Difference between revisions of "Team:TokyoTech/HP"

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     <p style="font-family: Poppins;font-size: 16px">By integrating with our Human Practices and the results from our wet lab experiments and modeling, iGEM2017 Team TokyoTech have executed our project with improved design in accordance with comments from general public, and have strengthened the public engagement of a two-way dialogue between our team and the public through this summer. (See here to know how we integrated our project)
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     <p style="font-size: 16px; text-indent: 1em">This year, we tried to jump into as many chances as possible to learn more about role and value of synthetic biology and the future of this academic field. In this new information society, we can easily obtain knowledge on the Internet and many iGEMers may think the learning happens only in the labs or on the computers. That's sometimes true, but it's not always true that a bunch of information automatically comes to our pocket, which means we sometimes have to break free from the obsession with the project work.
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    <p style="font-size: 16px; text-indent: 1em">We can proudly say our integrated human practices helped us make progress in our project design. By integrating our human practices with the results from our wet lab experiments and modeling, iGEM2017 Team TokyoTech have executed our project with improved design in accordance with comments from general public, and have strengthened the public engagement of a two-way dialogue between our team and the public through this summer.
 
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    <p style="font-family: Poppins;font-size: 16px">1. At an early stage of our project design, we decided to establish co-culture system between bacteria and human cells regardless of the practical application. For 10 years, our team has used <i>E. coli</i> for the project. However, we had to use something new to adopt a paradigm shift in iGEM community. Thus, we added human cells to explore the interaction between them in our body.
 
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    <p style="font-family: Poppins;font-size: 16px">2. In May Festival held in University of Tokyo, we introduced our project to the general public in the poster session. The audiences gave us a lot of advice and valuable comments that later led us and our project to move forward. One of them advised us that we should apply the project for the field of therapeutics. That advice opened up a door for the application of our project which had hovered up a level of fundamental research.
 
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    <p style="font-family: Poppins;font-size: 16px">3. We had planned to use Caco2 cells derived from intestine, but our PI advised us that EAhy926 cells derived from vessels are better for the therapeutic application. We accepted that advice and started to culture the cells and transduced the constructs.
 
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    <p style="font-family: Poppins;font-size: 16px">4. Our PI gave us a chance to discuss the direction of our project with the experts from molecular biology in Keio University. At that time, our project had a problem of what we call "Cross-talk." Cross-talk is a phenomenon which in this case, human cells receive own signaling molecules which they already released. Some of the experts suggested to us that we should use a plant hormone to prevent it.
 
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    <p style="font-family: Poppins;font-size: 16px">5. Based on the advice from the experts, we decided to use iP(Isopentenyl adenine) as the alternative signaling molecule from human cells to <i>E. coli</i>.
 
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Revision as of 17:34, 29 October 2017

<!DOCTYPE html> Coli Sapiens

iGEM Tokyo Tech

Human Practices: Overview

Overview

This year, we tried to jump into as many chances as possible to learn more about role and value of synthetic biology and the future of this academic field. In this new information society, we can easily obtain knowledge on the Internet and many iGEMers may think the learning happens only in the labs or on the computers. That's sometimes true, but it's not always true that a bunch of information automatically comes to our pocket, which means we sometimes have to break free from the obsession with the project work.

We can proudly say our integrated human practices helped us make progress in our project design. By integrating our human practices with the results from our wet lab experiments and modeling, iGEM2017 Team TokyoTech have executed our project with improved design in accordance with comments from general public, and have strengthened the public engagement of a two-way dialogue between our team and the public through this summer.

Basic Human Practices

Integrated Human Practices

Fig. Roadmap of integrated human practices

Hajime Fujita: All Rights Reserved