{},matrix:{},transparent:{},size:{},attributeSize:{},pickable:{},dynamic:{},vertexShader:{},fragmentShader:{}};Rv.parameters.get=function(){return{opaqueBack:{updateShader:!0},dullInterior:{updateShader:!0},side:{updateShader:!0,property:!0},opacity:{uniform:!0},depthWrite:{property:!0},clipNear:{updateShader:!0,property:!0},clipRadius:{updateShader:!0,property:!0,uniform:!0},clipCenter:{uniform:!0},flatShaded:{updateShader:!0},background:{updateShader:!0},linewidth:{property:!0},wireframe:{updateVisibility:!0},roughness:{uniform:!0},metalness:{uniform:!0},diffuse:{uniform:!0},matrix:{}}},Rv.matrix.set=function(t){this.setMatrix(t)},Rv.matrix.get=function(){return this.group.matrix.clone()},Rv.transparent.get=function(){return this.opacity<1||this.forceTransparent},Rv.size.get=function(){return this._positionDataSize},Rv.attributeSize.get=function(){return this.size},Rv.pickable.get=function(){return!!this.picking},Rv.dynamic.get=function(){return!0},Rv.vertexShader.get=function(){},Rv.fragmentShader.get=function(){},Lv.prototype.setMatrix=function(t){bs(this.group,t),bs(this.wireframeGroup,t),bs(this.pickingGroup,t)},Lv.prototype.initIndex=function(t){this.geometry.setIndex(new _t(t,1)),this.geometry.getIndex().setDynamic(this.dynamic)},Lv.prototype.makeMaterial=function(){var t=ys(this.side),e=new ot({uniforms:this.uniforms,vertexShader:"",fragmentShader:"",depthTest:!0,transparent:this.transparent,depthWrite:this.depthWrite,lights:!0,fog:!0,side:t,linewidth:this.linewidth});e.vertexColors=Lu,e.extensions.derivatives=this.flatShaded,e.extensions.fragDepth=this.isImpostor,e.clipNear=this.clipNear;var i=new ot({uniforms:this.uniforms,vertexShader:"",fragmentShader:"",depthTest:!0,transparent:this.transparent,depthWrite:this.depthWrite,lights:!1,fog:!0,side:t,linewidth:this.linewidth});i.vertexColors=Lu,i.clipNear=this.clipNear;var r=new ot({uniforms:this.pickingUniforms,vertexShader:"",fragmentShader:"",depthTest:!0,transparent:!1,depthWrite:this.depthWrite,lights:!1,fog:!1,side:t,linewidth:this.linewidth,blending:Ru});r.vertexColors=Lu,r.extensions.fragDepth=this.isImpostor,r.clipNear=this.clipNear,this.material=e,this.wireframeMaterial=i,this.pickingMaterial=r,this.updateShader()},Lv.prototype.makeWireframeGeometry=function(){this.makeWireframeIndex();var t=this.geometry,e=this.wireframeIndex,i=new Ct;i.attributes=t.attributes,e&&(i.setIndex(new _t(e,1).setDynamic(this.dynamic)),i.setDrawRange(0,this.wireframeIndexCount)),this.wireframeGeometry=i},Lv.prototype.makeWireframeIndex=function(){function t(t,i){if(t>i){var r=t;t=i,i=r}var n=e[t];return void 0===n?(e[t]=[i],!0):!n.includes(i)&&(n.push(i),!0)}var e=[],i=this.geometry,r=i.index;if(this.wireframe)if(r){var n=r.array,o=n.length;i.drawRange.count!==1/0&&(o=i.drawRange.count);var a;a=this.wireframeIndex&&this.wireframeIndex.length>2*o?this.wireframeIndex:Cn(2*o,i.attributes.position.count);var s=0;e.length=0;for(var c=0;c<o;c+=3){var u=n[c+0],h=n[c+1],l=n[c+2];t(u,h)&&(a[s+0]=u,a[s+1]=h,s+=2),t(h,l)&&(a[s+0]=h,a[s+1]=l,s+=2),t(l,u)&&(a[s+0]=l,a[s+1]=u,s+=2)}this.wireframeIndex=a,this.wireframeIndexCount=s,this.wireframeIndexVersion=this.indexVersion}else{var p,d=i.attributes.position.count;p=this.wireframeIndex&&this.wireframeIndex.length>2*d?this.wireframeIndex:Cn(2*d,d);for(var f=0,m=0;f<d;f+=3)p[m+0]=f,p[m+1]=f+1,p[m+2]=f+1,p[m+3]=f+2,p[m+4]=f+2,p[m+5]=f,m+=6;this.wireframeIndex=p,this.wireframeIndexCount=2*d,this.wireframeIndexVersion=this.indexVersion}else this.wireframeIndex=new Uint16Array(0),this.wireframeIndexCount=0},Lv.prototype.updateWireframeIndex=function(){if(this.wireframeGeometry.setDrawRange(0,1/0),this.wireframeIndexVersion<this.indexVersion&&this.makeWireframeIndex(),this.wireframeIndex.length>this.wireframeGeometry.index.array.length)this.wireframeGeometry.setIndex(new _t(this.wireframeIndex,1).setDynamic(this.dynamic));else{var t=this.wireframeGeometry.getIndex();t.set(this.wireframeIndex),t.needsUpdate=this.wireframeIndexCount>0,t.updateRange.count=this.wireframeIndexCount}this.wireframeGeometry.setDrawRange(0,this.wireframeIndexCount)},Lv.prototype.getRenderOrder=function(){var t=0;return this.isText?t=1:this.transparent&&(t=this.isSurface?3:2),t},Lv.prototype._getMesh=function(t){this.material||this.makeMaterial();var e,i=this.geometry,r=this[t];return this.isLine?e=new Ee(i,r):this.isPoint?(e=new Le(i,r),this.sortParticles&&(e.sortParticles=!0)):e=new It(i,r),e.frustumCulled=!1,e.renderOrder=this.getRenderOrder(),e},Lv.prototype.getMesh=function(){return this._getMesh("material")},Lv.prototype.getWireframeMesh=function(){var t;return this.material||this.makeMaterial(),this.wireframeGeometry||this.makeWireframeGeometry(),t=new Ee(this.wireframeGeometry,this.wireframeMaterial),t.frustumCulled=!1,t.renderOrder=this.getRenderOrder(),t},Lv.prototype.getPickingMesh=function(){return this._getMesh("pickingMaterial")},Lv.prototype.getShader=function(t,e){return wo(t,this.getDefines(e))},Lv.prototype.getVertexShader=function(t){return this.getShader(this.vertexShader,t)},Lv.prototype.getFragmentShader=function(t){return this.getShader(this.fragmentShader,t)},Lv.prototype.getDefines=function(t){var e={};return this.clipNear&&(e.NEAR_CLIP=1),this.clipRadius&&(e.RADIUS_CLIP=1),"picking"===t?e.PICKING=1:(("background"===t||this.background)&&(e.NOLIGHT=1),this.flatShaded&&(e.FLAT_SHADED=1),this.opaqueBack&&(e.OPAQUE_BACK=1),this.dullInterior&&(e.DULL_INTERIOR=1)),e},Lv.prototype.getParameters=function(){var t=this,e={};for(var i in t.parameters)e[i]=t[i];return e},Lv.prototype.addUniforms=function(t){this.uniforms=Ll.merge([this.uniforms,t]),this.pickingUniforms=Ll.merge([this.pickingUniforms,t])},Lv.prototype.addAttributes=function(t){var e=this;for(var i in t){var r=void 0,n=t[i],o=e.attributeSize*Iv[n.type];n.value?(o!==n.value.length&&cf.error("attribute value has wrong length",i),r=n.value):r=En("float32",o),e.geometry.addAttribute(i,new _t(r,Iv[n.type]).setDynamic(e.dynamic))}},Lv.prototype.updateRenderOrder=function(){function t(t){t.renderOrder=e}var e=this.getRenderOrder();this.group.children.forEach(t),this.pickingGroup&&this.pickingGroup.children.forEach(t)},Lv.prototype.updateShader=function(){var t=this.material,e=this.wireframeMaterial,i=this.pickingMaterial;t.vertexShader=this.getVertexShader(),t.fragmentShader=this.getFragmentShader(),t.needsUpdate=!0,e.vertexShader=this.getShader("Line.vert"),e.fragmentShader=this.getShader("Line.frag"),e.needsUpdate=!0,i.vertexShader=this.getVertexShader("picking"),i.fragmentShader=this.getFragmentShader("picking"),i.needsUpdate=!0},Lv.prototype.setParameters=function(t){var e=this;if(t){var i=t,r=this.parameters,n={},o={},a=!1,s=!1;for(var c in i){var u=i[c];void 0!==u&&(void 0!==r[c]&&(e[c]=u,r[c].property&&(!0!==r[c].property?n[r[c].property]=u:n[c]=u),r[c].uniform&&(!0!==r[c].uniform?o[r[c].uniform]=u:o[c]=u),r[c].updateShader&&(a=!0),r[c].updateVisibility&&(s=!0),e.dynamic&&"wireframe"===c&&!0===u&&e.updateWireframeIndex(),"flatShaded"===c&&(e.material.extensions.derivatives=e.flatShaded),"forceTransparent"===c&&(n.transparent=e.transparent)))}this.setProperties(n),this.setUniforms(o),a&&this.updateShader(),s&&this.setVisibility(this.visible)}},Lv.prototype.setAttributes=function(t){var e=this,i=this.geometry,r=i.attributes;for(var n in t)if("picking"!==n){var o=t[n],a=o.length;if("index"===n){var s=i.getIndex();i.setDrawRange(0,1/0),a>s.array.length?i.setIndex(new _t(o,1).setDynamic(e.dynamic)):(s.set(o),s.needsUpdate=a>0,s.updateRange.count=a,i.setDrawRange(0,a)),e.indexVersion++,e.wireframe&&e.updateWireframeIndex()}else{var c=r[n];a>c.array.length?i.addAttribute(n,new _t(o,c.itemSize).setDynamic(e.dynamic)):(r[n].set(o),r[n].needsUpdate=a>0,r[n].updateRange.count=a)}}},Lv.prototype.setUniforms=function(t){var e=this;if(t){var i=this.material.uniforms,r=this.wireframeMaterial.uniforms,n=this.pickingMaterial.uniforms;for(var o in t)"opacity"===o&&e.setProperties({transparent:e.transparent}),void 0!==i[o]&&(i[o].value.isVector3?i[o].value.copy(t[o]):i[o].value.set?i[o].value.set(t[o]):i[o].value=t[o]),void 0!==r[o]&&(r[o].value.isVector3?r[o].value.copy(t[o]):r[o].value.set?r[o].value.set(t[o]):r[o].value=t[o]),void 0!==n[o]&&(n[o].value.isVector3?n[o].value.copy(t[o]):n[o].value.set?n[o].value.set(t[o]):n[o].value=t[o])}},Lv.prototype.setProperties=function(t){var e=this;if(t){var i=this.material,r=this.wireframeMaterial,n=this.pickingMaterial;for(var o in t){var a=t[o];"transparent"===o?e.updateRenderOrder():"side"===o&&(a=ys(a)),void 0!==i[o]&&(i[o]=a),void 0!==r[o]&&(r[o]=a),void 0!==n[o]&&(n[o]=a)}i.needsUpdate=!0,r.needsUpdate=!0,n.needsUpdate=!0}},Lv.prototype.setVisibility=function(t){this.visible=t,this.wireframe?(this.group.visible=!1,this.wireframeGroup.visible=t,this.pickable&&(this.pickingGroup.visible=!1)):(this.group.visible=t,this.wireframeGroup.visible=!1,this.pickable&&(this.pickingGroup.visible=t))},Lv.prototype.dispose=function(){this.material&&this.material.dispose(),this.wireframeMaterial&&this.wireframeMaterial.dispose(),this.pickingMaterial&&this.pickingMaterial.dispose(),this.geometry.dispose(),this.wireframeGeometry&&this.wireframeGeometry.dispose()},Object.defineProperties(Lv.prototype,Rv);var Ov=function(t){function e(e,i){var r=e||{};!r.primitiveId&&r.position&&(r.primitiveId=Co(r.position.length/3)),t.call(this,r,i),this.addAttributes({normal:{type:"v3",value:r.normal}}),void 0===r.normal&&this.geometry.computeVertexNormals()}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={vertexShader:{},fragmentShader:{}};return i.vertexShader.get=function(){return"Mesh.vert"},i.fragmentShader.get=function(){return"Mesh.frag"},Object.defineProperties(e.prototype,i),e}(Lv),Dv=new v,Nv=new ut,kv=function(t){function e(e,i,r){var n,o=e||{},a=i||{},s=r.attributes.position.array,c=r.attributes.normal.array,u=r.index?r.index.array:void 0,h=o.position.length/3,l=s.length/3,p=h*l,d=new Float32Array(3*p),f=new Float32Array(3*p),m=new Float32Array(3*p);u&&(n=Cn(h*u.length,p)),t.call(this,{position:d,color:m,index:n,normal:f,primitiveId:o.primitiveId||Io(h,l),picking:o.picking},a),this.setAttributes(o),this.geoPosition=s,this.geoNormal=c,this.geoIndex=u,this.positionCount=h,this.geoPositionCount=l,this.transformedGeoPosition=new Float32Array(3*l),this.transformedGeoNormal=new Float32Array(3*l),this.meshPosition=d,this.meshColor=m,this.meshIndex=n,this.meshNormal=f,this.meshIndex=n,this.makeIndex()}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={updateNormals:{}};return e.prototype.applyPositionTransform=function(){},e.prototype.setAttributes=function(t,e){var i,r,n,o,a,s,c,u,h,l=this,p=this.geometry.attributes,d=this.updateNormals;t.position&&(i=t.position,n=this.geoPosition,c=this.meshPosition,a=this.transformedGeoPosition,p.position.needsUpdate=!0,(d||e)&&(o=this.geoNormal,h=this.meshNormal,s=this.transformedGeoNormal,p.normal.needsUpdate=!0)),t.color&&(r=t.color,u=this.meshColor,p.color.needsUpdate=!0);for(var f=this.positionCount,m=this.geoPositionCount,g=0;g<f;++g){var v=void 0,y=void 0,b=g*m*3,x=3*g;if(i&&(a.set(n),Dv.makeTranslation(i[x],i[x+1],i[x+2]),l.applyPositionTransform(Dv,g,x),Jo(Dv.elements,a),c.set(a,b),d?(s.set(o),Nv.getNormalMatrix(Dv),ta(Nv.elements,s),h.set(s,b)):e&&h.set(o,b)),r)for(v=0;v<m;++v)u[y=b+3*v]=r[x],u[y+1]=r[x+1],u[y+2]=r[x+2]}},e.prototype.makeIndex=function(){var t=this.geoIndex,e=this.meshIndex;if(t)for(var i=this.positionCount,r=this.geoPositionCount,n=3*(t.length/3),o=0;o<i;++o){var a=o*n,s=a+n;e.set(t,a);for(var c=a;c<s;++c)e[c]+=o*r}},i.updateNormals.get=function(){return!1},Object.defineProperties(e.prototype,i),e}(Ov),Bv=new g,Fv=function(t){function e(e,i){var r=i||{},n=new He(1,dn(r.sphereDetail,1));t.call(this,e,r,n),this.setAttributes(e,!0)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.applyPositionTransform=function(t,e){var i=this._radius[e];Bv.set(i,i,i),t.scale(Bv)},e.prototype.setAttributes=function(e,i){e.radius&&(this._radius=e.radius),t.prototype.setAttributes.call(this,e,i)},e}(kv);mf.add("shader/SphereImpostor.vert","uniform mat4 projectionMatrixInverse;\nuniform float nearClip;\nvarying float vRadius;\nvarying float vRadiusSq;\nvarying vec3 vPoint;\nvarying vec3 vPointViewPosition;\nattribute vec2 mapping;\nattribute float radius;\n#ifdef PICKING\n#include unpack_color\nattribute float primitiveId;\nvarying vec3 vPickingColor;\n#else\n#include color_pars_vertex\n#endif\n#include matrix_scale\nconst mat4 D = mat4(\n1.0, 0.0, 0.0, 0.0,\n0.0, 1.0, 0.0, 0.0,\n0.0, 0.0, 1.0, 0.0,\n0.0, 0.0, 0.0, -1.0\n);\nmat4 transpose( in mat4 inMatrix ) {\nvec4 i0 = inMatrix[0];\nvec4 i1 = inMatrix[1];\nvec4 i2 = inMatrix[2];\nvec4 i3 = inMatrix[3];\nmat4 outMatrix = mat4(\nvec4(i0.x, i1.x, i2.x, i3.x),\nvec4(i0.y, i1.y, i2.y, i3.y),\nvec4(i0.z, i1.z, i2.z, i3.z),\nvec4(i0.w, i1.w, i2.w, i3.w)\n);\nreturn outMatrix;\n}\nvoid ComputePointSizeAndPositionInClipCoordSphere(){\nvec2 xbc;\nvec2 ybc;\nmat4 T = mat4(\nradius, 0.0, 0.0, 0.0,\n0.0, radius, 0.0, 0.0,\n0.0, 0.0, radius, 0.0,\nposition.x, position.y, position.z, 1.0\n);\nmat4 R = transpose( projectionMatrix * modelViewMatrix * T );\nfloat A = dot( R[ 3 ], D * R[ 3 ] );\nfloat B = -2.0 * dot( R[ 0 ], D * R[ 3 ] );\nfloat C = dot( R[ 0 ], D * R[ 0 ] );\nxbc[ 0 ] = ( -B - sqrt( B * B - 4.0 * A * C ) ) / ( 2.0 * A );\nxbc[ 1 ] = ( -B + sqrt( B * B - 4.0 * A * C ) ) / ( 2.0 * A );\nfloat sx = abs( xbc[ 0 ] - xbc[ 1 ] ) * 0.5;\nA = dot( R[ 3 ], D * R[ 3 ] );\nB = -2.0 * dot( R[ 1 ], D * R[ 3 ] );\nC = dot( R[ 1 ], D * R[ 1 ] );\nybc[ 0 ] = ( -B - sqrt( B * B - 4.0 * A * C ) ) / ( 2.0 * A );\nybc[ 1 ] = ( -B + sqrt( B * B - 4.0 * A * C ) ) / ( 2.0 * A );\nfloat sy = abs( ybc[ 0 ] - ybc[ 1 ] ) * 0.5;\ngl_Position.xy = vec2( 0.5 * ( xbc.x + xbc.y ), 0.5 * ( ybc.x + ybc.y ) );\ngl_Position.xy -= mapping * vec2( sx, sy );\ngl_Position.xy *= gl_Position.w;\n}\nvoid main(void){\n#ifdef PICKING\nvPickingColor = unpackColor( primitiveId );\n#else\n#include color_vertex\n#endif\nvRadius = radius * matrixScale( modelViewMatrix );\nvec4 mvPosition = modelViewMatrix * vec4( position, 1.0 );\nmvPosition.z -= vRadius;\ngl_Position = projectionMatrix * vec4( mvPosition.xyz, 1.0 );\nComputePointSizeAndPositionInClipCoordSphere();\nvRadiusSq = vRadius * vRadius;\nvec4 vPoint4 = projectionMatrixInverse * gl_Position;\nvPoint = vPoint4.xyz / vPoint4.w;\nvPointViewPosition = -mvPosition.xyz / mvPosition.w;\n}"),mf.add("shader/SphereImpostor.frag","#define STANDARD\n#define IMPOSTOR\nuniform vec3 diffuse;\nuniform vec3 emissive;\nuniform float roughness;\nuniform float metalness;\nuniform float opacity;\nuniform float nearClip;\nuniform mat4 projectionMatrix;\nuniform float ortho;\nvarying float vRadius;\nvarying float vRadiusSq;\nvarying vec3 vPoint;\nvarying vec3 vPointViewPosition;\n#ifdef PICKING\nuniform float objectId;\nvarying vec3 vPickingColor;\n#else\n#include common\n#include color_pars_fragment\n#include fog_pars_fragment\n#include bsdfs\n#include lights_pars\n#include lights_physical_pars_fragment\n#endif\nbool flag2 = false;\nbool interior = false;\nvec3 cameraPos;\nvec3 cameraNormal;\nfloat calcDepth( in vec3 cameraPos ){\nvec2 clipZW = cameraPos.z * projectionMatrix[2].zw + projectionMatrix[3].zw;\nreturn 0.5 + 0.5 * clipZW.x / clipZW.y;\n}\nfloat calcClip( vec3 cameraPos ){\nreturn dot( vec4( cameraPos, 1.0 ), vec4( 0.0, 0.0, 1.0, nearClip - 0.5 ) );\n}\nbool Impostor( out vec3 cameraPos, out vec3 cameraNormal ){\nvec3 cameraSpherePos = -vPointViewPosition;\ncameraSpherePos.z += vRadius;\nvec3 rayOrigin = mix( vec3( 0.0, 0.0, 0.0 ), vPoint, ortho );\nvec3 rayDirection = mix( normalize( vPoint ), vec3( 0.0, 0.0, 1.0 ), ortho );\nvec3 cameraSphereDir = mix( cameraSpherePos, rayOrigin - cameraSpherePos, ortho );\nfloat B = dot( rayDirection, cameraSphereDir );\nfloat det = B * B + vRadiusSq - dot( cameraSphereDir, cameraSphereDir );\nif( det < 0.0 ){\ndiscard;\nreturn false;\n}else{\nfloat sqrtDet = sqrt( det );\nfloat posT = mix( B + sqrtDet, B + sqrtDet, ortho );\nfloat negT = mix( B - sqrtDet, sqrtDet - B, ortho );\ncameraPos = rayDirection * negT + rayOrigin;\n#ifdef NEAR_CLIP\nif( calcDepth( cameraPos ) <= 0.0 ){\ncameraPos = rayDirection * posT + rayOrigin;\ninterior = true;\nreturn false;\n}else if( calcClip( cameraPos ) > 0.0 ){\ncameraPos = rayDirection * posT + rayOrigin;\ninterior = true;\nflag2 = true;\nreturn false;\n}else{\ncameraNormal = normalize( cameraPos - cameraSpherePos );\n}\n#else\nif( calcDepth( cameraPos ) <= 0.0 ){\ncameraPos = rayDirection * posT + rayOrigin;\ninterior = true;\nreturn false;\n}else{\ncameraNormal = normalize( cameraPos - cameraSpherePos );\n}\n#endif\nreturn true;\n}\nreturn false;\n}\nvoid main(void){\nbool flag = Impostor( cameraPos, cameraNormal );\n#ifdef NEAR_CLIP\nif( calcClip( cameraPos ) > 0.0 )\ndiscard;\n#endif\ngl_FragDepthEXT = calcDepth( cameraPos );\nif( !flag ){\n#ifdef NEAR_CLIP\nif( flag2 ){\ngl_FragDepthEXT = max( 0.0, calcDepth( vec3( - ( nearClip - 0.5 ) ) ) + ( 0.0000001 / vRadius ) );\n}else if( gl_FragDepthEXT >= 0.0 ){\ngl_FragDepthEXT = 0.0 + ( 0.0000001 / vRadius );\n}\n#else\nif( gl_FragDepthEXT >= 0.0 ){\ngl_FragDepthEXT = 0.0 + ( 0.0000001 / vRadius );\n}\n#endif\n}\nif (gl_FragDepthEXT < 0.0)\ndiscard;\nif (gl_FragDepthEXT > 1.0)\ndiscard;\n#ifdef PICKING\ngl_FragColor = vec4( vPickingColor, objectId );\n#else\nvec3 vNormal = cameraNormal;\nvec3 vViewPosition = -cameraPos;\nvec4 diffuseColor = vec4( diffuse, opacity );\nReflectedLight reflectedLight = ReflectedLight( vec3( 0.0 ), vec3( 0.0 ), vec3( 0.0 ), vec3( 0.0 ) );\nvec3 totalEmissiveLight = emissive;\n#include color_fragment\n#include roughnessmap_fragment\n#include metalnessmap_fragment\n#include normal_flip\n#include normal_fragment\nif( interior ){\nnormal = vec3( 0.0, 0.0, 0.4 );\n}\n#include lights_physical_fragment\n#include lights_template\nvec3 outgoingLight = reflectedLight.directDiffuse + reflectedLight.indirectDiffuse + reflectedLight.directSpecular + reflectedLight.indirectSpecular + totalEmissiveLight;\ngl_FragColor = vec4( outgoingLight, diffuseColor.a );\n#include premultiplied_alpha_fragment\n#include tonemapping_fragment\n#include encodings_fragment\n#include fog_fragment\n#endif\n}");var zv=function(t){function e(e,i){t.call(this,e,i),this.index=Cn(this.indexSize,this.attributeSize),this.makeIndex(),this.initIndex(this.index,1),this.addAttributes({mapping:{type:this.mappingType,value:null}}),this.setAttributes({primitiveId:Co(this.size)})}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={attributeSize:{},indexSize:{},mapping:{},mappingIndices:{},mappingIndicesSize:{},mappingType:{},mappingSize:{},mappingItemSize:{}};return i.attributeSize.get=function(){return this.size*this.mappingSize},i.indexSize.get=function(){return this.size*this.mappingIndicesSize},i.mapping.get=function(){},i.mappingIndices.get=function(){},i.mappingIndicesSize.get=function(){},i.mappingType.get=function(){},i.mappingSize.get=function(){},i.mappingItemSize.get=function(){},e.prototype.addAttributes=function(e){var i={};for(var r in e){var n=e[r];i[r]={type:n.type,value:null}}t.prototype.addAttributes.call(this,i)},e.prototype.getAttributeIndex=function(t){return 3*t*this.mappingSize},e.prototype.setAttributes=function(t){t&&!t.position&&t.position1&&t.position2&&(t.position=Mo(t.position1,t.position2));var e,i,r,n,o,a,s,c=this.size,u=this.mappingSize,h=this.geometry.attributes;for(var l in t)if("index"!==l&&"picking"!==l){i=t[l],r=(e=h[l]).itemSize,n=e.array;for(var p=0;p<c;++p){a=(o=p*r)*u;for(var d=0;d<u;++d){s=a+r*d;for(var f=0;f<r;++f)n[s+f]=i[o+f]}}e.needsUpdate=!0}},e.prototype.makeMapping=function(){for(var t=this.size,e=this.mapping,i=this.mappingSize,r=this.mappingItemSize,n=this.geometry.attributes.mapping.array,o=0;o<t;o++)n.set(e,o*r*i)},e.prototype.makeIndex=function(){for(var t,e,i=this.size,r=this.mappingSize,n=this.mappingIndices,o=this.mappingIndicesSize,a=this.index,s=0;s<i;s++){t=s*o,e=s*r,a.set(n,t);for(var c=0;c<o;++c)a[t+c]+=e}},Object.defineProperties(e.prototype,i),e}(Lv),Uv=new Float32Array([-1,1,-1,-1,1,1,1,-1]),jv=new Uint16Array([0,1,2,1,3,2]),Gv=function(t){function e(){t.apply(this,arguments)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={mapping:{},mappingIndices:{},mappingIndicesSize:{},mappingType:{},mappingSize:{},mappingItemSize:{}};return i.mapping.get=function(){return Uv},i.mappingIndices.get=function(){return jv},i.mappingIndicesSize.get=function(){return 6},i.mappingType.get=function(){return"v2"},i.mappingSize.get=function(){return 4},i.mappingItemSize.get=function(){return 2},Object.defineProperties(e.prototype,i),e}(zv),Vv=function(t){function e(e,i){t.call(this,e,i),this.addUniforms({projectionMatrixInverse:{value:new v},ortho:{value:0}}),this.addAttributes({radius:{type:"f",value:null}}),this.setAttributes(e),this.makeMapping()}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={isImpostor:{},vertexShader:{},fragmentShader:{}};return i.isImpostor.get=function(){return!0},i.vertexShader.get=function(){return"SphereImpostor.vert"},i.fragmentShader.get=function(){return"SphereImpostor.frag"},Object.defineProperties(e.prototype,i),e}(Gv),$v=function(t,e){return!sf||e&&e.disableImpostor?new Fv(t,e):new Vv(t,e)},Hv=new g,Wv=new g,Xv=new g,qv=new g(0,0,0),Yv=function(t){function e(e,i){var r=i||{},n=new He(1,dn(r.sphereDetail,2));t.call(this,e,r,n),this.setAttributes(e,!0)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={updateNormals:{}};return e.prototype.applyPositionTransform=function(t,e,i){Wv.fromArray(this._majorAxis,i),Xv.fromArray(this._minorAxis,i),t.lookAt(qv,Wv,Xv),Hv.set(this._radius[e],Xv.length(),Wv.length()),t.scale(Hv)},e.prototype.setAttributes=function(e,i){e.radius&&(this._radius=e.radius),e.majorAxis&&(this._majorAxis=e.majorAxis),e.minorAxis&&(this._minorAxis=e.minorAxis),t.prototype.setAttributes.call(this,e,i)},i.updateNormals.get=function(){return!0},Object.defineProperties(e.prototype,i),e}(kv),Zv=function(t,e){return new Yv(t,e)},Kv=new g,Qv=new g,Jv=new g,ty=new g(0,1,0),ey=function(t){function e(e,i){var r=e||{},n=i||{},o=dn(n.radialSegments,10),a=dn(n.openEnded,!0),s=(new v).makeRotationX(Math.PI/2),c=new fi(1,1,1,o,1,a);c.applyMatrix(s);var u=r.position1.length,h=r.radius.length,l=c.attributes.position.array.length/3,p=u/3,d=new Float32Array(2*p*l);Io(p,l,0,d),Io(p,l,p*l,d);var f=new Float32Array(2*u),m=new Float32Array(2*u);t.call(this,{position:f,color:m,primitiveId:d,picking:r.picking},n,c),this.__center=new Float32Array(u),this._position=f,this._color=m,this._from=new Float32Array(2*u),this._to=new Float32Array(2*u),this._radius=new Float32Array(2*h),this.setAttributes(r,!0)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={updateNormals:{}};return e.prototype.applyPositionTransform=function(t,e,i){Qv.fromArray(this._from,i),Jv.fromArray(this._to,i),t.lookAt(Qv,Jv,ty);var r=this._radius[e];Kv.set(r,r,Qv.distanceTo(Jv)),t.scale(Kv)},e.prototype.setAttributes=function(e,i){var r={};e.position1&&e.position2&&(Mo(e.position1,e.position2,this.__center),Mo(e.position1,this.__center,this._position),Mo(this.__center,e.position2,this._position,e.position1.length),this._from.set(e.position1),this._from.set(this.__center,e.position1.length),this._to.set(this.__center),this._to.set(e.position2,this.__center.length),r.position=this._position),e.color&&e.color2&&(this._color.set(e.color),this._color.set(e.color2,e.color.length),r.color=this._color),e.radius&&(this._radius.set(e.radius),this._radius.set(e.radius,e.radius.length),r.radius=this._radius),t.prototype.setAttributes.call(this,r,i)},i.updateNormals.get=function(){return!0},Object.defineProperties(e.prototype,i),e}(kv);mf.add("shader/CylinderImpostor.vert","\nattribute vec3 mapping;\nattribute vec3 position1;\nattribute vec3 position2;\nattribute float radius;\nvarying vec3 axis;\nvarying vec4 base_radius;\nvarying vec4 end_b;\nvarying vec3 U;\nvarying vec3 V;\nvarying vec4 w;\n#ifdef PICKING\n#include unpack_color\nattribute float primitiveId;\nvarying vec3 vPickingColor;\n#else\nattribute vec3 color2;\nvarying vec3 vColor1;\nvarying vec3 vColor2;\n#endif\nuniform mat4 modelViewMatrixInverse;\nuniform float ortho;\n#include matrix_scale\nvoid main(){\n#ifdef PICKING\nvPickingColor = unpackColor( primitiveId );\n#else\nvColor1 = color;\nvColor2 = color2;\n#endif\nbase_radius.w = radius * matrixScale( modelViewMatrix );\nvec3 center = position;\nvec3 dir = normalize( position2 - position1 );\nfloat ext = length( position2 - position1 ) / 2.0;\nvec3 cam_dir;\nif( ortho == 0.0 ){\ncam_dir = ( modelViewMatrixInverse * vec4( 0, 0, 0, 1 ) ).xyz - center;\n}else{\ncam_dir = ( modelViewMatrixInverse * vec4( 0, 0, 1, 0 ) ).xyz;\n}\ncam_dir = normalize( cam_dir );\nvec3 ldir;\nfloat b = dot( cam_dir, dir );\nend_b.w = b;\nif( b < 0.0 )\nldir = -ext * dir;\nelse\nldir = ext * dir;\nvec3 left = normalize( cross( cam_dir, ldir ) );\nleft = radius * left;\nvec3 up = radius * normalize( cross( left, ldir ) );\naxis = normalize( normalMatrix * ldir );\nU = normalize( normalMatrix * up );\nV = normalize( normalMatrix * left );\nvec4 base4 = modelViewMatrix * vec4( center - ldir, 1.0 );\nbase_radius.xyz = base4.xyz / base4.w;\nvec4 top_position = modelViewMatrix * vec4( center + ldir, 1.0 );\nvec4 end4 = top_position;\nend_b.xyz = end4.xyz / end4.w;\nw = modelViewMatrix * vec4(\ncenter + mapping.x*ldir + mapping.y*left + mapping.z*up, 1.0\n);\ngl_Position = projectionMatrix * w;\ngl_Position.z = 0.99;\n}"),mf.add("shader/CylinderImpostor.frag","#define STANDARD\n#define IMPOSTOR\nuniform vec3 diffuse;\nuniform vec3 emissive;\nuniform float roughness;\nuniform float metalness;\nuniform float opacity;\nuniform float nearClip;\nuniform mat4 projectionMatrix;\nuniform float ortho;\nvarying vec3 axis;\nvarying vec4 base_radius;\nvarying vec4 end_b;\nvarying vec3 U;\nvarying vec3 V;\nvarying vec4 w;\n#ifdef PICKING\nuniform float objectId;\nvarying vec3 vPickingColor;\n#else\nvarying vec3 vColor1;\nvarying vec3 vColor2;\n#include common\n#include fog_pars_fragment\n#include bsdfs\n#include lights_pars\n#include lights_physical_pars_fragment\n#endif\nbool interior = false;\nfloat distSq3( vec3 v3a, vec3 v3b ){\nreturn (\n( v3a.x - v3b.x ) * ( v3a.x - v3b.x ) +\n( v3a.y - v3b.y ) * ( v3a.y - v3b.y ) +\n( v3a.z - v3b.z ) * ( v3a.z - v3b.z )\n);\n}\nfloat calcDepth( in vec3 cameraPos ){\nvec2 clipZW = cameraPos.z * projectionMatrix[2].zw + projectionMatrix[3].zw;\nreturn 0.5 + 0.5 * clipZW.x / clipZW.y;\n}\nfloat calcClip( vec3 cameraPos ){\nreturn dot( vec4( cameraPos, 1.0 ), vec4( 0.0, 0.0, 1.0, nearClip - 0.5 ) );\n}\nvoid main(){\nvec3 point = w.xyz / w.w;\nvec3 base = base_radius.xyz;\nfloat vRadius = base_radius.w;\nvec3 end = end_b.xyz;\nfloat b = end_b.w;\nvec3 end_cyl = end;\nvec3 surface_point = point;\nvec3 ray_target = surface_point;\nvec3 ray_origin = vec3(0.0);\nvec3 ray_direction = mix(normalize(ray_origin - ray_target), vec3(0.0, 0.0, 1.0), ortho);\nmat3 basis = mat3( U, V, axis );\nvec3 diff = ray_target - 0.5 * (base + end_cyl);\nvec3 P = diff * basis;\nfloat dz = dot( axis, ray_direction );\nfloat radius2 = vRadius*vRadius;\nvec3 D = vec3(dot(U, ray_direction),\ndot(V, ray_direction),\ndz);\nfloat a0 = P.x*P.x + P.y*P.y - radius2;\nfloat a1 = P.x*D.x + P.y*D.y;\nfloat a2 = D.x*D.x + D.y*D.y;\nfloat d = a1*a1 - a0*a2;\nif (d < 0.0)\ndiscard;\nfloat dist = (-a1 + sqrt(d)) / a2;\nvec3 new_point = ray_target + dist * ray_direction;\nvec3 tmp_point = new_point - base;\nvec3 _normal = normalize( tmp_point - axis * dot(tmp_point, axis) );\nray_origin = mix( ray_origin, surface_point, ortho );\nfloat front_cap_test = dot( tmp_point, axis );\nfloat end_cap_test = dot((new_point - end_cyl), axis);\n#ifndef CAP\nvec3 new_point2 = ray_target + ( (-a1 - sqrt(d)) / a2 ) * ray_direction;\nvec3 tmp_point2 = new_point2 - base;\n#endif\nif (front_cap_test < 0.0)\n{\nfloat dNV = dot(-axis, ray_direction);\nif (dNV < 0.0)\ndiscard;\nfloat near = dot(-axis, (base)) / dNV;\nvec3 front_point = ray_direction * near + ray_origin;\nif (dot(front_point - base, front_point-base) > radius2)\ndiscard;\n#ifdef CAP\nnew_point = front_point;\n_normal = axis;\n#else\nnew_point = ray_target + ( (-a1 - sqrt(d)) / a2 ) * ray_direction;\ndNV = dot(-axis, ray_direction);\nnear = dot(axis, end_cyl) / dNV;\nnew_point2 = ray_direction * near + ray_origin;\nif (dot(new_point2 - end_cyl, new_point2-base) < radius2)\ndiscard;\ninterior = true;\n#endif\n}\nif( end_cap_test > 0.0 )\n{\nfloat dNV = dot(axis, ray_direction);\nif (dNV < 0.0)\ndiscard;\nfloat near = dot(axis, end_cyl) / dNV;\nvec3 end_point = ray_direction * near + ray_origin;\nif( dot(end_point - end_cyl, end_point-base) > radius2 )\ndiscard;\n#ifdef CAP\nnew_point = end_point;\n_normal = axis;\n#else\nnew_point = ray_target + ( (-a1 - sqrt(d)) / a2 ) * ray_direction;\ndNV = dot(-axis, ray_direction);\nnear = dot(-axis, (base)) / dNV;\nnew_point2 = ray_direction * near + ray_origin;\nif (dot(new_point2 - base, new_point2-base) < radius2)\ndiscard;\ninterior = true;\n#endif\n}\ngl_FragDepthEXT = calcDepth( new_point );\n#ifdef NEAR_CLIP\nif( calcClip( new_point ) > 0.0 ){\ndist = (-a1 - sqrt(d)) / a2;\nnew_point = ray_target + dist * ray_direction;\nif( calcClip( new_point ) > 0.0 )\ndiscard;\ninterior = true;\ngl_FragDepthEXT = calcDepth( new_point );\nif( gl_FragDepthEXT >= 0.0 ){\ngl_FragDepthEXT = max( 0.0, calcDepth( vec3( - ( nearClip - 0.5 ) ) ) + ( 0.0000001 / vRadius ) );\n}\n}else if( gl_FragDepthEXT <= 0.0 ){\ndist = (-a1 - sqrt(d)) / a2;\nnew_point = ray_target + dist * ray_direction;\ninterior = true;\ngl_FragDepthEXT = calcDepth( new_point );\nif( gl_FragDepthEXT >= 0.0 ){\ngl_FragDepthEXT = 0.0 + ( 0.0000001 / vRadius );\n}\n}\n#else\nif( gl_FragDepthEXT <= 0.0 ){\ndist = (-a1 - sqrt(d)) / a2;\nnew_point = ray_target + dist * ray_direction;\ninterior = true;\ngl_FragDepthEXT = calcDepth( new_point );\nif( gl_FragDepthEXT >= 0.0 ){\ngl_FragDepthEXT = 0.0 + ( 0.0000001 / vRadius );\n}\n}\n#endif\nif (gl_FragDepthEXT < 0.0)\ndiscard;\nif (gl_FragDepthEXT > 1.0)\ndiscard;\n#ifdef PICKING\ngl_FragColor = vec4( vPickingColor, objectId );\n#else\nvec3 vViewPosition = -new_point;\nvec3 vNormal = _normal;\nvec3 vColor;\nif( distSq3( new_point, end_cyl ) < distSq3( new_point, base ) ){\nif( b < 0.0 ){\nvColor = vColor1;\n}else{\nvColor = vColor2;\n}\n}else{\nif( b > 0.0 ){\nvColor = vColor1;\n}else{\nvColor = vColor2;\n}\n}\nvec4 diffuseColor = vec4( diffuse, opacity );\nReflectedLight reflectedLight = ReflectedLight( vec3( 0.0 ), vec3( 0.0 ), vec3( 0.0 ), vec3( 0.0 ) );\nvec3 totalEmissiveLight = emissive;\n#include color_fragment\n#include roughnessmap_fragment\n#include metalnessmap_fragment\nvec3 normal = normalize( vNormal );\nif( interior ){\nnormal = vec3( 0.0, 0.0, 0.4 );\n}\n#include lights_physical_fragment\n#include lights_template\nvec3 outgoingLight = reflectedLight.directDiffuse + reflectedLight.indirectDiffuse + reflectedLight.directSpecular + reflectedLight.indirectSpecular + totalEmissiveLight;\ngl_FragColor = vec4( outgoingLight, diffuseColor.a );\n#include premultiplied_alpha_fragment\n#include tonemapping_fragment\n#include encodings_fragment\n#include fog_fragment\n#endif\n}");var iy=new Float32Array([-1,1,-1,-1,-1,-1,1,1,-1,1,1,1,1,-1,-1,1,-1,1]),ry=new Uint16Array([0,1,2,1,4,2,2,4,3,4,5,3]),ny=function(t){function e(e,i){t.call(this,e,i);var r=i||{};this.openEnded=dn(r.openEnded,!1),this.addUniforms({modelViewMatrixInverse:{value:new v},ortho:{value:0}}),this.addAttributes({position1:{type:"v3",value:null},position2:{type:"v3",value:null},color2:{type:"c",value:null},radius:{type:"f",value:null}}),this.setAttributes(e),this.makeMapping()}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={parameters:{},isImpostor:{},vertexShader:{},fragmentShader:{}};return i.parameters.get=function(){return Object.assign.call(this,{openEnded:{updateShader:!0}},t.prototype.parameters)},e.prototype.getDefines=function(e){var i=t.prototype.getDefines.call(this,e);return this.openEnded||(i.CAP=1),i},i.isImpostor.get=function(){return!0},i.vertexShader.get=function(){return"CylinderImpostor.vert"},i.fragmentShader.get=function(){return"CylinderImpostor.frag"},Object.defineProperties(e.prototype,i),e}(function(t){function e(){t.apply(this,arguments)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={mapping:{},mappingIndices:{},mappingIndicesSize:{},mappingType:{},mappingSize:{},mappingItemSize:{}};return i.mapping.get=function(){return iy},i.mappingIndices.get=function(){return ry},i.mappingIndicesSize.get=function(){return 12},i.mappingType.get=function(){return"v3"},i.mappingSize.get=function(){return 6},i.mappingItemSize.get=function(){return 3},Object.defineProperties(e.prototype,i),e}(zv)),oy=function(t,e){return!sf||e&&e.disableImpostor?new ey(t,e):new ny(t,e)},ay=new g,sy=new g,cy=new g,uy=new g(0,1,0),hy=function(t){function e(e,i){var r=i||{},n=dn(r.radialSegments,60),o=dn(r.openEnded,!1),a=(new v).makeRotationX(-Math.PI/2),s=new gi(1,1,n,1,o);s.applyMatrix(a);var c=e.position1.length,u=e.radius.length,h=new Float32Array(c);t.call(this,{position:h,color:e.color,picking:e.picking},r,s),this._position=h,this._from=new Float32Array(c),this._to=new Float32Array(c),this._radius=new Float32Array(u),this.setAttributes(e,!0)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={updateNormals:{}};return e.prototype.applyPositionTransform=function(t,e,i){sy.fromArray(this._from,i),cy.fromArray(this._to,i),t.lookAt(sy,cy,uy);var r=this._radius[e];ay.set(r,r,sy.distanceTo(cy)),t.scale(ay)},e.prototype.setAttributes=function(e,i){var r={};e.position1&&e.position2&&(Mo(e.position1,e.position2,this._position),this._from.set(e.position1),this._to.set(e.position2),r.position=this._position),e.color&&(r.color=e.color),e.radius&&this._radius.set(e.radius),t.prototype.setAttributes.call(this,r,i)},i.updateNormals.get=function(){return!0},Object.defineProperties(e.prototype,i),e}(kv),ly=function(t,e){return new hy(t,e)},py=function(t){this.geometryList=t,this.boundingBox=null};py.prototype.computeBoundingBox=function(){var t=this;this.boundingBox?this.boundingBox.empty():this.boundingBox=new st,this.geometryList.forEach(function(e){e.boundingBox||e.computeBoundingBox(),t.boundingBox.union(e.boundingBox)})};var dy=function(t,e){var i=t||{},r=e||{};this.aspectRatio=dn(r.aspectRatio,1.5),this.wireframe=dn(r.wireframe,!1),this.splitPosition=new Float32Array(i.position1.length),this.cylinderRadius=new Float32Array(i.radius.length);var n=this.makeAttributes(i),o={radialSegments:dn(r.radialSegments,50),openEnded:dn(r.openEnded,!1),disableImpostor:dn(r.disableImpostor,!1)};this.cylinderBuffer=new oy(n.cylinder,o),this.coneBuffer=new ly(n.cone,o),this.geometry=new py([this.cylinderBuffer.geometry,this.coneBuffer.geometry]),this.group=new Re,this.wireframeGroup=new Re,this.pickingGroup=new Re,this.matrix=dn(r.matrix,new v),this.picking=i.picking},fy={matrix:{},pickable:{}};fy.matrix.set=function(t){Lv.prototype.setMatrix.call(this,t)},fy.matrix.get=function(){return this.group.matrix.clone()},fy.pickable.get=function(){return!!this.picking},dy.prototype.makeAttributes=function(t){var e,i,r=this.splitPosition,n=this.cylinderRadius,o=this.aspectRatio,a={},s={};if(t.radius){for(e=0,i=n.length;e<i;++e)n[e]=t.radius[e]/o;a.radius=n,s.radius=t.radius}if(t.position1&&t.position2){var c=new g,u=new g,h=new g,l=new g;for(e=0,i=r.length;e<i;e+=3){c.fromArray(t.position1,e),u.fromArray(t.position2,e),h.subVectors(c,u);var p=h.length(),d=n[e/3]*o*2,f=Math.min(p,d);h.setLength(f),l.copy(u).add(h),l.toArray(r,e)}a.position1=t.position1,a.position2=r,s.position1=r,s.position2=t.position2}return t.color&&(a.color=t.color,a.color2=t.color,s.color=t.color),{cylinder:a,cone:s}},dy.prototype.getMesh=function(t){return(new Re).add(this.cylinderBuffer.getMesh(t),this.coneBuffer.getMesh(t))},dy.prototype.getWireframeMesh=function(){return(new Re).add(this.cylinderBuffer.getWireframeMesh(),this.coneBuffer.getWireframeMesh())},dy.prototype.getPickingMesh=function(){return(new Re).add(this.cylinderBuffer.getPickingMesh(),this.coneBuffer.getPickingMesh())},dy.prototype.setAttributes=function(t){var e=this.makeAttributes(t);this.cylinderBuffer.setAttributes(e.cylinder),this.coneBuffer.setAttributes(e.cone)},dy.prototype.setParameters=function(t){(t=Object.assign({},t))&&void 0!