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| | + | <h1>Introduction</h1> |
| | + | <h6>To predict the designed system, iGEM TU Eindhoven developed a model to simulate the designed protein scaffold and its binding partner. The challenge is that there are many options of end products, making it impossible to apply an ordinary ODE-solver with differential equations. There are two approaches that we will introduce. The first is a simulation that we developed ourselves and that visualizes the system in a 2D simulation box.The second approach uses an already developed rule-based-model, which we adapted to our system.<br/> |
| | + | To get a more detailed description, go to the model page of <a href="https://2017.igem.org/Team:TU-Eindhoven/Model/2D_Simulation">“Simulation in 2D”</a> and <a href="https://2017.igem.org/Team:TU-Eindhoven/Model/Rule_based_model">“Rule based model”</a>, or continue with reading to get a short overview of the molecules that are simulated with the models. |
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| − | <div class="column full_size judges-will-not-evaluate">
| + | </h6> |
| − | <h3>★ ALERT! </h3>
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| − | <p>This page is used by the judges to evaluate your team for the <a href="https://2017.igem.org/Judging/Medals">medal criterion</a> or <a href="https://2017.igem.org/Judging/Awards"> award listed above</a>. </p>
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| − | <p> Delete this box in order to be evaluated for this medal criterion and/or award. See more information at <a href="https://2017.igem.org/Judging/Pages_for_Awards"> Instructions for Pages for awards</a>.</p>
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| − | <h1> Modeling</h1>
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| − | <p>Mathematical models and computer simulations provide a great way to describe the function and operation of BioBrick Parts and Devices. Synthetic Biology is an engineering discipline, and part of engineering is simulation and modeling to determine the behavior of your design before you build it. Designing and simulating can be iterated many times in a computer before moving to the lab. This award is for teams who build a model of their system and use it to inform system design or simulate expected behavior in conjunction with experiments in the wetlab.</p>
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| − | <h3> Gold Medal Criterion #3</h3>
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| − | <p>
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| − | To complete for the gold medal criterion #3, please describe your work on this page and fill out the description on your <a href="https://2017.igem.org/Judging/Judging_Form">judging form</a>. To achieve this medal criterion, you must convince the judges that your team has gained insight into your project from modeling. You may not convince the judges if your model does not have an effect on your project design or implementation.
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| − | </p>
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| − | <p>
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| − | Please see the <a href="https://2017.igem.org/Judging/Medals"> 2017 Medals Page</a> for more information.
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| − | </p>
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| − | </div>
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| − | <h3>Best Model Special Prize</h3>
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| − | <p>
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| − | To compete for the <a href="https://2017.igem.org/Judging/Awards">Best Model prize</a>, please describe your work on this page and also fill out the description on the <a href="https://2017.igem.org/Judging/Judging_Form">judging form</a>. Please note you can compete for both the gold medal criterion #3 and the best model prize with this page.
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| − | <br><br>
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| − | You must also delete the message box on the top of this page to be eligible for the Best Model Prize.
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| − | </p>
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| − | <h5> Inspiration </h5>
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| − | <p>
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| − | Here are a few examples from previous teams:
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| − | </p>
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| − | <ul>
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| − | <li><a href="https://2016.igem.org/Team:Manchester/Model">Manchester 2016</a></li>
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| − | <li><a href="https://2016.igem.org/Team:TU_Delft/Model">TU Delft 2016 </li>
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| − | <li><a href="https://2014.igem.org/Team:ETH_Zurich/modeling/overview">ETH Zurich 2014</a></li>
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| − | <li><a href="https://2014.igem.org/Team:Waterloo/Math_Book">Waterloo 2014</a></li>
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| − | </ul> | + | |
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