Difference between revisions of "Team:Aix-Marseille"

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==Motivation==
 
==Motivation==
''Xylella fastidiosa'' is a major threat for agriculture.
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''Xylella fastidiosa'' is a '''major threat for agriculture'''.
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This bacterium infects plants, causing a variety of diseases in '''wineyards''', '''olive orchards''' and in over 300 other species.
  
This bacterium infects plants, causing a variety of diseases in wineyards, olive orchards and many other species. This bacterium has been widespread in the Americas for many years and is also present in Asia.
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This bacterium has been widespread in the '''Americas''' for many years and is also present in '''Asia'''.
  
Although ''X. fastidiosa'' has been recognized as a serious pathogen, there is no effective cure. In fact, the only way to slow down the propagation of the disease is to burn the infected tree and at risk trees around, and massively use pesticides.
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In 2015, more than '''200 000 ha (494 210 ac)''' of European crops were lost because of this bacterium.
 
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First, we wanted to improve the detection of the disease. Secondly, we want to get rid of the bacterium. Thus we have nanobots specific to ''X. fastidiosa'', capable to inject toxic genes into it. Finaly, we disrupt the biofilm that causes the plants death,  by quenching the quorum sensing of the bacterium and by the use of an enzyme, that destroy the biofilm.
 
First, we wanted to improve the detection of the disease. Secondly, we want to get rid of the bacterium. Thus we have nanobots specific to ''X. fastidiosa'', capable to inject toxic genes into it. Finaly, we disrupt the biofilm that causes the plants death,  by quenching the quorum sensing of the bacterium and by the use of an enzyme, that destroy the biofilm.
  
Hence, KILL XYL simply detects, disrupt and kill ''Xylella fastidiosa''.
+
Hence, KILL XYL simply detects, disrupts and kills ''Xylella fastidiosa''.
 
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The human practice side of our project is crucial to our research. Indeed, we are attached to find an environmentally friendly cure for the olive trees. So we contacted associations of olive growers, to understand their needs and the expectation they have.
 
The human practice side of our project is crucial to our research. Indeed, we are attached to find an environmentally friendly cure for the olive trees. So we contacted associations of olive growers, to understand their needs and the expectation they have.
 
   
 
   
We also ask help from different expert to help us on our project. We think that the engagement with public is important. Thus we create a surveys but we also directly contact the public we different event.
+
We also ask help from different expert to help us on our project. We think that the engagement with public is important. Thus we create a survey but we also directly contacted the public at different events.
  
 
Finally, we tested our product in a model plant and we investigated the legal aspects necessary to get approval for commercialisation in the European Union.
 
Finally, we tested our product in a model plant and we investigated the legal aspects necessary to get approval for commercialisation in the European Union.

Revision as of 13:02, 20 October 2017

iGEM Aix-Marseille 2017

At Aix-Marseille University, we choose to use synthetic biology to cure trees from a disease caused by a plant pathogen called Xylella fastidiosa.

  • T--Aix-Marseille--home--olive.png
    350+ host plant species affected
  • T--Aix-Marseille--home--deadtree.png
    Outbreak area of 450 000 acres of olive crops in Italy (Apulia region)
  • T--Aix-Marseille--home--dollar.png
    US$ 104 million/year in terms of losses of vines and measures for disease prevention in California

Xylella fastidiosa is a major threat for agriculture.

This bacterium infects plants, causing a variety of diseases in wineyards, olive orchards and in over 300 other species.

This bacterium has been widespread in the Americas for many years and is also present in Asia.

In 2015, more than 200 000 ha (494 210 ac) of European crops were lost because of this bacterium.

Although X. fastidiosa has been recognized as a serious pathogen, there is no effective cure.

In fact, the only way to slow down the propagation of the disease is to burn the infected tree and at risk trees around, and massively use pesticides.

Given the current risk of X. fastidiosa spreading, our project is to develop an effective and environmentally friendly cure for the disease.

Aix-Marseille Université - projet FSDIE Collectivité territoriale de Corse