==t.matrix&&(this.matrix=t.matrix),delete t.matrix,t&&void 0!==t.wireframe&&(this.wireframe=t.wireframe,this.setVisibility(this.visible)),this.cylinderBuffer.setParameters(t),this.coneBuffer.setParameters(t)},dy.prototype.setVisibility=function(){Lv.prototype.setVisibility.apply(this,arguments)},dy.prototype.dispose=function(){this.cylinderBuffer.dispose(),this.coneBuffer.dispose()},Object.defineProperties(dy.prototype,fy),mf.add("shader/SDFFont.vert","uniform float nearClip;\nuniform float clipRadius;\nuniform vec3 clipCenter;\nuniform float xOffset;\nuniform float yOffset;\nuniform float zOffset;\nuniform bool ortho;\n#if defined( NEAR_CLIP ) || defined( RADIUS_CLIP ) || ( !defined( PICKING ) && !defined( NOLIGHT ) )\nvarying vec3 vViewPosition;\n#endif\nvarying vec2 texCoord;\n#if defined( RADIUS_CLIP )\nvarying vec3 vClipCenter;\n#endif\n#if defined( PICKING )\n#include unpack_color\nattribute float primitiveId;\nvarying vec3 vPickingColor;\n#else\n#include color_pars_vertex\n#endif\nattribute vec2 mapping;\nattribute vec2 inputTexCoord;\nattribute float inputSize;\n#include matrix_scale\n#include common\nvoid main(void){\n#if defined( PICKING )\nvPickingColor = unpackColor( primitiveId );\n#else\n#include color_vertex\n#endif\ntexCoord = inputTexCoord;\nfloat scale = matrixScale( modelViewMatrix );\nfloat _zOffset = zOffset * scale;\nif( texCoord.x == 10.0 ){\n_zOffset -= 0.001;\n}\nvec3 pos = position;\nif( ortho ){\npos += normalize( cameraPosition ) * _zOffset;\n}\nvec4 cameraPos = modelViewMatrix * vec4( pos, 1.0 );\nvec4 cameraCornerPos = vec4( cameraPos.xyz, 1.0 );\ncameraCornerPos.xy += mapping * inputSize * 0.01 * scale;\ncameraCornerPos.x += xOffset * scale;\ncameraCornerPos.y += yOffset * scale;\nif( !ortho ){\ncameraCornerPos.xyz += normalize( -cameraCornerPos.xyz ) * _zOffset;\n}\ngl_Position = projectionMatrix * cameraCornerPos;\n#if defined( NEAR_CLIP ) || defined( RADIUS_CLIP ) || ( !defined( PICKING ) && !defined( NOLIGHT ) )\nvViewPosition = -cameraCornerPos.xyz;\n#endif\n#if defined( RADIUS_CLIP )\nvClipCenter = -( modelViewMatrix * vec4( clipCenter, 1.0 ) ).xyz;\n#endif\n#include nearclip_vertex\n#include radiusclip_vertex\n}"),mf.add("shader/SDFFont.frag","uniform sampler2D fontTexture;\nuniform float opacity;\nuniform bool showBorder;\nuniform vec3 borderColor;\nuniform float borderWidth;\nuniform vec3 backgroundColor;\nuniform float backgroundOpacity;\nuniform float nearClip;\nuniform float clipRadius;\nvarying vec3 vViewPosition;\nvarying vec2 texCoord;\n#if defined( RADIUS_CLIP )\nvarying vec3 vClipCenter;\n#endif\n#if defined( PICKING )\nuniform float objectId;\nvarying vec3 vPickingColor;\nconst vec3 vColor = vec3( 0.0 );\n#else\n#include common\n#include color_pars_fragment\n#include fog_pars_fragment\n#endif\n#ifdef SDF\nconst float smoothness = 16.0;\n#else\nconst float smoothness = 256.0;\n#endif\nconst float gamma = 2.2;\nvoid main(){\n#include nearclip_fragment\n#include radiusclip_fragment\nif( texCoord.x > 1.0 ){\ngl_FragColor = vec4( backgroundColor, backgroundOpacity );\n}else{\nfloat sdf = texture2D( fontTexture, texCoord ).a;\nif( showBorder ) sdf += borderWidth;\nfloat w = clamp(\nsmoothness * ( abs( dFdx( texCoord.x ) ) + abs( dFdy( texCoord.y ) ) ),\n0.0,\n0.5\n);\nfloat a = smoothstep( 0.5 - w, 0.5 + w, sdf );\na = pow( a, 1.0 / gamma );\nif( a < 0.2 ) discard;\na *= opacity;\nvec3 outgoingLight = vColor;\nif( showBorder && sdf < ( 0.5 + borderWidth ) ){\noutgoingLight = borderColor;\n}\ngl_FragColor = vec4( outgoingLight, a );\n}\n#if defined( PICKING )\ngl_FragColor = vec4( vPickingColor, objectId );\n#else\n#include premultiplied_alpha_fragment\n#include tonemapping_fragment\n#include encodings_fragment\n#include fog_fragment\n#endif\n}");var my={},gy=function(t){var e=Object.assign({},t);if(this.font=dn(e.font,["sans-serif"]),this.size=dn(e.size,36),this.style=dn(e.style,"normal"),this.variant=dn(e.variant,"normal"),this.weight=dn(e.weight,"normal"),this.outline=dn(e.outline,0),this.width=dn(e.width,2048),this.height=dn(e.height,2048),this.gamma=1,"undefined"!=typeof navigator){var i=navigator.userAgent;i.match(/Chrome/)&&i.match(/OS X/)&&(this.gamma=.5)}this.mapped={},this.scratchW=0,this.scratchH=0,this.currentX=0,this.currentY=0,this.build(),this.populate(),this.texture=new De(this.canvas2),this.texture.flipY=!1,this.texture.needsUpdate=!0};gy.prototype.build=function(){var t=this.size+2*this.outline+Math.round(this.size/4),e=this.width/4,i=document.createElement("canvas");i.width=e,i.height=t;var r=i.getContext("2d");r.font=this.style+" "+this.variant+" "+this.weight+" "+this.size+"px "+this.font,r.fillStyle="#FF0000",r.textAlign="left",r.textBaseline="bottom",r.lineJoin="round";for(var n=[],o=3*this.outline,a=0;a<o;++a){var s=("00"+Math.max(0,8*-a+128-8*!a).toString(16)).slice(-2);n.push("#"+s+s+s)}var c=new Uint8Array(e*t*2);this.canvas=i,this.context=r,this.lineHeight=t,this.maxWidth=e,this.colors=n,this.scratch=c,this.data=new Uint8Array(this.width*this.height*4),this.canvas2=document.createElement("canvas"),this.canvas2.width=this.width,this.canvas2.height=this.height,this.context2=this.canvas2.getContext("2d")},gy.prototype.map=function(t){return void 0===this.mapped[t]&&(this.draw(t),this.currentX+this.scratchW>this.width&&(this.currentX=0,this.currentY+=this.scratchH),this.currentY+this.scratchH>this.height&&console.warn("canvas to small"),this.mapped[t]={x:this.currentX,y:this.currentY,w:this.scratchW,h:this.scratchH},this.context2.drawImage(this.canvas,0,0,this.scratchW,this.scratchH,this.currentX,this.currentY,this.scratchW,this.scratchH),this.currentX+=this.scratchW),this.mapped[t]},gy.prototype.get=function(t){return this.mapped[t]||this.placeholder},gy.prototype.draw=function(t){var e=this.lineHeight,i=this.outline,r=this.context,n=this.scratch,o=this.maxWidth,a=this.colors,s=i,c=e-this.outline,u=r.measureText(t),h=Math.min(o,Math.ceil(u.width+2*s+1));r.clearRect(0,0,h,e);var l,p,d,f,m;if(0===this.outline)for(r.fillText(t,s,c),d=3,l=0,p=(m=(f=r.getImageData(0,0,h,e)).data).length/4;l<p;++l)n[l]=m[d],d+=4;else{for(r.globalCompositeOperation="source-over",l=i+1;l>0;--l)d=l>1?2*l-2:l,r.strokeStyle=a[d-1],r.lineWidth=d,r.strokeText(t,s,c);r.globalCompositeOperation="multiply",r.fillStyle="#FF00FF",r.fillText(t,s,c),m=(f=r.getImageData(0,0,h,e)).data,d=0;var g=this.gamma;for(l=0,p=m.length/4;l<p;++l){var v=m[d],y=v?m[d+1]/v:1;.5===g&&(y=Math.sqrt(y));var b=256-v,x=b+(v-b)*(y=Math.min(1,Math.max(0,y)));n[l]=Math.max(0,Math.min(255,x+2)),m[d+3]=n[l],d+=4}}r.putImageData(f,0,0),this.scratchW=h,this.scratchH=e},gy.prototype.populate=function(){var t=this;this.placeholder=this.map(String.fromCharCode(65533));for(var e=0;e<127;++e)t.map(String.fromCharCode(e));for(var i=128;i<255;++i)t.map(String.fromCharCode(i));for(var r=880;r<1023;++r)t.map(String.fromCharCode(r));for(var n=1024;n<1279;++n)t.map(String.fromCharCode(n));this.map(String.fromCharCode(8491))};var vy=function(t){function e(e,i){var r=e||{},n=i||{};n.forceTransparent=!0;for(var o=r.position.length/3,a=0,s=0;s<o;++s)a+=r.text[s].length;var c=a;n.showBackground&&(c+=o),t.call(this,{position:new Float32Array(3*c),color:new Float32Array(3*c),picking:new Qm},n),this.fontFamily=dn(n.fontFamily,"sans-serif"),this.fontStyle=dn(n.fontStyle,"normal"),this.fontWeight=dn(n.fontWeight,"bold"),this.fontSize=dn(n.fontSize,48),this.sdf=dn(n.sdf,"Chrome"===nf),this.xOffset=dn(n.xOffset,0),this.yOffset=dn(n.yOffset,0),this.zOffset=dn(n.zOffset,.5),this.attachment=dn(n.attachment,"bottom-left"),this.showBorder=dn(n.showBorder,!1),this.borderColor=dn(n.borderColor,"lightgrey"),this.borderWidth=dn(n.borderWidth,.15),this.showBackground=dn(n.showBackground,!1),this.backgroundColor=dn(n.backgroundColor,"lightgrey"),this.backgroundMargin=dn(n.backgroundMargin,.5),this.backgroundOpacity=dn(n.backgroundOpacity,1),this.text=r.text,this.positionCount=o,this.addUniforms({fontTexture:{value:null},xOffset:{value:this.xOffset},yOffset:{value:this.yOffset},zOffset:{value:this.zOffset},ortho:{value:!1},showBorder:{value:this.showBorder},borderColor:{value:new tt(this.borderColor)},borderWidth:{value:this.borderWidth},backgroundColor:{value:new tt(this.backgroundColor)},backgroundOpacity:{value:this.backgroundOpacity}}),this.addAttributes({inputTexCoord:{type:"v2",value:null},inputSize:{type:"f",value:null}}),this.setAttributes(e),this.makeTexture(),this.makeMapping()}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={parameters:{},wireframe:{},isText:{},vertexShader:{},fragmentShader:{}};return i.parameters.get=function(){return Object.assign.call(this,{fontFamily:{uniform:!0},fontStyle:{uniform:!0},fontWeight:{uniform:!0},fontSize:{uniform:!0},sdf:{updateShader:!0,uniform:!0},xOffset:{uniform:!0},yOffset:{uniform:!0},zOffset:{uniform:!0},showBorder:{uniform:!0},borderColor:{uniform:!0},borderWidth:{uniform:!0},backgroundColor:{uniform:!0},backgroundOpacity:{uniform:!0}},t.prototype.parameters,{flatShaded:void 0})},e.prototype.makeMaterial=function(){t.prototype.makeMaterial.call(this);var e=this.texture,i=this.material;i.extensions.derivatives=!0,i.lights=!1,i.uniforms.fontTexture.value=e,i.needsUpdate=!0;var r=this.wireframeMaterial;r.extensions.derivatives=!0,r.lights=!1,r.uniforms.fontTexture.value=e,r.needsUpdate=!0;var n=this.pickingMaterial;n.extensions.derivatives=!0,n.lights=!1,n.uniforms.fontTexture.value=e,n.needsUpdate=!0},e.prototype.setAttributes=function(t){var e,i,r,n,o,a,s=this,c=this.text,u=this.geometry.attributes;t.position&&(e=t.position,n=u.position.array,u.position.needsUpdate=!0),t.size&&(i=t.size,o=u.inputSize.array,u.inputSize.needsUpdate=!0),t.color&&(r=t.color,a=u.color.array,u.color.needsUpdate=!0);for(var h,l,p,d,f=this.positionCount,m=0,g=0;g<f;++g)for(l=3*g,d=c[g].length,s.showBackground&&(d+=1),p=0;p<d;++p,++m)for(var v=0;v<4;v++)h=4*m*3+3*v,e&&(n[h]=e[l],n[h+1]=e[l+1],n[h+2]=e[l+2]),i&&(o[4*m+v]=i[g]),r&&(a[h]=r[l],a[h+1]=r[l+1],a[h+2]=r[l+2])},e.prototype.makeTexture=function(){this.textAtlas=xs({font:[this.fontFamily],style:this.fontStyle,weight:this.fontWeight,size:this.fontSize,outline:this.sdf?5:0}),this.texture=this.textAtlas.texture},e.prototype.makeMapping=function(){for(var t,e,i,r,n,o,a,s,c=this,u=this.textAtlas,h=this.text,l=this.attachment,p=u.lineHeight*this.backgroundMargin*.1-10,d=this.geometry.attributes.inputTexCoord.array,f=this.geometry.attributes.mapping.array,m=this.positionCount,g=0,v=0;v<m;++v){for(r=0,o=(i=h[v]).length,n=0;n<o;++n)r+=(t=u.get(i[n])).w-2*u.outline;for(s=l.startsWith("top")?u.lineHeight/1.25:l.startsWith("middle")?u.lineHeight/2.5:0,a=l.endsWith("right")?r:l.endsWith("center")?r/2:0,a+=u.outline,s+=u.outline,c.showBackground&&(f[(e=2*g*4)+0]=-u.lineHeight/6-a-p,f[e+1]=u.lineHeight-s+p,f[e+2]=-u.lineHeight/6-a-p,f[e+3]=0-s-p,f[e+4]=r+u.lineHeight/6-a+2*u.outline+p,f[e+5]=u.lineHeight-s+p,f[e+6]=r+u.lineHeight/6-a+2*u.outline+p,f[e+7]=0-s-p,d[e+0]=10,d[e+2]=10,d[e+4]=10,d[e+6]=10,g+=1),r=0,n=0;n<o;++n,++g){t=u.get(i[n]),f[(e=2*g*4)+0]=r-a,f[e+1]=t.h-s,f[e+2]=r-a,f[e+3]=0-s,f[e+4]=r+t.w-a,f[e+5]=t.h-s,f[e+6]=r+t.w-a,f[e+7]=0-s;var y=u.width,b=u.height,x=[t.x/y,t.y/b,t.x/y,(t.y+t.h)/b,(t.x+t.w)/y,t.y/b,(t.x+t.w)/y,(t.y+t.h)/b];d.set(x,e),r+=t.w-2*u.outline}}this.geometry.attributes.inputTexCoord.needsUpdate=!0,this.geometry.attributes.mapping.needsUpdate=!0},e.prototype.getDefines=function(e){var i=t.prototype.getDefines.call(this,e);return this.sdf&&(i.SDF=1),i},e.prototype.setUniforms=function(e){!e||void 0===e.fontFamily&&void 0===e.fontStyle&&void 0===e.fontWeight&&void 0===e.fontSize&&void 0===e.sdf||(this.makeTexture(),this.makeMapping(),this.texture.needsUpdate=!0,e.fontTexture=this.texture),t.prototype.setUniforms.call(this,e)},i.wireframe.set=function(t){},i.wireframe.get=function(){return!1},i.isText.get=function(){return!0},i.vertexShader.get=function(){return"SDFFont.vert"},i.fragmentShader.get=function(){return"SDFFont.frag"},Object.defineProperties(e.prototype,i),e}(Gv),yy=new g,by=new st,xy=function(t,e){this.name=dn(t,"shape");var i=e||{};this.aspectRatio=dn(i.aspectRatio,1.5),this.sphereDetail=dn(i.sphereDetail,2),this.radialSegments=dn(i.radialSegments,50),this.disableImpostor=dn(i.disableImpostor,!1),this.openEnded=dn(i.openEnded,!1),this.labelParams=dn(i.labelParams,{}),this.boundingBox=new st,this.bufferList=[],this.meshCount=0,this.spherePosition=[],this.sphereColor=[],this.sphereRadius=[],this.sphereName=[],this.ellipsoidPosition=[],this.ellipsoidColor=[],this.ellipsoidRadius=[],this.ellipsoidMajorAxis=[],this.ellipsoidMinorAxis=[],this.ellipsoidName=[],this.cylinderPosition1=[],this.cylinderPosition2=[],this.cylinderColor=[],this.cylinderRadius=[],this.cylinderName=[],this.conePosition1=[],this.conePosition2=[],this.coneColor=[],this.coneRadius=[],this.coneName=[],this.arrowPosition1=[],this.arrowPosition2=[],this.arrowColor=[],this.arrowRadius=[],this.arrowName=[],this.labelPosition=[],this.labelColor=[],this.labelSize=[],this.labelText=[]},_y={center:{},type:{}};xy.prototype.addBuffer=function(t){this.bufferList.push(t);var e=t.geometry;return e.boundingBox||e.computeBoundingBox(),this.boundingBox.union(e.boundingBox),this},xy.prototype.addMesh=function(t,e,i,r,n){t=kn(t),e=kn(e),Array.isArray(i)&&(i=Cn(i,t.length)),r&&(r=kn(r));var o={position:t,color:e,index:i,normal:r},a=new Jm(this,Object.assign({serial:this.meshCount,name:n},o)),s=new Ov(Object.assign({picking:a},o));return this.bufferList.push(s),by.setFromArray(t),this.boundingBox.union(by),this.meshCount+=1,this},xy.prototype.addSphere=function(t,e,i,r){return _s(t,this.spherePosition),_s(e,this.sphereColor),this.sphereRadius.push(i),this.sphereName.push(r),this.boundingBox.expandByPoint(yy.fromArray(t)),this},xy.prototype.addEllipsoid=function(t,e,i,r,n,o){return _s(t,this.ellipsoidPosition),_s(e,this.ellipsoidColor),this.ellipsoidRadius.push(i),_s(r,this.ellipsoidMajorAxis),_s(n,this.ellipsoidMinorAxis),this.ellipsoidName.push(o),this.boundingBox.expandByPoint(yy.fromArray(t)),this},xy.prototype.addCylinder=function(t,e,i,r,n){return _s(t,this.cylinderPosition1),_s(e,this.cylinderPosition2),_s(i,this.cylinderColor),this.cylinderRadius.push(r),this.cylinderName.push(n),this.boundingBox.expandByPoint(yy.fromArray(t)),this.boundingBox.expandByPoint(yy.fromArray(e)),this},xy.prototype.addCone=function(t,e,i,r,n){return _s(t,this.conePosition1),_s(e,this.conePosition2),_s(i,this.coneColor),this.coneRadius.push(r),this.coneName.push(n),this.boundingBox.expandByPoint(yy.fromArray(t)),this.boundingBox.expandByPoint(yy.fromArray(e)),this},xy.prototype.addArrow=function(t,e,i,r,n){return _s(t,this.arrowPosition1),_s(e,this.arrowPosition2),_s(i,this.arrowColor),this.arrowRadius.push(r),this.arrowName.push(n),this.boundingBox.expandByPoint(yy.fromArray(t)),this.boundingBox.expandByPoint(yy.fromArray(e)),this},xy.prototype.addLabel=function(t,e,i,r){return _s(t,this.labelPosition),_s(e,this.labelColor),this.labelSize.push(i),this.labelText.push(r),this.boundingBox.expandByPoint(yy.fromArray(t)),this},xy.prototype.getBufferList=function(){var t=[];if(this.spherePosition.length){var e=new $v({position:new Float32Array(this.spherePosition),color:new Float32Array(this.sphereColor),radius:new Float32Array(this.sphereRadius),picking:new tg(this)},{sphereDetail:this.sphereDetail,disableImpostor:this.disableImpostor});t.push(e)}if(this.ellipsoidPosition.length){var i=new Zv({position:new Float32Array(this.ellipsoidPosition),color:new Float32Array(this.ellipsoidColor),radius:new Float32Array(this.ellipsoidRadius),majorAxis:new Float32Array(this.ellipsoidMajorAxis),minorAxis:new Float32Array(this.ellipsoidMinorAxis),picking:new Km(this)},{sphereDetail:this.sphereDetail,disableImpostor:this.disableImpostor});t.push(i)}if(this.cylinderPosition1.length){var r=new oy({position1:new Float32Array(this.cylinderPosition1),position2:new Float32Array(this.cylinderPosition2),color:new Float32Array(this.cylinderColor),color2:new Float32Array(this.cylinderColor),radius:new Float32Array(this.cylinderRadius),picking:new Gm(this)},{radialSegments:this.radialSegments,disableImpostor:this.disableImpostor,openEnded:this.openEnded});t.push(r)}if(this.conePosition1.length){var n=new ly({position1:new Float32Array(this.conePosition1),position2:new Float32Array(this.conePosition2),color:new Float32Array(this.coneColor),radius:new Float32Array(this.coneRadius),picking:new qm(this)},{radialSegments:this.radialSegments,disableImpostor:this.disableImpostor,openEnded:this.openEnded});t.push(n)}if(this.arrowPosition1.length){var o=new dy({position1:new Float32Array(this.arrowPosition1),position2:new Float32Array(this.arrowPosition2),color:new Float32Array(this.arrowColor),radius:new Float32Array(this.arrowRadius),picking:new Vm(this)},{aspectRatio:this.aspectRatio,radialSegments:this.radialSegments,disableImpostor:this.disableImpostor,openEnded:this.openEnded});t.push(o)}if(this.labelPosition.length){var a=new vy({position:new Float32Array(this.labelPosition),color:new Float32Array(this.labelColor),size:new Float32Array(this.labelSize),text:this.labelText},this.labelParams);t.push(a)}return this.bufferList.concat(t)},xy.prototype.dispose=function(){this.bufferList.forEach(function(t){t.dispose()}),this.bufferList.length=0,this.spherePosition.length=0,this.sphereColor.length=0,this.sphereRadius.length=0,this.sphereName.length=0,this.ellipsoidPosition.length=0,this.ellipsoidColor.length=0,this.ellipsoidRadius.length=0,this.ellipsoidMajorAxis.length=0,this.ellipsoidMinorAxis.length=0,this.ellipsoidName.length=0,this.cylinderPosition1.length=0,this.cylinderPosition2.length=0,this.cylinderColor.length=0,this.cylinderRadius.length=0,this.cylinderName.length=0,this.conePosition1.length=0,this.conePosition2.length=0,this.coneColor.length=0,this.coneRadius.length=0,this.coneName.length=0,this.arrowPosition1.length=0,this.arrowPosition2.length=0,this.arrowColor.length=0,this.arrowRadius.length=0,this.arrowName.length=0,this.labelPosition.length=0,this.labelColor.length=0,this.labelSize.length=0,this.labelText.length=0},_y.center.get=function(){return this._center||(this._center=this.boundingBox.getCenter()),this._center},_y.type.get=function(){return"Shape"},Object.defineProperties(xy.prototype,_y);var wy=function(t,e,i){this.type="",this.parameters={lazy:{type:"boolean"},clipNear:{type:"range",step:1,max:100,min:0,buffer:!0},clipRadius:{type:"number",precision:1,max:1e3,min:0,buffer:!0},clipCenter:{type:"vector3",precision:1,buffer:!0},flatShaded:{type:"boolean",buffer:!0},opacity:{type:"range",step:.01,max:1,min:0,buffer:!0},depthWrite:{type:"boolean",buffer:!0},side:{type:"select",buffer:!0,options:{front:"front",back:"back",double:"double"}},wireframe:{type:"boolean",buffer:!0},linewidth:{type:"integer",max:50,min:1,buffer:!0},colorScheme:{type:"select",update:"color",options:{}},colorScale:{type:"select",update:"color",options:lf.getScales()},colorReverse:{type:"boolean",update:"color"},colorValue:{type:"color",update:"color"},colorDomain:{type:"hidden",update:"color"},colorMode:{type:"select",update:"color",options:lf.getModes()},roughness:{type:"range",step:.01,max:1,min:0,buffer:!0},metalness:{type:"range",step:.01,max:1,min:0,buffer:!0},diffuse:{type:"color",buffer:!0},matrix:{type:"hidden",buffer:!0}},this.viewer=e,this.tasks=new Cf,this.queue=new ms(this.make.bind(this)),this.bufferList=[],this.parameters.colorScheme&&(this.parameters.colorScheme.options=lf.getSchemes())};wy.prototype.init=function(t){var e=t||{};this.clipNear=dn(e.clipNear,0),this.clipRadius=dn(e.clipRadius,0),this.clipCenter=dn(e.clipCenter,new g),this.flatShaded=dn(e.flatShaded,!1),this.side=dn(e.side,"double"),this.opacity=dn(e.opacity,1),this.depthWrite=dn(e.depthWrite,!0),this.wireframe=dn(e.wireframe,!1),this.linewidth=dn(e.linewidth,2),this.setColor(e.color,e),this.colorScheme=dn(e.colorScheme,"uniform"),this.colorScale=dn(e.colorScale,""),this.colorReverse=dn(e.colorReverse,!1),this.colorValue=dn(e.colorValue,9474192),this.colorDomain=dn(e.colorDomain,void 0),this.colorMode=dn(e.colorMode,"hcl"),this.visible=dn(e.visible,!0),this.quality=dn(e.quality,void 0),this.roughness=dn(e.roughness,.4),this.metalness=dn(e.metalness,0),this.diffuse=dn(e.diffuse,16777215),this.lazy=dn(e.lazy,!1),this.lazyProps={build:!1,bufferParams:{},what:{}},this.matrix=dn(e.matrix,new v);var i=this.parameters;!0===i.sphereDetail&&(i.sphereDetail={type:"integer",max:3,min:0,rebuild:"impostor"}),!0===i.radialSegments&&(i.radialSegments={type:"integer",max:25,min:5,rebuild:"impostor"}),!0===i.openEnded&&(i.openEnded={type:"boolean",rebuild:"impostor",buffer:!0}),!0===i.disableImpostor&&(i.disableImpostor={type:"boolean",rebuild:!0}),"low"===e.quality?(i.sphereDetail&&(this.sphereDetail=0),i.radialSegments&&(this.radialSegments=5)):"medium"===e.quality?(i.sphereDetail&&(this.sphereDetail=1),i.radialSegments&&(this.radialSegments=10)):"high"===e.quality?(i.sphereDetail&&(this.sphereDetail=2),i.radialSegments&&(this.radialSegments=20)):(i.sphereDetail&&(this.sphereDetail=dn(e.sphereDetail,1)),i.radialSegments&&(this.radialSegments=dn(e.radialSegments,10))),i.openEnded&&(this.openEnded=dn(e.openEnded,!0)),i.disableImpostor&&(this.disableImpostor=dn(e.disableImpostor,!1))},wy.prototype.getColorParams=function(t){return Object.assign({scheme:this.colorScheme,scale:this.colorScale,reverse:this.colorReverse,value:this.colorValue,domain:this.colorDomain,mode:this.colorMode},t)},wy.prototype.getBufferParams=function(t){return Object.assign({clipNear:this.clipNear,clipRadius:this.clipRadius,clipCenter:this.clipCenter,flatShaded:this.flatShaded,opacity:this.opacity,depthWrite:this.depthWrite,side:this.side,wireframe:this.wireframe,linewidth:this.linewidth,roughness:this.roughness,metalness:this.metalness,diffuse:this.diffuse,matrix:this.matrix},t)},wy.prototype.setColor=function(t,e){return Object.keys(lf.getSchemes()).includes(t)?e?e.colorScheme=t:this.setParameters({colorScheme:t}):void 0!==t&&(t=new tt(t).getHex(),e?(e.colorScheme="uniform",e.colorValue=t):this.setParameters({colorScheme:"uniform",colorValue:t})),this},wy.prototype.create=function(){},wy.prototype.update=function(){this.build()},wy.prototype.build=function(t){return this.lazy&&!this.visible?void(this.lazyProps.build=!0):this.prepare?(this.queue.length()>0?(this.tasks.change(1-this.queue.length()),this.queue.kill()):this.tasks.increment(),void this.queue.push(t||!1)):(this.tasks.increment(),void this.make())},wy.prototype.make=function(e,i){t.Debug&&cf.time("Representation.make "+this.type);var r=function(){e?(this.update(e),this.viewer.requestRender(),this.tasks.decrement(),i&&i()):(this.clear(),this.create(),this.manualAttach||this.disposed||(t.Debug&&cf.time("Representation.attach "+this.type),this.attach(function(){t.Debug&&cf.timeEnd("Representation.attach "+this.type),this.tasks.decrement(),i&&i()}.bind(this)))),t.Debug&&cf.timeEnd("Representation.make "+this.type)}.bind(this);this.prepare?this.prepare(r):r()},wy.prototype.attach=function(t){this.setVisibility(this.visible),t()},wy.prototype.setVisibility=function(t,e){if(this.visible=t,this.visible){var i=this.lazyProps,r=i.bufferParams,n=i.what;if(i.build)return i.build=!1,void this.build();(Object.keys(r).length||Object.keys(n).length)&&(i.bufferParams={},i.what={},this.updateParameters(r,n))}return this.bufferList.forEach(function(e){e.setVisibility(t)}),e||this.viewer.requestRender(),this},wy.prototype.setParameters=function(t,e,i){var r=this,n=t||{},o=this.parameters;e=e||{},i=i||!1;var a={};for(var s in n)void 0!==n[s]&&void 0!==o[s]&&(o[s].int&&(n[s]=parseInt(n[s])),o[s].float&&(n[s]=parseFloat(n[s])),(n[s]!==r[s]||n[s].equals&&!n[s].equals(r[s]))&&(r[s].set?r[s].set(n[s]):r[s]=n[s],o[s].buffer&&(!0===o[s].buffer?a[s]=n[s]:a[o[s].buffer]=n[s]),o[s].update&&(e[o[s].update]=!0),!o[s].rebuild||"impostor"===o[s].rebuild&&sf&&!r.disableImpostor||(i=!0)));return i?this.build():this.updateParameters(a,e),this},wy.prototype.updateParameters=function(t,e){if(this.lazy&&!this.visible)return Object.assign(this.lazyProps.bufferParams,t),void Object.assign(this.lazyProps.what,e);this.bufferList.forEach(function(e){e.setParameters(t)}),Object.keys(e).length&&this.update(e),this.viewer.requestRender()},wy.prototype.getParameters=function(){var t=this,e={lazy:this.lazy,visible:this.visible,quality:this.quality};return Object.keys(this.parameters).forEach(function(i){null!==t.parameters[i]&&(e[i]=t[i])}),e},wy.prototype.clear=function(){var t=this;this.bufferList.forEach(function(e){t.viewer.remove(e),e.dispose()}),this.bufferList.length=0,this.viewer.requestRender()},wy.prototype.dispose=function(){this.disposed=!0,this.queue.kill(),this.tasks.dispose(),this.clear()};var Sy=function(t){function e(e,i,r){Array.isArray(e)||(e=[e]),t.call(this,e,i,r),this.type="buffer",this.parameters=Object.assign({},this.parameters,{colorScheme:null,colorScale:null,colorValue:null,colorDomain:null,colorMode:null}),this.buffer=e,this.init(r)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){t.prototype.init.call(this,e),this.build()},e.prototype.create=function(){this.bufferList.push.apply(this.bufferList,this.buffer)},e.prototype.attach=function(t){var e=this;this.bufferList.forEach(function(t){e.viewer.add(t),t.setParameters(e.getBufferParams())}),this.setVisibility(this.visible),t()},e}(wy),Ay=function(t){function e(){t.apply(this,arguments)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={isSurface:{}};return i.isSurface.get=function(){return!0},Object.defineProperties(e.prototype,i),e}(Ov),My=function(t){this.size=t.size,this.side=t.side,this.wireframe=t.wireframe,this.visible=t.visible,this.geometry=t.geometry,this.picking=t.picking,this.background=t.background,this.group=new Re,this.wireframeGroup=new Re,this.pickingGroup=new Re,this.matrix=t.matrix,this.frontMeshes=[],this.backMeshes=[];var e=t,i=new t.constructor;e.makeMaterial(),i.makeMaterial(),i.picking=t.picking,i.geometry=t.geometry,i.wireframeGeometry=t.wireframeGeometry,i.setParameters(t.getParameters()),i.updateShader(),e.setParameters({side:"front"}),i.setParameters({side:"back",opacity:i.opacity}),this.buffer=t,this.frontBuffer=e,this.backBuffer=i},Py={matrix:{},pickable:{}};Py.matrix.set=function(t){Lv.prototype.setMatrix.call(this,t)},Py.matrix.get=function(){return this.group.matrix.clone()},Py.pickable.get=function(){return!!this.picking},My.prototype.getMesh=function(t){var e,i;return t?(i=this.backBuffer.getPickingMesh(),e=this.frontBuffer.getPickingMesh()):(i=this.backBuffer.getMesh(),e=this.frontBuffer.getMesh()),this.frontMeshes.push(e),this.backMeshes.push(i),this.setParameters({side:this.side}),(new Re).add(i,e)},My.prototype.getWireframeMesh=function(){return this.buffer.getWireframeMesh()},My.prototype.getPickingMesh=function(){return this.getMesh(!0)},My.prototype.setAttributes=function(t){this.buffer.setAttributes(t)},My.prototype.setParameters=function(t){"front"===(t=Object.assign({},t)).side?(this.frontMeshes.forEach(ws),this.backMeshes.forEach(Ss)):"back"===t.side?(this.frontMeshes.forEach(Ss),this.backMeshes.forEach(ws)):"double"===t.side&&(this.frontMeshes.forEach(ws),this.backMeshes.forEach(ws)),void 0!==t.matrix&&(this.matrix=t.matrix),delete t.matrix,void 0!==t.side&&(this.side=t.side),delete t.side,this.frontBuffer.setParameters(t),void 0!==t.wireframe&&(this.wireframe=t.wireframe,this.setVisibility(this.visible)),delete t.wireframe,this.backBuffer.setParameters(t)},My.prototype.dispose=function(){this.frontBuffer.dispose(),this.backBuffer.dispose()},Object.defineProperties(My.prototype,Py),My.prototype.setVisibility=Lv.prototype.setVisibility,mf.add("shader/Line.vert","uniform float nearClip;\nuniform vec3 clipCenter;\nvarying vec3 vViewPosition;\n#if defined( RADIUS_CLIP )\nvarying vec3 vClipCenter;\n#endif\n#include color_pars_vertex\nvoid main(){\n#include color_vertex\n#include begin_vertex\n#include project_vertex\nvViewPosition = -mvPosition.xyz;\n#if defined( RADIUS_CLIP )\nvClipCenter = -( modelViewMatrix * vec4( clipCenter, 1.0 ) ).xyz;\n#endif\n#include nearclip_vertex\n}"),mf.add("shader/Line.frag","uniform float opacity;\nuniform float nearClip;\nuniform float clipRadius;\nvarying vec3 vViewPosition;\n#if defined( RADIUS_CLIP )\nvarying vec3 vClipCenter;\n#endif\n#include common\n#include color_pars_fragment\n#include fog_pars_fragment\nvoid main(){\n#include nearclip_fragment\n#include radiusclip_fragment\ngl_FragColor = vec4( vColor, opacity );\n#include premultiplied_alpha_fragment\n#include tonemapping_fragment\n#include encodings_fragment\n#include fog_fragment\n}");var Ty=function(t){function e(){t.apply(this,arguments)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={isLine:{},vertexShader:{},fragmentShader:{}};return i.isLine.get=function(){return!0},i.vertexShader.get=function(){return"Line.vert"},i.fragmentShader.get=function(){return"Line.frag"},Object.defineProperties(e.prototype,i),e}(Lv),Ey=function(t){function e(e,i,r){t.call(this,e,i,r),this.type="surface",this.parameters=Object.assign({isolevelType:{type:"select",options:{value:"value",sigma:"sigma"}},isolevel:{type:"number",precision:2,max:1e3,min:-1e3},negateIsolevel:{type:"boolean"},smooth:{type:"integer",precision:1,max:10,min:0},background:{type:"boolean",rebuild:!0},opaqueBack:{type:"boolean",buffer:!0},boxSize:{type:"integer",precision:1,max:100,min:0},colorVolume:{type:"hidden"},contour:{type:"boolean",rebuild:!0},useWorker:{type:"boolean",rebuild:!0},wrap:{type:"boolean",rebuild:!0}},this.parameters),e instanceof Vg?(this.surface=void 0,this.volume=e):(this.surface=e,this.volume=void 0),this.boxCenter=new g,this.__boxCenter=new g,this.box=new st,this.__box=new st,this._position=new g,this.setBox=function(){this._position.copy(i.translationGroup.position).negate(),this._position.equals(this.boxCenter)||this.setParameters({boxCenter:this._position})},this.viewer.signals.ticked.add(this.setBox,this),this.init(r)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=e||{};i.colorScheme=dn(i.colorScheme,"uniform"),i.colorValue=dn(i.colorValue,14540253),this.isolevelType=dn(i.isolevelType,"sigma"),this.isolevel=dn(i.isolevel,2),this.negateIsolevel=dn(i.negateIsolevel,!1),this.smooth=dn(i.smooth,0),this.background=dn(i.background,!1),this.opaqueBack=dn(i.opaqueBack,!0),this.boxSize=dn(i.boxSize,0),this.colorVolume=dn(i.colorVolume,void 0),this.contour=dn(i.contour,!1),this.useWorker=dn(i.useWorker,!0),this.wrap=dn(i.wrap,!1),t.prototype.init.call(this,i),this.build()},e.prototype.attach=function(t){var e=this;this.bufferList.forEach(function(t){e.viewer.add(t)}),this.setVisibility(this.visible),t()},e.prototype.prepare=function(t){var e=this;if(this.volume){var i;if(i="sigma"===this.isolevelType?this.volume.getValueForSigma(this.isolevel):this.isolevel,this.negateIsolevel&&(i*=-1),!this.surface||this.__isolevel!==i||this.__smooth!==this.smooth||this.__contour!==this.contour||this.__wrap!==this.wrap||this.__boxSize!==this.boxSize||this.boxSize>0&&!this.__boxCenter.equals(this.boxCenter)){this.__isolevel=i,this.__smooth=this.smooth,this.__contour=this.contour,this.__wrap=this.wrap,this.__boxSize=this.boxSize,this.__boxCenter.copy(this.boxCenter),this.__box.copy(this.box);var r=function(i){e.surface=i,t()};this.useWorker?this.volume.getSurfaceWorker(i,this.smooth,this.boxCenter,this.boxSize,this.contour,this.wrap,r):r(this.volume.getSurface(i,this.smooth,this.boxCenter,this.boxSize,this.contour,this.wrap))}else t()}else t()},e.prototype.create=function(){var t,e={position:this.surface.getPosition(),color:this.surface.getColor(this.getColorParams()),index:this.surface.getIndex()};if(this.contour)t=new Ty(e,this.getBufferParams({wireframe:!1}));else{e.normal=this.surface.getNormal(),e.picking=this.surface.getPicking();var i=new Ay(e,this.getBufferParams({background:this.background,opaqueBack:this.opaqueBack,dullInterior:!1}));t=new My(i)}this.bufferList.push(t)},e.prototype.update=function(t){if(0!==this.bufferList.length){var e={};(t=t||{}).position&&(e.position=this.surface.getPosition()),t.color&&(e.color=this.surface.getColor(this.getColorParams())),t.index&&(e.index=this.surface.getIndex()),t.normal&&(e.normal=this.surface.getNormal()),this.bufferList.forEach(function(t){t.setAttributes(e)})}},e.prototype.setParameters=function(e,i,r){return e&&void 0!==e.isolevelType&&this.volume&&("value"===this.isolevelType&&"sigma"===e.isolevelType?this.isolevel=this.volume.getSigmaForValue(this.isolevel):"sigma"===this.isolevelType&&"value"===e.isolevelType&&(this.isolevel=this.volume.getValueForSigma(this.isolevel)),this.isolevelType=e.isolevelType),e&&e.boxCenter&&(this.boxCenter.copy(e.boxCenter),delete e.boxCenter),e&&e.wireframe&&(e.contour||void 0===e.contour&&this.contour)&&(e.wireframe=!1),t.prototype.setParameters.call(this,e,i,r),this.volume&&this.volume.getBox(this.boxCenter,this.boxSize,this.box),e&&void 0!==e.colorVolume&&(i.color=!0),this.surface&&(void 0!==e.isolevel||void 0!==e.negateIsolevel||void 0!==e.smooth||void 0!==e.wrap||void 0!==e.boxSize||this.boxSize>0&&!this.__box.equals(this.box))&&this.build({position:!0,color:!0,index:!0,normal:!this.contour}),this},e.prototype.getColorParams=function(){var e=t.prototype.getColorParams.call(this);return e.volume=this.colorVolume,e},e.prototype.dispose=function(){this.viewer.signals.ticked.remove(this.setBox,this),t.prototype.dispose.call(this)},e}(wy);mf.add("shader/Point.vert","uniform float nearClip;\nuniform float clipRadius;\nuniform vec3 clipCenter;\nuniform float size;\nuniform float canvasHeight;\nuniform float pixelRatio;\nvarying vec3 vViewPosition;\n#if defined( RADIUS_CLIP )\nvarying vec3 vClipCenter;\n#endif\n#if defined( PICKING )\n#include unpack_color\nattribute float primitiveId;\nvarying vec3 vPickingColor;\n#else\n#include color_pars_vertex\n#endif\n#include common\nvoid main(){\n#if defined( PICKING )\nvPickingColor = unpackColor( primitiveId );\n#else\n#include color_vertex\n#endif\n#include begin_vertex\n#include project_vertex\n#ifdef USE_SIZEATTENUATION\ngl_PointSize = size * pixelRatio * ( ( canvasHeight / 2.0 ) / -mvPosition.z );\n#else\ngl_PointSize = size * pixelRatio;\n#endif\nvViewPosition = -mvPosition.xyz;\n#if defined( RADIUS_CLIP )\nvClipCenter = -( modelViewMatrix * vec4( clipCenter, 1.0 ) ).xyz;\n#endif\n#include nearclip_vertex\n#include radiusclip_vertex\n}"),mf.add("shader/Point.frag","uniform vec3 diffuse;\nuniform float opacity;\nuniform float nearClip;\nuniform float clipRadius;\nvarying vec3 vViewPosition;\n#if defined( RADIUS_CLIP )\nvarying vec3 vClipCenter;\n#endif\n#ifdef USE_MAP\nuniform sampler2D map;\n#endif\n#if defined( PICKING )\nuniform float objectId;\nvarying vec3 vPickingColor;\n#else\n#include common\n#include color_pars_fragment\n#include fog_pars_fragment\n#endif\nvoid main(){\n#include nearclip_fragment\n#include radiusclip_fragment\n#if defined( PICKING )\n#ifdef USE_MAP\nif( texture2D( map, vec2( gl_PointCoord.x, 1.0 - gl_PointCoord.y ) ).a < 0.5 )\ndiscard;\n#endif\ngl_FragColor = vec4( vPickingColor, objectId );\n#else\nvec3 outgoingLight = vec3( 0.0 );\nvec4 diffuseColor = vec4( diffuse, 1.0 );\n#ifdef USE_MAP\ndiffuseColor *= texture2D( map, vec2( gl_PointCoord.x, 1.0 - gl_PointCoord.y ) );\n#endif\n#include color_fragment\n#include alphatest_fragment\noutgoingLight = diffuseColor.rgb;\ngl_FragColor = vec4( outgoingLight, diffuseColor.a * opacity );\n#include premultiplied_alpha_fragment\n#include tonemapping_fragment\n#include encodings_fragment\n#include fog_fragment\n#endif\n}");var Cy=function(t){function e(e,i){var r=e||{},n=i||{};r.primitiveId||(r.primitiveId=Co(r.position.length/3)),t.call(this,r,n),this.pointSize=dn(n.pointSize,1),this.sizeAttenuation=dn(n.sizeAttenuation,!0),this.sortParticles=dn(n.sortParticles,!1),this.alphaTest=dn(n.alphaTest,.5),this.useTexture=dn(n.useTexture,!1),this.forceTransparent=dn(n.forceTransparent,!1),this.edgeBleach=dn(n.edgeBleach,0),this.addUniforms({size:{value:this.pointSize},canvasHeight:{value:1},pixelRatio:{value:1},map:{value:null}})}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={parameters:{},isPoint:{},vertexShader:{},fragmentShader:{}};return i.parameters.get=function(){return Object.assign.call(this,{pointSize:{uniform:"size"},sizeAttenuation:{updateShader:!0},sortParticles:{},alphaTest:{updateShader:!0},useTexture:{updateShader:!0},forceTransparent:{},edgeBleach:{uniform:!0}},t.prototype.parameters)},e.prototype.makeMaterial=function(){t.prototype.makeMaterial.call(this),this.makeTexture();var e=this.material,i=this.wireframeMaterial,r=this.pickingMaterial;e.uniforms.map.value=this.tex,e.needsUpdate=!0,i.uniforms.map.value=this.tex,i.needsUpdate=!0,r.uniforms.map.value=this.tex,r.needsUpdate=!0},e.prototype.makeTexture=function(){this.tex&&this.tex.dispose(),this.tex=Ms({delta:this.edgeBleach})},e.prototype.getDefines=function(e){var i=t.prototype.getDefines.call(this,e);return this.sizeAttenuation&&(i.USE_SIZEATTENUATION=1),this.useTexture&&(i.USE_MAP=1),this.alphaTest>0&&this.alphaTest<=1&&(i.ALPHATEST=this.alphaTest.toPrecision(2)),i},e.prototype.setUniforms=function(e){e&&void 0!==e.edgeBleach&&(this.makeTexture(),e.map=this.tex),t.prototype.setUniforms.call(this,e)},e.prototype.dispose=function(){t.prototype.dispose.call(this),this.tex&&this.tex.dispose()},i.isPoint.get=function(){return!0},i.vertexShader.get=function(){return"Point.vert"},i.fragmentShader.get=function(){return"Point.frag"},Object.defineProperties(e.prototype,i),e}(Lv),Iy=function(t){function e(e,i,r){t.call(this,e,i,r),this.type="dot",this.parameters=Object.assign({thresholdType:{type:"select",rebuild:!0,options:{value:"value",sigma:"sigma"}},thresholdMin:{type:"number",precision:3,max:1/0,min:-1/0,rebuild:!0},thresholdMax:{type:"number",precision:3,max:1/0,min:-1/0,rebuild:!0},thresholdOut:{type:"boolean",rebuild:!0},dotType:{type:"select",rebuild:!0,options:{"":"",sphere:"sphere",point:"point"}},radiusType:{type:"select",options:{"":"",value:"value","abs-value":"abs-value","value-min":"value-min",deviation:"deviation",size:"size"}},radius:{type:"number",precision:3,max:10,min:.001,property:"size"},scale:{type:"number",precision:3,max:10,min:.001},sphereDetail:!0,disableImpostor:!0,pointSize:{type:"number",precision:1,max:100,min:0,buffer:!0},sizeAttenuation:{type:"boolean",buffer:!0},sortParticles:{type:"boolean",rebuild:!0},useTexture:{type:"boolean",buffer:!0},alphaTest:{type:"range",step:.001,max:1,min:0,buffer:!0},forceTransparent:{type:"boolean",buffer:!0},edgeBleach:{type:"range",step:.001,max:1,min:0,buffer:!0}},this.parameters,{colorScheme:{type:"select",update:"color",options:{"":"",value:"value",uniform:"uniform",random:"random"}}}),e instanceof Vg?(this.surface=void 0,this.volume=new Hg(e)):(this.surface=e,this.volume=void 0),this.init(r)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=e||{};i.colorScheme=dn(i.colorScheme,"uniform"),i.colorValue=dn(i.colorValue,14540253),this.thresholdType=dn(i.thresholdType,"sigma"),this.thresholdMin=dn(i.thresholdMin,2),this.thresholdMax=dn(i.thresholdMax,1/0),this.thresholdOut=dn(i.thresholdOut,!1),this.dotType=dn(i.dotType,"point"),this.radius=dn(i.radius,.1),this.scale=dn(i.scale,1),this.pointSize=dn(i.pointSize,1),this.sizeAttenuation=dn(i.sizeAttenuation,!0),this.sortParticles=dn(i.sortParticles,!1),this.useTexture=dn(i.useTexture,!1),this.alphaTest=dn(i.alphaTest,.5),this.forceTransparent=dn(i.forceTransparent,!1),this.edgeBleach=dn(i.edgeBleach,0),t.prototype.init.call(this,i),this.build()},e.prototype.attach=function(t){var e=this;this.bufferList.forEach(function(t){e.viewer.add(t)}),this.setVisibility(this.visible),t()},e.prototype.create=function(){var t={};if(this.volume){var e,i,r=this.volume;"sigma"===this.thresholdType?(e=r.getValueForSigma(this.thresholdMin),i=r.getValueForSigma(this.thresholdMax)):(e=this.thresholdMin,i=this.thresholdMax),r.setFilter(e,i,this.thresholdOut),t.position=r.getDataPosition(),t.color=r.getDataColor(this.getColorParams()),"sphere"===this.dotType&&(t.radius=r.getDataSize(this.radius,this.scale),t.picking=r.getDataPicking())}else{var n=this.surface;t.position=n.getPosition(),t.color=n.getColor(this.getColorParams()),"sphere"===this.dotType&&(t.radius=n.getSize(this.radius,this.scale),t.picking=n.getPicking())}"sphere"===this.dotType?this.dotBuffer=new $v(t,this.getBufferParams({sphereDetail:this.sphereDetail,disableImpostor:this.disableImpostor,dullInterior:!1})):this.dotBuffer=new Cy(t,this.getBufferParams({pointSize:this.pointSize,sizeAttenuation:this.sizeAttenuation,sortParticles:this.sortParticles,useTexture:this.useTexture,alphaTest:this.alphaTest,forceTransparent:this.forceTransparent,edgeBleach:this.edgeBleach})),this.bufferList.push(this.dotBuffer)},e.prototype.update=function(t){if(0!==this.bufferList.length){var e={};(t=t||{}).color&&(this.volume?e.color=this.volume.getDataColor(this.getColorParams()):e.color=this.surface.getColor(this.getColorParams())),"sphere"===this.dotType&&(t.radius||t.scale)&&(this.volume?e.radius=this.volume.getDataSize(this.radius,this.scale):e.radius=this.surface.getSize(this.radius,this.scale)),this.dotBuffer.setAttributes(e)}},e.prototype.setParameters=function(e,i,r){return i=i||{},e&&void 0!==e.thresholdType&&this.volume instanceof Vg&&("value"===this.thresholdType&&"sigma"===e.thresholdType?(this.thresholdMin=this.volume.getSigmaForValue(this.thresholdMin),this.thresholdMax=this.volume.getSigmaForValue(this.thresholdMax)):"sigma"===this.thresholdType&&"value"===e.thresholdType&&(this.thresholdMin=this.volume.getValueForSigma(this.thresholdMin),this.thresholdMax=this.volume.getValueForSigma(this.thresholdMax)),this.thresholdType=e.thresholdType),e&&void 0!==e.radiusType&&("radius"===e.radiusType?this.radius=.1:this.radius=e.radiusType,i.radius=!0,"sphere"!==this.dotType||sf&&!this.disableImpostor||(r=!0)),e&&void 0!==e.radius&&(i.radius=!0,"sphere"!==this.dotType||sf&&!this.disableImpostor||(r=!0)),e&&void 0!==e.scale&&(i.scale=!0,"sphere"!==this.dotType||sf&&!this.disableImpostor||(r=!0)),t.prototype.setParameters.call(this,e,i,r),this},e}(wy);mf.add("shader/Image.vert","uniform float clipRadius;\nuniform vec3 clipCenter;\nvarying vec2 vUv;\n#if defined( NEAR_CLIP ) || defined( RADIUS_CLIP ) || !defined( PICKING )\nvarying vec3 vViewPosition;\n#endif\n#if defined( RADIUS_CLIP )\nvarying vec3 vClipCenter;\n#endif\nvoid main() {\n#include begin_vertex\n#include project_vertex\nvUv = uv;\n#if defined( NEAR_CLIP ) || defined( RADIUS_CLIP ) || !defined( PICKING )\nvViewPosition = -mvPosition.xyz;\n#endif\n#if defined( RADIUS_CLIP )\nvClipCenter = -( modelViewMatrix * vec4( clipCenter, 1.0 ) ).xyz;\n#endif\n}"),mf.add("shader/Image.frag","uniform sampler2D map;\nuniform float opacity;\nuniform vec2 mapSize;\nuniform float nearClip;\nuniform float clipRadius;\nvarying vec2 vUv;\n#if defined( NEAR_CLIP ) || defined( RADIUS_CLIP ) || !defined( PICKING )\nvarying vec3 vViewPosition;\n#endif\n#if defined( RADIUS_CLIP )\nvarying vec3 vClipCenter;\n#endif\n#if defined( PICKING )\nuniform sampler2D pickingMap;\nuniform float objectId;\n#else\n#include fog_pars_fragment\n#endif\n#if defined( CUBIC_INTERPOLATION )\n#if defined( CATMULROM_FILTER ) || defined( MITCHELL_FILTER )\n#if defined( CATMULROM_FILTER )\nconst float B = 0.0;\nconst float C = 0.5;\n#elif defined( MITCHELL_FILTER )\nconst float B = 0.333;\nconst float C = 0.333;\n#endif\nfloat filter( float x ){\nfloat f = x;\nif( f < 0.0 ){\nf = -f;\n}\nif( f < 1.0 ){\nreturn ( ( 12.0 - 9.0 * B - 6.0 * C ) * ( f * f * f ) +\n( -18.0 + 12.0 * B + 6.0 *C ) * ( f * f ) +\n( 6.0 - 2.0 * B ) ) / 6.0;\n}else if( f >= 1.0 && f < 2.0 ){\nreturn ( ( -B - 6.0 * C ) * ( f * f * f )\n+ ( 6.0 * B + 30.0 * C ) * ( f *f ) +\n( - ( 12.0 * B ) - 48.0 * C ) * f +\n8.0 * B + 24.0 * C ) / 6.0;\n}else{\nreturn 0.0;\n}\n}\n#elif defined( BSPLINE_FILTER )\nfloat filter( float x ){\nfloat f = x;\nif( f < 0.0 ){\nf = -f;\n}\nif( f >= 0.0 && f <= 1.0 ){\nreturn ( 2.0 / 3.0 ) + ( 0.5 ) * ( f * f * f ) - ( f * f );\n}else if( f > 1.0 && f <= 2.0 ){\nreturn 1.0 / 6.0 * pow( ( 2.0 - f ), 3.0 );\n}\nreturn 1.0;\n}\n#else\nfloat filter( float x ){\nreturn 1.0;\n}\n#endif\nvec4 biCubic( sampler2D tex, vec2 texCoord ){\nvec2 texelSize = 1.0 / mapSize;\ntexCoord -= texelSize / 2.0;\nvec4 nSum = vec4( 0.0 );\nfloat nDenom = 0.0;\nvec2 cell = fract( texCoord * mapSize );\nfor( float m = -1.0; m <= 2.0; ++m ){\nfor( float n = -1.0; n <= 2.0; ++n ){\nvec4 vecData = texture2D(\ntex, texCoord + texelSize * vec2( m, n )\n);\nfloat c = filter( m - cell.x ) * filter( -n + cell.y );\nnSum += vecData * c;\nnDenom += c;\n}\n}\nreturn nSum / nDenom;\n}\n#endif\nvoid main(){\n#include nearclip_fragment\n#include radiusclip_fragment\n#if defined( CUBIC_INTERPOLATION )\ngl_FragColor = biCubic( map, vUv );\n#else\ngl_FragColor = texture2D( map, vUv );\n#endif\n#if defined( PICKING )\nif( gl_FragColor.a < 0.7 )\ndiscard;\ngl_FragColor = vec4( texture2D( pickingMap, vUv ).xyz, objectId );\n#else\nif( gl_FragColor.a < 0.01 )\ndiscard;\ngl_FragColor.a *= opacity;\n#include fog_fragment\n#endif\n}");var Ly=new Uint16Array([0,1,2,1,3,2]),Ry=new Float32Array([0,1,0,0,1,1,1,0]),Oy=function(t){function e(e,i){var r=e||{},n=i||{};t.call(this,{position:r.position,index:Ly,picking:r.picking},n),this.forceTransparent=!0,this.filter=dn(n.filter,"nearest");var o=new y(r.imageData,r.width,r.height);o.flipY=!0,this.tex=o;for(var a=r.imageData.length,s=new Uint8Array(a),c=0;c<a;c+=4){var u=c/4;s[c]=u>>16&255,s[c+1]=u>>8&255,s[c+2]=255&u}var h=new y(s,r.width,r.height);h.flipY=!0,h.minFilter=Ph,h.magFilter=Ph,this.pickingTex=h,this.addUniforms({map:{value:o},pickingMap:{value:h},mapSize:{value:new l(r.width,r.height)}}),this.geometry.addAttribute("uv",new _t(Ry,2))}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={parameters:{},vertexShader:{},fragmentShader:{}};return i.parameters.get=function(){return Object.assign.call(this,{filter:{updateShader:!0,uniform:!0}},t.prototype.parameters)},e.prototype.getDefines=function(e){var i=t.prototype.getDefines.call(this,e);return this.filter.startsWith("cubic")&&(i.CUBIC_INTERPOLATION=1,this.filter.endsWith("bspline")?i.BSPLINE_FILTER=1:this.filter.endsWith("catmulrom")?i.CATMULROM_FILTER=1:this.filter.endsWith("mitchell")&&(i.MITCHELL_FILTER=1)),i},e.prototype.updateTexture=function(){var t=this.tex;this.filter.startsWith("cubic")?(t.minFilter=Ph,t.magFilter=Ph):"linear"===this.filter?(t.minFilter=Ch,t.magFilter=Ch):(t.minFilter=Ph,t.magFilter=Ph),t.needsUpdate=!0,this.pickingTex.needsUpdate=!0},e.prototype.makeMaterial=function(){t.prototype.makeMaterial.call(this),this.updateTexture();var e=this.material;e.uniforms.map.value=this.tex,e.blending=Ou,e.needsUpdate=!0;var i=this.wireframeMaterial;i.uniforms.map.value=this.tex,i.blending=Ou,i.needsUpdate=!0;var r=this.pickingMaterial;r.uniforms.map.value=this.tex,r.uniforms.pickingMap.value=this.pickingTex,r.blending=Ou,r.needsUpdate=!0},e.prototype.setUniforms=function(e){e&&void 0!==e.filter&&(this.updateTexture(),e.map=this.tex),t.prototype.setUniforms.call(this,e)},i.vertexShader.get=function(){return"Image.vert"},i.fragmentShader.get=function(){return"Image.frag"},Object.defineProperties(e.prototype,i),e}(Lv),Dy=function(t,e){var i=e||{};this.dimension=dn(i.dimension,"x"),this.positionType=dn(i.positionType,"percent"),this.position=dn(i.position,30),this.thresholdType=dn(i.thresholdType,"sigma"),this.thresholdMin=dn(i.thresholdMin,-1/0),this.thresholdMax=dn(i.thresholdMax,1/0),this.normalize=dn(i.normalize,!1),this.volume=t};Dy.prototype.getPositionFromCoordinate=function(t){var e,i=this.dimension,r=this.volume,n=r.matrix,o=(new g).setFromMatrixPosition(n)[i],a=(new g).setFromMatrixScale(n)[i];return e="x"===i?r.nx:"y"===i?r.ny:r.nz,Math.round(((t-o)/(e/100)+1)/a)},Dy.prototype.getData=function(t){function e(t){return Math.round(t/100*(o-1))}function i(t,e,i,r){return 3*(i*a.ny*a.nx+e*a.nx+t)+r}function r(t,e,i,r){m.set(t,e,i).applyMatrix4(c).toArray(f,r)}var n=this;t=t||{};var o,a=this.volume,s=a.data,c=a.matrix;o="coordinate"===this.positionType?this.getPositionFromCoordinate(this.position):this.position;var u,h,l,p,d,f=new Float32Array(12),m=new g,v=0,y=0,b=0,x=a.nx,_=a.ny,w=a.nz;"x"===this.dimension?(l=e(a.nx),p=a.ny-1,d=a.nz-1,u=a.nz,h=a.ny,x=(v=l)+1,r(l,0,0,0),r(l,p,0,3),r(l,0,d,6),r(l,p,d,9)):"y"===this.dimension?(l=a.nx-1,p=e(a.ny),d=a.nz-1,u=a.nz,h=a.nx,_=(y=p)+1,r(0,p,0,0),r(l,p,0,3),r(0,p,d,6),r(l,p,d,9)):"z"===this.dimension&&(l=a.nx-1,p=a.ny-1,d=e(a.nz),u=a.nx,h=a.ny,w=(b=d)+1,r(0,0,d,0),r(0,p,d,3),r(l,0,d,6),r(l,p,d,9));var S,A,M=0,P=0,T=new Uint8Array(u*h*4),E=new Float32Array(u*h);"sigma"===this.thresholdType?(S=a.getValueForSigma(this.thresholdMin),A=a.getValueForSigma(this.thresholdMax)):(S=this.thresholdMin,A=this.thresholdMax);var C=Object.assign({},t.colorParams,{volume:a});this.normalize&&(C.domain=[0,1]);var I,L,R,O=lf.getScheme(C),D=new Float32Array(3),N=O.getScale();if(this.normalize){I=1/0,L=-1/0;for(var k=y;k<_;++k)for(var B=v;B<x;++B)for(var F=b;F<w;++F){var z=s[i(B,k,F,0)/3];z<I&&(I=z),z>L&&(L=z)}R=L-I}for(var U=y;U<_;++U)for(var j=v;j<x;++j)for(var G=b;G<w;++G){var V=i(j,U,G,0)/3,$=s[V];n.normalize&&($=($-I)/R),O.colorToArray(N($),D),T[M]=Math.round(255*D[0]),T[M+1]=Math.round(255*D[1]),T[M+2]=Math.round(255*D[2]),T[M+3]=$>S&&$<A?255:0,E[P]=V,++P,M+=4}var H=new ng(E,a);return{position:f,imageData:T,width:u,height:h,picking:H}};var Ny=function(t){function e(e,i,r){t.call(this,e,i,r),this.type="slice",this.parameters=Object.assign({filter:{type:"select",buffer:!0,options:{nearest:"nearest",linear:"linear","cubic-bspline":"cubic-bspline","cubic-catmulrom":"cubic-catmulrom","cubic-mitchell":"cubic-mitchell"}},positionType:{type:"select",rebuild:!0,options:{percent:"percent",coordinate:"coordinate"}},position:{type:"range",step:.1,max:100,min:1,rebuild:!0},dimension:{type:"select",rebuild:!0,options:{x:"x",y:"y",z:"z"}},thresholdType:{type:"select",rebuild:!0,options:{value:"value",sigma:"sigma"}},thresholdMin:{type:"number",precision:3,max:1/0,min:-1/0,rebuild:!0},thresholdMax:{type:"number",precision:3,max:1/0,min:-1/0,rebuild:!0},normalize:{type:"boolean",rebuild:!0}},this.parameters,{flatShaded:null,side:null,wireframe:null,linewidth:null,colorScheme:null,roughness:null,metalness:null,diffuse:null}),this.volume=e,this.init(r)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=this.volume,r=e||{};r.colorDomain=dn(r.colorDomain,[i.min,i.max]),r.colorScheme=dn(r.colorScheme,"value"),r.colorScale=dn(r.colorScale,"Spectral"),this.colorScheme="value",this.dimension=dn(r.dimension,"x"),this.filter=dn(r.filter,"cubic-bspline"),this.positionType=dn(r.positionType,"percent"),this.position=dn(r.position,30),this.thresholdType=dn(r.thresholdType,"sigma"),this.thresholdMin=dn(r.thresholdMin,-1/0),this.thresholdMax=dn(r.thresholdMax,1/0),this.normalize=dn(r.normalize,!1),t.prototype.init.call(this,r),this.build()},e.prototype.attach=function(t){var e=this;this.bufferList.forEach(function(t){e.viewer.add(t)}),this.setVisibility(this.visible),t()},e.prototype.create=function(){var t=new Dy(this.volume,{positionType:this.positionType,position:this.position,dimension:this.dimension,thresholdType:this.thresholdType,thresholdMin:this.thresholdMin,thresholdMax:this.thresholdMax,normalize:this.normalize}),e=new Oy(t.getData({colorParams:this.getColorParams()}),this.getBufferParams({filter:this.filter}));this.bufferList.push(e)},e}(wy),ky=function(t){function e(e,i,r){var n=r||{};if(t.call(this,e,i,n),this.type="structure",this.parameters=Object.assign({radiusType:{type:"select",options:ga.types},radius:{type:"number",precision:3,max:10,min:.001},scale:{type:"number",precision:3,max:10,min:.001},assembly:null,defaultAssembly:{type:"hidden"}},this.parameters),this.selection=new Kd(n.sele),this.dataList=[],this.structure=e,this.structureView=this.structure.getView(this.selection),e.biomolDict){var o={default:"default","":e.unitcell?"AU":"FULL"};Object.keys(e.biomolDict).forEach(function(t){o[t]=t}),this.parameters.assembly={type:"select",options:o,rebuild:!0}}else this.parameters.assembly=null}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={defaultScale:{}};return i.defaultScale.get=function(){return{vdw:1,covalent:1,bfactor:.01,sstruc:1}},e.prototype.init=function(e){var i=e||{};i.colorScheme=dn(i.colorScheme,"element"),this.radius=dn(i.radius,"vdw"),this.scale=dn(i.scale,1),this.assembly=dn(i.assembly,"default"),this.defaultAssembly=dn(i.defaultAssembly,""),"auto"===i.quality&&(i.quality=this.getQuality()),t.prototype.init.call(this,i),this.selection.signals.stringChanged.add(function(){this.build()},this),this.build()},e.prototype.getAssembly=function(){var t="default"===this.assembly?this.defaultAssembly:this.assembly;return this.structure.biomolDict[t]},e.prototype.getQuality=function(){var t,e=this.structureView,i=this.getAssembly();return t=i?i.getAtomCount(e):e.atomCount,of&&(t*=4),e.atomStore.count/e.residueStore.count<2&&(t*=10),t<15e3?"high":t<8e4?"medium":"low"},e.prototype.create=function(){if(0!==this.structureView.atomCount){var t=this.getAssembly();if(t)t.partList.forEach(function(t,e){var i=t.getView(this.structureView);if(0!==i.atomCount){var r=this.createData(i,e);r&&(r.sview=i,r.instanceList=t.getInstanceList(),this.dataList.push(r))}},this);else{var e=this.createData(this.structureView,0);e&&(e.sview=this.structureView,this.dataList.push(e))}}},e.prototype.createData=function(){console.error("createData not implemented")},e.prototype.update=function(t){if(this.lazy&&!this.visible)return void Object.assign(this.lazyProps.what,t);this.dataList.forEach(function(e){e.bufferList.length>0&&this.updateData(t,e)},this)},e.prototype.updateData=function(){this.build()},e.prototype.getColorParams=function(){var e=t.prototype.getColorParams.call(this);return e.structure=this.structure,e},e.prototype.getAtomParams=function(t,e){return Object.assign({what:t,colorParams:this.getColorParams(),radiusParams:{radius:this.radius,scale:this.scale}},e)},e.prototype.getBondParams=function(t,e){return Object.assign({what:t,colorParams:this.getColorParams(),radiusParams:{radius:this.radius,scale:this.scale}},e)},e.prototype.setSelection=function(t,e){return this.selection.setString(t,e),this},e.prototype.setParameters=function(e,i,r){return i=i||{},e&&void 0!==e.radiusType&&("size"===e.radiusType?this.radius=1:this.radius=e.radiusType,delete e.radiusType,i.radius=!0,sf&&!this.disableImpostor||(r=!0)),e&&void 0!==e.radius&&(i.radius=!0,sf&&!this.disableImpostor||(r=!0)),e&&void 0!==e.scale&&(i.radius=!0,sf&&!this.disableImpostor||(r=!0)),e&&void 0!==e.defaultAssembly&&(r=!0),t.prototype.setParameters.call(this,e,i,r),this},e.prototype.getParameters=function(){return Object.assign(t.prototype.getParameters.call(this),{sele:this.selection?this.selection.string:void 0,defaultAssembly:this.defaultAssembly})},e.prototype.attach=function(t){var e=this.viewer,i=this.bufferList;this.dataList.forEach(function(t){t.bufferList.forEach(function(r){i.push(r),e.add(r,t.instanceList)})}),this.setVisibility(this.visible),t()},e.prototype.clear=function(){this.dataList.length=0,t.prototype.clear.call(this)},e.prototype.dispose=function(){this.structureView.dispose(),delete this.structure,delete this.structureView,t.prototype.dispose.call(this)},Object.defineProperties(e.prototype,i),e}(wy),By=function(t){function e(e,i){var r=4*(e.position1.length/3);t.call(this,{position:new Float32Array(3*r),color:new Float32Array(3*r)},i),this.setAttributes(e)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={isLine:{},vertexShader:{},fragmentShader:{}};return e.prototype.setAttributes=function(t){var e,i,r,n,o,a,s=this.geometry.attributes;t.position1&&t.position2&&(e=t.position1,i=t.position2,o=s.position.array,s.position.needsUpdate=!0),t.color&&t.color2&&(r=t.color,n=t.color2,a=s.color.array,s.color.needsUpdate=!0);for(var c,u,h,l,p,d,f,m,g,v,y,b=this.size,x=0;x<b;x++)u=3*x,c=4*x*3,e&&i&&(d=e[u],f=e[u+1],m=e[u+2],h=(d+(g=i[u]))/2,l=(f+(v=i[u+1]))/2,p=(m+(y=i[u+2]))/2,o[c]=d,o[c+1]=f,o[c+2]=m,o[c+3]=h,o[c+4]=l,o[c+5]=p,o[c+6]=h,o[c+7]=l,o[c+8]=p,o[c+9]=g,o[c+10]=v,o[c+11]=y),r&&n&&(a[c]=a[c+3]=r[u],a[c+1]=a[c+4]=r[u+1],a[c+2]=a[c+5]=r[u+2],a[c+6]=a[c+9]=n[u],a[c+7]=a[c+10]=n[u+1],a[c+8]=a[c+11]=n[u+2])},i.isLine.get=function(){return!0},i.vertexShader.get=function(){return"Line.vert"},i.fragmentShader.get=function(){return"Line.frag"},Object.defineProperties(e.prototype,i),e}(Lv),Fy=function(t){function e(e,i,r){t.call(this,e.structure,i,r),this.type="trajectory",this.parameters=Object.assign({drawLine:{type:"boolean",rebuild:!0},drawCylinder:{type:"boolean",rebuild:!0},drawPoint:{type:"boolean",rebuild:!0},drawSphere:{type:"boolean",rebuild:!0},linewidth:{type:"integer",max:20,min:1,rebuild:!0},pointSize:{type:"integer",max:20,min:1,rebuild:!0},sizeAttenuation:{type:"boolean",rebuild:!0},sort:{type:"boolean",rebuild:!0}},this.parameters),this.manualAttach=!0,this.trajectory=e,this.init(r)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=e||{};i.colorScheme=dn(i.colorScheme,"uniform"),i.colorValue=dn(i.colorValue,14540253),this.drawLine=dn(i.drawLine,!0),this.drawCylinder=dn(i.drawCylinder,!1),this.drawPoint=dn(i.drawPoint,!1),this.drawSphere=dn(i.drawSphere,!1),this.pointSize=dn(i.pointSize,1),this.sizeAttenuation=dn(i.sizeAttenuation,!1),this.sort=dn(i.sort,!0),t.prototype.init.call(this,i)},e.prototype.attach=function(t){var e=this;this.bufferList.forEach(function(t){e.viewer.add(t)}),this.setVisibility(this.visible),t()},e.prototype.prepare=function(t){t()},e.prototype.create=function(){if(0!==this.atomSet.atomCount){var t=this,e=this.atomSet.atoms[0].index;this.trajectory.getPath(e,function(e){var i=e.length/3,r=new tt(t.colorValue);if(t.drawSphere){var n=new $v({position:e,color:To(i,r.r,r.g,r.b),radius:Po(i,.2)},t.getBufferParams({sphereDetail:t.sphereDetail,dullInterior:!0,disableImpostor:t.disableImpostor}));t.bufferList.push(n)}if(t.drawCylinder){var o=new oy({position1:e.subarray(0,-3),position2:e.subarray(3),color:To(i-1,r.r,r.g,r.b),color2:To(i-1,r.r,r.g,r.b),radius:Po(i,.05)},t.getBufferParams({openEnded:!1,radialSegments:t.radialSegments,disableImpostor:t.disableImpostor,dullInterior:!0}));t.bufferList.push(o)}if(t.drawPoint){var a=new Cy({position:e,color:To(i,r.r,r.g,r.b)},t.getBufferParams({pointSize:t.pointSize,sizeAttenuation:t.sizeAttenuation,sort:t.sort}));t.bufferList.push(a)}if(t.drawLine){var s=new By({position1:e.subarray(0,-3),position2:e.subarray(3),color:To(i-1,r.r,r.g,r.b),color2:To(i-1,r.r,r.g,r.b)},t.getBufferParams());t.bufferList.push(s)}t.attach()})}},e}(ky),zy=0,Uy=new v,jy=new g,Gy=function(t,e){Object.defineProperty(this,"id",{value:zy++});var i=e||{};this.name=i.name,this.uuid=$n(),this.visible=void 0===i.visible||i.visible,this.signals={representationAdded:new io,representationRemoved:new io,visibilityChanged:new io,matrixChanged:new io,statusChanged:new io,nameChanged:new io,disposed:new io},this.stage=t,this.viewer=t.viewer,this.reprList=[],this.annotationList=[],this.matrix=new v,this.position=new g,this.quaternion=new m,this.scale=new g(1,1,1),this.transform=new v,this.controls=new Fm(this)},Vy={type:{}};Vy.type.get=function(){return"component"},Gy.prototype.setPosition=function(t){return Array.isArray(t)?this.position.fromArray(t):this.position.copy(t),this.updateMatrix(),this},Gy.prototype.setRotation=function(t){if(Array.isArray(t))if(3===t.length){var e=(new ft).fromArray(t);this.quaternion.setFromEuler(e)}else this.quaternion.fromArray(t);else t instanceof ft?this.quaternion.setFromEuler(t):this.quaternion.copy(t);return this.updateMatrix(),this},Gy.prototype.setScale=function(t){return this.scale.set(t,t,t),this.updateMatrix(),this},Gy.prototype.setTransform=function(t){return this.transform.copy(t),this.updateMatrix(),this},Gy.prototype.updateMatrix=function(){var t=this,e=this.getCenterUntransformed(jy);this.matrix.makeTranslation(-e.x,-e.y,-e.z),Uy.makeRotationFromQuaternion(this.quaternion),this.matrix.premultiply(Uy),Uy.makeScale(this.scale.x,this.scale.y,this.scale.z),this.matrix.premultiply(Uy);var i=this.position;Uy.makeTranslation(i.x+e.x,i.y+e.y,i.z+e.z),this.matrix.premultiply(Uy),this.matrix.premultiply(this.transform),this.reprList.forEach(function(e){e.setParameters({matrix:t.matrix})}),this.stage.viewer.updateBoundingBox(),this.signals.matrixChanged.dispatch(this.matrix)},Gy.prototype.addAnnotation=function(t,e,i){var r=new Dm(this,t,e,i);return this.annotationList.push(r),r},Gy.prototype.removeAnnotation=function(t){var e=this.annotationList.indexOf(t);-1!==e&&(this.annotationList.splice(e,1),t.dispose())},Gy.prototype.removeAllAnnotations=function(){this.annotationList.forEach(function(t){t.dispose()}),this.annotationList.length=0},Gy.prototype.addRepresentation=function(t,e,i){var r=i||{},n=this.stage.getParameters();r.matrix=this.matrix.clone(),r.quality=r.quality||n.quality,r.disableImpostor=dn(r.disableImpostor,!n.impostor),r.useWorker=dn(r.useWorker,n.workerDefault),r.visible=dn(r.visible,!0);var o=Object.assign({},r,{visible:this.visible&&r.visible}),a=Ts(t,e,this.viewer,o),s=this.__getRepresentationComponent(a,r);return this.reprList.push(s),this.signals.representationAdded.dispatch(s),s},Gy.prototype.addBufferRepresentation=function(t,e){return Gy.prototype.addRepresentation.call(this,"buffer",t,e)},Gy.prototype.hasRepresentation=function(t){return-1!==this.reprList.indexOf(t)},Gy.prototype.removeRepresentation=function(t){var e=this.reprList.indexOf(t);-1!==e&&(this.reprList.splice(e,1),t.dispose(),this.signals.representationRemoved.dispatch(t))},Gy.prototype.updateRepresentations=function(t){this.reprList.forEach(function(e){e.update(t)}),this.stage.viewer.requestRender()},Gy.prototype.removeAllRepresentations=function(){var t=this;this.reprList.forEach(function(e){e.dispose(),t.signals.representationRemoved.dispatch(e)}),this.reprList.length=0},Gy.prototype.dispose=function(){this.removeAllAnnotations(),this.removeAllRepresentations(),delete this.annotationList,delete this.reprList,this.signals.disposed.dispatch()},Gy.prototype.setVisibility=function(t){return this.visible=t,this.eachRepresentation(function(t){t.updateVisibility()}),this.annotationList.forEach(function(t){t.updateVisibility()}),this.signals.visibilityChanged.dispatch(t),this},Gy.prototype.setStatus=function(t){return this.status=t,this.signals.statusChanged.dispatch(t),this},Gy.prototype.setName=function(t){return this.name=t,this.signals.nameChanged.dispatch(t),this},Gy.prototype.getBox=function(){return(t=this).getBoxUntransformed.apply(t,arguments).clone().applyMatrix4(this.matrix);var t},Gy.prototype.getCenter=function(){return(t=this).getCenterUntransformed.apply(t,arguments).clone().applyMatrix4(this.matrix);var t},Gy.prototype.getZoom=function(){return this.stage.getZoomForBox((t=this).getBox.apply(t,arguments));var t},Gy.prototype.getBoxUntransformed=function(){},Gy.prototype.getCenterUntransformed=function(){return this.getBoxUntransformed().getCenter()},Gy.prototype.autoView=function(t){this.stage.animationControls.zoomMove(this.getCenter(),this.getZoom(),dn(t,0))},Gy.prototype.eachRepresentation=function(t){this.reprList.forEach(t)},Object.defineProperties(Gy.prototype,Vy),Gy.prototype.__getRepresentationComponent=function(t,e){return new $y(this.stage,t,e,this)};var $y=function(t){function e(e,i,r,n){var o=r||{};o.name=dn(o.name,i.type),t.call(this,e,o),this.signals=Object.assign(this.signals,{parametersChanged:new io}),this.parent=n,this.setRepresentation(i)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={type:{}};return i.type.get=function(){return"representation"},e.prototype.getType=function(){return this.repr.type},e.prototype.setRepresentation=function(t){this.disposeRepresentation(),this.repr=t,this.stage.tasks.listen(this.repr.tasks),this.updateVisibility()},e.prototype.addRepresentation=function(){},e.prototype.removeRepresentation=function(){},e.prototype.hasRepresentation=function(){},e.prototype.disposeRepresentation=function(){this.repr&&(this.stage.tasks.unlisten(this.repr.tasks),this.repr.dispose())},e.prototype.dispose=function(){this.parent&&this.parent.hasRepresentation(this)?this.parent.removeRepresentation(this):(this.disposeRepresentation(),this.signals.disposed.dispatch())},e.prototype.setVisibility=function(t){return this.visible=t,this.updateVisibility(),this.signals.visibilityChanged.dispatch(this.visible),this},e.prototype.getVisibility=function(){return this.parent?this.parent.visible&&this.visible:this.visible},e.prototype.toggleVisibility=function(){return this.setVisibility(!this.visible)},e.prototype.updateVisibility=function(){this.repr.setVisibility(this.getVisibility())},e.prototype.update=function(t){return this.repr.update(t),this},e.prototype.build=function(t){return this.repr.build(t),this},e.prototype.setSelection=function(t){return this.repr.setSelection(t),this},e.prototype.setParameters=function(t){return this.repr.setParameters(t),this.signals.parametersChanged.dispatch(this.repr.getParameters()),this},e.prototype.getParameters=function(){return this.repr.getParameters()},e.prototype.setColor=function(t){return this.repr.setColor(t),this},e.prototype.getCenter=function(){},e.prototype.getZoom=function(){},e.prototype.getBox=function(){},Object.defineProperties(e.prototype,i),e}(Gy),Hy=function(t){var e=this;this.list=t||[];for(var i=this.list.length,r=0;r<i;++r)e.list[r].signals.disposed.add(e._remove,e)};Hy.prototype._remove=function(t){var e=this.list.indexOf(t);-1!==e&&this.list.splice(e,1)},Hy.prototype._invoke=function(t,e){for(var i=this,r=this.list.length,n=0;n<r;++n){var o=i.list[n],a=o[t];"function"==typeof a&&a.apply(o,e)}return this},Hy.prototype.setVisibility=function(t){return this._invoke("setVisibility",[t])},Hy.prototype.setSelection=function(t){return this._invoke("setSelection",[t])},Hy.prototype.dispose=function(){return this._invoke("dispose")};var Wy=function(t){function e(){t.apply(this,arguments)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.addRepresentation=function(t,e){return this._invoke("addRepresentation",[t,e])},e.prototype.autoView=function(t){return this._invoke("autoView",[t])},e}(Hy),Xy=function(t){function e(){t.apply(this,arguments)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.setParameters=function(t){return this._invoke("setParameters",[t])},e.prototype.setColor=function(t){return this._invoke("setColor",[t])},e}(Hy),qy=new g,Yy=function(t,e){if(this.signals={parametersChanged:new io,fullscreenChanged:new io,componentAdded:new io,componentRemoved:new io,clicked:new io,hovered:new io},this.tasks=new Cf,this.compList=[],this.defaultFileParams={},this.viewer=new Ho(t),this.viewer.renderer){this.tooltip=document.createElement("div"),Object.assign(this.tooltip.style,{display:"none",position:"fixed",zIndex:2+(parseInt(this.viewer.container.style.zIndex)||0),pointerEvents:"none",backgroundColor:"rgba( 0, 0, 0, 0.6 )",color:"lightgrey",padding:"8px",fontFamily:"sans-serif"}),document.body.appendChild(this.tooltip),this.mouseObserver=new Xf(this.viewer.renderer.domElement),this.viewerControls=new mm(this),this.trackballControls=new im(this),this.pickingControls=new am(this),this.animationControls=new Tm(this),this.mouseControls=new Im(this),this.pickingBehavior=new Lm(this),this.mouseBehavior=new Rm(this),this.animationBehavior=new Om(this),this.spinAnimation=this.animationControls.spin(null),this.rockAnimation=this.animationControls.rock(null);var i=Object.assign({impostor:!0,quality:"medium",workerDefault:!0,sampleLevel:0,backgroundColor:"black",rotateSpeed:2,zoomSpeed:1.2,panSpeed:1,clipNear:0,clipFar:100,clipDist:10,fogNear:50,fogFar:100,cameraFov:40,cameraType:"perspective",lightColor:14540253,lightIntensity:1,ambientColor:14540253,ambientIntensity:.2,hoverTimeout:0,tooltip:!0,mousePreset:"default"},e);this.parameters={backgroundColor:{type:"color"},quality:{type:"select",options:{auto:"auto",low:"low",medium:"medium",high:"high"}},sampleLevel:{type:"range",step:1,max:5,min:-1},impostor:{type:"boolean"},workerDefault:{type:"boolean"},rotateSpeed:{type:"number",precision:1,max:10,min:0},zoomSpeed:{type:"number",precision:1,max:10,min:0},panSpeed:{type:"number",precision:1,max:10,min:0},clipNear:{type:"range",step:1,max:100,min:0},clipFar:{type:"range",step:1,max:100,min:0},clipDist:{type:"integer",max:200,min:0},fogNear:{type:"range",step:1,max:100,min:0},fogFar:{type:"range",step:1,max:100,min:0},cameraType:{type:"select",options:{perspective:"perspective",orthographic:"orthographic"}},cameraFov:{type:"range",step:1,max:120,min:15},lightColor:{type:"color"},lightIntensity:{type:"number",precision:2,max:10,min:0},ambientColor:{type:"color"},ambientIntensity:{type:"number",precision:2,max:10,min:0},hoverTimeout:{type:"integer",max:1e4,min:-1},tooltip:{type:"boolean"},mousePreset:{type:"select",options:{default:"default",pymol:"pymol",coot:"coot"}}},this.setParameters(i),this.viewer.animate()}};Yy.prototype.setParameters=function(t){var e=Object.assign({},t),i=this.parameters,r=this.viewer,n=this.trackballControls;for(var o in e)void 0!==e[o]&&i[o]&&(i[o].int&&(e[o]=parseInt(e[o])),i[o].float&&(e[o]=parseFloat(e[o])),i[o].value=e[o]);return void 0!==e.quality&&this.setQuality(e.quality),void 0!==e.impostor&&this.setImpostor(e.impostor),void 0!==e.rotateSpeed&&(n.rotateSpeed=e.rotateSpeed),void 0!==e.zoomSpeed&&(n.zoomSpeed=e.zoomSpeed),void 0!==e.panSpeed&&(n.panSpeed=e.panSpeed),void 0!==e.mousePreset&&this.mouseControls.preset(e.mousePreset),this.mouseObserver.setParameters({hoverTimeout:e.hoverTimeout}),r.setClip(e.clipNear,e.clipFar,e.clipDist),r.setFog(void 0,e.fogNear,e.fogFar),r.setCamera(e.cameraType,e.cameraFov),r.setSampling(e.sampleLevel),r.setBackground(e.backgroundColor),r.setLight(e.lightColor,e.lightIntensity,e.ambientColor,e.ambientIntensity),this.signals.parametersChanged.dispatch(this.getParameters()),this},Yy.prototype.getParameters=function(){var t=this,e={};for(var i in t.parameters)e[i]=t.parameters[i].value;return e},Yy.prototype.defaultFileRepresentation=function(e){if("structure"===e.type){e.setSelection("/0");var i,r,n,o=e.structure;if(o.biomolDict.BU1){var a=o.biomolDict.BU1;i=a.getAtomCount(o),r=a.getResidueCount(o),n=a.getInstanceCount(),e.setDefaultAssembly("BU1")}else i=o.getModelProxy(0).atomCount,r=o.getModelProxy(0).residueCount,n=1;of&&(i*=4);var s=o.atomStore.count/o.residueStore.count<2;s&&(i*=10);var c="chainname",u="RdYlBu",h=!1;if(1===o.getChainnameCount("polymer and /0")&&(c="residueindex",u="spectral",h=!0),t.Debug&&console.log(i,n,s),r/n<4)e.addRepresentation("ball+stick",{colorScheme:"element",scale:2,aspectRatio:1.5,bondScale:.3,bondSpacing:.75,quality:"auto"});else if(n>5&&i>15e3||i>7e5){var l=Math.min(1.5,Math.max(.1,2e3/(i/n)));s&&(l=Math.min(l,.15)),e.addRepresentation("surface",{sele:"polymer",surfaceType:"sas",probeRadius:1.4,scaleFactor:l,colorScheme:c,colorScale:u,colorReverse:h,useWorker:!1})}else i>25e4?e.addRepresentation("backbone",{lineOnly:!0,colorScheme:c,colorScale:u,colorReverse:h}):i>1e5?e.addRepresentation("backbone",{quality:"low",disableImpostor:!0,colorScheme:c,colorScale:u,colorReverse:h,scale:2}):i>8e4?e.addRepresentation("backbone",{colorScheme:c,colorScale:u,colorReverse:h,scale:2}):(e.addRepresentation("cartoon",{colorScheme:c,colorScale:u,colorReverse:h,scale:.7,aspectRatio:5,quality:"auto"}),i<5e4&&e.addRepresentation("base",{colorScheme:c,colorScale:u,colorReverse:h,quality:"auto"}),e.addRepresentation("ball+stick",{sele:"ligand",colorScheme:"element",scale:2,aspectRatio:1.5,bondScale:.3,bondSpacing:.75,quality:"auto"}));e.structure.frames.length&&e.addTrajectory()}else"surface"!==e.type&&"volume"!==e.type||e.addRepresentation("surface");this.tasks.onZeroOnce(this.autoView,this)},Yy.prototype.loadFile=function(t,e){var i=Object.assign({},this.defaultFileParams,e),r=new Gy(this,i);r.name=yn(t).name,this.addComponent(r);var n=this.tasks;n.increment();var o=function(t){return this.removeComponent(r),r=this.addComponentFromObject(t,i),"script"===r.type?r.run():i.defaultRepresentation&&this.defaultFileRepresentation(r),n.decrement(),r}.bind(this),a=function(t){throw r.setStatus(t),n.decrement(),t};return("dcd"===dn(i.ext,yn(t).ext)?Promise.reject("loadFile: ext 'dcd' must be loaded into a structure component"):mo(t,i)).then(o,a)},Yy.prototype.addComponent=function(t){if(!t)return void cf.warn("Stage.addComponent: no component given");this.compList.push(t),this.signals.componentAdded.dispatch(t)},Yy.prototype.addComponentFromObject=function(t,e){var i=vf.get(t.type);if(i){var r=new i(this,t,e);return this.addComponent(r),r}cf.warn("no component for object type",t.type)},Yy.prototype.removeComponent=function(t){var e=this.compList.indexOf(t);-1!==e&&(this.compList.splice(e,1),t.dispose(),this.signals.componentRemoved.dispatch(t))},Yy.prototype.removeAllComponents=function(t){this.compList.slice().forEach(function(e){t&&e.type!==t||this.removeComponent(e)},this)},Yy.prototype.handleResize=function(){this.viewer.handleResize()},Yy.prototype.setSize=function(t,e){var i=this.viewer.container;i!==document.body&&(void 0!==t&&(i.style.width=t),void 0!==e&&(i.style.height=e),this.handleResize())},Yy.prototype.toggleFullscreen=function(t){function e(){return document.fullscreenElement||document.mozFullScreenElement||document.webkitFullscreenElement||document.msFullscreenElement}function i(){if(!e()&&r.lastFullscreenElement){var t=r.lastFullscreenElement;t.style.width=t.dataset.normalWidth,t.style.height=t.dataset.normalHeight,document.removeEventListener("fullscreenchange",i),document.removeEventListener("mozfullscreenchange",i),document.removeEventListener("webkitfullscreenchange",i),document.removeEventListener("MSFullscreenChange",i),r.handleResize(),r.signals.fullscreenChanged.dispatch(!1)}}if(!(document.fullscreenEnabled||document.mozFullScreenEnabled||document.webkitFullscreenEnabled||document.msFullscreenEnabled))return void cf.log("fullscreen mode (currently) not possible");var r=this;t=t||this.viewer.container,this.lastFullscreenElement=t,e()?document.exitFullscreen?document.exitFullscreen():document.msExitFullscreen?document.msExitFullscreen():document.mozCancelFullScreen?document.mozCancelFullScreen():document.webkitExitFullscreen&&document.webkitExitFullscreen():(t.dataset.normalWidth=t.style.width,t.dataset.normalHeight=t.style.height,t.style.width=screen.width+"px",t.style.height=screen.height+"px",t.requestFullscreen?t.requestFullscreen():t.msRequestFullscreen?t.msRequestFullscreen():t.mozRequestFullScreen?t.mozRequestFullScreen():t.webkitRequestFullscreen&&t.webkitRequestFullscreen(),document.addEventListener("fullscreenchange",i),document.addEventListener("mozfullscreenchange",i),document.addEventListener("webkitfullscreenchange",i),document.addEventListener("MSFullscreenChange",i),this.handleResize(),this.signals.fullscreenChanged.dispatch(!0),setTimeout(function(){r.handleResize()},100))},Yy.prototype.setFocus=function(t){var e=Xn(t/2,0,49.9),i=100-e,r=(i-e)/2;this.setParameters({clipNear:e,clipFar:i,fogNear:qn(i-r),fogFar:qn(i+r)})},Yy.prototype.setSpin=function(t,e){this.rockAnimation.axis&&this.setRock(null),Array.isArray(t)&&(t=(new g).fromArray(t)),void 0!==t&&(this.spinAnimation.axis=t),void 0!==e&&(this.spinAnimation.angle=e)},Yy.prototype.setRock=function(t,e,i){this.spinAnimation.axis&&this.setSpin(null),Array.isArray(t)&&(t=(new g).fromArray(t)),void 0!==t&&(this.rockAnimation.axis=t),void 0!==e&&(this.rockAnimation.angleStep=e),void 0!==i&&(this.rockAnimation.angleEnd=i),this.rockAnimation.angleSum=0,this.rockAnimation.direction=1},Yy.prototype.getZoomForBox=function(t){var e=t.getSize(qy),i=Math.max(e.x,e.y,e.z),r=Math.min(e.x,e.y,e.z),n=i+Math.sqrt(r),o=Gn(this.viewer.perspectiveCamera.fov),a=this.viewer.width,s=this.viewer.height,c=a/s,u=s<a?1:c;return n=Math.abs(.5*n/u/Math.sin(o/2)),-(n+=this.parameters.clipDist.value)},Yy.prototype.getBox=function(){return this.viewer.boundingBox},Yy.prototype.getZoom=function(){return this.getZoomForBox(this.getBox())},Yy.prototype.getCenter=function(t){return this.getBox().getCenter(t)},Yy.prototype.autoView=function(t){this.animationControls.zoomMove(this.getCenter(),this.getZoom(),dn(t,0))},Yy.prototype.makeImage=function(t){var e=this.viewer,i=this.tasks;return new Promise(function(r,n){function o(){i.increment(),e.makeImage(t).then(function(t){i.decrement(),r(t)}).catch(function(t){i.decrement(),n(t)})}i.onZeroOnce(o)})},Yy.prototype.setImpostor=function(t){this.parameters.impostor.value=t;var e=["spacefill","ball+stick","licorice","hyperball","backbone","rocket","helixorient","contact","distance","dot"];this.eachRepresentation(function(i){if("script"!==i.type&&e.includes(i.getType())){var r=i.getParameters();r.disableImpostor=!t,i.build(r)}})},Yy.prototype.setQuality=function(t){this.parameters.quality.value=t;var e=["tube","cartoon","ribbon","trace","rope"],i=["spacefill","ball+stick","licorice","hyperball","backbone","rocket","helixorient","contact","distance","dot"];this.eachRepresentation(function(r){if("script"!==r.type){var n=r.getParameters();if(!e.includes(r.getType())){if(!i.includes(r.getType()))return;if(!n.disableImpostor)return void(r.repr.quality=t)}n.quality=t,r.build(n)}})},Yy.prototype.eachComponent=function(t,e){this.compList.slice().forEach(function(i,r){e&&i.type!==e||t(i,r)})},Yy.prototype.eachRepresentation=function(t,e){this.eachComponent(function(e){e.reprList.slice().forEach(function(i){t(i,e)})},e)},Yy.prototype.getComponentsByName=function(t,e){var i=[];return this.eachComponent(function(e){(void 0===t||Es(t,e))&&i.push(e)},e),new Wy(i)},Yy.prototype.getComponentsByObject=function(t){var e=[];return this.eachComponent(function(i){i[i.type]===t&&e.push(i)}),new Wy(e)},Yy.prototype.getRepresentationsByName=function(t,e){var i,r;"object"!=typeof t||t instanceof RegExp?(i=void 0,r=t):(i=t.comp,r=t.repr);var n=[];return this.eachRepresentation(function(t,e){(void 0===i||Es(i,e))&&(void 0===r||Es(r,t))&&n.push(t)},e),new Xy(n)},Yy.prototype.getAnythingByName=function(t){var e=this.getComponentsByName(t).list,i=this.getRepresentationsByName(t).list;return new Hy(e.concat(i))},Yy.prototype.dispose=function(){this.tasks.dispose()};var Zy=[[4,0,-2,-1,-2,0,-2,-1,-1,-1,-1,-2,-1,-1,-1,1,0,0,-3,-2],[0,9,-3,-4,-2,-3,-3,-1,-3,-1,-1,-3,-3,-3,-3,-1,-1,-1,-2,-2],[-2,-3,6,2,-3,-1,-1,-3,-1,-4,-3,1,-1,0,-2,0,-1,-3,-4,-3],[-1,-4,2,5,-3,-2,0,-3,1,-3,-2,0,-1,2,0,0,-1,-2,-3,-2],[-2,-2,-3,-3,6,-3,-1,0,-3,0,0,-3,-4,-3,-3,-2,-2,-1,1,3],[0,-3,-1,-2,-3,6,-2,-4,-2,-4,-3,0,-2,-2,-2,0,-2,-3,-2,-3],[-2,-3,-1,0,-1,-2,8,-3,-1,-3,-2,1,-2,0,0,-1,-2,-3,-2,2],[-1,-1,-3,-3,0,-4,-3,4,-3,2,1,-3,-3,-3,-3,-2,-1,3,-3,-1],[-1,-3,-1,1,-3,-2,-1,-3,5,-2,-1,0,-1,1,2,0,-1,-2,-3,-2],[-1,-1,-4,-3,0,-4,-3,2,-2,4,2,-3,-3,-2,-2,-2,-1,1,-2,-1],[-1,-1,-3,-2,0,-3,-2,1,-1,2,5,-2,-2,0,-1,-1,-1,1,-1,-1],[-2,-3,1,0,-3,0,1,-3,0,-3,-2,6,-2,0,0,1,0,-3,-4,-2],[-1,-3,-1,-1,-4,-2,-2,-3,-1,-3,-2,-2,7,-1,-2,-1,-1,-2,-4,-3],[-1,-3,0,2,-3,-2,0,-3,1,-2,0,0,-1,5,1,0,-1,-2,-2,-1],[-1,-3,-2,0,-3,-2,0,-3,2,-2,-1,0,-2,1,5,-1,-1,-3,-3,-2],[1,-1,0,0,-2,0,-1,-2,0,-2,-1,1,-1,0,-1,4,1,-2,-3,-2],[0,-1,-1,-1,-2,-2,-2,-1,-1,-1,-1,0,-1,-1,-1,1,5,0,-2,-2],[0,-1,-3,-2,-1,-3,-3,3,-2,1,1,-3,-2,-2,-3,-2,0,4,-3,-1],[-3,-2,-4,-3,1,-2,-2,-3,-3,-2,-1,-4,-4,-2,-3,-3,-2,-3,11,2],[-2,-2,-3,-2,3,-3,2,-1,-2,-1,-1,-2,-3,-1,-2,-2,-2,-1,2,7]],Ky=[[4,-1,-2,-2,0,-1,-1,0,-2,-1,-1,-1,-1,-2,-1,1,0,-3,-2,0,-2,-1,0],[-1,5,0,-2,-3,1,0,-2,0,-3,-2,2,-1,-3,-2,-1,-1,-3,-2,-3,-1,0,-1],[-2,0,6,1,-3,0,0,0,1,-3,-3,0,-2,-3,-2,1,0,-4,-2,-3,3,0,-1],[-2,-2,1,6,-3,0,2,-1,-1,-3,-4,-1,-3,-3,-1,0,-1,-4,-3,-3,4,1,-1],[0,-3,-3,-3,9,-3,-4,-3,-3,-1,-1,-3,-1,-2,-3,-1,-1,-2,-2,-1,-3,-3,-2],[-1,1,0,0,-3,5,2,-2,0,-3,-2,1,0,-3,-1,0,-1,-2,-1,-2,0,3,-1],[-1,0,0,2,-4,2,5,-2,0,-3,-3,1,-2,-3,-1,0,-1,-3,-2,-2,1,4,-1],[0,-2,0,-1,-3,-2,-2,6,-2,-4,-4,-2,-3,-3,-2,0,-2,-2,-3,-3,-1,-2,-1],[-2,0,1,-1,-3,0,0,-2,8,-3,-3,-1,-2,-1,-2,-1,-2,-2,2,-3,0,0,-1],[-1,-3,-3,-3,-1,-3,-3,-4,-3,4,2,-3,1,0,-3,-2,-1,-3,-1,3,-3,-3,-1],[-1,-2,-3,-4,-1,-2,-3,-4,-3,2,4,-2,2,0,-3,-2,-1,-2,-1,1,-4,-3,-1],[-1,2,0,-1,-3,1,1,-2,-1,-3,-2,5,-1,-3,-1,0,-1,-3,-2,-2,0,1,-1],[-1,-1,-2,-3,-1,0,-2,-3,-2,1,2,-1,5,0,-2,-1,-1,-1,-1,1,-3,-1,-1],[-2,-3,-3,-3,-2,-3,-3,-3,-1,0,0,-3,0,6,-4,-2,-2,1,3,-1,-3,-3,-1],[-1,-2,-2,-1,-3,-1,-1,-2,-2,-3,-3,-1,-2,-4,7,-1,-1,-4,-3,-2,-2,-1,-2],[1,-1,1,0,-1,0,0,0,-1,-2,-2,0,-1,-2,-1,4,1,-3,-2,-2,0,0,0],[0,-1,0,-1,-1,-1,-1,-2,-2,-1,-1,-1,-1,-2,-1,1,5,-2,-2,0,-1,-1,0],[-3,-3,-4,-4,-2,-2,-3,-2,-2,-3,-2,-3,-1,1,-4,-3,-2,11,2,-3,-4,-3,-2],[-2,-2,-2,-3,-2,-1,-2,-3,2,-1,-1,-2,-1,3,-3,-2,-2,2,7,-1,-3,-2,-1],[0,-3,-3,-3,-1,-2,-2,-3,-3,3,1,-2,1,-1,-2,-2,0,-3,-1,4,-3,-2,-1],[-2,-1,3,4,-3,0,1,-1,0,-3,-4,0,-3,-3,-2,0,-1,-4,-3,-3,4,1,-1],[-1,0,0,1,-3,3,4,-2,0,-3,-3,1,-1,-3,-1,0,-1,-3,-2,-2,1,4,-1],[0,-1,-1,-1,-2,-1,-1,-1,-1,-1,-1,-1,-1,-1,-2,0,0,-2,-1,-1,-1,-1,-1]],Qy=function(){return{blosum62:Cs("ARNDCQEGHILKMFPSTWYVBZ?",Ky),blosum62x:Cs("ACDEFGHIKLMNPQRSTVWY",Zy)}}(),Jy=function(t,e,i,r,n){this.seq1=t,this.seq2=e,this.gapPenalty=i||-10,this.gapExtensionPenalty=r||-1,this.substMatrix=n||"blosum62",this.substMatrix&&(this.substMatrix=Qy[this.substMatrix])};Jy.prototype.initMatrices=function(){var t=this;this.n=this.seq1.length,this.m=this.seq2.length,this.score=void 0,this.ali="",this.S=[],this.V=[],this.H=[];var e,i;for(e=0;e<=this.n;++e)for(t.S[e]=[],t.V[e]=[],t.H[e]=[],i=0;i<=this.m;++i)t.S[e][i]=0,t.V[e][i]=0,t.H[e][i]=0;for(e=0;e<=this.n;++e)t.S[e][0]=t.gap(0),t.H[e][0]=-1/0;for(i=0;i<=this.m;++i)t.S[0][i]=t.gap(0),t.V[0][i]=-1/0;this.S[0][0]=0},Jy.prototype.gap=function(t){return this.gapPenalty+t*this.gapExtensionPenalty},Jy.prototype.makeScoreFn=function(){var t,e,i=this.seq1,r=this.seq2,n=this.substMatrix;return n?function(o,a){t=i[o],e=r[a];try{return n[t][e]}catch(t){return-4}}:(cf.warn("Alignment: no subst matrix"),function(n,o){return t=i[n],e=r[o],t===e?5:-3})},Jy.prototype.calc=function(){t.Debug&&cf.time("Alignment.calc"),this.initMatrices();var e,i,r,n,o,a,s,c=this.gap(0),u=this.makeScoreFn(),h=this.gapExtensionPenalty,l=this.V,p=this.H,d=this.S,f=this.n,m=this.m;for(a=1;a<=f;++a)for(i=d[a-1],e=l[a-1],r=l[a],n=p[a],o=d[a],s=1;s<=m;++s)r[s]=Math.max(i[s]+c,e[s]+h),n[s]=Math.max(o[s-1]+c,n[s-1]+h),o[s]=Math.max(i[s-1]+u(a-1,s-1),r[s],n[s]);t.Debug&&cf.timeEnd("Alignment.calc"),t.Debug&&cf.log(this.S,this.V,this.H)},Jy.prototype.trace=function(){var e=this;t.Debug&&cf.time("Alignment.trace"),this.ali1="",this.ali2="";var i,r=this.makeScoreFn(),n=this.n,o=this.m;for(this.S[n][o]>=this.V[n][o]?(i="S",this.score=this.S[n][o]):this.V[n][o]>=this.H[n][o]?(i="V",this.score=this.V[n][o]):(i="H",this.score=this.H[n][o]),t.Debug&&cf.log("Alignment: SCORE",this.score),t.Debug&&cf.log("Alignment: S, V, H",this.S[n][o],this.V[n][o],this.H[n][o]);n>0&&o>0;)"S"===i?e.S[n][o]===e.S[n-1][o-1]+r(n-1,o-1)?(e.ali1=e.seq1[n-1]+e.ali1,e.ali2=e.seq2[o-1]+e.ali2,--n,--o,i="S"):e.S[n][o]===e.V[n][o]?i="V":e.S[n][o]===e.H[n][o]?i="H":(--n,--o):"V"===i?e.V[n][o]===e.V[n-1][o]+e.gapExtensionPenalty?(e.ali1=e.seq1[n-1]+e.ali1,e.ali2="-"+e.ali2,--n,i="V"):e.V[n][o]===e.S[n-1][o]+e.gap(0)?(e.ali1=e.seq1[n-1]+e.ali1,e.ali2="-"+e.ali2,--n,i="S"):--n:"H"===i?e.H[n][o]===e.H[n][o-1]+e.gapExtensionPenalty?(e.ali1="-"+e.ali1,e.ali2=e.seq2[o-1]+e.ali2,--o,i="H"):e.H[n][o]===e.S[n][o-1]+e.gap(0)?(e.ali1="-"+e.ali1,e.ali2=e.seq2[o-1]+e.ali2,--o,i="S"):--o:cf.error("Alignment: no matrix");for(;n>0;)e.ali1=e.seq1[n-1]+e.ali1,e.ali2="-"+e.ali2,--n;for(;o>0;)e.ali1="-"+e.ali1,e.ali2=e.seq2[o-1]+e.ali2,--o;t.Debug&&cf.timeEnd("Alignment.trace"),t.Debug&&cf.log([this.ali1,this.ali2])};var tb=function(t){function e(e){var i=this;t.call(this,e),e.scale||(this.scale="rainbow",this.reverse=dn(e.reverse,!0)),this.scalePerModel={},this.structure.eachModel(function(t){i.domain=[t.atomOffset,t.atomEnd],i.scalePerModel[t.index]=i.getScale()})}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.atomColor=function(t){return this.scalePerModel[t.modelIndex](t.index)},e}(Dd);lf.add("atomindex",tb);var eb=function(t){function e(e){if(t.call(this,e),e.scale||(this.scale="OrRd"),!e.domain){var i,r=1/0,n=-1/0;e.sele&&(i=new Selection(e.sele)),this.structure.eachAtom(function(t){var e=t.bfactor;r=Math.min(r,e),n=Math.max(n,e)},i),this.domain=[r,n]}this.bfactorScale=this.getScale()}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.atomColor=function(t){return this.bfactorScale(t.bfactor)},e}(Dd);lf.add("bfactor",eb);var ib=function(t){function e(e){t.call(this,e),e.scale||(this.scale="Spectral");var i={},r={};this.structure.eachModel(function(t){var e=0,n={};t.eachChain(function(t){void 0===n[t.chainid]&&(n[t.chainid]=e,e+=1)}),this.domain=[0,e-1],i[t.index]=n,r[t.index]=this.getScale()}.bind(this)),this.atomColor=function(t){var e=i[t.modelIndex];return r[t.modelIndex](e[t.chainid])}}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e}(Dd);lf.add("chainid",ib);var rb=function(t){function e(e){if(t.call(this,e),e.scale||(this.scale="Spectral"),e.domain){var i=this.getScale();this.atomColor=function(t){return i(t.chainIndex)}}else{var r={};this.structure.eachModel(function(t){this.domain=[t.chainOffset,t.chainEnd],r[t.index]=this.getScale()}.bind(this)),this.atomColor=function(t){return r[t.modelIndex](t.chainIndex)}}}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e}(Dd);lf.add("chainindex",rb);var nb=function(t){function e(e){t.call(this,e),e.scale||(this.scale="Spectral");var i={},r={};this.structure.eachModel(function(t){var e=0,n={};t.eachChain(function(t){void 0===n[t.chainname]&&(n[t.chainname]=e,e+=1)}),this.domain=[0,e-1],i[t.index]=n,r[t.index]=this.getScale()}.bind(this)),this.atomColor=function(t){var e=i[t.modelIndex];return r[t.modelIndex](e[t.chainname])}}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e}(Dd);lf.add("chainname",nb);var ob=function(t){function e(e){t.call(this,e),e.scale||(this.scale="RdYlBu"),this.rsrzScale=this.getScale({domain:[2,0]}),this.rsccScale=this.getScale({domain:[.678,1]});var i=e.structure.validation||{};this.rsrzDict=i.rsrzDict||{},this.rsccDict=i.rsccDict||{}}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.atomColor=function(t){var e=t.resno;t.inscode&&(e+="^"+t.inscode),t.chainname&&(e+=":"+t.chainname),e+="/"+t.modelIndex;var i=this.rsrzDict[e];if(void 0!==i)return this.rsrzScale(i);var r=this.rsccDict[e];return void 0!==r?this.rsccScale(r):9474192},e}(Dd);lf.add("densityfit",ob);var ab={ARG:{CD:.1,CZ:.5,NE:-.1},ASN:{CG:.55,OD1:-.55},ASP:{CB:-.16,CG:.36,OD1:-.6,OD2:-.6},CYS:{CB:.19,SG:-.19},GLN:{CD:.55,OE1:-.55},GLU:{CD:.36,CG:-.16,OE1:-.6,OE2:-.6},HIS:{CB:.1,CD2:.2,CE1:.45,CG:.15,ND1:.05,NE2:.05},LYS:{CE:.25,NZ:.75},MET:{CE:.06,CG:.06,SD:-.12},PTR:{C:.55,CA:.1,CZ:.25,N:-.35,O:-.55,O1P:-.85,O2P:-.85,O3P:-.85,OG1:-1.1,P:1.4},SEP:{C:.55,CA:.1,CB:.25,N:-.35,O:-.55,O1P:-.85,O2P:-.85,O3P:-.85,OG1:-1.1,P:1.4},SER:{CB:.25,OG:-.25},THR:{CB:.25,OG1:-.25},TPO:{C:.55,CA:.1,CB:.25,N:-.35,O:-.55,OG1:-1.1,O1P:-.85,O2P:-.85,O3P:-.85,P:1.4},TRP:{CD1:.06,CD2:.1,CE2:-.04,CE3:-.03,CG:-.03,NE1:-.06},TYR:{CZ:.25,OH:-.25},backbone:{C:.55,O:-.55,N:-.35,CA:.1}},sb=12,cb=1.04,ub=.25,hb=function(t){function e(e){function i(t){return t.isProtein()?ab[t.resname]&&ab[t.resname][t.atomname]||ab.backbone[t.atomname]||0:0}t.call(this,e),e.scale||(this.scale="rwb"),e.domain||(this.domain=[-.5,0,.5]);var r=this.getScale(),n=this.structure,o=new Float32Array(n.atomCount),a=[],s=[];n.eachAtom(function(t){if(o[t.index]=i(t)*t.occupancy,"N"===t.atomname){var e=Ls(t);void 0!==e&&(a.push(e),s.push(ub*t.occupancy))}});var c=this.structure.getBoundingBox();c.expandByScalar(cb);var u=Rs(a),h=new Fa(u,c),l=new Fa(this.structure.atomStore,c),p=this.atomProxy,d=new g,f=sb*sb;this.positionColor=function(t){for(var e=0,i=l.within(t.x,t.y,t.z,sb),n=0;n<i.length;n++){var a=i[n],c=o[a];if(0!==c){p.index=a,d.x=t.x-p.x,d.y=t.y-p.y,d.z=t.z-p.z;var m=d.lengthSq();m<f&&(e+=c/m)}}for(var g=h.within(t.x,t.y,t.z,sb),v=0;v<g.length;v++){var y=g[v];d.x=t.x-u.x[y],d.y=t.y-u.y[y],d.z=t.z-u.z[y];var b=d.lengthSq();b<f&&(e+=s[y]/b)}return r(e)}}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e}(Dd);lf.add("electrostatic",hb);var lb={H:16777215,HE:14286847,LI:13402367,BE:12779264,B:16758197,C:9474192,N:3166456,O:16715021,F:9494608,NE:11789301,NA:11230450,MG:9109248,AL:12560038,SI:1578e4,P:16744448,S:16777008,CL:2093087,AR:8442339,K:9388244,CA:4062976,SC:15132390,TI:12567239,V:10921643,CR:9083335,MN:10255047,FE:14706227,CO:15765664,NI:5296208,CU:13140019,ZN:8224944,GA:12750735,GE:6721423,AS:12419299,SE:16752896,BR:10889513,KR:6076625,RB:7351984,SR:65280,Y:9764863,ZR:9756896,NB:7586505,MO:5551541,TC:3907230,RU:2396047,RH:687500,PD:27013,AG:12632256,CD:16767375,IN:10909043,SN:6717568,SB:10380213,TE:13924864,I:9699476,XE:9699476,CS:5707663,BA:51456,LA:7394559,CE:16777159,PR:14286791,ND:13107143,PM:10747847,SM:9437127,EU:6422471,GD:4587463,TB:3211207,DY:2097095,HO:65436,ER:58997,TM:54354,YB:48952,LU:43812,HF:5096191,TA:5089023,W:2200790,RE:2522539,OS:2516630,IR:1528967,PT:13684960,AU:16765219,HG:12105936,TL:10900557,PB:5724513,BI:10375093,PO:11230208,AT:7688005,RN:4358806,FR:4325478,RA:32e3,AC:7384058,TH:47871,PA:41471,U:36863,NP:33023,PU:27647,AM:5528818,CM:7888099,BK:9064419,CF:10565332,ES:11739092,FM:11739066,MD:11734438,NO:12389767,LR:13041766,RF:13369433,DB:13697103,SG:14221381,BH:14680120,HS:15073326,MT:15400998,DS:16777215,RG:16777215,CN:16777215,UUT:16777215,FL:16777215,UUP:16777215,LV:16777215,UUH:16777215,D:16777152,T:16777120},pb=function(t){function e(e){var i=e||{};i.value=dn(i.value,lb.C),t.call(this,i)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.atomColor=function(t){var e=t.element;return"C"===e?this.value:lb[e]||16777215},e}(Dd);lf.add("element",pb);var db=function(t){function e(e){t.call(this,e),e.scale||(this.scale="Spectral"),e.domain||(this.domain=[0,this.structure.entityList.length-1]);var i=this.getScale();this.atomColor=function(t){return i(t.entityIndex)}}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e}(Dd);lf.add("entityindex",db);var fb=function(t){function e(){t.apply(this,arguments)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.atomColor=function(t){var e=t.entity;switch(e?e.entityType:void 0){case sg:return 8374655;case cg:return 16629894;case ug:return 12496596;case hg:return 3697840;default:return 16777113}},e}(Dd);lf.add("entitytype",fb);var mb=function(t){function e(e){t.call(this,e);var i=e.structure.validation||{};this.geoAtomDict=i.geoAtomDict||{},this.geoDict=i.geoDict||{}}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.atomColor=function(t){var e=t.resno;t.inscode&&(e+="^"+t.inscode),t.chainname&&(e+=":"+t.chainname),e+="/"+t.modelIndex;var i,r=this.geoAtomDict[e];return i=void 0!==r?Hn(r[t.atomname]||0):this.geoDict[e]||0,0===i?2188972:1===i?16703627:2===i?16018755:i>=3?10813478:9474192},e}(Dd);lf.add("geoquality",mb);var gb=function(t){function e(e){t.call(this,e),e.scale||(this.scale="RdYlGn");var i,r={};for(i in Sg)r[i]=Sg[i][0];if(!e.domain){var n,o=1/0,a=-1/0;for(i in r)n=r[i],o=Math.min(o,n),a=Math.max(a,n);this.domain=[o,0,a]}var s=this.getScale();this.atomColor=function(t){return s(r[t.resname]||Ag)}}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e}(Dd);lf.add("hydrophobicity",gb);var vb=function(t){function e(e){t.call(this,e),e.scale||(this.scale="rainbow"),e.domain||(this.domain=[0,this.structure.modelStore.count]);var i=this.getScale();this.atomColor=function(t){return i(t.modelIndex)}}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e}(Dd);lf.add("modelindex",vb);var yb=function(t){function e(){t.apply(this,arguments)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.atomColor=function(t){switch(t.residueType.moleculeType){case 1:return 3697840;case 2:return 15729279;case 3:return 12496596;case 4:return 16629894;case 5:return 12540695;case 6:return 8374655;default:return 16777113}},e}(Dd);lf.add("moleculetype",yb);var bb=function(t){function e(e){t.call(this,e),e.scale||(this.scale="PuBu"),e.domain||(this.domain=[0,1]);var i=this.getScale();this.atomColor=function(t){return i(t.occupancy)}}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e}(Dd);lf.add("occupancy",bb);var xb=function(t){function e(){t.apply(this,arguments)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.atomColor=function(){return Os()},e.prototype.volumeColor=function(){return Os()},e.prototype.positionColor=function(){return Os()},e}(Dd);lf.add("random",xb);var _b=function(t){function e(e){var i=this;if(t.call(this,e),e.scale||(this.scale="rainbow",this.reverse=dn(e.reverse,!0)),e.domain){var r=this.getScale();this.atomColor=function(t){return r(t.residueIndex)}}else{var n={};this.structure.eachChain(function(t){i.domain=[t.residueOffset,t.residueEnd],n[t.index]=i.getScale()}),this.atomColor=function(t){return n[t.chainIndex](t.residueIndex)}}}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e}(Dd);lf.add("residueindex",_b);var wb={ALA:9240460,ARG:124,ASN:16743536,ASP:10485826,CYS:16777072,GLN:16731212,GLU:6684672,GLY:16777215,HIS:7368959,ILE:19456,LEU:4546117,LYS:4671416,MET:12099650,PHE:5459026,PRO:5395026,SER:16740418,THR:12078080,TRP:5195264,TYR:9203788,VAL:16747775,ASX:16711935,GLX:16711935,ASH:16711935,GLH:16711935,A:10526975,G:16740464,I:8454143,C:16747595,T:10551200,U:16744576,DA:10526975,DG:16740464,DI:8454143,DC:16747595,DT:10551200,DU:16744576},Sb=function(t){function e(){t.apply(this,arguments)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.atomColor=function(t){return wb[t.resname]||16711935},e}(Dd);lf.add("resname",Sb);var Ab={alphaHelix:16711808,threeTenHelix:10485888,piHelix:6291584,betaStrand:16762880,betaTurn:6324479,coil:16777215,dna:11403518,rna:16580962,carbohydrate:10921722},Mb=function(t){function e(e){t.call(this,e),this.rp=this.structure.getResidueProxy()}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.atomColor=function(t){var e=t.sstruc,i=this.rp;return"h"===e?Ab.alphaHelix:"g"===e?Ab.threeTenHelix:"i"===e?Ab.piHelix:"e"===e||"b"===e?Ab.betaStrand:"t"===e?Ab.betaTurn:(i.index=t.residueIndex,i.isDna()?Ab.dna:i.isRna()?Ab.rna:i.isSaccharide()?Ab.carbohydrate:i.isProtein()||"s"===e||"l"===e?Ab.coil:8421504)},e}(Dd);lf.add("sstruc",Mb);var Pb=function(t){function e(){t.apply(this,arguments)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.atomColor=function(){return this.value},e.prototype.bondColor=function(){return this.value},e.prototype.valueColor=function(){return this.value},e.prototype.volumeColor=function(){return this.value},e}(Dd);lf.add("uniform",Pb);var Tb=function(t){function e(e){t.call(this,e),this.valueScale=this.getScale()}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.volumeColor=function(t){return this.valueScale(this.volume.data[t])},e}(Dd);lf.add("value",Tb);var Eb=function(t){function e(e){t.call(this,e);var i=this.volume;if(i&&i.inverseMatrix){var r=this.getScale(),n=i.inverseMatrix,o=i.data,a=i.nx,s=i.ny,c=a*s,u=new g;this.positionColor=function(t){u.copy(t),u.applyMatrix4(n);var e=Math.floor(u.x),i=Math.floor(u.y),h=Math.floor(u.z),l=(h*s+i)*a+e,p=l+1,d=l+a,f=l+c,m=d+1,g=f+1,v=d+c,y=v+1,b=o[l],x=o[p],_=o[d],w=o[f],S=o[m],A=o[g],M=o[v],P=o[y],T=u.x-e,E=u.y-i,C=u.z-h,I=Zn(b,x,T),L=Zn(w,A,T),R=Zn(_,S,T),O=Zn(M,P,T),D=Zn(Zn(I,R,E),Zn(L,O,E),C);return r(D)}}else{var h=this.value;this.positionColor=function(){return h}}}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.positionColor=function(){},e}(Dd);lf.add("volume",Eb);var Cb=function(t){function e(e,i,r){var n=this,o=r||{};o.name=dn(o.name,i.name),t.call(this,e,o),this.script=i,this.status="loaded",this.script.signals.nameChanged.add(function(t){n.setName(t)})}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={type:{}};return i.type.get=function(){return"script"},e.prototype.addRepresentation=function(){},e.prototype.removeRepresentation=function(){},e.prototype.run=function(){var t=this;this.setStatus("running"),this.script.call(this.stage).then(function(){t.setStatus("finished")}),this.setStatus("called")},e.prototype.dispose=function(){this.signals.disposed.dispatch()},e.prototype.setVisibility=function(){},e.prototype.getCenter=function(){},e.prototype.getZoom=function(){},e.prototype.getBox=function(){},Object.defineProperties(e.prototype,i),e}(Gy);vf.add("script",Cb);var Ib=function(t){function e(e,i,r){var n=r||{};n.name=dn(n.name,i.name),t.call(this,e,n),this.shape=i}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={type:{}};return i.type.get=function(){return"shape"},e.prototype.addRepresentation=function(e,i){return t.prototype.addRepresentation.call(this,e,this.shape,i)},e.prototype.getBoxUntransformed=function(){return this.shape.boundingBox},e.prototype.getCenterUntransformed=function(){return this.shape.center},e.prototype.dispose=function(){this.shape.dispose(),t.prototype.dispose.call(this)},Object.defineProperties(e.prototype,i),e}(Gy);vf.add("shape",Ib);var Lb=function(t){function e(e,i,r,n){var o=this,a=r||{};a.name=dn(a.name,i.name),t.call(this,e,a),this.signals=Object.assign(this.signals,{frameChanged:new io,playerChanged:new io,gotNumframes:new io,parametersChanged:new io}),this.trajectory=i,this.parent=n,this.status="loaded",this.defaultStep=dn(a.defaultStep,void 0),this.defaultTimeout=dn(a.defaultTimeout,50),this.defaultInterpolateType=dn(a.defaultInterpolateType,""),this.defaultInterpolateStep=dn(a.defaultInterpolateStep,5),this.defaultMode=dn(a.defaultMode,"loop"),this.defaultDirection=dn(a.defaultDirection,"forward"),i.signals.frameChanged.add(function(t){o.signals.frameChanged.dispatch(t)}),i.signals.playerChanged.add(function(t){o.signals.playerChanged.dispatch(t)}),i.signals.gotNumframes.add(function(t){o.signals.gotNumframes.dispatch(t)}),void 0!==a.initialFrame&&this.setFrame(a.initialFrame)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={type:{}};return i.type.get=function(){return"trajectory"},e.prototype.addRepresentation=function(e,i){return t.prototype.addRepresentation.call(this,e,this.trajectory,i)},e.prototype.setFrame=function(t){this.trajectory.setFrame(t)},e.prototype.setParameters=function(t){this.trajectory.setParameters(t),this.signals.parametersChanged.dispatch(t)},e.prototype.dispose=function(){this.trajectory.dispose(),t.prototype.dispose.call(this)},e.prototype.getCenter=function(){},Object.defineProperties(e.prototype,i),e}(Gy),Rb=function(t){function e(e,i,r){t.call(this,"",i,r),this.name=e.name,this.path=e.path,this.frames=e.coordinates,this.boxes=e.boxes}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={type:{}};return i.type.get=function(){return"frames"},e.prototype.makeAtomIndices=function(){"StructureView"===this.structure.type?this.atomIndices=this.structure.getAtomIndices():this.atomIndices=null},e.prototype._loadFrame=function(t,e){var i,r=this.frames[t];if(this.atomIndices){var n=this.atomIndices,o=n.length;i=new Float32Array(3*o);for(var a=0;a<o;++a){var s=3*a,c=3*n[a];i[s+0]=r[c+0],i[s+1]=r[c+1],i[s+2]=r[c+2]}}else i=new Float32Array(r);var u=this.boxes[t],h=this.frames.length;this.process(t,u,i,h),"function"==typeof e&&e()},e.prototype.getNumframes=function(){this.frames&&this.setNumframes(this.frames.length)},e.prototype.getPath=function(t,e){var i,r,n,o=this,a=this.numframes,s=3*t,c=new Float32Array(3*a);for(i=0;i<a;++i)r=3*i,n=o.frames[i],c[r+0]=n[s+0],c[r+1]=n[s+1],c[r+2]=n[s+2];e(c)},Object.defineProperties(e.prototype,i),e}(Cv),Ob=function(t){function e(e,i,r){t.call(this,"",i,r)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={type:{}};return i.type.get=function(){return"structure"},e.prototype.makeAtomIndices=function(){this.structure.atomSet.getSize()<this.structure.atomStore.count?this.atomIndices=this.structure.getAtomIndices():this.atomIndices=null},e.prototype._loadFrame=function(t,e){var i,r=this.structure,n=r.frames[t];if(this.atomIndices){var o=this.atomIndices,a=o.length;i=new Float32Array(3*a);for(var s=0;s<a;++s){var c=3*s,u=3*o[s];i[c+0]=n[u+0],i[c+1]=n[u+1],i[c+2]=n[u+2]}}else i=new Float32Array(n);var h=r.boxes[t],l=r.frames.length;this.process(t,h,i,l),"function"==typeof e&&e()},e.prototype.getNumframes=function(){this.setNumframes(this.structure.frames.length)},e.prototype.getPath=function(t,e){var i,r,n,o=this,a=this.numframes,s=3*t,c=new Float32Array(3*a);for(i=0;i<a;++i)r=3*i,n=o.structure.frames[i],c[r+0]=n[s+0],c[r+1]=n[s+1],c[r+2]=n[s+2];e(c)},Object.defineProperties(e.prototype,i),e}(Cv),Db=function(t){function e(){t.apply(this,arguments)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={type:{}};return i.type.get=function(){return"remote"},e.prototype.makeAtomIndices=function(){var t=[];if("StructureView"===this.structure.type){var e,i,r=this.structure.getAtomIndices(),n=r[0],o=r[0],a=r.length;for(e=1;e<a;++e)o+1<(i=r[e])&&(t.push([n,o+1]),n=i),o=i;t.push([n,o+1])}else t.push([0,this.atomCount]);this.atomIndices=t},e.prototype._loadFrame=function(t,e){var i=new XMLHttpRequest,r=pf.trajectory,n=r.getFrameUrl(this.trajPath,t),o=r.getFrameParams(this.trajPath,this.atomIndices);i.open("POST",n,!0),i.responseType="arraybuffer",i.setRequestHeader("Content-type","application/x-www-form-urlencoded"),i.addEventListener("load",function(){var r=i.response;if(!r)return void cf.error("empty arrayBuffer for '"+n+"'");var o=new Int32Array(r,0,1)[0],a=new Float32Array(r,8,9),s=new Float32Array(r,44);this.process(t,a,s,o),"function"==typeof e&&e()}.bind(this),!1),i.send(o)},e.prototype.getNumframes=function(){var t=new XMLHttpRequest,e=pf.trajectory.getNumframesUrl(this.trajPath);t.open("GET",e,!0),t.addEventListener("load",function(){this.setNumframes(parseInt(t.response))}.bind(this),!1),t.send(null)},e.prototype.getPath=function(t,e){if(this.pathCache[t])return void e(this.pathCache[t]);cf.time("loadPath");var i=new XMLHttpRequest,r=pf.trajectory.getPathUrl(this.trajPath,t);i.open("POST",r,!0),i.responseType="arraybuffer",i.setRequestHeader("Content-type","application/x-www-form-urlencoded"),i.addEventListener("load",function(){cf.timeEnd("loadPath");var n=i.response;if(!n)return void cf.error("empty arrayBuffer for '"+r+"'");var o=new Float32Array(n);this.pathCache[t]=o,e(o)}.bind(this),!1),i.send("")},Object.defineProperties(e.prototype,i),e}(Cv);Mv.prototype.getView=function(t){return new Nb(this,t)};var Nb=function(e){function i(t,i){e.call(this),this.structure=t,this.selection=i,this.center=new g,this.boundingBox=new st,this._bp=this.getBondProxy(),this._ap=this.getAtomProxy(),this._rp=this.getResidueProxy(),this._cp=this.getChainProxy(),this.selection&&this.selection.signals.stringChanged.add(this.refresh,this),this.structure.signals.refreshed.add(this.refresh,this),this.refresh()}e&&(i.__proto__=e),i.prototype=Object.create(e&&e.prototype),i.prototype.constructor=i;var r={type:{},name:{},path:{},title:{},id:{},atomSetDict:{},biomolDict:{},entityList:{},unitcell:{},frames:{},boxes:{},validation:{},bondStore:{},backboneBondStore:{},rungBondStore:{},atomStore:{},residueStore:{},chainStore:{},modelStore:{},atomMap:{},residueMap:{},bondHash:{},spatialHash:{}};return i.prototype.init=function(){},r.type.get=function(){return"StructureView"},r.name.get=function(){return this.structure.name},r.path.get=function(){return this.structure.path},r.title.get=function(){return this.structure.title},r.id.get=function(){return this.structure.id},r.atomSetDict.get=function(){return this.structure.atomSetDict},r.biomolDict.get=function(){return this.structure.biomolDict},r.entityList.get=function(){return this.structure.entityList},r.unitcell.get=function(){return this.structure.unitcell},r.frames.get=function(){return this.structure.frames},r.boxes.get=function(){return this.structure.boxes},r.validation.get=function(){return this.structure.validation},r.bondStore.get=function(){return this.structure.bondStore},r.backboneBondStore.get=function(){return this.structure.backboneBondStore},r.rungBondStore.get=function(){return this.structure.rungBondStore},r.atomStore.get=function(){return this.structure.atomStore},r.residueStore.get=function(){return this.structure.residueStore},r.chainStore.get=function(){return this.structure.chainStore},r.modelStore.get=function(){return this.structure.modelStore},r.atomMap.get=function(){return this.structure.atomMap},r.residueMap.get=function(){return this.structure.residueMap},r.bondHash.get=function(){return this.structure.bondHash},r.spatialHash.get=function(){return this.structure.spatialHash},i.prototype.refresh=function(){var e=this;t.Debug&&cf.time("StructureView.refresh"),this.atomSetCache={},this.atomSet=this.getAtomSet(this.selection,!0),this.structure.atomSet&&(this.atomSet=this.atomSet.intersection(this.structure.atomSet)),this.bondSet=this.getBondSet();for(var i in e.atomSetDict){var r=e.atomSetDict[i];e.atomSetCache["__"+i]=r.makeIntersection(e.atomSet)}this.atomCount=this.atomSet.getSize(),this.bondCount=this.bondSet.getSize(),this.boundingBox=this.getBoundingBox(),this.center=this.boundingBox.getCenter(),t.Debug&&cf.timeEnd("StructureView.refresh"),this.signals.refreshed.dispatch()},i.prototype.setSelection=function(t){this.selection=t,this.refresh()},i.prototype.getSelection=function(t){var e=[];t&&t.string&&e.push(t.string);var i=this.structure.getSelection();i&&i.string&&e.push(i.string),this.selection&&this.selection.string&&e.push(this.selection.string);var r="";return e.length>0&&(r="( "+e.join(" ) AND ( ")+" )"),new Kd(r)},i.prototype.getStructure=function(){return this.structure.getStructure()},i.prototype.eachBond=function(t,e){this.structure.eachBond(t,this.getSelection(e))},i.prototype.eachAtom=function(t,e){var i=this.getAtomProxy(),r=this.getAtomSet(e),n=this.atomStore.count;if(r.getSize()<n)r.forEach(function(e){i.index=e,t(i)});else for(var o=0;o<n;++o)i.index=o,t(i)},i.prototype.eachResidue=function(t,e){this.structure.eachResidue(t,this.getSelection(e))},i.prototype.eachResidueN=function(){console.error("StructureView.eachResidueN() not implemented")},i.prototype.eachChain=function(t,e){this.structure.eachChain(t,this.getSelection(e))},i.prototype.eachModel=function(t,e){this.structure.eachModel(t,this.getSelection(e))},i.prototype.getAtomSet=function(t,e){var i=this.structure.getAtomSet(t);return!e&&this.atomSet&&(i=i.makeIntersection(this.atomSet)),i},i.prototype.getAtomIndices=function(t){return this.structure.getAtomIndices(this.getSelection(t))},i.prototype.refreshPosition=function(){return this.structure.refreshPosition()},i.prototype.dispose=function(){this.selection&&this.selection.signals.stringChanged.remove(this.refresh,this),this.structure.signals.refreshed.remove(this.refresh,this),delete this.structure,delete this.atomSet,delete this.bondSet,delete this.atomCount,delete this.bondCount},Object.defineProperties(i.prototype,r),i}(Mv),kb=function(t){function e(e,i,r){var n=r||{};n.name=dn(n.name,i.name),t.call(this,e,n),this.signals=Object.assign(this.signals,{trajectoryAdded:new io,trajectoryRemoved:new io,defaultAssemblyChanged:new io}),this.structure=i,this.trajList=[],this.initSelection(n.sele),this.setDefaultAssembly(n.assembly||"")}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={type:{}};return i.type.get=function(){return"structure"},e.prototype.initSelection=function(t){var e=this;this.selection=new Kd(t),this.structureView=new Nb(this.structure,this.selection),this.selection.signals.stringChanged.add(function(){e.structureView.setSelection(e.selection),e.rebuildRepresentations(),e.rebuildTrajectories()})},e.prototype.setSelection=function(t){return this.selection.setString(t),this},e.prototype.setDefaultAssembly=function(t){var e=this;this.defaultAssembly=t,this.reprList.forEach(function(t){t.setParameters({defaultAssembly:e.defaultAssembly})}),this.signals.defaultAssemblyChanged.dispatch(t)},e.prototype.rebuildRepresentations=function(){this.reprList.forEach(function(t){t.build()})},e.prototype.rebuildTrajectories=function(){var t=this;this.trajList.slice().forEach(function(e){e.trajectory.setStructure(t.structureView)})},e.prototype.addRepresentation=function(e,i){var r=i||{};return r.defaultAssembly=this.defaultAssembly,t.prototype.addRepresentation.call(this,e,this.structureView,r)},e.prototype.addTrajectory=function(t,e){var i=this,r=Ds(t,this.structureView,e);r.signals.frameChanged.add(function(){i.updateRepresentations({position:!0})});var n=new Lb(this.stage,r,e,this);return this.trajList.push(n),this.signals.trajectoryAdded.dispatch(n),n},e.prototype.removeTrajectory=function(t){var e=this.trajList.indexOf(t);-1!==e&&this.trajList.splice(e,1),t.dispose(),this.signals.trajectoryRemoved.dispatch(t)},e.prototype.dispose=function(){this.trajList.slice().forEach(function(t){t.dispose()}),this.trajList.length=0,this.structure.dispose(),t.prototype.dispose.call(this)},e.prototype.autoView=function(t,e){Number.isInteger(t)&&(e=t,t=void 0),this.stage.animationControls.zoomMove(this.getCenter(t),this.getZoom(t),dn(e,0))},e.prototype.getBoxUntransformed=function(t){return t?this.structureView.getBoundingBox(new Kd(t)):this.structureView.boundingBox},e.prototype.getCenterUntransformed=function(t){return t&&"string"==typeof t?this.structure.atomCenter(new Kd(t)):this.structure.center},e.prototype.superpose=function(t,e,i,r){return Is(this.structureView,t.structureView,e,i,r),this.updateRepresentations({position:!0}),this},e.prototype.setVisibility=function(e){return t.prototype.setVisibility.call(this,e),this.trajList.forEach(function(t){t.setVisibility(e)}),this},Object.defineProperties(e.prototype,i),e}(Gy);vf.add("structure",kb);var Bb=function(t){function e(e,i,r){var n=r||{};n.name=dn(n.name,i.name),t.call(this,e,n),this.surface=i}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={type:{}};return i.type.get=function(){return"surface"},e.prototype.addRepresentation=function(e,i){return t.prototype.addRepresentation.call(this,e,this.surface,i)},e.prototype.getBoxUntransformed=function(){return this.surface.boundingBox},e.prototype.getCenterUntransformed=function(){return this.surface.center},e.prototype.dispose=function(){this.surface.dispose(),t.prototype.dispose.call(this)},Object.defineProperties(e.prototype,i),e}(Gy);vf.add("surface",Bb);var Fb=function(t){function e(e,i,r){var n=r||{};n.name=dn(n.name,i.name),t.call(this,e,n),this.volume=i}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={type:{}};return i.type.get=function(){return"volume"},e.prototype.addRepresentation=function(e,i){return t.prototype.addRepresentation.call(this,e,this.volume,i)},e.prototype.getBoxUntransformed=function(){return this.volume.boundingBox},e.prototype.getCenterUntransformed=function(){return this.volume.center},e.prototype.dispose=function(){this.volume.dispose(),t.prototype.dispose.call(this)},Object.defineProperties(e.prototype,i),e}(Gy);vf.add("volume",Fb);var zb=function(t){function e(e,i,r){t.call(this,e,i,r),this.type="axes",this.parameters=Object.assign({radius:{type:"number",precision:3,max:10,min:.001},sphereDetail:!0,radialSegments:!0,disableImpostor:!0,showAxes:{type:"boolean",rebuild:!0},showBox:{type:"boolean",rebuild:!0}},this.parameters,{assembly:null}),this.init(r)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=e||{};i.radius=dn(i.radius,.5),i.colorValue=dn(i.colorValue,"lightgreen"),this.showAxes=dn(i.showAxes,!0),this.showBox=dn(i.showBox,!1),t.prototype.init.call(this,i)},e.prototype.getPrincipalAxes=function(){var t,e=this.getAssembly();return e&&(t=e.partList[0].getSelection()),this.structureView.getPrincipalAxes(t)},e.prototype.getAxesData=function(t){var e=this.getPrincipalAxes(t),i=new tt(this.colorValue),r=0,n=0;this.showAxes&&(r+=6,n+=3),this.showBox&&(r+=8,n+=12);var o=new Float32Array(3*r),a=To(r,i.r,i.g,i.b),s=Po(r,this.radius),c=new Float32Array(3*n),u=new Float32Array(3*n),h=To(n,i.r,i.g,i.b),l=Po(n,this.radius),p=0;if(this.showAxes){var d=function(t,e){t.toArray(o,2*p),e.toArray(o,2*p+3),t.toArray(c,p),e.toArray(u,p),p+=3};d(e.begA,e.endA),d(e.begB,e.endB),d(e.begC,e.endC)}if(this.showBox){var f=new g,m=e.getProjectedScaleForAtoms(t),v=m.d1a,y=m.d2a,b=m.d3a,x=m.d1b,_=m.d2b,w=m.d3b;console.log(v,y,b,x,_,w);var S=2*p,A=function(t,i,r){f.copy(e.center).addScaledVector(e.normVecA,t).addScaledVector(e.normVecB,i).addScaledVector(e.normVecC,r),f.toArray(o,S),S+=3};A(v,y,b),A(v,y,w),A(v,_,w),A(v,_,b),A(x,_,w),A(x,_,b),A(x,y,b),A(x,y,w);var M=p,P=function(t,e){f.fromArray(o,2*p+3*t).toArray(c,M),f.fromArray(o,2*p+3*e).toArray(u,M),M+=3};P(0,1),P(0,3),P(0,6),P(1,2),P(1,7),P(2,3),P(2,4),P(3,5),P(4,5),P(4,7),P(5,6),P(6,7)}var T=new Hm(e);return{vertex:{position:o,color:a,radius:s,picking:T},edge:{position1:c,position2:u,color:h,color2:h,radius:l,picking:T}}},e.prototype.create=function(){var t=this.getAxesData(this.structureView);this.sphereBuffer=new $v(t.vertex,this.getBufferParams({sphereDetail:this.sphereDetail,disableImpostor:this.disableImpostor,dullInterior:!0})),this.cylinderBuffer=new oy(t.edge,this.getBufferParams({openEnded:!0,radialSegments:this.radialSegments,disableImpostor:this.disableImpostor,dullInterior:!0})),this.dataList.push({sview:this.structureView,bufferList:[this.sphereBuffer,this.cylinderBuffer]})},e.prototype.updateData=function(t,e){var i=this.getAxesData(e.sview),r={},n={};t&&!t.position||(r.position=i.vertex.position,n.position1=i.edge.position1,n.position2=i.edge.position2),t&&!t.color||(r.color=i.vertex.color,n.color=i.edge.color,n.color2=i.edge.color),t&&!t.radius||(r.radius=i.vertex.radius,n.radius=i.edge.radius),this.sphereBuffer.setAttributes(r),this.cylinderBuffer.setAttributes(n)},e}(ky);df.add("axes",zb);var Ub=function(t){function e(e,i,r){t.call(this,e,i,r),this.type="ball+stick",this.parameters=Object.assign({sphereDetail:!0,radialSegments:!0,openEnded:!0,disableImpostor:!0,aspectRatio:{type:"number",precision:1,max:10,min:1},lineOnly:{type:"boolean",rebuild:!0},cylinderOnly:{type:"boolean",rebuild:!0},multipleBond:{type:"select",rebuild:!0,options:{off:"off",symmetric:"symmetric",offset:"offset"}},bondScale:{type:"number",precision:2,max:1,min:.01},bondSpacing:{type:"number",precision:2,max:2,min:.5}},this.parameters),this.init(r)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=e||{};i.radius=dn(i.radius,.15),this.aspectRatio=dn(i.aspectRatio,2),this.lineOnly=dn(i.lineOnly,!1),this.cylinderOnly=dn(i.cylinderOnly,!1),this.multipleBond=dn(i.multipleBond,"off"),this.bondSpacing=dn(i.bondSpacing,1),this.bondScale=dn(i.bondScale,.4),t.prototype.init.call(this,i)},e.prototype.getAtomParams=function(e,i){return i=Object.assign({radiusParams:{radius:this.radius,scale:this.scale*this.aspectRatio}},i),t.prototype.getAtomParams.call(this,e,i)},e.prototype.getAtomData=function(t,e,i){return t.getAtomData(this.getAtomParams(e,i))},e.prototype.getBondParams=function(e,i){return i=Object.assign({multipleBond:this.multipleBond,bondSpacing:this.bondSpacing,bondScale:this.bondScale},i),t.prototype.getBondParams.call(this,e,i)},e.prototype.getBondData=function(t,e,i){return t.getBondData(this.getBondParams(e,i))},e.prototype.createData=function(t){var e=this.getBondData(t),i=[];if(this.lineOnly)this.lineBuffer=new By(e,this.getBufferParams()),i.push(this.lineBuffer);else{var r=new oy(e,this.getBufferParams({openEnded:this.openEnded,radialSegments:this.radialSegments,disableImpostor:this.disableImpostor,dullInterior:!0}));if(i.push(r),!this.cylinderOnly){var n=new $v(this.getAtomData(t),this.getBufferParams({sphereDetail:this.sphereDetail,disableImpostor:this.disableImpostor,dullInterior:!0}));i.push(n)}}return{bufferList:i}},e.prototype.updateData=function(t,e){"off"!==this.multipleBond&&t&&t.radius&&(t.position=!0);var i=this.getBondData(e.sview,t);if(this.lineOnly){var r={};t&&!t.position||(r.position1=i.position1,r.position2=i.position2),t&&!t.color||(r.color=i.color,r.color2=i.color2),e.bufferList[0].setAttributes(r)}else{var n={};if(t&&!t.position||(n.position1=i.position1,n.position2=i.position2),t&&!t.color||(n.color=i.color,n.color2=i.color2),t&&!t.radius||(n.radius=i.radius),e.bufferList[0].setAttributes(n),!this.cylinderOnly){var o=this.getAtomData(e.sview,t),a={};t&&!t.position||(a.position=o.position),t&&!t.color||(a.color=o.color),t&&!t.radius||(a.radius=o.radius),e.bufferList[1].setAttributes(a)}}},e.prototype.setParameters=function(e){var i=!1,r={};return e&&(e.aspectRatio||e.bondSpacing||e.bondScale)&&(r.radius=!0,sf&&!this.disableImpostor||(i=!0)),t.prototype.setParameters.call(this,e,r,i),this},e}(ky);df.add("ball+stick",Ub);var jb=function(t){function e(e,i,r){t.call(this,e,i,r),this.type="backbone",this.parameters=Object.assign({},this.parameters,{multipleBond:null,bondSpacing:null}),this.init(r)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=e||{};i.aspectRatio=dn(i.aspectRatio,1),i.radius=dn(i.radius,.25),t.prototype.init.call(this,i)},e.prototype.getAtomData=function(t,e,i){return t.getBackboneAtomData(this.getAtomParams(e,i))},e.prototype.getBondData=function(t,e,i){return t.getBackboneBondData(this.getBondParams(e,i))},e}(Ub);df.add("backbone",jb);var Gb=function(t){function e(e,i,r){t.call(this,e,i,r),this.type="base",this.parameters=Object.assign({},this.parameters,{multipleBond:null,bondSpacing:null})}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=e||{};i.aspectRatio=dn(i.aspectRatio,1),i.radius=dn(i.radius,.3),t.prototype.init.call(this,i)},e.prototype.getAtomData=function(t,e,i){return t.getRungAtomData(this.getAtomParams(e,i))},e.prototype.getBondData=function(t,e,i){var r=this.getBondParams(e,i);return r.colorParams.rung=!0,t.getRungBondData(r)},e}(Ub);df.add("base",Gb),ks.prototype={constructor:ks,getAtomIterator:function(t,e){function i(){var t=this.get(u);return u+=1,t}function r(i){var r=h[c%4];if(r.index=o.getAtomIndexByType(i,t),e&&i>0&&i<s&&"e"===r.sstruc){var n=l[c%4];return p.index=o.getAtomIndexByType(i+1,t),d.index=o.getAtomIndexByType(i-1,t),n.addVectors(p,d).add(r).add(r).multiplyScalar(.25),c+=1,n}return c+=1,r}function n(){c=0,u=-1}var o=this.polymer,a=o.structure,s=o.residueCount,c=0,u=-1,h=[a.getAtomProxy(),a.getAtomProxy(),a.getAtomProxy(),a.getAtomProxy()],l=[new g,new g,new g,new g],p=a.getAtomProxy(),d=a.getAtomProxy();return{size:s,next:i,get:r,reset:n}},getSubdividedColor:function(t){function e(t,e,i){c.atomColorToArray(t,e,i)}var i=this.subdiv,r=this.polymer,n=(r.residueCount-1)*i*3+3;r.isCyclic&&(n+=3*i);var o=new Float32Array(n),a=this.getAtomIterator("trace"),s=t||{};s.structure=r.structure;var c=lf.getScheme(s);return this.interpolator.getColor(a,e,o,0,r.isCyclic),{color:o}},getSubdividedPicking:function(){function t(t){return t.index}var e=this.subdiv,i=this.polymer,r=(i.residueCount-1)*e+1;i.isCyclic&&(r+=e);var n=i.structure,o=this.getAtomIterator("trace"),a=new Float32Array(r);return this.interpolator.getPicking(o,t,a,0,i.isCyclic),{picking:new $m(a,n)}},getSubdividedPosition:function(){return{position:this.getPosition()}},getSubdividedOrientation:function(){var t=this.getTangent(),e=this.getNormals(t);return{tangent:t,normal:e.normal,binormal:e.binormal}},getSubdividedSize:function(t,e){function i(t){return c.atomRadius(t)}var r=this.subdiv,n=this.polymer,o=(n.residueCount-1)*r+1;n.isCyclic&&(o+=r);var a=new Float32Array(o),s=this.getAtomIterator("trace"),c=new ga(t,e);return this.interpolator.getSize(s,i,a,0,n.isCyclic),{size:a}},getPosition:function(){var t=this.subdiv,e=this.polymer,i=(e.residueCount-1)*t*3+3;e.isCyclic&&(i+=3*t);var r=new Float32Array(i),n=this.positionIterator||this.getAtomIterator("trace",this.smoothSheet);return this.interpolator.getPosition(n,r,0,e.isCyclic),r},getTangent:function(){var t=this.subdiv,e=this.polymer,i=(this.size-1)*t*3+3;e.isCyclic&&(i+=3*t);var r=new Float32Array(i),n=this.positionIterator||this.getAtomIterator("trace",this.smoothSheet);return this.interpolator.getTangent(n,r,0,e.isCyclic),r},getNormals:function(t){var e=this.subdiv,i=this.polymer,r=i.isProtein(),n=this.size,o=(n-1)*e*3+3;i.isCyclic&&(o+=3*e);var a=new Float32Array(o),s=new Float32Array(o);if(this.directional&&!this.polymer.isCg()){var c=this.getAtomIterator("direction1"),u=this.getAtomIterator("direction2");this.interpolator.getNormalDir(c,u,t,a,s,0,i.isCyclic,r)}else this.interpolator.getNormal(n,t,a,s,0,i.isCyclic,r);return{normal:a,binormal:s}}};var Vb=new g,$b=new g,Hb=function(t){function e(e,i){var r=e||{},n=i||{},o=dn(n.radialSegments,4),a=dn(n.capped,!1),s=a?o:0,c=a?o-2:0,u=r.position.length/3,h=u*o*3+2*s*3,l=2*(u-1)*o*3+2*c*3,p=new Float32Array(h),d=new Float32Array(h),f=new Float32Array(h),m=Cn(l,h/3);t.call(this,{position:p,color:d,index:m,normal:f,picking:r.picking},n),this.aspectRatio=dn(n.aspectRatio,1),this.radialSegments=o,this.capped=a,this.capVertices=s,this.capTriangles=c,this.size2=u,r.primitiveId=Co(u),this.setAttributes(r),this.meshIndex=m,this.makeIndex()}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.setAttributes=function(t){var e,i,r,n,o,a,s,c,u,h,l,p=this.aspectRatio,d=this.size2,f=d-1,m=this.radialSegments,g=this.geometry.attributes;t.position&&(e=t.position,i=t.normal,r=t.binormal,n=t.tangent,a=t.size,c=g.position.array,h=g.normal.array,g.position.needsUpdate=!0,g.normal.needsUpdate=!0),t.color&&(o=t.color,u=g.color.array,g.color.needsUpdate=!0),t.primitiveId&&(s=t.primitiveId,l=g.primitiveId.array,g.primitiveId.needsUpdate=!0);var v,y,b,x,_,w,S,A,M,P,T,E,C,I,L,R,O,D,N,k,B,F,z,U=[],j=[],G=[],V=[],$=[],H=[];if(e)for(y=0;y<m;++y)S=y/m*2*Math.PI,U[y]=p*Math.cos(S),j[y]=Math.sin(S),G[y]=p*Math.cos(S-.01),V[y]=Math.sin(S-.01),$[y]=p*Math.cos(S+.01),H[y]=Math.sin(S+.01);for(v=0;v<d;++v)for(x=(b=3*v)*m,e&&(Vb.set(n[b],n[b+1],n[b+2]),L=i[b],R=i[b+1],O=i[b+2],D=r[b],N=r[b+1],k=r[b+2],B=e[b],F=e[b+1],z=e[b+2],I=a[v]),y=0;y<m;++y)_=x+3*y,e&&(A=-I*U[y],M=I*j[y],P=-I*G[y],T=I*V[y],E=-I*$[y],C=I*H[y],c[_]=B+A*L+M*D,c[_+1]=F+A*R+M*N,c[_+2]=z+A*O+M*k,$b.set(E*L+C*D-(P*L+T*D),E*R+C*N-(P*R+T*N),E*O+C*k-(P*O+T*k)).cross(Vb),h[_]=$b.x,h[_+1]=$b.y,h[_+2]=$b.z),o&&(u[_]=o[b],u[_+1]=o[b+1],u[_+2]=o[b+2]),s&&(l[v*m+y]=s[v]);for(b=0,x=3*d*m,y=0;y<m;++y)_=b+3*y,w=x+3*y,e&&(c[w]=c[_],c[w+1]=c[_+1],c[w+2]=c[_+2],h[w]=n[b],h[w+1]=n[b+1],h[w+2]=n[b+2]),o&&(u[w]=u[_],u[w+1]=u[_+1],u[w+2]=u[_+2]),s&&(l[d*m+y]=l[0+y]);for(b=3*(d-1)*m,x=3*(d+1)*m,y=0;y<m;++y)_=b+3*y,w=x+3*y,e&&(c[w]=c[_],c[w+1]=c[_+1],c[w+2]=c[_+2],h[w]=n[3*f],h[w+1]=n[3*f+1],h[w+2]=n[3*f+2]),o&&(u[w]=u[_],u[w+1]=u[_+1],u[w+2]=u[_+2]),s&&(l[(d+1)*m+y]=l[(d-1)*m+y])},e.prototype.makeIndex=function(){var t,e,i,r,n,o,a=this.meshIndex,s=this.size2,c=s-1,u=this.capTriangles,h=this.radialSegments,l=this.radialSegments+1;for(t=0;t<c;++t)for(e=t*h*3*2,i=t*h,r=(t+1)*h,o=0;o<h;++o)a[n=e+3*o*2]=i+o,a[n+1]=i+(o+1)%h,a[n+2]=r+o,a[n+3]=r+o,a[n+4]=i+(o+1)%h,a[n+5]=r+(o+1)%h;var p=[0];for(o=1;o<l/2;++o)p.push(o),h-o!==o&&p.push(h-o);for(n=c*h*3*2,e=s*h,o=0;o<p.length-2;++o)o%2==0?(a[n+3*o+0]=e+p[o+0],a[n+3*o+1]=e+p[o+1],a[n+3*o+2]=e+p[o+2]):(a[n+3*o+0]=e+p[o+2],a[n+3*o+1]=e+p[o+1],a[n+3*o+2]=e+p[o+0]);for(n=c*h*3*2+3*u,e=s*h+h,o=0;o<p.length-2;++o)o%2==0?(a[n+3*o+0]=e+p[o+0],a[n+3*o+1]=e+p[o+1],a[n+3*o+2]=e+p[o+2]):(a[n+3*o+0]=e+p[o+2],a[n+3*o+1]=e+p[o+1],a[n+3*o+2]=e+p[o+0])},e}(Ov),Wb=function(e){function i(t,i,r){e.call(this,t,i,r),this.type="cartoon",this.parameters=Object.assign({aspectRatio:{type:"number",precision:1,max:10,min:1},subdiv:{type:"integer",max:50,min:1,rebuild:!0},radialSegments:{type:"integer",max:50,min:1,rebuild:!0},tension:{type:"number",precision:1,max:1,min:.1},capped:{type:"boolean",rebuild:!0},smoothSheet:{type:"boolean",rebuild:!0}},this.parameters),this.init(r)}return e&&(i.__proto__=e),i.prototype=Object.create(e&&e.prototype),i.prototype.constructor=i,i.prototype.init=function(t){var i=t||{};i.colorScheme=dn(i.colorScheme,"chainname"),i.colorScale=dn(i.colorScale,"RdYlBu"),i.radius=dn(i.radius,"sstruc"),i.scale=dn(i.scale,.7),this.aspectRatio=dn(i.aspectRatio,5),this.tension=dn(i.tension,NaN),this.capped=dn(i.capped,!0),this.smoothSheet=dn(i.smoothSheet,!1),"low"===i.quality?(this.subdiv=3,this.radialSegments=6):"medium"===i.quality?this.subdiv=6:"high"===i.quality?this.subdiv=12:this.subdiv=dn(i.subdiv,6),e.prototype.init.call(this,i)},i.prototype.getSplineParams=function(t){return Object.assign({subdiv:this.subdiv,tension:this.tension,directional:1!==this.aspectRatio,smoothSheet:this.smoothSheet},t)},i.prototype.getSpline=function(t){return new ks(t,this.getSplineParams())},i.prototype.getScale=function(t){return t.isCg()?this.scale*this.aspectRatio:this.scale},i.prototype.getAspectRatio=function(t){return t.isCg()?1:this.aspectRatio},i.prototype.createData=function(t){var e=this,i=[],r=[];return this.structure.eachPolymer(function(t){if(!(t.residueCount<4)){r.push(t);var n=e.getSpline(t),o=n.getSubdividedPosition(),a=n.getSubdividedOrientation(),s=n.getSubdividedColor(e.getColorParams()),c=n.getSubdividedPicking(),u=n.getSubdividedSize(e.radius,e.getScale(t));i.push(new Hb(Object.assign({},o,a,s,c,u),e.getBufferParams({radialSegments:e.radialSegments,aspectRatio:e.getAspectRatio(t),capped:e.capped,dullInterior:!0})))}},t.getSelection()),{bufferList:i,polymerList:r}},i.prototype.updateData=function(e,i){var r=this;t.Debug&&cf.time(this.type+" repr update"),e=e||{};for(var n=0,o=i.polymerList.length;n<o;++n){var a={},s=i.polymerList[n],c=r.getSpline(s);if(i.bufferList[n].aspectRatio=r.getAspectRatio(s),e.position||e.radius){var u=c.getSubdividedPosition(),h=c.getSubdividedOrientation(),l=c.getSubdividedSize(r.radius,r.getScale(s));a.position=u.position,a.normal=h.normal,a.binormal=h.binormal,a.tangent=h.tangent,a.size=l.size}if(e.color){var p=c.getSubdividedColor(r.getColorParams());a.color=p.color}if(e.picking){var d=c.getSubdividedPicking();a.picking=d.picking}i.bufferList[n].setAttributes(a)}t.Debug&&cf.timeEnd(this.type+" repr update")},i.prototype.setParameters=function(t){var i={};return t&&t.aspectRatio&&(i.radius=!0),t&&t.tension&&(i.position=!0),e.prototype.setParameters.call(this,t,i,!1),this},i}(ky);df.add("cartoon",Wb);var Xb=function(t,e){this.sview1=t,this.sview2=e,this.kdtree2=new ts(e)};Xb.prototype.within=function(t,e){cf.time("Contact within");var i=this.kdtree2,r=this.sview1.getAtomProxy(),n=this.sview1.getAtomSet(!1),o=new Yg;this.sview1.eachAtom(function(a){for(var s=!1,c=i.nearest(a,1/0,t),u=0,h=c.length;u<h;++u){var l=c[u];r.index=l.index,a.residueIndex!==r.residueIndex&&(!e||l.distance>e)&&(s=!0,n.set(r.index),o.addBond(a,r,1))}s&&n.set(a.index)});var a=new og(o.count,!0);return cf.timeEnd("Contact within"),{atomSet:n,bondSet:a,bondStore:o}};var qb=function(t){function e(e,i,r){t.call(this,e,i,r),this.type="contact",this.parameters=Object.assign({contactType:{type:"select",rebuild:!0,options:{polar:"polar",polarBackbone:"polar backbone"}},maxDistance:{type:"number",precision:1,max:10,min:.1,rebuild:!0},maxAngle:{type:"integer",max:180,min:0,rebuild:!0},radialSegments:!0,disableImpostor:!0},this.parameters),this.init(r)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=e||{};i.radius=dn(i.radius,.25),this.contactType=dn(i.contactType,"polarBackbone"),this.maxDistance=dn(i.maxDistance,3.5),this.maxAngle=dn(i.maxAngle,40),t.prototype.init.call(this,i)},e.prototype.getContactData=function(t){return{polar:Bs,polarBackbone:Fs}[this.contactType](t,this.maxDistance,this.maxAngle)},e.prototype.getBondData=function(t,e,i){var r=t.getBondData(this.getBondParams(e,i));return r.picking&&(r.picking=new Xm(r.picking.array,r.picking.structure,i.bondStore)),r},e.prototype.createData=function(t){var e=this.getContactData(t);return{bufferList:[new oy(this.getBondData(t,void 0,{bondSet:e.bondSet,bondStore:e.bondStore}),this.getBufferParams({openEnded:!1,radialSegments:this.radialSegments,disableImpostor:this.disableImpostor,dullInterior:!0}))],bondSet:e.bondSet,bondStore:e.bondStore}},e.prototype.updateData=function(t,e){if(!t||t.position){var i=this.getContactData(e.sview);e.bondSet=i.bondSet,e.bondStore=i.bondStore}var r={bondSet:e.bondSet,bondStore:e.bondStore},n=this.getBondData(e.sview,t,r),o={};t&&!t.position||(o.position=Mo(n.position1,n.position2),o.position1=n.position1,o.position2=n.position2),t&&!t.color||(o.color=n.color1,o.color2=n.color2),t&&!t.radius||(o.radius=n.radius),e.bufferList[0].setAttributes(o)},e}(ky);df.add("contact",qb);var Yb=function(t){function e(e,i,r){t.call(this,e,i,r),this.type="distance",this.parameters=Object.assign({labelSize:{type:"number",precision:3,max:10,min:.001},labelColor:{type:"color"},labelVisible:{type:"boolean"},labelZOffset:{type:"number",precision:1,max:20,min:-20,buffer:"zOffset"},labelUnit:{type:"select",rebuild:!0,options:{"":"",angstrom:"angstrom",nm:"nm"}},atomPair:{type:"hidden",rebuild:!0},radialSegments:!0,disableImpostor:!0},this.parameters,{flatShaded:null,assembly:null}),this.init(r)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=e||{};i.radius=dn(i.radius,.15),this.fontFamily=dn(i.fontFamily,"sans-serif"),this.fontStyle=dn(i.fontStyle,"normal"),this.fontWeight=dn(i.fontWeight,"bold"),this.sdf=dn(i.sdf,"Firefox"!==nf),this.labelSize=dn(i.labelSize,2),this.labelColor=dn(i.labelColor,16777215),this.labelVisible=dn(i.labelVisible,!0),this.labelZOffset=dn(i.labelZOffset,.5),this.labelUnit=dn(i.labelUnit,""),this.atomPair=dn(i.atomPair,[]),t.prototype.init.call(this,i)},e.prototype.getDistanceData=function(t,e){var i=e.length,r=new Array(i),n=new Float32Array(3*i),o=new Kd,a=new Kd,s=new Yg,c=t.getAtomProxy(),u=t.getAtomProxy(),h=0;e.forEach(function(e,i){var l=e[0],p=e[1];if(Number.isInteger(l)&&Number.isInteger(p))c.index=l,u.index=p;else{o.setString(l),a.setString(p);var d=t.getAtomIndices(o),f=t.getAtomIndices(a);if(!d.length||!f.length)return void(h+=1);c.index=d[0],u.index=f[0]}s.addBond(c,u,1),i-=h;var m=c.distanceTo(u);switch(this.labelUnit){case"angstrom":r[i]=m.toFixed(2)+" "+String.fromCharCode(8491);break;case"nm":r[i]=(m/10).toFixed(2)+" nm";break;default:r[i]=m.toFixed(2)}var g=3*i;n[g+0]=(c.x+u.x)/2,n[g+1]=(c.y+u.y)/2,n[g+2]=(c.z+u.z)/2},this),h>0&&(i-=h,n=n.subarray(0,3*i));var l=new og(s.count,!0);return{text:r,position:n,bondSet:l,bondStore:s}},e.prototype.getBondData=function(t,e,i){var r=t.getBondData(this.getBondParams(e,i));return r.picking&&(r.picking=new Zm(r.picking.array,r.picking.structure,i.bondStore)),r},e.prototype.create=function(){if(0!==this.structureView.atomCount){var t=this.atomPair.length;if(0!==t){var e=this.getDistanceData(this.structureView,this.atomPair),i=new tt(this.labelColor);this.textBuffer=new vy({position:e.position,size:Po(t,this.labelSize),color:To(t,i.r,i.g,i.b),text:e.text},this.getBufferParams({fontFamily:this.fontFamily,fontStyle:this.fontStyle,fontWeight:this.fontWeight,sdf:this.sdf,zOffset:this.labelZOffset,opacity:1,visible:this.labelVisible}));var r={bondSet:e.bondSet,bondStore:e.bondStore},n=this.getBondData(this.structureView,void 0,r);this.cylinderBuffer=new oy(n,this.getBufferParams({openEnded:!1,radialSegments:this.radialSegments,disableImpostor:this.disableImpostor,dullInterior:!0})),this.dataList.push({sview:this.structureView,bondSet:e.bondSet,bondStore:e.bondStore,position:e.position,bufferList:[this.textBuffer,this.cylinderBuffer]})}}},e.prototype.update=function(e){e.position?this.build():t.prototype.update.call(this,e)},e.prototype.updateData=function(t,e){var i={bondSet:e.bondSet,bondStore:e.bondStore},r=this.getBondData(e.sview,t,i),n={},o={},a=this.atomPair.length;if(t.labelSize&&(o.size=Po(a,this.labelSize)),t.labelColor){var s=new tt(this.labelColor);o.color=To(a,s.r,s.g,s.b)}t.color&&(n.color=r.color,n.color2=r.color2),(t.radius||t.scale)&&(n.radius=r.radius),this.textBuffer.setAttributes(o),this.cylinderBuffer.setAttributes(n)},e.prototype.setVisibility=function(e,i){return t.prototype.setVisibility.call(this,e,!0),this.textBuffer&&this.textBuffer.setVisibility(this.labelVisible&&this.visible),i||this.viewer.requestRender(),this},e.prototype.setParameters=function(e){var i={};return e&&e.labelSize&&(i.labelSize=!0),e&&(e.labelColor||0===e.labelColor)&&(i.labelColor=!0),t.prototype.setParameters.call(this,e,i,!1),e&&void 0!==e.labelVisible&&this.setVisibility(this.visible),this},e}(ky);df.add("distance",Yb);var Zb=function(t){function e(e,i){var r=i||{},n=2*(e.position.length/3),o=new tt(dn(r.color,"grey")),a=new Float32Array(3*n),s=To(n,o.r,o.g,o.b);t.call(this,{position:a,color:s},r),this.scale=dn(r.scale,1),this.setAttributes(e)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={isLine:{},vertexShader:{},fragmentShader:{}};return e.prototype.setAttributes=function(t){var e,i,r,n=this.geometry.attributes;t.position&&t.vector&&(e=t.position,i=t.vector,r=n.position.array,n.position.needsUpdate=!0);var o,a,s=this.size/2,c=this.scale;if(t.position&&t.vector)for(var u=0;u<s;u++)a=3*u,r[(o=2*u*3)+0]=e[a+0],r[o+1]=e[a+1],r[o+2]=e[a+2],r[o+3]=e[a+0]+i[a+0]*c,r[o+4]=e[a+1]+i[a+1]*c,r[o+5]=e[a+2]+i[a+2]*c},i.isLine.get=function(){return!0},i.vertexShader.get=function(){return"Line.vert"},i.fragmentShader.get=function(){return"Line.frag"},Object.defineProperties(e.prototype,i),e}(Lv),Kb=function(e){function i(t,i,r){e.call(this,t,i,r),this.type="helixorient",this.parameters=Object.assign({sphereDetail:!0,disableImpostor:!0},this.parameters),this.init(r)}return e&&(i.__proto__=e),i.prototype=Object.create(e&&e.prototype),i.prototype.constructor=i,i.prototype.init=function(t){var i=t||{};i.colorScheme=dn(i.colorScheme,"sstruc"),i.radius=dn(i.radius,.15),i.scale=dn(i.scale,1),e.prototype.init.call(this,i)},i.prototype.createData=function(t){var e=this,i=[],r=[];return this.structure.eachPolymer(function(t){if(!(t.residueCount<4)){r.push(t);var n=new Za(t),o=n.getPosition(),a=n.getColor(e.getColorParams()),s=n.getSize(e.radius,e.scale),c=n.getPicking();i.push(new $v({position:o.center,color:a.color,radius:s.size,picking:c.picking},e.getBufferParams({sphereDetail:e.sphereDetail,disableImpostor:e.disableImpostor,dullInterior:!0})),new Zb({position:o.center,vector:o.axis},e.getBufferParams({color:"skyblue",scale:1})),new Zb({position:o.center,vector:o.resdir},e.getBufferParams({color:"lightgreen",scale:1})))}},t.getSelection()),{bufferList:i,polymerList:r}},i.prototype.updateData=function(e,i){t.Debug&&cf.time(this.type+" repr update"),e=e||{};for(var r=0,n=i.polymerList.length;r<n;++r){var o=3*r,a={},s=new Za(i.polymerList[r]);if(e.position){var c=s.getPosition();a.position=c.center,i.bufferList[o+1].setAttributes({position:c.center,vector:c.axis}),i.bufferList[o+2].setAttributes({position:c.center,vector:c.resdir})}i.bufferList[o].setAttributes(a)}t.Debug&&cf.timeEnd(this.type+" repr update")},i}(ky);df.add("helixorient",Kb);var Qb=function(t){function e(e,i,r){t.call(this,e,i,r),this.type="licorice",this.parameters=Object.assign({},this.parameters,{aspectRatio:null})}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=e||{};i.aspectRatio=1,t.prototype.init.call(this,i)},e}(Ub);df.add("licorice",Qb),mf.add("shader/HyperballStickImpostor.vert","\nattribute vec3 mapping;\nattribute float radius;\nattribute float radius2;\nattribute vec3 position1;\nattribute vec3 position2;\nvarying mat4 matrix_near;\nvarying vec4 prime1;\nvarying vec4 prime2;\nvarying float vRadius;\nvarying float vRadius2;\n#ifdef PICKING\n#include unpack_color\nattribute float primitiveId;\nvarying vec3 vPickingColor;\n#else\nattribute vec3 color2;\nvarying vec3 vColor1;\nvarying vec3 vColor2;\n#endif\nuniform float shrink;\nuniform mat4 modelViewProjectionMatrix;\nuniform mat4 modelViewProjectionMatrixInverse;\nvoid main(){\nvRadius = radius;\nvRadius2 = radius2;\nvec4 spaceposition;\nvec3 position_atom1;\nvec3 position_atom2;\nvec4 vertex_position;\n#ifdef PICKING\nvPickingColor = unpackColor( primitiveId );\n#else\nvColor1 = color;\nvColor2 = color2;\n#endif\nfloat radius1 = radius;\nposition_atom1 = position1;\nposition_atom2 = position2;\nfloat distance = distance( position_atom1, position_atom2 );\nspaceposition.z = mapping.z * distance;\nif (radius1 > radius2) {\nspaceposition.y = mapping.y * 1.5 * radius1;\nspaceposition.x = mapping.x * 1.5 * radius1;\n} else {\nspaceposition.y = mapping.y * 1.5 * radius2;\nspaceposition.x = mapping.x * 1.5 * radius2;\n}\nspaceposition.w = 1.0;\nvec4 e3 = vec4( 1.0 );\nvec3 e1, e1_temp, e2, e2_temp;\ne3.xyz = normalize(position_atom1-position_atom2);\nif (e3.z == 0.0) { e3.z = 0.0000000000001;}\nif ( (position_atom1.x - position_atom2.x) == 0.0) { position_atom1.x += 0.001;}\nif ( (position_atom1.y - position_atom2.y) == 0.0) { position_atom1.y += 0.001;}\nif ( (position_atom1.z - position_atom2.z) == 0.0) { position_atom1.z += 0.001;}\nvec4 focus = vec4( 1.0 );\nfocus.x = ( position_atom1.x*position_atom1.x - position_atom2.x*position_atom2.x +\n( radius2*radius2 - radius1*radius1 )*e3.x*e3.x/shrink )/(2.0*(position_atom1.x - position_atom2.x));\nfocus.y = ( position_atom1.y*position_atom1.y - position_atom2.y*position_atom2.y +\n( radius2*radius2 - radius1*radius1 )*e3.y*e3.y/shrink )/(2.0*(position_atom1.y - position_atom2.y));\nfocus.z = ( position_atom1.z*position_atom1.z - position_atom2.z*position_atom2.z +\n( radius2*radius2 - radius1*radius1 )*e3.z*e3.z/shrink )/(2.0*(position_atom1.z - position_atom2.z));\ne1.x = 1.0;\ne1.y = 1.0;\ne1.z = ( (e3.x*focus.x + e3.y*focus.y + e3.z*focus.z) - e1.x*e3.x - e1.y*e3.y)/e3.z;\ne1_temp = e1 - focus.xyz;\ne1 = normalize(e1_temp);\ne2_temp = e1.yzx * e3.zxy - e1.zxy * e3.yzx;\ne2 = normalize(e2_temp);\nmat3 R= mat3( e1.xyz, e2.xyz, e3.xyz );\nvertex_position.xyz = R * spaceposition.xyz;\nvertex_position.w = 1.0;\nvertex_position.x += (position_atom1.x+position_atom2.x) / 2.0;\nvertex_position.y += (position_atom1.y+position_atom2.y) / 2.0;\nvertex_position.z += (position_atom1.z+position_atom2.z) / 2.0;\ngl_Position = modelViewProjectionMatrix * vertex_position;\nvec4 i_near, i_far;\nvec4 near = gl_Position;\nnear.z = 0.0 ;\nnear = modelViewProjectionMatrixInverse * near;\ni_near = near;\nvec4 far = gl_Position;\nfar.z = far.w ;\ni_far = modelViewProjectionMatrixInverse * far;\nprime1 = vec4( position_atom1 - (position_atom1 - focus.xyz)*shrink, 1.0 );\nprime2 = vec4( position_atom2 - (position_atom2 - focus.xyz)*shrink, 1.0 );\nfloat Rsquare = (radius1*radius1/shrink) - (\n(position_atom1.x - focus.x)*(position_atom1.x - focus.x) +\n(position_atom1.y - focus.y)*(position_atom1.y - focus.y) +\n(position_atom1.z - focus.z)*(position_atom1.z - focus.z)\n);\nfocus.w = Rsquare;\nmatrix_near = mat4( i_near, i_far, focus, e3 );\ngl_Position.z = 1.0;\n}"),mf.add("shader/HyperballStickImpostor.frag","#define STANDARD\n#define IMPOSTOR\nuniform vec3 diffuse;\nuniform vec3 emissive;\nuniform float roughness;\nuniform float metalness;\nuniform float opacity;\nuniform float nearClip;\nuniform float shrink;\nuniform mat4 modelViewMatrix;\nuniform mat4 modelViewProjectionMatrix;\nuniform mat4 modelViewMatrixInverseTranspose;\nuniform mat4 projectionMatrix;\nvarying mat4 matrix_near;\nvarying vec4 prime1;\nvarying vec4 prime2;\nvarying float vRadius;\nvarying float vRadius2;\n#ifdef PICKING\nuniform float objectId;\nvarying vec3 vPickingColor;\n#else\nvarying vec3 vColor1;\nvarying vec3 vColor2;\n#include common\n#include fog_pars_fragment\n#include bsdfs\n#include lights_pars\n#include lights_physical_pars_fragment\n#endif\nbool interior = false;\nfloat calcClip( vec4 cameraPos ){\nreturn dot( cameraPos, vec4( 0.0, 0.0, 1.0, nearClip - 0.5 ) );\n}\nfloat calcClip( vec3 cameraPos ){\nreturn calcClip( vec4( cameraPos, 1.0 ) );\n}\nfloat calcDepth( in vec3 cameraPos ){\nvec2 clipZW = cameraPos.z * projectionMatrix[2].zw + projectionMatrix[3].zw;\nreturn 0.5 + 0.5 * clipZW.x / clipZW.y;\n}\nstruct Ray {\nvec3 origin ;\nvec3 direction ;\n};\nbool cutoff_plane (vec3 M, vec3 cutoff, vec3 x3){\nfloat a = x3.x;\nfloat b = x3.y;\nfloat c = x3.z;\nfloat d = -x3.x*cutoff.x-x3.y*cutoff.y-x3.z*cutoff.z;\nfloat l = a*M.x+b*M.y+c*M.z+d;\nif (l<0.0) {return true;}\nelse{return false;}\n}\nvec3 isect_surf(Ray r, mat4 matrix_coef){\nvec4 direction = vec4(r.direction, 0.0);\nvec4 origin = vec4(r.origin, 1.0);\nfloat a = dot(direction,(matrix_coef*direction));\nfloat b = dot(origin,(matrix_coef*direction));\nfloat c = dot(origin,(matrix_coef*origin));\nfloat delta =b*b-a*c;\ngl_FragColor.a = 1.0;\nif (delta<0.0){\ndiscard;\n}\nfloat t1 =(-b-sqrt(delta))/a;\nreturn r.origin+t1*r.direction;\n}\nvec3 isect_surf2(Ray r, mat4 matrix_coef){\nvec4 direction = vec4(r.direction, 0.0);\nvec4 origin = vec4(r.origin, 1.0);\nfloat a = dot(direction,(matrix_coef*direction));\nfloat b = dot(origin,(matrix_coef*direction));\nfloat c = dot(origin,(matrix_coef*origin));\nfloat delta =b*b-a*c;\ngl_FragColor.a = 1.0;\nif (delta<0.0){\ndiscard;\n}\nfloat t2 =(-b+sqrt(delta))/a;\nreturn r.origin+t2*r.direction;\n}\nRay primary_ray(vec4 near1, vec4 far1){\nvec3 near=near1.xyz/near1.w;\nvec3 far=far1.xyz/far1.w;\nreturn Ray(near,far-near);\n}\nfloat update_z_buffer(vec3 M, mat4 ModelViewP){\nfloat depth1;\nvec4 Ms=(ModelViewP*vec4(M,1.0));\nreturn depth1=(1.0+Ms.z/Ms.w)/2.0;\n}\nvoid main(){\nfloat radius = max( vRadius, vRadius2 );\nvec4 i_near, i_far, focus;\nvec3 e3, e1, e1_temp, e2;\ni_near = vec4(matrix_near[0][0],matrix_near[0][1],matrix_near[0][2],matrix_near[0][3]);\ni_far = vec4(matrix_near[1][0],matrix_near[1][1],matrix_near[1][2],matrix_near[1][3]);\nfocus = vec4(matrix_near[2][0],matrix_near[2][1],matrix_near[2][2],matrix_near[2][3]);\ne3 = vec3(matrix_near[3][0],matrix_near[3][1],matrix_near[3][2]);\ne1.x = 1.0;\ne1.y = 1.0;\ne1.z = ( (e3.x*focus.x + e3.y*focus.y + e3.z*focus.z) - e1.x*e3.x - e1.y*e3.y)/e3.z;\ne1_temp = e1 - focus.xyz;\ne1 = normalize(e1_temp);\ne2 = normalize(cross(e1,e3));\nvec4 equation = focus;\nfloat shrinkfactor = shrink;\nfloat t1 = -1.0/(1.0-shrinkfactor);\nfloat t2 = 1.0/(shrinkfactor);\nvec4 colonne1, colonne2, colonne3, colonne4;\nmat4 mat;\nvec3 equation1 = vec3(t2,t2,t1);\nfloat A1 = - e1.x*equation.x - e1.y*equation.y - e1.z*equation.z;\nfloat A2 = - e2.x*equation.x - e2.y*equation.y - e2.z*equation.z;\nfloat A3 = - e3.x*equation.x - e3.y*equation.y - e3.z*equation.z;\nfloat A11 = equation1.x*e1.x*e1.x + equation1.y*e2.x*e2.x + equation1.z*e3.x*e3.x;\nfloat A21 = equation1.x*e1.x*e1.y + equation1.y*e2.x*e2.y + equation1.z*e3.x*e3.y;\nfloat A31 = equation1.x*e1.x*e1.z + equation1.y*e2.x*e2.z + equation1.z*e3.x*e3.z;\nfloat A41 = equation1.x*e1.x*A1 + equation1.y*e2.x*A2 + equation1.z*e3.x*A3;\nfloat A22 = equation1.x*e1.y*e1.y + equation1.y*e2.y*e2.y + equation1.z*e3.y*e3.y;\nfloat A32 = equation1.x*e1.y*e1.z + equation1.y*e2.y*e2.z + equation1.z*e3.y*e3.z;\nfloat A42 = equation1.x*e1.y*A1 + equation1.y*e2.y*A2 + equation1.z*e3.y*A3;\nfloat A33 = equation1.x*e1.z*e1.z + equation1.y*e2.z*e2.z + equation1.z*e3.z*e3.z;\nfloat A43 = equation1.x*e1.z*A1 + equation1.y*e2.z*A2 + equation1.z*e3.z*A3;\nfloat A44 = equation1.x*A1*A1 + equation1.y*A2*A2 + equation1.z*A3*A3 - equation.w;\ncolonne1 = vec4(A11,A21,A31,A41);\ncolonne2 = vec4(A21,A22,A32,A42);\ncolonne3 = vec4(A31,A32,A33,A43);\ncolonne4 = vec4(A41,A42,A43,A44);\nmat = mat4(colonne1,colonne2,colonne3,colonne4);\nRay ray = primary_ray(i_near,i_far) ;\nvec3 M;\nM = isect_surf(ray, mat);\nif (cutoff_plane(M, prime1.xyz, -e3) || cutoff_plane(M, prime2.xyz, e3)){ discard; }\nvec4 M1 = vec4(M,1.0);\nvec4 M2 = mat*M1;\nvec3 _normal = ( modelViewMatrixInverseTranspose * M2 ).xyz;\ngl_FragDepthEXT = update_z_buffer(M, modelViewProjectionMatrix) ;\n#ifdef NEAR_CLIP\nif( calcClip( modelViewMatrix * vec4( M, 1.0 ) ) > 0.0 ){\nM = isect_surf2(ray, mat);\nif( calcClip( modelViewMatrix * vec4( M, 1.0 ) ) > 0.0 )\ndiscard;\ninterior = true;\ngl_FragDepthEXT = update_z_buffer(M, modelViewProjectionMatrix) ;\nif( gl_FragDepthEXT >= 0.0 ){\ngl_FragDepthEXT = max( 0.0, calcDepth( vec3( - ( nearClip - 0.5 ) ) ) + ( 0.0000001 / radius ) );\n}\n}else if( gl_FragDepthEXT <= 0.0 ){\nM = isect_surf2(ray, mat);\ninterior = true;\ngl_FragDepthEXT = update_z_buffer(M, modelViewProjectionMatrix);\nif( gl_FragDepthEXT >= 0.0 ){\ngl_FragDepthEXT = 0.0 + ( 0.0000001 / radius );\n}\n}\n#else\nif( gl_FragDepthEXT <= 0.0 ){\nM = isect_surf2(ray, mat);\ninterior = true;\ngl_FragDepthEXT = update_z_buffer(M, modelViewProjectionMatrix) ;\nif( gl_FragDepthEXT >= 0.0 ){\ngl_FragDepthEXT = 0.0 + ( 0.0000001 / radius );\n}\n}\n#endif\nif (cutoff_plane(M, prime1.xyz, -e3) || cutoff_plane(M, prime2.xyz, e3)){ discard; }\nif (gl_FragDepthEXT < 0.0)\ndiscard;\nif (gl_FragDepthEXT > 1.0)\ndiscard;\nfloat distance_ratio = ((M.x-prime2.x)*e3.x + (M.y-prime2.y)*e3.y +(M.z-prime2.z)*e3.z) /\ndistance(prime2.xyz,prime1.xyz);\n#ifdef PICKING\ngl_FragColor = vec4( vPickingColor, objectId );\n#else\nvec3 vViewPosition = -( modelViewMatrix * vec4( M, 1.0 ) ).xyz;\nvec3 vNormal = _normal;\nvec3 vColor;\nif( distance_ratio>0.5 ){\nvColor = vColor1;\n}else{\nvColor = vColor2;\n}\nvec4 diffuseColor = vec4( diffuse, opacity );\nReflectedLight reflectedLight = ReflectedLight( vec3( 0.0 ), vec3( 0.0 ), vec3( 0.0 ), vec3( 0.0 ) );\nvec3 totalEmissiveLight = emissive;\n#include color_fragment\n#include roughnessmap_fragment\n#include metalnessmap_fragment\nvec3 normal = normalize( vNormal );\nif( interior ){\nnormal = vec3( 0.0, 0.0, 0.4 );\n}\n#include lights_physical_fragment\n#include lights_template\nvec3 outgoingLight = reflectedLight.directDiffuse + reflectedLight.indirectDiffuse + reflectedLight.directSpecular + reflectedLight.indirectSpecular + totalEmissiveLight;\ngl_FragColor = vec4( outgoingLight, diffuseColor.a );\n#include premultiplied_alpha_fragment\n#include tonemapping_fragment\n#include encodings_fragment\n#include fog_fragment\n#endif\n}");var Jb=new Float32Array([-1,-1,-1,1,-1,-1,1,-1,1,-1,-1,1,-1,1,-1,1,1,-1,1,1,1,-1,1,1]),tx=new Uint16Array([0,1,2,0,2,3,1,5,6,1,6,2,4,6,5,4,7,6,0,7,4,0,3,7,0,5,1,0,4,5,3,2,6,3,6,7]),ex=function(t){function e(e,i){t.call(this,e,i);var r=e||{},n=dn((i||{}).shrink,.14);this.addUniforms({modelViewProjectionMatrix:{value:new v},modelViewProjectionMatrixInverse:{value:new v},modelViewMatrixInverseTranspose:{value:new v},shrink:{value:n}}),this.addAttributes({position1:{type:"v3",value:null},position2:{type:"v3",value:null},color2:{type:"c",value:null},radius:{type:"f",value:null},radius2:{type:"f",value:null}}),this.setAttributes(r),this.makeMapping()}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={parameters:{},isImpostor:{},vertexShader:{},fragmentShader:{}};return i.parameters.get=function(){return Object.assign.call(this,{shrink:{uniform:!0}},t.prototype.parameters)},i.isImpostor.get=function(){return!0},i.vertexShader.get=function(){return"HyperballStickImpostor.vert"},i.fragmentShader.get=function(){return"HyperballStickImpostor.frag"},Object.defineProperties(e.prototype,i),e}(function(t){function e(){t.apply(this,arguments)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={mapping:{},mappingIndices:{},mappingIndicesSize:{},mappingType:{},mappingSize:{},mappingItemSize:{}};return i.mapping.get=function(){return Jb},i.mappingIndices.get=function(){return tx},i.mappingIndicesSize.get=function(){return 36},i.mappingType.get=function(){return"v3"},i.mappingSize.get=function(){return 8},i.mappingItemSize.get=function(){return 3},Object.defineProperties(e.prototype,i),e}(zv)),ix=function(t,e){return!sf||e&&e.disableImpostor?(t.radius=Lo(t.radius1,t.radius2),new ey(t,e)):new ex(t,e)},rx=function(t){function e(e,i,r){t.call(this,e,i,r),this.type="hyperball",this.parameters=Object.assign({shrink:{type:"number",precision:3,max:1,min:.001,buffer:!0}},this.parameters,{multipleBond:null,bondSpacing:null})}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=e||{};i.scale=dn(i.scale,.2),i.radius=dn(i.radius,"vdw"),this.shrink=dn(i.shrink,.12),t.prototype.init.call(this,i)},e.prototype.getBondParams=function(e,i){return e&&!e.radius||(i=Object.assign({radius2:!0},i)),t.prototype.getBondParams.call(this,e,i)},e.prototype.createData=function(t){var e=new $v(t.getAtomData(this.getAtomParams()),this.getBufferParams({sphereDetail:this.sphereDetail,disableImpostor:this.disableImpostor,dullInterior:!0}));return this.__center=new Float32Array(3*t.bondCount),{bufferList:[e,new ix(t.getBondData(this.getBondParams()),this.getBufferParams({shrink:this.shrink,radialSegments:this.radialSegments,dullInterior:!0}))]}},e.prototype.updateData=function(t,e){var i=e.sview.getAtomData(this.getAtomParams()),r=e.sview.getBondData(this.getBondParams()),n={},o={};if(!t||t.position){n.position=i.position;var a=r.position1,s=r.position2;o.position=Mo(a,s,this.__center),o.position1=a,o.position2=s}t&&!t.color||(n.color=i.color,o.color=r.color1,o.color2=r.color2),t&&!t.radius||(n.radius=i.radius,o.radius=r.radius1,o.radius2=r.radius2),e.bufferList[0].setAttributes(n),e.bufferList[1].setAttributes(o)},e}(Qb);df.add("hyperball",rx),zs.prototype={constructor:zs,atomLabel:function(t){var e;switch(this.type){case"atomname":e=t.atomname;break;case"atomindex":e=""+t.index;break;case"occupancy":e=t.occupancy.toFixed(2);break;case"bfactor":e=t.bfactor.toFixed(2);break;case"serial":e=""+t.serial;break;case"element":e=t.element;break;case"atom":e=t.atomname+"|"+t.index;break;case"resname":e=t.resname;break;case"resno":e=""+t.resno;break;case"res":var i=t.resname.toUpperCase();e=(Mg[i]||i)+t.resno;break;case"text":e=this.text[t.index];break;default:e=t.qualifiedName()}return void 0===e?"":e}},zs.types={"":"",atomname:"atom name",atomindex:"atom index",occupancy:"occupancy",bfactor:"b-factor",serial:"serial",element:"element",atom:"atom name + index",resname:"residue name",resno:"residue no",res:"residue name + no",text:"text",qualified:"qualified name"};var nx=function(t){function e(e,i,r){t.call(this,e,i,r),this.type="label",this.parameters=Object.assign({labelType:{type:"select",options:zs.types,rebuild:!0},labelText:{type:"hidden",rebuild:!0},fontFamily:{type:"select",options:{"sans-serif":"sans-serif",monospace:"monospace",serif:"serif"},buffer:!0},fontStyle:{type:"select",options:{normal:"normal",italic:"italic"},buffer:!0},fontWeight:{type:"select",options:{normal:"normal",bold:"bold"},buffer:!0},sdf:{type:"boolean",buffer:!0},xOffset:{type:"number",precision:1,max:20,min:-20,buffer:!0},yOffset:{type:"number",precision:1,max:20,min:-20,buffer:!0},zOffset:{type:"number",precision:1,max:20,min:-20,buffer:!0},attachment:{type:"select",options:{"bottom-left":"bottom-left","bottom-center":"bottom-center","bottom-right":"bottom-right","middle-left":"middle-left","middle-center":"middle-center","middle-right":"middle-right","top-left":"top-left","top-center":"top-center","top-right":"top-right"},rebuild:!0},showBorder:{type:"boolean",buffer:!0},borderColor:{type:"color",buffer:!0},borderWidth:{type:"number",precision:2,max:.3,min:0,buffer:!0},showBackground:{type:"boolean",rebuild:!0},backgroundColor:{type:"color",buffer:!0},backgroundMargin:{type:"number",precision:2,max:2,min:0,rebuild:!0},backgroundOpacity:{type:"range",step:.01,max:1,min:0,buffer:!0}},this.parameters,{side:null,flatShaded:null,wireframe:null,linewidth:null,roughness:null,metalness:null,diffuse:null}),this.init(r)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=e||{};this.labelType=dn(i.labelType,"res"),this.labelText=dn(i.labelText,{}),this.fontFamily=dn(i.fontFamily,"sans-serif"),this.fontStyle=dn(i.fontStyle,"normal"),this.fontWeight=dn(i.fontWeight,"bold"),this.sdf=dn(i.sdf,"Chrome"===nf),this.xOffset=dn(i.xOffset,0),this.yOffset=dn(i.yOffset,0),this.zOffset=dn(i.zOffset,.5),this.attachment=dn(i.attachment,"bottom-left"),this.showBorder=dn(i.showBorder,!1),this.borderColor=dn(i.borderColor,"lightgrey"),this.borderWidth=dn(i.borderWidth,.15),this.showBackground=dn(i.showBackground,!1),this.backgroundColor=dn(i.backgroundColor,"lightgrey"),this.backgroundMargin=dn(i.backgroundMargin,.5),this.backgroundOpacity=dn(i.backgroundOpacity,1),t.prototype.init.call(this,i)},e.prototype.createData=function(t){var e={position:!0,color:!0,radius:!0},i=t.getAtomData(this.getAtomParams(e)),r=[],n=new zs(this.labelType,this.labelText);return t.eachAtom(function(t){r.push(n.atomLabel(t))}),{bufferList:[new vy({position:i.position,size:i.radius,color:i.color,text:r},this.getBufferParams({fontFamily:this.fontFamily,fontStyle:this.fontStyle,fontWeight:this.fontWeight,sdf:this.sdf,xOffset:this.xOffset,yOffset:this.yOffset,zOffset:this.zOffset,attachment:this.attachment,showBorder:this.showBorder,borderColor:this.borderColor,borderWidth:this.borderWidth,showBackground:this.showBackground,backgroundColor:this.backgroundColor,backgroundMargin:this.backgroundMargin,backgroundOpacity:this.backgroundOpacity}))]}},e.prototype.updateData=function(t,e){var i=e.sview.getAtomData(this.getAtomParams(t)),r={};t&&!t.position||(r.position=i.position),t&&!t.radius||(r.size=i.radius),t&&!t.color||(r.color=i.color),e.bufferList[0].setAttributes(r)},e}(ky);df.add("label",nx);var ox=function(t){function e(e,i,r){t.call(this,e,i,r),this.type="line",this.parameters=Object.assign({multipleBond:{type:"select",rebuild:!0,options:{off:"off",symmetric:"symmetric",offset:"offset"}},bondSpacing:{type:"number",precision:2,max:2,min:.5}},this.parameters,{flatShaded:null,side:null,wireframe:null,roughness:null,metalness:null,diffuse:null}),this.init(r)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=e||{};this.multipleBond=dn(i.multipleBond,"off"),this.bondSpacing=dn(i.bondSpacing,1),t.prototype.init.call(this,i)},e.prototype.getBondParams=function(e,i){return i=Object.assign({multipleBond:this.multipleBond,bondSpacing:this.bondSpacing,radiusParams:{radius:.1,scale:1}},i),t.prototype.getBondParams.call(this,e,i)},e.prototype.createData=function(t){var e={position:!0,color:!0},i=t.getBondData(this.getBondParams(e));return{bufferList:[new By(i,this.getBufferParams())]}},e.prototype.updateData=function(t,e){var i=e.sview.getBondData(this.getBondParams(t)),r={};t&&!t.position||(r.position1=i.position1,r.position2=i.position2),t&&!t.color||(r.color=i.color,r.color2=i.color2),e.bufferList[0].setAttributes(r)},e.prototype.setParameters=function(e){var i={};return e&&e.bondSpacing&&(i.position=!0),t.prototype.setParameters.call(this,e,i,!1),this},e}(ky);df.add("line",ox),js.__deps=[qa,Xa,Ya,Qo,Us],Vs.__deps=[qa,Ya,Po,Qo,ca,ra,ua,Gs,dn],hf.add("molsurf",function(t,e){var i=t.data.args,r=t.data.params;if(i&&r){var n=new("av"===r.type?Vs:js)(i.coordList,i.radiusList,i.indexList).getSurface(r.type,r.probeRadius,r.scaleFactor,r.cutoff,!0,r.smooth,r.contour),o=[n.position.buffer,n.index.buffer];n.normal&&o.push(n.normal.buffer),n.atomindex&&o.push(n.atomindex.buffer),e({sd:n,p:r},o)}},[js,Vs]);var ax=function(t){this.structure=t};ax.prototype._getAtomData=function(){return this.structure.getAtomData({what:{position:!0,radius:!0,index:!0},radiusParams:{radius:"vdw",scale:1}})},ax.prototype._makeSurface=function(t,e){var i=new jg(e.name,"",t);return i.info.type=e.type,i.info.probeRadius=e.probeRadius,i.info.scaleFactor=e.scaleFactor,i.info.smooth=e.smooth,i.info.cutoff=e.cutoff,i},ax.prototype.getSurface=function(t){var e=t||{},i=this._getAtomData(),r=i.position,n=i.radius,o=i.index,a=new("av"===e.type?Vs:js)(r,n,o).getSurface(e.type,e.probeRadius,e.scaleFactor,e.cutoff,!0,e.smooth,e.contour);return this._makeSurface(a,e)},ax.prototype.getSurfaceWorker=function(t,e){var i=this,r=Object.assign({},t);if(window.Worker){void 0===this.worker&&(this.worker=new za("molsurf"));var n=this._getAtomData(),o=n.position,a=n.radius,s=n.index,c={args:{coordList:o,radiusList:a,indexList:s},params:r},u=[o.buffer,a.buffer,s.buffer];this.worker.post(c,u,function(t){e(i._makeSurface(t.data.sd,r))},function(t){console.warn("MolecularSurface.getSurfaceWorker error - trying without worker",t),i.worker.terminate(),i.worker=void 0;var n=i.getSurface(r);e(n)})}else{var h=this.getSurface(r);e(h)}},ax.prototype.dispose=function(){this.worker&&this.worker.terminate()};var sx=function(t){function e(e,i,r){t.call(this,e,i,r),this.type="surface",this.parameters=Object.assign({surfaceType:{type:"select",rebuild:!0,options:{vws:"vws",sas:"sas",ms:"ms",ses:"ses",av:"av"}},probeRadius:{type:"number",precision:1,max:20,min:0,rebuild:!0},smooth:{type:"integer",precision:1,max:10,min:0,rebuild:!0},scaleFactor:{type:"number",precision:1,max:5,min:0,rebuild:!0},cutoff:{type:"number",precision:2,max:50,min:0,rebuild:!0},contour:{type:"boolean",rebuild:!0},background:{type:"boolean",rebuild:!0},opaqueBack:{type:"boolean",buffer:!0},filterSele:{type:"text",rebuild:!0},colorVolume:{type:"hidden"},useWorker:{type:"boolean",rebuild:!0}},this.parameters,{radiusType:null,radius:null,scale:null}),this.__infoList=[],this.structure.signals.refreshed.add(function(){this.__forceNewMolsurf=!0},this),this.init(r)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=e||{};i.colorScheme=dn(i.colorScheme,"uniform"),i.colorValue=dn(i.colorValue,14540253),this.surfaceType=dn(i.surfaceType,"ms"),this.probeRadius=dn(i.probeRadius,1.4),this.smooth=dn(i.smooth,2),this.scaleFactor=dn(i.scaleFactor,2),this.cutoff=dn(i.cutoff,0),this.contour=dn(i.contour,!1),this.background=dn(i.background,!1),this.opaqueBack=dn(i.opaqueBack,!0),this.filterSele=dn(i.filterSele,""),this.colorVolume=dn(i.colorVolume,void 0),this.useWorker=dn(i.useWorker,!0),t.prototype.init.call(this,e)},e.prototype.prepareData=function(t,e,i){var r=this.__infoList[e];if(r||(r={},this.__infoList[e]=r),r.molsurf&&r.sele===t.selection.string)i(e);else{if(this.filterSele){var n=t.structure.getView(new Kd(this.filterSele)),o=n.boundingBox.getSize(),a=Math.max(o.x,o.y,o.z),s=t.getAtomSetWithinPoint(n.center,a/2+6);t=t.getView(new Kd(t.getAtomSetWithinSelection(s,3).toSeleString()))}r.sele=t.selection.string,r.molsurf=new ax(t);var c=this.getSurfaceParams(),u=function(t){r.surface=t,i(e)};this.useWorker?r.molsurf.getSurfaceWorker(c,u):u(r.molsurf.getSurface(c))}},e.prototype.prepare=function(t){var e=this;if((this.__forceNewMolsurf||this.__sele!==this.selection.string||this.__surfaceParams!==JSON.stringify(this.getSurfaceParams()))&&(this.__infoList.forEach(function(t){t.molsurf.dispose()}),this.__infoList.length=0),0===this.structureView.atomCount)return void t();var i=function(){this.__sele=this.selection.string,this.__surfaceParams=JSON.stringify(this.getSurfaceParams()),this.__forceNewMolsurf=!1,t()}.bind(this),r="default"===this.assembly?this.defaultAssembly:this.assembly,n=this.structure.biomolDict[r];n?n.partList.forEach(function(t,r){var o=t.getView(e.structureView);e.prepareData(o,r,function(t){t===n.partList.length-1&&i()})}):this.prepareData(this.structureView,0,i)},e.prototype.createData=function(t,e){var i=this.__infoList[e],r=i.surface,n={position:r.getPosition(),color:r.getColor(this.getColorParams()),index:r.getFilteredIndex(this.filterSele,t)},o=[];if(r.contour){var a=new Ty(n,this.getBufferParams({wireframe:!1}));o.push(a)}else{n.normal=r.getNormal(),n.picking=r.getPicking(t.getStructure());var s=new Ay(n,this.getBufferParams({background:this.background,opaqueBack:this.opaqueBack,dullInterior:!1})),c=new My(s);o.push(c)}return{bufferList:o,info:i}},e.prototype.updateData=function(t,e){var i={};if(t.position)return this.__forceNewMolsurf=!0,void this.build();t.color&&(i.color=e.info.surface.getColor(this.getColorParams())),t.index&&(i.index=e.info.surface.getFilteredIndex(this.filterSele,e.sview)),e.bufferList[0].setAttributes(i)},e.prototype.setParameters=function(e,i,r){return i=i||{},e&&e.filterSele&&(i.index=!0),e&&void 0!==e.colorVolume&&(i.color=!0),e&&e.wireframe&&(e.contour||void 0===e.contour&&this.contour)&&(e.wireframe=!1),t.prototype.setParameters.call(this,e,i,r),this},e.prototype.getSurfaceParams=function(t){return Object.assign({type:this.surfaceType,probeRadius:this.probeRadius,scaleFactor:this.scaleFactor,smooth:this.smooth&&!this.contour,cutoff:this.cutoff,contour:this.contour,useWorker:this.useWorker},t)},e.prototype.getColorParams=function(){var e=t.prototype.getColorParams.call(this);return e.volume=this.colorVolume,e},e.prototype.clear=function(){t.prototype.clear.call(this)},e.prototype.dispose=function(){this.__infoList.forEach(function(t){t.molsurf.dispose()}),this.__infoList.length=0,t.prototype.dispose.call(this)},e}(ky);df.add("surface",sx);var cx=function(t){function e(e,i,r){t.call(this,e,i,r),this.type="point",this.parameters=Object.assign({pointSize:{type:"number",precision:1,max:100,min:0,buffer:!0},sizeAttenuation:{type:"boolean",buffer:!0},sortParticles:{type:"boolean",rebuild:!0},useTexture:{type:"boolean",buffer:!0},alphaTest:{type:"range",step:.001,max:1,min:0,buffer:!0},forceTransparent:{type:"boolean",buffer:!0},edgeBleach:{type:"range",step:.001,max:1,min:0,buffer:!0}},this.parameters,{flatShaded:null,wireframe:null,linewidth:null,roughness:null,metalness:null}),this.init(r)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=e||{};this.pointSize=dn(i.pointSize,1),this.sizeAttenuation=dn(i.sizeAttenuation,!0),this.sortParticles=dn(i.sortParticles,!1),this.useTexture=dn(i.useTexture,!1),this.alphaTest=dn(i.alphaTest,.5),this.forceTransparent=dn(i.forceTransparent,!1),this.edgeBleach=dn(i.edgeBleach,0),t.prototype.init.call(this,i)},e.prototype.createData=function(t){var e={position:!0,color:!0,picking:!0},i=t.getAtomData(this.getAtomParams(e));return{bufferList:[new Cy(i,this.getBufferParams({pointSize:this.pointSize,sizeAttenuation:this.sizeAttenuation,sortParticles:this.sortParticles,useTexture:this.useTexture,alphaTest:this.alphaTest,forceTransparent:this.forceTransparent,edgeBleach:this.edgeBleach}))]}},e.prototype.updateData=function(t,e){var i=e.sview.getAtomData(this.getAtomParams(t)),r={};t&&!t.position||(r.position=i.position),t&&!t.color||(r.color=i.color),e.bufferList[0].setAttributes(r)},e}(ky);df.add("point",cx),mf.add("shader/Ribbon.vert","#define STANDARD\nuniform float nearClip;\nuniform vec3 clipCenter;\n#if defined( NEAR_CLIP ) || defined( RADIUS_CLIP ) || !defined( PICKING )\nvarying vec3 vViewPosition;\n#endif\n#if defined( RADIUS_CLIP )\nvarying vec3 vClipCenter;\n#endif\nattribute vec3 dir;\nattribute float size;\n#ifdef PICKING\n#include unpack_color\nattribute float primitiveId;\nvarying vec3 vPickingColor;\n#else\n#include color_pars_vertex\n#ifndef FLAT_SHADED\nvarying vec3 vNormal;\n#endif\n#endif\n#include common\nvoid main(void){\n#ifdef PICKING\nvPickingColor = unpackColor( primitiveId );\n#else\n#include color_vertex\n#include beginnormal_vertex\n#include defaultnormal_vertex\n#ifndef FLAT_SHADED\nvNormal = normalize( transformedNormal );\n#endif\n#endif\n#include begin_vertex\ntransformed += normalize( dir ) * size;\n#include project_vertex\n#if defined( NEAR_CLIP ) || defined( RADIUS_CLIP ) || !defined( PICKING )\nvViewPosition = -mvPosition.xyz;\n#endif\n#if defined( RADIUS_CLIP )\nvClipCenter = -( modelViewMatrix * vec4( clipCenter, 1.0 ) ).xyz;\n#endif\n#include nearclip_vertex\n}");var ux=new Uint16Array([0,1,2,1,3,2]),hx=function(t){function e(e,i){var r=e||{},n=r.position.length/3-1,o=4*n,a=3*o,s=new Float32Array(a),c=new Float32Array(a),u=new Float32Array(a),h=Cn(a,a/3);t.call(this,{position:s,color:c,index:h,normal:u,picking:r.picking},i),this.addAttributes({dir:{type:"v3",value:new Float32Array(a)}}),this.addAttributes({size:{type:"f",value:new Float32Array(o)}}),r.primitiveId=Co(n),this.setAttributes(r),this.meshIndex=h,this.makeIndex()}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={vertexShader:{}};return e.prototype.setAttributes=function(t){var e,i,r,n,o,a,s,c,u,h,l,p,d=this.size/4,f=this.geometry.attributes;t.position&&(e=t.position,s=f.position.array,f.position.needsUpdate=!0),t.normal&&(i=t.normal,c=f.normal.array,f.normal.needsUpdate=!0),t.size&&(r=t.size,u=f.size.array,f.size.needsUpdate=!0),t.dir&&(n=t.dir,h=f.dir.array,f.dir.needsUpdate=!0),t.color&&(o=t.color,l=f.color.array,f.color.needsUpdate=!0),t.primitiveId&&(a=t.primitiveId,p=f.primitiveId.array,f.primitiveId.needsUpdate=!0);var m,g,v,y,b,x,_,w=r?r[0]:null;for(m=0;m<d;++m){for(x=3*m,v=3*m*4,b=4*m,e&&(s[v]=s[v+3]=e[x],s[v+1]=s[v+4]=e[x+1],s[v+2]=s[v+5]=e[x+2],s[v+6]=s[v+9]=e[x+3],s[v+7]=s[v+10]=e[x+4],s[v+8]=s[v+11]=e[x+5]),i&&(c[v]=c[v+3]=-i[x],c[v+1]=c[v+4]=-i[x+1],c[v+2]=c[v+5]=-i[x+2],c[v+6]=c[v+9]=-i[x+3],c[v+7]=c[v+10]=-i[x+4],c[v+8]=c[v+11]=-i[x+5]),g=0;g<4;++g)y=v+3*g,o&&(l[y]=o[x],l[y+1]=o[x+1],l[y+2]=o[x+2]),a&&(p[b+g]=a[m]);r&&(_=r[m],w!==r[m]?(u[b]=w,u[b+1]=w,u[b+2]=_,u[b+3]=_):(u[b]=_,u[b+1]=_,u[b+2]=_,u[b+3]=_),w=_),n&&(h[v]=n[x],h[v+1]=n[x+1],h[v+2]=n[x+2],h[v+3]=-n[x],h[v+4]=-n[x+1],h[v+5]=-n[x+2],h[v+6]=n[x+3],h[v+7]=n[x+4],h[v+8]=n[x+5],h[v+9]=-n[x+3],h[v+10]=-n[x+4],h[v+11]=-n[x+5])}},e.prototype.makeIndex=function(){var t,e,i,r,n=this.meshIndex,o=n.length/4/3;for(e=0;e<o;++e)for(i=6*e,r=4*e,n.set(ux,i),t=0;t<6;++t)n[i+t]+=r},i.vertexShader.get=function(){return"Ribbon.vert"},Object.defineProperties(e.prototype,i),e}(Ov),lx=function(t){function e(e,i,r){t.call(this,e,i,r),this.type="ribbon",this.parameters=Object.assign({subdiv:{type:"integer",max:50,min:1,rebuild:!0},tension:{type:"number",precision:1,max:1,min:.1},smoothSheet:{type:"boolean",rebuild:!0}},this.parameters,{side:null,wireframe:null,linewidth:null}),this.init(r)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=e||{};i.colorScheme=dn(i.colorScheme,"chainname"),i.colorScale=dn(i.colorScale,"RdYlBu"),i.radius=dn(i.radius,"sstruc"),i.scale=dn(i.scale,4),"low"===i.quality?this.subdiv=3:"medium"===i.quality?this.subdiv=6:"high"===i.quality?this.subdiv=12:this.subdiv=dn(i.subdiv,6),this.tension=dn(i.tension,NaN),this.smoothSheet=dn(i.smoothSheet,!1),t.prototype.init.call(this,i)},e.prototype.getSplineParams=function(t){return Object.assign({subdiv:this.subdiv,tension:this.tension,directional:!0,smoothSheet:this.smoothSheet},t)},e.prototype.createData=function(t){var e=this,i=[],r=[];return this.structure.eachPolymer(function(t){if(!(t.residueCount<4)){r.push(t);var n=new ks(t,e.getSplineParams()),o=n.getSubdividedPosition(),a=n.getSubdividedOrientation(),s=n.getSubdividedColor(e.getColorParams()),c=n.getSubdividedPicking(),u=n.getSubdividedSize(e.radius,e.scale);i.push(new hx({position:o.position,normal:a.binormal,dir:a.normal,color:s.color,size:u.size,picking:c.picking},e.getBufferParams()))}},t.getSelection()),{bufferList:i,polymerList:r}},e.prototype.updateData=function(t,e){var i=this;t=t||{};var r=0,n=e.polymerList.length;for(r=0;r<n;++r){var o={},a=new ks(e.polymerList[r],i.getSplineParams());if(t.position){var s=a.getSubdividedPosition(),c=a.getSubdividedOrientation();o.position=s.position,o.normal=c.binormal,o.dir=c.normal}if(t.radius||t.scale){var u=a.getSubdividedSize(i.radius,i.scale);o.size=u.size}if(t.color){var h=a.getSubdividedColor(i.getColorParams());o.color=h.color}e.bufferList[r].setAttributes(o)}},e.prototype.setParameters=function(e){var i={};return e&&e.tension&&(i.position=!0),t.prototype.setParameters.call(this,e,i,!1),this},e}(ky);df.add("ribbon",lx);var px=function(t){function e(e,i,r){t.call(this,e,i,r),this.type="rocket",this.parameters=Object.assign({localAngle:{type:"integer",max:180,min:0,rebuild:!0},centerDist:{type:"number",precision:1,max:10,min:0,rebuild:!0},ssBorder:{type:"boolean",rebuild:!0},radialSegments:!0,openEnded:!0,disableImpostor:!0},this.parameters),this.helixbundleList=[],this.init(r)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=e||{};i.colorScheme=dn(i.colorScheme,"sstruc"),i.radius=dn(i.radius,1.5),i.scale=dn(i.scale,1),i.openEnded=dn(i.openEnded,!1),this.localAngle=dn(i.localAngle,30),this.centerDist=dn(i.centerDist,2.5),this.ssBorder=dn(i.ssBorder,!1),t.prototype.init.call(this,i)},e.prototype.createData=function(t){var e=this,i=0,r=[],n=[];this.structure.eachPolymer(function(t){if(!(t.residueCount<4||t.isNucleic())){var o=new Ka(t),a=o.getAxis(e.localAngle,e.centerDist,e.ssBorder,e.getColorParams(),e.radius,e.scale);i+=a.size.length,r.push(a),n.push(o)}},t.getSelection());var o={begin:new Float32Array(3*i),end:new Float32Array(3*i),size:new Float32Array(i),color:new Float32Array(3*i),picking:new Float32Array(i)},a=0;return r.forEach(function(t){o.begin.set(t.begin,3*a),o.end.set(t.end,3*a),o.size.set(t.size,a),o.color.set(t.color,3*a),o.picking.set(t.picking.array,a),a+=t.size.length}),i&&(o.picking=new $m(o.picking,t.getStructure())),{bufferList:[new oy({position1:o.begin,position2:o.end,color:o.color,color2:o.color,radius:o.size,picking:o.picking},this.getBufferParams({openEnded:this.openEnded,radialSegments:this.radialSegments,disableImpostor:this.disableImpostor,dullInterior:!0}))],axisList:r,helixbundleList:n,axisData:o}},e.prototype.updateData=function(t,e){var i=this;if((t=t||{}).position)return void this.build();var r={};if(t.color||t.radius){var n=0;e.helixbundleList.forEach(function(r){var o=r.getAxis(i.localAngle,i.centerDist,i.ssBorder,i.getColorParams(),i.radius,i.scale);t.color&&e.axisData.color.set(o.color,3*n),(t.radius||t.scale)&&e.axisData.size.set(o.size,n),n+=o.size.length}),t.color&&(r.color=e.axisData.color,r.color2=e.axisData.color),(t.radius||t.scale)&&(r.radius=e.axisData.size)}e.bufferList[0].setAttributes(r)},e}(ky);df.add("rocket",px);var dx=function(t){function e(e,i,r){t.call(this,e,i,r),this.type="rope",this.parameters=Object.assign({smooth:{type:"integer",max:15,min:0,rebuild:!0}},this.parameters,{aspectRatio:null,smoothSheet:null})}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=e||{};i.aspectRatio=1,i.tension=dn(i.tension,.5),i.scale=dn(i.scale,5),i.smoothSheet=!1,this.smooth=dn(i.smooth,2),t.prototype.init.call(this,i)},e.prototype.getSpline=function(t){var e=new Za(t);return new ks(t,this.getSplineParams({directional:!1,positionIterator:e.getCenterIterator(this.smooth)}))},e}(Wb);df.add("rope",dx);var fx=function(t){function e(e,i,r){t.call(this,e,i,r),this.type="spacefill",this.parameters=Object.assign({sphereDetail:!0,disableImpostor:!0},this.parameters),this.init(r)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=e||{};t.prototype.init.call(this,i)},e.prototype.createData=function(t){return{bufferList:[new $v(t.getAtomData(this.getAtomParams()),this.getBufferParams({sphereDetail:this.sphereDetail,dullInterior:!0,disableImpostor:this.disableImpostor}))]}},e.prototype.updateData=function(t,e){var i=e.sview.getAtomData(this.getAtomParams(t)),r={};t&&!t.position||(r.position=i.position),t&&!t.color||(r.color=i.color),t&&!t.radius||(r.radius=i.radius),e.bufferList[0].setAttributes(r)},e}(ky);df.add("spacefill",fx);var mx=function(t){function e(e,i){var r=e||{},n=i||{},o=r.position.length/3-1,a=new Float32Array(3*o*2),s=new Float32Array(3*o*2);t.call(this,{position:a,color:s},n),this.setAttributes(e)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={isLine:{},vertexShader:{},fragmentShader:{}};return e.prototype.setAttributes=function(t){var e,i,r,n,o=this.geometry.attributes;if(t.position&&(e=t.position,r=o.position.array,o.position.needsUpdate=!0),t.color&&(i=t.color,n=o.color.array,o.color.needsUpdate=!0),!e&&!i)return void cf.warn("TraceBuffer.prototype.setAttributes no data");for(var a,s,c=this.size-1,u=0;u<c;++u)a=3*u,s=3*u*2,e&&(r[s]=e[a],r[s+1]=e[a+1],r[s+2]=e[a+2],r[s+3]=e[a+3],r[s+4]=e[a+4],r[s+5]=e[a+5]),i&&(n[s]=i[a],n[s+1]=i[a+1],n[s+2]=i[a+2],n[s+3]=i[a+3],n[s+4]=i[a+4],n[s+5]=i[a+5])},i.isLine.get=function(){return!0},i.vertexShader.get=function(){return"Line.vert"},i.fragmentShader.get=function(){return"Line.frag"},Object.defineProperties(e.prototype,i),e}(Lv),gx=function(t){function e(e,i,r){t.call(this,e,i,r),this.type="trace",this.parameters=Object.assign({subdiv:{type:"integer",max:50,min:1,rebuild:!0},tension:{type:"number",precision:1,max:1,min:.1},smoothSheet:{type:"boolean",rebuild:!0}},this.parameters,{flatShaded:null,side:null,wireframe:null}),this.init(r)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=e||{};i.colorScheme=dn(i.colorScheme,"chainname"),i.colorScale=dn(i.colorScale,"RdYlBu"),"low"===i.quality?this.subdiv=3:"medium"===i.quality?this.subdiv=6:"high"===i.quality?this.subdiv=12:this.subdiv=dn(i.subdiv,6),this.tension=dn(i.tension,NaN),this.smoothSheet=dn(i.smoothSheet,!1),t.prototype.init.call(this,i)},e.prototype.getSplineParams=function(t){return Object.assign({subdiv:this.subdiv,tension:this.tension,directional:!1,smoothSheet:this.smoothSheet},t)},e.prototype.createData=function(t){var e=this,i=[],r=[];return this.structure.eachPolymer(function(t){if(!(t.residueCount<4)){r.push(t);var n=new ks(t,e.getSplineParams()),o=n.getSubdividedPosition(),a=n.getSubdividedColor(e.getColorParams());i.push(new mx(Object.assign({},o,a),e.getBufferParams()))}},t.getSelection()),{bufferList:i,polymerList:r}},e.prototype.updateData=function(t,e){var i=this;t=t||{};var r=0,n=e.polymerList.length;for(r=0;r<n;++r){var o={},a=new ks(e.polymerList[r],i.getSplineParams());if(t.position){var s=a.getSubdividedPosition();o.position=s.position}if(t.color){var c=a.getSubdividedColor(i.getColorParams());o.color=c.color}e.bufferList[r].setAttributes(o)}},e.prototype.setParameters=function(e){var i={};return e&&e.tension&&(i.position=!0),t.prototype.setParameters.call(this,e,i,!1),this},e}(ky);df.add("trace",gx);var vx=function(t){function e(e,i,r){t.call(this,e,i,r),this.type="tube",this.parameters=Object.assign({},this.parameters,{aspectRatio:null})}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=e||{};i.aspectRatio=1,i.scale=dn(i.scale,2),"low"===i.quality&&(this.radialSegments=5),t.prototype.init.call(this,i)},e.prototype.getSplineParams=function(){return t.prototype.getSplineParams.call(this,{directional:!1})},e}(Wb);df.add("tube",vx);var yx=function(t){function e(e,i,r){t.call(this,e,i,r),this.type="unitcell",this.parameters=Object.assign({radius:{type:"number",precision:3,max:10,min:.001},sphereDetail:!0,radialSegments:!0,disableImpostor:!0},this.parameters,{assembly:null}),this.init(r)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=e||{},r=.5;this.structure.unitcell&&(r=Math.cbrt(this.structure.unitcell.volume)/200),i.radius=dn(i.radius,r),i.colorValue=dn(i.colorValue,"orange"),t.prototype.init.call(this,i)},e.prototype.getUnitcellData=function(t){return t.unitcell.getData(t)},e.prototype.create=function(){var t=this.structureView.getStructure();if(t.unitcell){var e=this.getUnitcellData(t);this.sphereBuffer=new $v(e.vertex,this.getBufferParams({sphereDetail:this.sphereDetail,disableImpostor:this.disableImpostor,dullInterior:!0})),this.cylinderBuffer=new oy(e.edge,this.getBufferParams({openEnded:!0,radialSegments:this.radialSegments,disableImpostor:this.disableImpostor,dullInterior:!0})),this.dataList.push({sview:this.structureView,bufferList:[this.sphereBuffer,this.cylinderBuffer]})}},e.prototype.updateData=function(t,e){var i=e.sview.getStructure(),r=this.getUnitcellData(i),n={},o={};t&&!t.position||(n.position=r.vertexPosition,o.position1=r.edgePosition1,o.position2=r.edgePosition2),t&&!t.color||(n.color=r.vertexColor,o.color=r.edgeColor,o.color2=r.edgeColor),t&&!t.radius||(n.radius=r.vertexRadius,o.radius=r.edgeRadius),this.sphereBuffer.setAttributes(n),this.cylinderBuffer.setAttributes(o)},e}(ky);df.add("unitcell",yx);var bx=function(t){function e(e,i,r){t.call(this,e,i,r),this.type="validation",this.parameters=Object.assign({},this.parameters,{radiusType:null,radius:null,scale:null}),this.init(r)}return t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e,e.prototype.init=function(e){var i=e||{};i.colorValue=dn(i.colorValue,"#f0027f"),t.prototype.init.call(this,i)},e.prototype.createData=function(t){if(t.validation){var e=t.validation.getClashData({structure:t,color:this.colorValue});return{bufferList:[new oy(e,this.getBufferParams({openEnded:!1}))]}}},e}(ky);df.add("validation",bx);var xx=function(t,e){var i=e||{};this.streamer=t,this.name=dn(i.name,""),this.path=dn(i.path,"")},_x={type:{},__objName:{}};_x.type.get=function(){return""},_x.__objName.get=function(){return""},xx.prototype.parse=function(){var t=this;return this.streamer.read().then(function(){return t._beforeParse(),t._parse(),t._afterParse(),t[t.__objName]})},xx.prototype._parse=function(){},xx.prototype._beforeParse=function(){},xx.prototype._afterParse=function(){t.Debug&&cf.log(this[this.__objName])},Object.defineProperties(xx.prototype,_x);var wx=function(t){function e(e,i){var r=i||{};t.call(this,e,r),this.firstModelOnly=dn(r.firstModelOnly,!1),this.asTrajectory=dn(r.asTrajectory,!1),this.cAlphaOnly=dn(r.cAlphaOnly,!1),this.structure=new Mv(this.name,this.path),this.structureBuilder=new $s(this.structure)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={type:{},__objName:{}};return i.type.get=function(){return"structure"},i.__objName.get=function(){return"structure"},Object.defineProperties(e.prototype,i),e}(xx),Sx=function(t,e,i,r,n){this.structure=t,this.index=e,this.description=i||"",this.entityType=Hs(r||""),this.chainIndexList=n||[],n.forEach(function(i){t.chainStore.entityIndex[i]=e})},Ax={type:{}};Ax.type.get=function(){return"Entity"},Sx.prototype.getEntityType=function(){return this.entityType},Sx.prototype.isPolymer=function(){return this.entityType===sg},Sx.prototype.isNonPolymer=function(){return this.entityType===cg},Sx.prototype.isMacrolide=function(){return this.entityType===ug},Sx.prototype.isWater=function(){return this.entityType===hg},Sx.prototype.eachChain=function(t){var e=this.structure.getChainProxy();this.chainIndexList.forEach(function(i){e.index=i,t(e)})},Object.defineProperties(Sx.prototype,Ax);var Mx=function(t){var e=t||{};this.a=e.a||1,this.b=e.b||1,this.c=e.c||1,this.alpha=e.alpha||90,this.beta=e.beta||90,this.gamma=e.gamma||90,this.spacegroup=e.spacegroup||"P 1",this.cartToFrac=e.cartToFrac||e.scale,this.fracToCart=new v;var i=Gn(this.alpha),r=Gn(this.beta),n=Gn(this.gamma),o=Math.cos(i),a=Math.cos(r),s=Math.cos(n),c=Math.sin(r),u=Math.sin(n);if(this.volume=this.a*this.b*this.c*Math.sqrt(1-o*o-a*a-s*s+2*o*a*s),void 0===this.cartToFrac){var h=this.a*this.b*u/this.volume,l=(a*s-o)/(c*u);this.fracToCart.set(this.a,0,0,0,this.b*s,this.b*u,0,0,this.c*a,-this.c*c*l,1/h,0,0,0,0,1).transpose(),this.cartToFrac=(new v).getInverse(this.fracToCart)}else this.fracToCart.getInverse(this.cartToFrac)};Mx.prototype.getPosition=function(t){function e(t,e,s){o.set(t,e,s).multiply(n).applyMatrix4(r.fracToCart).toArray(i,a),a+=3}var i=new Float32Array(24),r=t.unitcell,n=t.center.clone().applyMatrix4(r.cartToFrac).floor().multiplyScalar(2).addScalar(1),o=new g,a=0;return e(0,0,0),e(1,0,0),e(0,1,0),e(0,0,1),e(1,1,0),e(1,0,1),e(0,1,1),e(1,1,1),i},Mx.prototype.getCenter=function(t){return Eo(this.getPosition(t))},Mx.prototype.getData=function(t,e){function i(t,e){s.fromArray(c,3*t).toArray(l,m),s.fromArray(c,3*e).toArray(p,m),m+=3}var r=e||{},n=dn(r.colorValue,"orange"),o=dn(r.radius,Math.cbrt(this.volume)/200),a=new tt(n),s=new g,c=this.getPosition(t),u=To(8,a.r,a.g,a.b),h=Po(8,o),l=new Float32Array(36),p=new Float32Array(36),d=To(12,a.r,a.g,a.b),f=Po(12,o),m=0;i(0,1),i(0,2),i(0,3),i(1,4),i(1,5),i(2,6),i(3,5),i(4,7),i(5,7),i(2,4),i(7,6),i(3,6);var v=new ig(this,t);return{vertex:{position:c,color:u,radius:h,picking:v},edge:{position1:l,position2:p,color:d,color2:d,radius:f,picking:v}}};var Px={1:"h",2:"h",3:"i",4:"h",5:"g",6:"h",7:"h",8:"h",9:"h",10:"h","":"h"},Tx=function(e){function i(t,i){var r=i||{};e.call(this,t,r),this.hex=dn(r.hex,!1)}e&&(i.__proto__=e),i.prototype=Object.create(e&&e.prototype),i.prototype.constructor=i;var r={type:{}};return r.type.get=function(){return"pdb"},i.prototype._parse=function(){function e(t,e,r){for(var n=t;n<e;++n)if(l=r[n],"ATOM "===(p=l.substr(0,6))||"HETATM"===p){if(mt&&(X?(K?(a=new Float32Array(3*ht.count),Y.push(a)):a=[],s=0):W||(J={}),O=(R=1).toString(),D=!0,mt=!1),W&&ft>0)continue;var o=void 0,at=void 0,gt=void 0,vt=void 0,yt=void 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0;z?(d=parseInt(vt[1]),xt="",_="H"===l[0]?1:0,f=yt?"":vt[4],m=parseInt(vt[5-yt]),b="",g=vt[3],w=parseFloat(vt[9-yt]),S="",y=0):(d=parseInt(l.substr(6,5),$),V&&99999===d&&($=16),_="H"===l[0]?1:0,f=l[21].trim(),m=parseInt(l.substr(22,4),H)||1,V&&9999===m&&(H=16),b=l[26].trim(),g=l.substr(17,4).trim()||"MOL",w=parseFloat(l.substr(60,6)),S=l[16].trim(),y=parseFloat(l.substr(54,6)),i||(xt=l.substr(76,2).trim(),f||(f=l.substr(72,4).trim()))),ht.growIfFull(),ht.atomTypeId[dt]=ut.add(x,xt),ht.x[dt]=o,ht.y[dt]=at,ht.z[dt]=gt,ht.serial[dt]=d,ht.bfactor[dt]=isNaN(w)?0:w,ht.altloc[dt]=S.charCodeAt(0),ht.occupancy[dt]=isNaN(y)?0:y,_?N===f&&B===g&&(Ig.includes(g)||k===m&&F===b)||(O=(R+=1).toString(),k=m,B=g,F=b):D||N===f||(O=(R+=1).toString()),G.addAtom(ft,f,O,g,m,_,void 0,b),J[d]=dt,dt+=1,D=!1,N=f}else if("CONECT"===p){var _t=J[parseInt(l.substr(6,5))],wt=[11,16,21,26],St={};if(void 0===_t)continue;for(var At=0;At<4;++At){var Mt=parseInt(l.substr(wt[At],5));if(!Number.isNaN(Mt)&&void 0!==(Mt=J[Mt]))if(_t<Mt?(lt.index=_t,pt.index=Mt):(lt.index=Mt,pt.index=_t),void 0!==St[Mt])j.bondStore.bondOrder[St[Mt]]+=1;else{var Pt=lt.index+"|"+pt.index;void 0===et[Pt]&&(et[Pt]=!0,St[Mt]=j.bondStore.count,j.bondStore.addBond(lt,pt,1))}}}else if("HELIX "===p){A=l[19].trim(),M=parseInt(l.substr(21,4)),P=l[25].trim(),T=l[31].trim(),E=parseInt(l.substr(33,4)),C=l[37].trim();var Tt=parseInt(l.substr(39,1));Tt=(Px[Tt]||Px[""]).charCodeAt(0),st.push([A,M,P,T,E,C,Tt])}else if("SHEET "===p)A=l[21].trim(),M=parseInt(l.substr(22,4)),P=l[26].trim(),T=l[32].trim(),E=parseInt(l.substr(33,4)),C=l[37].trim(),ct.push([A,M,P,T,E,C]);else if("HETNAM"===p)ot[l.substr(11,3)]=l.substr(15).trim();else if("COMPND"===p){var Et=l.substr(10,70).trim(),Ct=Et.indexOf(":"),It=Et.substring(0,Ct),Lt=void 0;rt.includes(It)?(L=It,Lt=Et.substring(Ct+2)):Lt=Et,Lt=Lt.replace(/;$/,""),"MOL_ID"===L?(I={chainList:[],name:""},it.push(I)):"MOLECULE"===L?(I.name&&(I.name+=" 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":"")+l.substr(10,70).trim();else if("MODEL "===p)mt=!0;else if("ENDMDL"===p||l.startsWith("END")){if(mt)continue;X&&!K&&(Y.push(new Float32Array(a)),K=!0),ft+=1,mt=!0}else if("MTRIX"===l.substr(0,5)){if("1"===l[59])continue;var jt=l.split(/\s+/),Gt=jt[1].trim();if("1"===l[5]&&"1"===Gt){c=new iv("NCS"),Q.NCS=c,u=c.addPart()}var Vt=parseInt(l[5])-1;0===Vt&&(h=new v,u.matrixList.push(h));var $t=h.elements;$t[0+Vt]=parseFloat(jt[2]),$t[4+Vt]=parseFloat(jt[3]),$t[8+Vt]=parseFloat(jt[4]),$t[12+Vt]=parseFloat(jt[5])}else if("ORIGX"===l.substr(0,5)){tt.origx||(tt.origx=new v);var Ht=l.split(/\s+/),Wt=parseInt(l[5])-1,Xt=tt.origx.elements;Xt[0+Wt]=parseFloat(Ht[1]),Xt[4+Wt]=parseFloat(Ht[2]),Xt[8+Wt]=parseFloat(Ht[3]),Xt[12+Wt]=parseFloat(Ht[4])}else if("SCALE"===l.substr(0,5)){tt.scale||(tt.scale=new v);var qt=l.split(/\s+/),Yt=parseInt(l[5])-1,Zt=tt.scale.elements;Zt[0+Yt]=parseFloat(qt[1]),Zt[4+Yt]=parseFloat(qt[2]),Zt[8+Yt]=parseFloat(qt[3]),Zt[12+Yt]=parseFloat(qt[4])}else if("CRYST1"===p){var Kt=parseFloat(l.substr(6,9)),Qt=parseFloat(l.substr(15,9)),Jt=parseFloat(l.substr(24,9)),te=parseFloat(l.substr(33,7)),ee=parseFloat(l.substr(40,7)),ie=parseFloat(l.substr(47,7)),re=l.substr(55,11).trim(),ne=new Float32Array(9);ne[0]=Kt,ne[4]=Qt,ne[8]=Jt,Z.push(ne),0===ft&&(tt.a=Kt,tt.b=Qt,tt.c=Jt,tt.alpha=te,tt.beta=ee,tt.gamma=ie,tt.spacegroup=re)}}t.Debug&&cf.time("PdbParser._parse "+this.name);var i=!1,r=this.streamer.peekLines(1)[0],n=r.substr(62,4),o=r.substr(72,4);n===o&&o.trim()&&(i=!0);var a,s,c,u,h,l,p,d,f,m,g,y,b,x,_,w,S,A,M,P,T,E,C,I,L,R,O,D,N,k,B,F,z="pqr"===this.type,U=/\s+/,j=this.structure,G=this.structureBuilder,V=this.hex,$=10,H=10,W=this.firstModelOnly,X=this.asTrajectory,q=this.cAlphaOnly,Y=j.frames,Z=j.boxes,K=!1,Q=j.biomolDict,J={},tt={},et={},it=[],rt=["MOL_ID","MOLECULE","CHAIN","FRAGMENT","SYNONYM","EC","ENGINEERED","MUTATION","OTHER_DETAILS"],nt={},ot={},at={helices:[],sheets:[]},st=at.helices,ct=at.sheets,ut=j.atomMap,ht=j.atomStore;ht.resize(Math.round(this.streamer.data.length/80));var lt=j.getAtomProxy(),pt=j.getAtomProxy(),dt=0,ft=0,mt=!0;this.streamer.eachChunkOfLines(function(t){e(0,t.length,t)});var gt=it.length;if(it.length){j.eachChain(function(t){t.entityIndex=gt}),it.forEach(function(t,e){var i=t.chainList.map(function(t){return nt[t]});j.entityList.push(new Sx(j,e,t.name,"polymer",i))});var vt=it.length,yt=j.getResidueProxy(),bt={};j.eachChain(function(t){t.entityIndex===gt&&(yt.index=t.residueOffset,bt[yt.resname]||(bt[yt.resname]=[]),bt[yt.resname].push(t.index))}),Object.keys(bt).forEach(function(t){var e=bt[t],i="non-polymer",r=ot[t]||t;Ig.includes(t)&&(r="water",i="water"),j.entityList.push(new Sx(j,vt,r,i,e)),vt+=1})}void 0!==tt.a?j.unitcell=new Mx(tt):j.unitcell=void 0,(st.length||ct.length)&&rs(j,at),G.finalize(),j.finalizeAtoms(),i||ns(j),os(j),j.finalizeBonds(),st.length||ct.length||av(j),hs(j),t.Debug&&cf.timeEnd("PdbParser._parse "+this.name)},Object.defineProperties(i.prototype,r),i}(wx);ff.add("pdb",Tx),ff.add("pdb1",Tx),ff.add("ent",Tx);var Ex=/\s+/,Cx=/'((?:(?!'\s).)*)'|"((?:(?!"\s).)*)"|(\S+)/g,Ix=/"/g,Lx=/^['"]+|['"]+$/g,Rx=function(e){function i(){e.apply(this,arguments)}e&&(i.__proto__=e),i.prototype=Object.create(e&&e.prototype),i.prototype.constructor=i;var r={type:{}};return r.type.get=function(){return"cif"},i.prototype._parse=function(){function 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rt=o.split(Ex);j&&(a=G.indexOf("auth_asym_id"),s=G.indexOf("auth_seq_id"),c=G.indexOf("label_atom_id"),u=G.indexOf("label_comp_id"),h=G.indexOf("label_asym_id"),l=G.indexOf("label_entity_id"),p=G.indexOf("label_alt_id"),y=G.indexOf("Cartn_x"),b=G.indexOf("Cartn_y"),x=G.indexOf("Cartn_z"),f=G.indexOf("id"),m=G.indexOf("type_symbol"),d=G.indexOf("group_PDB"),_=G.indexOf("B_iso_or_equiv"),g=G.indexOf("pdbx_PDB_model_num"),v=G.indexOf("pdbx_PDB_ins_code"),w=G.indexOf("occupancy"),j=!1,H=parseInt(rt[g]),P&&(i=[],r=0));var nt=parseInt(rt[g]);if(H!==nt&&(P&&(0===X&&E.push(new Float32Array(i)),i=new Float32Array(3*$.count),E.push(i),r=0),X+=1),H=nt,M&&X>0)continue;var ot=rt[c].replace(Ix,"");if(T&&"CA"!==ot)continue;var at=parseFloat(rt[y]),st=parseFloat(rt[b]),ct=parseFloat(rt[x]);if(P){var ut=3*r;if(i[ut+0]=at,i[ut+1]=st,i[ut+2]=ct,r+=1,X>0)continue}var ht=rt[u],lt=parseInt(rt[s]),pt=rt[v];pt="?"===pt?"":pt;var dt=rt[a],ft=rt[h],mt="H"===rt[d][0]?1:0,gt=rt[m],vt=parseFloat(rt[_]),yt=parseFloat(rt[w]),bt=rt[p];if(bt="."===bt?"":bt,$.growIfFull(),$.atomTypeId[W]=V.add(ot,gt),$.x[W]=at,$.y[W]=st,$.z[W]=ct,$.serial[W]=parseInt(rt[f]),$.bfactor[W]=isNaN(vt)?0:vt,$.occupancy[W]=isNaN(yt)?0:yt,$.altloc[W]=bt.charCodeAt(0),A.addAtom(X,dt,ft,ht,lt,mt,void 0,pt),t.Debug){var xt=I[ft];void 0!==xt&&xt!==dt&&t.Debug&&cf.warn(xt,dt)}I[ft]=dt;var _t=rt[l];L[_t]||(L[_t]=new Set),L[_t].add(S.chainStore.count-1),W+=1}else{var wt=o.match(Cx),St=wt.length;F===B.length&&(F=0);for(var At=0;At<St;++At)B[F+At].push(wt[At]);F+=St}k=!1}else if("'"===o[0]&&"'"===o[o.length-1]){var Mt=o.substring(1,o.length-1);!1===U?C[z]=Mt:C[z][U]=Mt}else D?!1===U?C[z]=o:C[z][U]=o:t.Debug&&cf.log("CifParser._parse: unknown state",o);else R=!1,N=!1,D=!1,B.length=0,F=null,z=null,U=null,j=null,G.length=0}cf.time("CifParser._parse "+this.name);var i,r,n,o,a,s,c,u,h,l,p,d,f,m,g,v,y,b,x,_,w,S=this.structure,A=this.structureBuilder,M=this.firstModelOnly,P=this.asTrajectory,T=this.cAlphaOnly,E=S.frames,C={},I={},L={},R=!1,O=null,D=!1,N=!1,k=!1,B=[],F=null,z=null,U=null,j=null,G=[],V=S.atomMap,$=S.atomStore;$.resize(this.streamer.data.length/100);var H,W=0,X=0;if(this.streamer.eachChunkOfLines(function(t){e(0,t.length,t)}),C.chem_comp&&C.chem_comp_atom)Ks(C,S,A),A.finalize(),S.finalizeAtoms(),S.finalizeBonds(),ps(S);else if(C.atom_site_type_symbol&&C.atom_site_label&&C.atom_site_fract_x)Qs(C,S,A),A.finalize(),S.finalizeAtoms(),os(S),S.finalizeBonds();else{var q=Js(C,S,I);if(tc(C,S,I),ec(C,S,I),ic(C,S,L),C.struct&&C.struct.title&&(S.title=C.struct.title.trim().replace(Lx,"")),C.entry&&C.entry.id&&(S.id=C.entry.id.trim().replace(Lx,"")),C.database_PDB_rev){if(C.database_PDB_rev.date){Xs(C.database_PDB_rev,"date");var Y=C.database_PDB_rev.date.filter(qs);Y.length&&(S.header.releaseDate=Y[Y.length-1])}if(C.database_PDB_rev.date_original){Xs(C.database_PDB_rev,"date_original");var Z=C.database_PDB_rev.date_original.filter(qs);Z.length&&(S.header.depositionDate=Z[Z.length-1])}}C.reflns&&C.reflns.d_resolution_high?qs(C.reflns.d_resolution_high)&&(S.header.resolution=parseFloat(C.reflns.d_resolution_high)):C.refine&&C.refine.ls_d_res_high&&qs(C.refine.ls_d_res_high)&&(S.header.resolution=parseFloat(C.refine.ls_d_res_high)),C.refine&&C.refine.ls_R_factor_R_free&&qs(C.refine.ls_R_factor_R_free)&&(S.header.rFree=parseFloat(C.refine.ls_R_factor_R_free)),C.refine&&C.refine.ls_R_factor_R_work&&qs(C.refine.ls_R_factor_R_work)&&(S.header.rWork=parseFloat(C.refine.ls_R_factor_R_work)),C.exptl&&C.exptl.method&&(Xs(C.exptl,"method"),S.header.experimentalMethods=C.exptl.method.map(function(t){return t.replace(Lx,"")})),A.finalize(),S.finalizeAtoms(),os(S),S.finalizeBonds(),q?rs(S,q):av(S),hs(S),S.extraData.cif=C}t.Debug&&cf.timeEnd("CifParser._parse "+this.name)},Object.defineProperties(i.prototype,r),i}(wx);ff.add("cif",Rx),ff.add("mcif",Rx),ff.add("mmcif",Rx);var Ox=function(e){function i(){e.apply(this,arguments)}e&&(i.__proto__=e),i.prototype=Object.create(e&&e.prototype),i.prototype.constructor=i;var r={type:{}};return r.type.get=function(){return"gro"},i.prototype._parse=function(){function e(t,e,n){for(var l=t;l<e;++l){var T=++P-1,E=n[l];if(E)if(T%_==0)s&&(i=new Float32Array(3*x),u.push(i),r=0);else if(T%_==1);else if(T%_==_-1){var C=E.trim().split(/\s+/),I=new Float32Array(9);if(I[0]=10*parseFloat(C[0]),I[4]=10*parseFloat(C[1]),I[8]=10*parseFloat(C[2]),h.push(I),a)return!0;M+=1}else{if(p=E.substr(10,5).trim(),c&&"CA"!==p)continue;var L=10*parseFloat(E.substr(v,g)),R=10*parseFloat(E.substr(y,g)),O=10*parseFloat(E.substr(b,g));if(s){var D=3*r;if(i[D+0]=L,i[D+1]=R,i[D+2]=O,r+=1,T>_)continue}d=E.substr(5,5).trim(),f=parseInt(E.substr(0,5)),m=parseInt(E.substr(15,5)),S.growIfFull(),S.atomTypeId[A]=w.add(p),S.x[A]=L,S.y[A]=R,S.z[A]=O,S.serial[A]=m,o.addAtom(M,"","",d,f,0,"l"),A+=1}}}t.Debug&&cf.time("GroParser._parse "+this.name);var i,r,n=this.structure,o=this.structureBuilder,a=this.firstModelOnly,s=this.asTrajectory,c=this.cAlphaOnly,u=n.frames,h=n.boxes,l=this.streamer.peekLines(3);n.title=l[0].trim();var p,d,f,m,g=5+(l[2].length-l[2].lastIndexOf(".")-1),v=20,y=20+g,b=20+2*g,x=parseInt(l[1]),_=x+3,w=n.atomMap,S=n.atomStore;S.resize(x);var A=0,M=0,P=0;this.streamer.eachChunkOfLines(function(t){e(0,t.length,t)}),o.finalize(),n.finalizeAtoms(),ns(n),os(n),n.finalizeBonds(),av(n),t.Debug&&cf.timeEnd("GroParser._parse "+this.name)},Object.defineProperties(i.prototype,r),i}(wx);ff.add("gro",Ox);var Dx=["xCoordList","yCoordList","zCoordList","groupIdList","groupTypeList","chainIdList","bFactorList","atomIdList","altLocList","occupancyList","secStructList","insCodeList","sequenceIndexList","chainNameList","bondAtomList","bondOrderList"],Nx=["mmtfVersion","mmtfProducer","unitCell","spaceGroup","structureId","title","depositionDate","releaseDate","experimentalMethods","resolution","rFree","rWork","bioAssemblyList","ncsOperatorList","entityList","groupList","numBonds","numAtoms","numGroups","numChains","numModels","groupsPerChain","chainsPerModel"].concat(Dx),kx={0:"i".charCodeAt(0),1:"s".charCodeAt(0),2:"h".charCodeAt(0),3:"e".charCodeAt(0),4:"g".charCodeAt(0),5:"b".charCodeAt(0),6:"t".charCodeAt(0),7:"l".charCodeAt(0),"-1":"".charCodeAt(0)},Bx=function(e){function i(){e.apply(this,arguments)}e&&(i.__proto__=e),i.prototype=Object.create(e&&e.prototype),i.prototype.constructor=i;var r={type:{}};return r.type.get=function(){return"mmtf"},i.prototype._parse=function(){t.Debug&&cf.time("MmtfParser._parse "+this.name);var e,i,r,n,o,a=this.structure,s=Ac(wc(this.streamer.data));["depositionDate","releaseDate","resolution","rFree","rWork","experimentalMethods"].forEach(function(t){void 0!==s[t]&&(a.header[t]=s[t])});var c,u,h,l,p,d;if(a.id=s.structureId,a.title=s.title,this.firstModelOnly||this.asTrajectory){for(p=1,h=0,e=0,i=l=s.chainsPerModel[0];e<i;++e)h+=s.groupsPerChain[e];for(u=0,e=0,i=h;e<i;++e)u+=(o=s.groupList[s.groupTypeList[e]]).atomNameList.length;c=s.numBonds,d=[l]}else c=s.numBonds,u=s.numAtoms,h=s.numGroups,l=s.numChains,p=s.numModels,d=s.chainsPerModel;if(c+=h,this.asTrajectory)for(e=0,i=s.numModels;e<i;++e){var f=new Float32Array(3*u),m=u*e;for(r=0;r<u;++r){var g=3*r,y=r+m;f[g]=s.xCoordList[y],f[g+1]=s.yCoordList[y],f[g+2]=s.zCoordList[y]}a.frames.push(f)}var b=new Uint32Array(c),x=new Uint32Array(c),_=new Uint8Array(c),w=new Uint32Array(u),S=new Uint32Array(h),A=new Uint32Array(h),M=new Uint16Array(h),P=new Uint16Array(l),T=new Uint32Array(l),E=new Uint32Array(l),C=new Uint32Array(p),I=new Uint32Array(p),L=0;for(e=0,i=p;e<i;++e){var R=d[e];for(C[e]=L,I[e]=R,r=0;r<R;++r)P[r+L]=e;L+=R}var O=s.groupsPerChain,D=0;for(e=0,i=l;e<i;++e){var N=O[e];for(T[e]=D,E[e]=N,r=0;r<N;++r)S[r+D]=e;D+=N}var k=0,B=0;for(e=0,i=h;e<i;++e){var F=(o=s.groupList[s.groupTypeList[e]]).atomNameList.length,z=o.bondAtomList,U=o.bondOrderList;for(r=0,n=U.length;r<n;++r)b[B]=k+z[2*r],x[B]=k+z[2*r+1],_[B]=U[r],B+=1;for(A[e]=k,M[e]=F,r=0;r<F;++r)w[k]=e,k+=1}var j=s.bondAtomList;if(j)for(s.bondOrderList&&_.set(s.bondOrderList,B),e=0,i=j.length;e<i;e+=2){var G=j[e],V=j[e+1];G<u&&V<u&&(b[B]=G,x[B]=V,B+=1)}a.bondStore.length=_.length,a.bondStore.count=B,a.bondStore.atomIndex1=b,a.bondStore.atomIndex2=x,a.bondStore.bondOrder=_,a.atomStore.length=u,a.atomStore.count=u,a.atomStore.residueIndex=w,a.atomStore.atomTypeId=new Uint16Array(u),a.atomStore.x=s.xCoordList.subarray(0,u),a.atomStore.y=s.yCoordList.subarray(0,u),a.atomStore.z=s.zCoordList.subarray(0,u),a.atomStore.serial=s.atomIdList.subarray(0,u),a.atomStore.bfactor=s.bFactorList.subarray(0,u),a.atomStore.altloc=s.altLocList.subarray(0,u),a.atomStore.occupancy=s.occupancyList.subarray(0,u),a.residueStore.length=h,a.residueStore.count=h,a.residueStore.chainIndex=S,a.residueStore.residueTypeId=s.groupTypeList,a.residueStore.atomOffset=A,a.residueStore.atomCount=M,a.residueStore.resno=s.groupIdList.subarray(0,h),a.residueStore.sstruc=s.secStructList.subarray(0,h),a.residueStore.inscode=s.insCodeList.subarray(0,h),a.chainStore.length=l,a.chainStore.count=l,a.chainStore.entityIndex=new Uint16Array(l),a.chainStore.modelIndex=P,a.chainStore.residueOffset=T,a.chainStore.residueCount=E,a.chainStore.chainname=s.chainNameList.subarray(0,4*l),a.chainStore.chainid=s.chainIdList.subarray(0,4*l),a.modelStore.length=p,a.modelStore.count=p,a.modelStore.chainOffset=C,a.modelStore.chainCount=I;var $={};for(e=0,i=s.groupList.length;e<i;++e){var H=s.groupList[e],W=[];for(r=0,n=H.atomNameList.length;r<n;++r){var X=H.elementList[r].toUpperCase(),q=H.atomNameList[r];W.push(a.atomMap.add(q,X))}var Y=H.chemCompType.toUpperCase(),Z=vg.includes(Y),K=H.bondOrderList.length,Q=new Array(K),J=new Array(K);for(r=0;r<K;++r)Q[r]=H.bondAtomList[2*r],J[r]=H.bondAtomList[2*r+1];var tt={atomIndices1:Q,atomIndices2:J,bondOrders:H.bondOrderList};$[e]=a.residueMap.add(H.groupName,W,Z,Y,tt)}for(e=0,i=h;e<i;++e)a.residueStore.residueTypeId[e]=$[a.residueStore.residueTypeId[e]];for(e=0,i=a.atomStore.count;e<i;++e){var et=a.atomStore.residueIndex[e],it=a.residueMap.list[a.residueStore.residueTypeId[et]],rt=a.residueStore.atomOffset[et];a.atomStore.atomTypeId[e]=it.atomTypeIdList[e-rt]}if(s.secStructList){var nt=s.secStructList.length;for(e=0,i=a.residueStore.count;e<i;++e){var ot=kx[a.residueStore.sstruc[e%nt]];void 0!==ot&&(a.residueStore.sstruc[e]=ot)}}if(s.entityList&&s.entityList.forEach(function(t,e){a.entityList[e]=new Sx(a,e,t.description,t.type,t.chainIndexList)}),s.bioAssemblyList&&s.bioAssemblyList.forEach(function(t,e){var i=e+1,r=new iv(i);a.biomolDict["BU"+i]=r;var n={};t.transformList.forEach(function(t){var e=(new v).fromArray(t.matrix).transpose(),i=t.chainIndexList.map(function(t){for(var e="",i=0;i<4;++i){var r=s.chainNameList[4*t+i];if(!r)break;e+=String.fromCharCode(r)}return e}),o=n[i];o?o.matrixList.push(e):n[i]=r.addPart([e],i)})}),s.ncsOperatorList){var at=new iv("NCS"),st=at.addPart();s.ncsOperatorList.forEach(function(t){var e=(new v).fromArray(t).transpose();st.matrixList.push(e)}),st.matrixList.length>0&&(a.biomolDict.NCS=at)}var ct=s.unitCell;ct&&Array.isArray(ct)&&ct[0]?a.unitcell=new Mx({a:ct[0],b:ct[1],c:ct[2],alpha:ct[3],beta:ct[4],gamma:ct[5],spacegroup:s.spaceGroup}):a.unitcell=void 0,us(a,!0),cs(a,!0),a.finalizeAtoms(),a.finalizeBonds(),hs(a),t.Debug&&cf.timeEnd("MmtfParser._parse "+this.name)},Object.defineProperties(i.prototype,r),i}(wx);ff.add("mmtf",Bx);var Fx=/\s+/,zx=function(e){function i(){e.apply(this,arguments)}e&&(i.__proto__=e),i.prototype=Object.create(e&&e.prototype),i.prototype.constructor=i;var r={type:{}};return r.type.get=function(){return"mol2"},i.prototype._parse=function(){function e(t,e,A){for(var M,P=t;P<e;++P){var T=A[P].trim();if(""!==T&&"#"!==T[0])if("@"===T[0])"@<TRIPOS>MOLECULE"===T?(v=y,d=0,++m):"@<TRIPOS>ATOM"===T?(v=b,f=l.count,s&&(r=0,i=new Float32Array(3*g),c.push(i),m>0&&(u=!0))):v="@<TRIPOS>BOND"===T?x:0;else if(v===y)0===d?(n.title=T,n.id=T):1===d&&(M=T.split(Fx),g=parseInt(M[0])),++d;else if(v===b){if(M=T.split(Fx),a&&m>0)continue;var E=parseFloat(M[2]),C=parseFloat(M[3]),I=parseFloat(M[4]);if(s){var L=3*r;if(i[L+0]=E,i[L+1]=C,i[L+2]=I,r+=1,u)continue}var R=M[0],O=M[1],D=M[5].split(".")[0],N=M[6]?parseInt(M[6]):1,k=M[7]?M[7]:"",B=M[8]?parseFloat(M[8]):0;l.growIfFull(),l.atomTypeId[p]=h.add(O,D),l.x[p]=E,l.y[p]=C,l.z[p]=I,l.serial[p]=R,l.bfactor[p]=B,o.addAtom(m,"","",k,N,1),p+=1}else if(v===x){if(a&&m>0)continue;if(s&&m>0)continue;M=T.split(Fx),_.index=parseInt(M[1])-1+f,w.index=parseInt(M[2])-1+f;var F=S[M[3]];n.bondStore.addBond(_,w,F)}}}t.Debug&&cf.time("Mol2Parser._parse "+this.name);var i,r,n=this.structure,o=this.structureBuilder,a=this.firstModelOnly,s=this.asTrajectory,c=n.frames,u=!1,h=n.atomMap,l=n.atomStore;l.resize(Math.round(this.streamer.data.length/60));var p=0,d=0,f=0,m=-1,g=0,v=0,y=1,b=2,x=3,_=n.getAtomProxy(),w=n.getAtomProxy(),S={1:1,2:2,3:3,am:1,ar:1,du:1,un:1,nc:0};this.streamer.eachChunkOfLines(function(t){e(0,t.length,t)}),o.finalize(),n.finalizeAtoms(),ns(n),cs(n,!0),us(n,!0),n.finalizeBonds(),ps(n),av(n),t.Debug&&cf.timeEnd("Mol2Parser._parse "+this.name)},Object.defineProperties(i.prototype,r),i}(wx);ff.add("mol2",zx);var Ux=function(t){function e(){t.apply(this,arguments)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={type:{}};return i.type.get=function(){return"pqr"},Object.defineProperties(e.prototype,i),e}(Tx);ff.add("pqr",Ux);var jx=1,Gx=2,Vx=3,$x=4,Hx=5,Wx=6,Xx=/\s+/,qx=/(^\*|REMARK)*/,Yx=function(e){function i(){e.apply(this,arguments)}e&&(i.__proto__=e),i.prototype=Object.create(e&&e.prototype),i.prototype.constructor=i;var r={type:{}};return r.type.get=function(){return"psf"},i.prototype._parse=function(){function e(t,e,a){for(var d=t;d<e;++d){var f=a[d].trim();if(f)if(i===Gx){var m=f.split(Xx),g=parseInt(m[0]),v=parseInt(m[2]),y=m[3],b=m[4];u.growIfFull(),u.atomTypeId[l]=c.add(b),u.serial[l]=g,s.addAtom(0,"","",y,v,1),l+=1}else if(i===Vx)for(var x=f.split(Xx),_=0,w=x.length;_<w;_+=2)r[p]=parseInt(x[_])-1,n[p]=parseInt(x[_+1])-1,o[p]=1,p+=1;else if(i===jx)h.push(f.replace(qx,"").trim());else if(i===$x);else if(i===Hx);else if(i===Wx);else if(f.includes("!NATOM")){i=Gx;var S=parseInt(f.split(Xx)[0]);u.resize(S)}else if(f.includes("!NBOND")){i=Vx;var A=parseInt(f.split(Xx)[0]);r=new Uint32Array(A),n=new Uint32Array(A),o=new Uint8Array(A)}else f.includes("!NTITLE")?i=jx:f.includes("!NTHETA")?i=$x:f.includes("!NPHI")?i=Hx:f.includes("!NIMPHI")&&(i=Wx);else i=void 0}}t.Debug&&cf.time("PsfParser._parse "+this.name);var i,r,n,o,a=this.structure,s=this.structureBuilder,c=a.atomMap,u=a.atomStore,h=[],l=0,p=0;this.streamer.eachChunkOfLines(function(t){e(0,t.length,t)}),a.title=h.join(" "),a.bondStore.length=o.length,a.bondStore.count=p,a.bondStore.atomIndex1=r,a.bondStore.atomIndex2=n,a.bondStore.bondOrder=o,s.finalize(),a.finalizeAtoms(),ns(a),a.finalizeBonds(),ps(a),t.Debug&&cf.timeEnd("PsfParser._parse "+this.name)},Object.defineProperties(i.prototype,r),i}(wx);ff.add("psf",Yx);var Zx=/> <(.+)>/,Kx=function(e){function i(){e.apply(this,arguments)}e&&(i.__proto__=e),i.prototype=Object.create(e&&e.prototype),i.prototype.constructor=i;var r={type:{}};return r.type.get=function(){return"sdf"},i.prototype._parse=function(){function e(t,e,a){for(var C=t;C<e;++C){var I=a[C];if("$$$$"===I.substr(0,4))v=-1,++y,b=p.count,x.push(w),w={},_=!1;else if(3===v)S=parseInt(I.substr(0,3)),A=parseInt(I.substr(3,3)),E=(T=P=(M=4)+S)+A,o&&(c=0,s=new Float32Array(3*S),u.push(s),y>0&&(h=!0));else if(v>=M&&v<P){if(n&&y>0)continue;var L=parseFloat(I.substr(0,10)),R=parseFloat(I.substr(10,10)),O=parseFloat(I.substr(20,10));if(o){var D=3*c;if(s[D+0]=L,s[D+1]=R,s[D+2]=O,c+=1,h)continue}var N=I.substr(31,3).trim(),k=N+(g+1);p.growIfFull(),p.atomTypeId[g]=l.add(k,N),p.x[g]=L,p.y[g]=R,p.z[g]=O,p.serial[g]=g,r.addAtom(y,"","","HET",1,1),g+=1}else if(v>=T&&v<E){if(n&&y>0)continue;if(o&&y>0)continue;f.index=parseInt(I.substr(0,3))-1+b,m.index=parseInt(I.substr(3,3))-1+b;var B=parseInt(I.substr(6,3));i.bondStore.addBond(f,m,B)}else(d=I.match(Zx))?(_=d[1],w[_]=[]):!1!==_&&I&&w[_].push(I);++v}}t.Debug&&cf.time("SdfParser._parse "+this.name);var i=this.structure,r=this.structureBuilder,n=this.firstModelOnly,o=this.asTrajectory,a=this.streamer.peekLines(2);i.id=a[0].trim(),i.title=a[1].trim();var s,c,u=i.frames,h=!1,l=i.atomMap,p=i.atomStore;p.resize(Math.round(this.streamer.data.length/50));var d,f=i.getAtomProxy(),m=i.getAtomProxy(),g=0,v=0,y=0,b=0,x=[],_=!1,w={};i.extraData.sdf=x;var S,A,M,P,T,E;this.streamer.eachChunkOfLines(function(t){e(0,t.length,t)}),r.finalize(),i.finalizeAtoms(),i.finalizeBonds(),ps(i),t.Debug&&cf.timeEnd("SdfParser._parse "+this.name)},i.prototype._postProcess=function(){ps(this.structure)},Object.defineProperties(i.prototype,r),i}(wx);ff.add("sdf",Kx),ff.add("sd",Kx);var Qx=function(t,e){this.name=t,this.path=e,this.coordinates=[],this.boxes=[]},Jx={type:{}};Jx.type.get=function(){return"Frames"},Object.defineProperties(Qx.prototype,Jx);var t_=function(e){function i(){e.apply(this,arguments)}e&&(i.__proto__=e),i.prototype=Object.create(e&&e.prototype),i.prototype.constructor=i;var r={type:{}};return r.type.get=function(){return"dcd"},i.prototype._parse=function(){t.Debug&&cf.time("DcdParser._parse "+this.name);var e=this.streamer.data;e instanceof Uint8Array&&(e=e.buffer);var i,r,n=new DataView(e),o=this.frames,a=o.coordinates,s=o.boxes,c={},u=0,h=new Int32Array(e,0,23),l=h[0]!==n.getInt32(0);if(84!==h[0])for(r=e.byteLength,i=0;i<r;i+=4)n.setFloat32(i,n.getFloat32(i),!0);84!==h[0]&&cf.error("dcd bad format, header block start"),"CORD"!==String.fromCharCode(n.getUint8(4),n.getUint8(5),n.getUint8(6),n.getUint8(7))&&cf.error("dcd bad format, format string");var p=!1,d=!1,f=!1;0!==h[22]&&(p=!0,0!==h[12]&&(d=!0),1===h[13]&&(f=!0)),c.NSET=h[2],c.ISTART=h[3],c.NSAVC=h[4],c.NAMNF=h[10],c.DELTA=p?n.getFloat32(44,l):n.getFloat64(44,l),84!==h[22]&&cf.error("dcd bad format, header block end"),u=u+84+8;var m=n.getInt32(u,l),g=u+1;if((m-4)%80!=0&&cf.error("dcd bad format, title block start"),c.TITLE=Pn(new Uint8Array(e,g,m)),n.getInt32(g+m+4-1,l)!==m&&cf.error("dcd bad format, title block end"),u=u+m+8,4!==n.getInt32(u,l)&&cf.error("dcd bad format, natom block start"),c.NATOM=n.getInt32(u+4,l),4!==n.getInt32(u+8,l)&&cf.error("dcd bad format, natom block end"),u=u+4+8,c.NAMNF>0)return void cf.error("dcd format with fixed atoms unsupported, aborting");var v=c.NATOM,y=4*v;for(i=0,r=c.NSET;i<r;++i){if(d){u+=4;var b=new Float32Array(9);b[0]=n.getFloat64(u,l),b[4]=n.getFloat64(u+16,l),b[8]=n.getFloat64(u+40,l),s.push(b),u+=48,u+=4}for(var x=new Float32Array(3*v),_=0;_<3;++_){n.getInt32(u,l)!==y&&cf.error("dcd bad format, coord block start",i,_),u+=4;for(var w=new Float32Array(e,u,v),S=0;S<v;++S)x[3*S+_]=w[S];u+=y,n.getInt32(u,l)!==y&&cf.error("dcd bad format, coord block end",i,_),u+=4}a.push(x),f&&(u+=4+n.getInt32(u,l)+4)}t.Debug&&cf.timeEnd("DcdParser._parse "+this.name)},Object.defineProperties(i.prototype,r),i}(function(t){function e(e,i){t.call(this,e,i),this.frames=new Qx(this.name,this.path)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={type:{},__objName:{}};return i.type.get=function(){return"trajectory"},i.__objName.get=function(){return"frames"},Object.defineProperties(e.prototype,i),e}(xx));ff.add("dcd",t_);var e_=function(t){function e(e,i){var r=i||{};t.call(this,e,r),this.volume=new Vg(this.name,this.path),this.voxelSize=dn(r.voxelSize,1)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={type:{},__objName:{}};return i.type.get=function(){return"volume"},i.__objName.get=function(){return"volume"},e.prototype._afterParse=function(){this.volume.setMatrix(this.getMatrix())},e.prototype.getMatrix=function(){return new v},Object.defineProperties(e.prototype,i),e}(xx),i_=function(e){function i(){e.apply(this,arguments)}e&&(i.__proto__=e),i.prototype=Object.create(e&&e.prototype),i.prototype.constructor=i;var r={type:{}};return r.type.get=function(){return"cube"},i.prototype._parse=function(){function e(t,e){var i=n[t].trim().split(a)[e];return parseFloat(i)}function i(t,e,i){for(var r=t;r<e;++r){var n=i[r].trim();if(""!==n&&h>=o.atomCount+6+l)for(var s=0,p=(n=n.split(a)).length;s<p;++s)1!==n.length&&(c[u]=parseFloat(n[s]),++u);++h}}t.Debug&&cf.time("CubeParser._parse "+this.name);var r=this.volume,n=this.streamer.peekLines(6),o={},a=/\s+/,s=.529177210859*this.voxelSize;o.atomCount=Math.abs(e(2,0)),o.originX=.529177210859*e(2,1),o.originY=.529177210859*e(2,2),o.originZ=.529177210859*e(2,3),o.NVX=e(3,0),o.NVY=e(4,0),o.NVZ=e(5,0),o.basisX=new g(e(3,1),e(3,2),e(3,3)).multiplyScalar(s),o.basisY=new g(e(4,1),e(4,2),e(4,3)).multiplyScalar(s),o.basisZ=new g(e(5,1),e(5,2),e(5,3)).multiplyScalar(s);var c=new Float32Array(o.NVX*o.NVY*o.NVZ),u=0,h=0,l=e(2,0)>0?0:1;this.streamer.eachChunkOfLines(function(t){i(0,t.length,t)}),r.header=o,r.setData(c,o.NVZ,o.NVY,o.NVX),t.Debug&&cf.timeEnd("CubeParser._parse "+this.name)},i.prototype.getMatrix=function(){var t=this.volume.header,e=new v;return e.multiply((new v).makeTranslation(t.originX,t.originY,t.originZ)),e.multiply((new v).makeBasis(t.basisZ,t.basisY,t.basisX)),e},Object.defineProperties(i.prototype,r),i}(e_);ff.add("cub",i_),ff.add("cube",i_);var r_=function(e){function i(){e.apply(this,arguments)}e&&(i.__proto__=e),i.prototype=Object.create(e&&e.prototype),i.prototype.constructor=i;var r={type:{}};return r.type.get=function(){return"dsn6"},i.prototype._parse=function(){t.Debug&&cf.time("Dsn6Parser._parse "+this.name);var e=this.streamer.data;e instanceof Uint8Array&&(e=e.buffer);var i,r,n=this.volume,o={},a=new Int16Array(e),s=new Uint8Array(e),c=String.fromCharCode.apply(null,s.subarray(0,512));if(c.startsWith(":-)"))o.xStart=parseInt(c.substr(10,5)),o.yStart=parseInt(c.substr(15,5)),o.zStart=parseInt(c.substr(20,5)),o.xExtent=parseInt(c.substr(32,5)),o.yExtent=parseInt(c.substr(38,5)),o.zExtent=parseInt(c.substr(42,5)),o.xRate=parseInt(c.substr(52,5)),o.yRate=parseInt(c.substr(58,5)),o.zRate=parseInt(c.substr(62,5)),o.xlen=parseFloat(c.substr(73,10))*this.voxelSize,o.ylen=parseFloat(c.substr(83,10))*this.voxelSize,o.zlen=parseFloat(c.substr(93,10))*this.voxelSize,o.alpha=parseFloat(c.substr(103,10)),o.beta=parseFloat(c.substr(113,10)),o.gamma=parseFloat(c.substr(123,10)),i=parseFloat(c.substr(138,12))/100,r=parseInt(c.substr(155,8));else{if(100!==a[18])for(var u=0,h=a.length;u<h;++u){var l=a[u];a[u]=(255&l)<<8|l>>8&255}o.xStart=a[0],o.yStart=a[1],o.zStart=a[2],o.xExtent=a[3],o.yExtent=a[4],o.zExtent=a[5],o.xRate=a[6],o.yRate=a[7],o.zRate=a[8];var p=1/a[17],d=p*this.voxelSize;o.xlen=a[9]*d,o.ylen=a[10]*d,o.zlen=a[11]*d,o.alpha=a[12]*p,o.beta=a[13]*p,o.gamma=a[14]*p,i=a[15]/100,r=a[16]}n.header=o,cf.log(o,i,r);for(var f=new Float32Array(o.xExtent*o.yExtent*o.zExtent),m=512,g=Math.ceil(o.xExtent/8),v=Math.ceil(o.yExtent/8),y=Math.ceil(o.zExtent/8),b=0;b<y;++b)for(var x=0;x<v;++x)for(var _=0;_<g;++_)for(var w=0;w<8;++w)for(var S=8*b+w,A=0;A<8;++A)for(var M=8*x+A,P=0;P<8;++P){var T=8*_+P;if(!(T<o.xExtent&&M<o.yExtent&&S<o.zExtent)){m+=8-P;break}f[(T*o.yExtent+M)*o.zExtent+S]=(s[m]-r)/i,++m}n.setData(f,o.zExtent,o.yExtent,o.xExtent),t.Debug&&cf.timeEnd("Dsn6Parser._parse "+this.name)},i.prototype.getMatrix=function(){var t=this.volume.header,e=[t.xlen,0,0],i=[t.ylen*Math.cos(Math.PI/180*t.gamma),t.ylen*Math.sin(Math.PI/180*t.gamma),0],r=[t.zlen*Math.cos(Math.PI/180*t.beta),t.zlen*(Math.cos(Math.PI/180*t.alpha)-Math.cos(Math.PI/180*t.gamma)*Math.cos(Math.PI/180*t.beta))/Math.sin(Math.PI/180*t.gamma),0];r[2]=Math.sqrt(t.zlen*t.zlen*Math.sin(Math.PI/180*t.beta)*Math.sin(Math.PI/180*t.beta)-r[1]*r[1]);var n=[0,e,i,r],o=[0,t.xRate,t.yRate,t.zRate],a=[0,1,2,3],s=new v;return s.set(n[a[1]][0]/o[a[1]],n[a[2]][0]/o[a[2]],n[a[3]][0]/o[a[3]],0,n[a[1]][1]/o[a[1]],n[a[2]][1]/o[a[2]],n[a[3]][1]/o[a[3]],0,n[a[1]][2]/o[a[1]],n[a[2]][2]/o[a[2]],n[a[3]][2]/o[a[3]],0,0,0,0,1),s.multiply((new v).makeRotationY(Gn(90))),s.multiply((new v).makeTranslation(-t.zStart,t.yStart,t.xStart)),s.multiply((new v).makeScale(-1,1,1)),s},Object.defineProperties(i.prototype,r),i}(e_);ff.add("dsn6",r_),ff.add("brix",r_);var n_=function(e){function i(){e.apply(this,arguments)}e&&(i.__proto__=e),i.prototype=Object.create(e&&e.prototype),i.prototype.constructor=i;var r={type:{}};return r.type.get=function(){return"dx"},i.prototype._parse=function(){function e(t,e,i){for(var r=t;r<e;++r){if(h<c&&l>a){var n=i[r].trim();if(""!==n)for(var o=n.split(s),p=0,d=o.length;p<d;++p)u[h]=parseFloat(o[p]),++h}++l}}t.Debug&&cf.time("DxParser._parse "+this.name);var i=this.volume,r=this.streamer.peekLines(30),n=this.parseHeaderLines(r),o=this.volume.header,a=n.dataLineStart,s=/\s+/,c=o.nx*o.ny*o.nz,u=new Float32Array(c),h=0,l=0;this.streamer.eachChunkOfLines(function(t){e(0,t.length,t)}),i.setData(u,o.nz,o.ny,o.nx),t.Debug&&cf.timeEnd("DxParser._parse "+this.name)},i.prototype.parseHeaderLines=function(t){for(var e=this,i={},r=t.length,n=0,o=0,a=0,s=0;s<r;++s){var c,u=t[s];if(u.startsWith("object 1"))c=u.split(/\s+/),i.nx=parseInt(c[5]),i.ny=parseInt(c[6]),i.nz=parseInt(c[7]);else if(u.startsWith("origin"))c=u.split(/\s+/),i.xmin=parseFloat(c[1]),i.ymin=parseFloat(c[2]),i.zmin=parseFloat(c[3]);else if(u.startsWith("delta"))c=u.split(/\s+/),0===a?i.hx=parseFloat(c[1])*e.voxelSize:1===a?i.hy=parseFloat(c[2])*e.voxelSize:2===a&&(i.hz=parseFloat(c[3])*e.voxelSize),a+=1;else if(u.startsWith("object 3")){n=s,o+=u.length+1;break}o+=u.length+1}return this.volume.header=i,{dataLineStart:n,headerByteCount:o}},i.prototype.getMatrix=function(){var t=this.volume.header,e=new v;return e.multiply((new v).makeRotationY(Gn(90))),e.multiply((new v).makeTranslation(-t.zmin,t.ymin,t.xmin)),e.multiply((new v).makeScale(-t.hz,t.hy,t.hx)),e},Object.defineProperties(i.prototype,r),i}(e_);ff.add("dx",n_);var o_=function(e){function i(){e.apply(this,arguments)}e&&(i.__proto__=e),i.prototype=Object.create(e&&e.prototype),i.prototype.constructor=i;var r={type:{}};return r.type.get=function(){return"dxbin"},i.prototype._parse=function(){t.Debug&&cf.time("DxbinParser._parse "+this.name);var e=this.streamer.data;e instanceof Uint8Array&&(e=e.buffer);for(var i=Tn(new Uint8Array(e,0,1e3)),r=this.parseHeaderLines(i),n=this.volume.header,o=r.headerByteCount,a=n.nx*n.ny*n.nz,s=new DataView(e),c=new Float32Array(a),u=0;u<a;++u)c[u]=s.getFloat64(8*u+o,!0);this.volume.setData(c,n.nz,n.ny,n.nx),t.Debug&&cf.timeEnd("DxbinParser._parse "+this.name)},Object.defineProperties(i.prototype,r),i}(n_);ff.add("dxbin",o_);var a_=function(e){function i(){e.apply(this,arguments)}e&&(i.__proto__=e),i.prototype=Object.create(e&&e.prototype),i.prototype.constructor=i;var r={type:{}};return r.type.get=function(){return"mrc"},i.prototype._parse=function(){t.Debug&&cf.time("MrcParser._parse "+this.name);var e=this.streamer.data;e instanceof Uint8Array&&(e=e.buffer);var i=this.volume,r={},n=new Int32Array(e,0,56),o=new Float32Array(e,0,56),a=new DataView(e);if(r.MAP=String.fromCharCode(a.getUint8(208),a.getUint8(209),a.getUint8(210),a.getUint8(211)),r.MACHST=[a.getUint8(212),a.getUint8(213)],17===r.MACHST[0]&&17===r.MACHST[1])for(var s=e.byteLength,c=0;c<s;c+=4)a.setFloat32(c,a.getFloat32(c),!0);r.NX=n[0],r.NY=n[1],r.NZ=n[2],r.MODE=n[3],r.NXSTART=n[4],r.NYSTART=n[5],r.NZSTART=n[6],r.MX=n[7],r.MY=n[8],r.MZ=n[9],r.xlen=o[10]*this.voxelSize,r.ylen=o[11]*this.voxelSize,r.zlen=o[12]*this.voxelSize,r.alpha=o[13],r.beta=o[14],r.gamma=o[15],r.MAPC=n[16],r.MAPR=n[17],r.MAPS=n[18],r.DMIN=o[19],r.DMAX=o[20],r.DMEAN=o[21],r.ISPG=n[22],r.NSYMBT=n[23],r.LSKFLG=n[24],r.originX=o[49],r.originY=o[50],r.originZ=o[51],r.ARMS=o[54],i.header=r;var u;if(2===r.MODE)u=new Float32Array(e,1024+r.NSYMBT,r.NX*r.NY*r.NZ);else if(0===r.MODE){if(u=new Float32Array(new Int8Array(e,1024+r.NSYMBT,r.NX*r.NY*r.NZ)),-128===n[39]&&127===n[40])for(var h=(r.DMAX-r.DMIN)/255,l=.5*(r.DMIN+r.DMAX+h),p=0,d=u.length;p<d;++p)u[p]=h*u[p]+l}else cf.error("MrcParser unknown mode",r.MODE);i.setData(u,r.NX,r.NY,r.NZ),t.Debug&&cf.timeEnd("MrcParser._parse "+this.name)},i.prototype.getMatrix=function(){var t=this.volume.header,e=[t.xlen,0,0],i=[t.ylen*Math.cos(Math.PI/180*t.gamma),t.ylen*Math.sin(Math.PI/180*t.gamma),0],r=[t.zlen*Math.cos(Math.PI/180*t.beta),t.zlen*(Math.cos(Math.PI/180*t.alpha)-Math.cos(Math.PI/180*t.gamma)*Math.cos(Math.PI/180*t.beta))/Math.sin(Math.PI/180*t.gamma),0];r[2]=Math.sqrt(t.zlen*t.zlen*Math.sin(Math.PI/180*t.beta)*Math.sin(Math.PI/180*t.beta)-r[1]*r[1]);var n=[0,e,i,r],o=[0,t.MX,t.MY,t.MZ],a=[0,t.MAPC,t.MAPR,t.MAPS],s=new v;return s.set(n[a[1]][0]/o[a[1]],n[a[2]][0]/o[a[2]],n[a[3]][0]/o[a[3]],0,n[a[1]][1]/o[a[1]],n[a[2]][1]/o[a[2]],n[a[3]][1]/o[a[3]],0,n[a[1]][2]/o[a[1]],n[a[2]][2]/o[a[2]],n[a[3]][2]/o[a[3]],0,0,0,0,1),s.setPosition(new g(t.originX,t.originY,t.originZ)),s.multiply((new v).makeTranslation(t.NXSTART,t.NYSTART,t.NZSTART)),s},Object.defineProperties(i.prototype,r),i}(e_);ff.add("mrc",a_),ff.add("ccp4",a_),ff.add("map",a_);var s_=function(e){function i(){e.apply(this,arguments)}e&&(i.__proto__=e),i.prototype=Object.create(e&&e.prototype),i.prototype.constructor=i;var r={type:{}};return r.type.get=function(){return"xplor"},i.prototype._parse=function(){function e(t){return t.trim().split(s).map(parseFloat)}function i(t,e,i){for(var r=t;r<e;++r){var n=i[r];if(v>=c&&(v-c)%y!=0&&g<f)for(var o=0;o<6;++o)m[g]=parseFloat(n.substr(12*o,12)),++g;++v}}t.Debug&&cf.time("XplorParser._parse "+this.name);var r,n=this.volume,o=this.streamer.peekLines(8),a={},s=/\s+/,c=(r=o[2].startsWith("REMARKS")?parseInt(o[1].substring(0,8))+2:5)+3,u=e(o[r]);a.NA=u[0],a.AMIN=u[1],a.AMAX=u[2],a.NB=u[3],a.BMIN=u[4],a.BMAX=u[5],a.NC=u[6],a.CMIN=u[7],a.CMAX=u[8];var h=e(o[r+1]);a.a=h[0]*this.voxelSize,a.b=h[1]*this.voxelSize,a.c=h[2]*this.voxelSize,a.alpha=h[3],a.beta=h[4],a.gamma=h[5];var l=a.AMAX-a.AMIN+1,p=a.BMAX-a.BMIN+1,d=a.CMAX-a.CMIN+1,f=l*p*d,m=new Float32Array(f),g=0,v=0,y=1+l*p/6;this.streamer.eachChunkOfLines(function(t){i(0,t.length,t)}),n.header=a,n.setData(m,l,p,d),t.Debug&&cf.timeEnd("XplorParser._parse "+this.name)},i.prototype.getMatrix=function(){var t=this.volume.header,e=[t.a,0,0],i=[t.b*Math.cos(Math.PI/180*t.gamma),t.b*Math.sin(Math.PI/180*t.gamma),0],r=[t.c*Math.cos(Math.PI/180*t.beta),t.c*(Math.cos(Math.PI/180*t.alpha)-Math.cos(Math.PI/180*t.gamma)*Math.cos(Math.PI/180*t.beta))/Math.sin(Math.PI/180*t.gamma),0];r[2]=Math.sqrt(t.c*t.c*Math.sin(Math.PI/180*t.beta)*Math.sin(Math.PI/180*t.beta)-r[1]*r[1]);var n=[0,e,i,r],o=[0,t.NA,t.NB,t.NC],a=[0,1,2,3],s=new v;return s.set(n[a[1]][0]/o[a[1]],n[a[2]][0]/o[a[2]],n[a[3]][0]/o[a[3]],0,n[a[1]][1]/o[a[1]],n[a[2]][1]/o[a[2]],n[a[3]][1]/o[a[3]],0,n[a[1]][2]/o[a[1]],n[a[2]][2]/o[a[2]],n[a[3]][2]/o[a[3]],0,0,0,0,1),s.multiply((new v).makeTranslation(t.AMIN,t.BMIN,t.CMIN)),s},Object.defineProperties(i.prototype,r),i}(e_);ff.add("xplor",s_),ff.add("cns",s_);var c_=function(t){function e(e,i){t.call(this,e,i),this.loader=this.getLoader(),this.surface=new jg(this.name,this.path)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={type:{},__objName:{}};return i.type.get=function(){return"surface"},i.__objName.get=function(){return"surface"},e.prototype._parse=function(){var t=this.loader.parse(this.streamer.asText());this.surface.fromGeometry(t)},Object.defineProperties(e.prototype,i),e}(xx);Mc.prototype={constructor:Mc,setPath:function(t){this.path=t},_createParserState:function(){var t={objects:[],object:{},vertices:[],normals:[],startObject:function(t,e){if(this.object&&!1===this.object.fromDeclaration)return this.object.name=t,void(this.object.fromDeclaration=!1!==e);this.object={name:t||"",geometry:{vertices:[],normals:[]},fromDeclaration:!1!==e},this.objects.push(this.object)},parseVertexIndex:function(t,e){var i=parseInt(t,10);return 3*(i>=0?i-1:i+e/3)},parseNormalIndex:function(t,e){var i=parseInt(t,10);return 3*(i>=0?i-1:i+e/3)},addVertex:function(t,e,i){var r=this.vertices,n=this.object.geometry.vertices;n.push(r[t+0]),n.push(r[t+1]),n.push(r[t+2]),n.push(r[e+0]),n.push(r[e+1]),n.push(r[e+2]),n.push(r[i+0]),n.push(r[i+1]),n.push(r[i+2])},addVertexLine:function(t){var e=this.vertices,i=this.object.geometry.vertices;i.push(e[t+0]),i.push(e[t+1]),i.push(e[t+2])},addNormal:function(t,e,i){var r=this.normals,n=this.object.geometry.normals;n.push(r[t+0]),n.push(r[t+1]),n.push(r[t+2]),n.push(r[e+0]),n.push(r[e+1]),n.push(r[e+2]),n.push(r[i+0]),n.push(r[i+1]),n.push(r[i+2])},addFace:function(t,e,i,r,n,o,a,s){var c,u=this.vertices.length,h=this.parseVertexIndex(t,u),l=this.parseVertexIndex(e,u),p=this.parseVertexIndex(i,u);if(void 0===r?this.addVertex(h,l,p):(c=this.parseVertexIndex(r,u),this.addVertex(h,l,c),this.addVertex(l,p,c)),void 0!==n){var d=this.normals.length;h=this.parseNormalIndex(n,d),l=n===o?h:this.parseNormalIndex(o,d),p=n===a?h:this.parseNormalIndex(a,d),void 0===r?this.addNormal(h,l,p):(c=this.parseNormalIndex(s,d),this.addNormal(h,l,c),this.addNormal(l,p,c))}},addLineGeometry:function(t){var e=this;this.object.geometry.type="Line";for(var i=this.vertices.length,r=0,n=t.length;r<n;r++)e.addVertexLine(e.parseVertexIndex(t[r],i))}};return t.startObject("",!1),t},parse:function(t){var e=this,i=this._createParserState();-1!==t.indexOf("\r\n")&&(t=t.replace(/\r\n/g,"\n")),-1!==t.indexOf("\\\n")&&(t=t.replace(/\\\n/g,""));var r,n,o=t.split("\n"),a="",s="",c="",u=[],h="function"==typeof"".trimLeft;for(r=0,n=o.length;r<n;r++)if(a=o[r],a=h?a.trimLeft():a.trim(),0!==a.length&&"#"!==(s=a.charAt(0)))if("v"===s){if(" "===(c=a.charAt(1))&&null!==(u=e.regexp.vertex_pattern.exec(a)))i.vertices.push(parseFloat(u[1]),parseFloat(u[2]),parseFloat(u[3]));else if("n"===c&&null!==(u=e.regexp.normal_pattern.exec(a)))i.normals.push(parseFloat(u[1]),parseFloat(u[2]),parseFloat(u[3]));else if("t"!==c||null===(u=e.regexp.uv_pattern.exec(a)))throw new Error("Unexpected vertex/normal/uv line: '"+a+"'")}else if("f"===s)if(null!==(u=e.regexp.face_vertex_uv_normal.exec(a)))i.addFace(u[1],u[4],u[7],u[10],u[3],u[6],u[9],u[12]);else if(null!==(u=e.regexp.face_vertex_uv.exec(a)));else if(null!==(u=e.regexp.face_vertex_normal.exec(a)))i.addFace(u[1],u[3],u[5],u[7],u[2],u[4],u[6],u[8]);else{if(null===(u=e.regexp.face_vertex.exec(a)))throw new Error("Unexpected face line: '"+a+"'");i.addFace(u[1],u[2],u[3],u[4])}else if("l"===s){var l=a.substring(1).trim().split(" "),p=[],d=[];if(-1===a.indexOf("/"))p=l;else for(var f=0,m=l.length;f<m;f++){var g=l[f].split("/");""!==g[0]&&p.push(g[0]),""!==g[1]&&d.push(g[1])}i.addLineGeometry(p,d)}else if(null!==(u=e.regexp.object_pattern.exec(a))){var v=u[0].substr(1).trim();i.startObject(v)}else if(e.regexp.material_use_pattern.test(a));else if(e.regexp.material_library_pattern.test(a));else if(null===(u=e.regexp.smoothing_pattern.exec(a))){if("\0"===a)continue;throw new Error("Unexpected line: '"+a+"'")}var y=[];for(r=0,n=i.objects.length;r<n;r++){var b=i.objects[r].geometry;if(0!==b.vertices.length){var x=new Ct;x.addAttribute("position",new _t(new Float32Array(b.vertices),3)),b.normals.length>0?x.addAttribute("normal",new _t(new Float32Array(b.normals),3)):x.computeVertexNormals(),y.push(x)}}return y}};var u_=function(t){function e(){t.apply(this,arguments)}t&&(e.__proto__=t),e.prototype=Object.create(t&&t.prototype),e.prototype.constructor=e;var i={type:{}};return i.type.get=function(){return"obj"},e.prototype.getLoader=function(){return new Mc},Object.defineProperties(e.prototype,i),e}(c_);ff.add("obj",u_),Pc.prototype={constructor:Pc,setPropertyNameMapping:function(t){this.propertyNameMapping=t},bin2str:function(t){for(var e=new Uint8Array(t),i="",r=0;r<t.byteLength;r++)i+=String.fromCharCode(e[r]);return i},isASCII:function(t){return"ascii"===this.parseHeader(this.bin2str(t)).format},parse:function(t){return t instanceof ArrayBuffer?this.isASCII(t)?this.parseASCII(this.bin2str(t)):this.parseBinary(t):this.parseASCII(t)},parseHeader:function(t){var e=this,i="",r=0,n=/ply([\s\S]*)end_header\s/.exec(t);null!==n&&(i=n[1],r=n[0].length);for(var o,a,s,c={comments:[],elements:[],headerLength:r},u=i.split("\n"),h=0;h<u.length;h++){var l=u[h];if(""!==(l=l.trim()))switch(s=l.split(/\s+/),a=s.shift(),l=s.join(" "),a){case"format":c.format=s[0],c.version=s[1];break;case"comment":c.comments.push(l);break;case"element":void 0!==o&&c.elements.push(o),(o={}).name=s[0],o.count=parseInt(s[1]),o.properties=[];break;case"property":o.properties.push(function(t,e){var i={type:t[0]};return"list"===i.type?(i.name=t[3],i.countType=t[1],i.itemType=t[2]):i.name=t[1],i.name in e&&(i.name=e[i.name]),i}(s,e.propertyNameMapping));break;default:console.log("unhandled",a,s)}}return void 0!==o&&c.elements.push(o),c},parseASCIINumber:function(t,e){switch(e){case"char":case"uchar":case"short":case"ushort":case"int":case"uint":case"int8":case"uint8":case"int16":case"uint16":case"int32":case"uint32":return parseInt(t);case"float":case"double":case"float32":case"float64":return parseFloat(t)}},parseASCIIElement:function(t,e){for(var i=this,r=e.split(/\s+/),n={},o=0;o<t.length;o++)if("list"===t[o].type){for(var a=[],s=i.parseASCIINumber(r.shift(),t[o].countType),c=0;c<s;c++)a.push(i.parseASCIINumber(r.shift(),t[o].itemType));n[t[o].name]=a}else n[t[o].name]=i.parseASCIINumber(r.shift(),t[o].type);return n},parseASCII:function(t){var e,i=this,r=new Et,n=this.parseHeader(t),o="";null!==(e=/end_header\s([\s\S]*)$/.exec(t))&&(o=e[1]);var a=o.split("\n"),s=0,c=0;r.useColor=!1;for(var u=0;u<a.length;u++){var h=a[u];if(""!==(h=h.trim())){c>=n.elements[s].count&&(s++,c=0);var l=i.parseASCIIElement(n.elements[s].properties,h);i.handleElement(r,n.elements[s].name,l),c++}}return this.postProcess(r)},postProcess:function(t){if(t.useColor){for(var e=0;e<t.faces.length;e++)t.faces[e].vertexColors=[t.colors[t.faces[e].a],t.colors[t.faces[e].b],t.colors[t.faces[e].c]];t.elementsNeedUpdate=!0}return t.computeBoundingSphere(),t},handleElement:function(t,e,i){if("vertex"===e){if(t.vertices.push(new g(i.x,i.y,i.z)),"red"in 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