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| + | {{SDU_CHINA}} |
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− | | + | <html> |
− | <html lang="en"> | + | |
| <head> | | <head> |
| <meta http-equiv="Content-Type" content="text/html; charset=utf-8" /> | | <meta http-equiv="Content-Type" content="text/html; charset=utf-8" /> |
| + | <title>SDU_CHINA</title> |
| | | |
| <style> | | <style> |
− | .bottom{position:relative} | + | .bottom{position:relative;text-align:center} |
− | .bottom .bar{width:100%;height:50px;top:0;background-color:#72616e;position:absolute;;z-index:2;font-family:"Comic Sans MS", cursive} | + | .bottom .bar{width:100%;height:70px;top:0px;background-color:#f6f6f6;display:absolute;z-index:2;position;fixed} |
− | .bottom .square {width: 160px; height:160px; background:#e54b4b;position:absolute;z-index:2;top:0;left:40px;}
| + | .bottom .bg{z-index:-2;display:block} |
− | .bottom .rectangle {width:1000px; height:100px; background:#19548f;position:absolute;z-index:0;top:160px;left:40px;} | + | .bgg{z-index:-2;display:block;positon:relative} |
− | .bottom .logo{z-index:3;top:10px;left:50px;position:absolute;} | + | |
− | .bottom .farewell{letter-spacing:3px;top:20px;left:40px;position:relative;font-size:50px;color:white;font-family:Verdana, Geneva, sans-serif}
| + | |
| | | |
− | .menuDiv { | + | .abstract{margin:5em 20% auto 20%;position:relative} |
− | overflow: hidden;
| + | .abstract .title{position:relative;margin:0 auto auto 0;color:#0172b4;font-family:Arial, Helvetica, sans-serif;font-size:30px} |
− | display:inline-block;
| + | .abstract .content{margin:0 auto;letter-spacing:0.02em;word-spacing:0.2em;font-family:Segoe, "Segoe UI", "DejaVu Sans", "Trebuchet MS", Verdana, "sans-serif";font-size:1.2em;word-wrap: break-word ;position:relative;text-indent:2em;text-align:left} |
− | padding-left:200px;
| + | .video{text-align:center;z-index:2;positon:relative} |
− | float:left;
| + | .foot{margin:10% auto auto auto} |
− | margin-right:20px;
| + | |
− | z-index:2;
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− | font-size:30px
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− | font-family:Tahoma, Geneva, sans-serif}
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− |
| + | |
− | .menuDiv a{text-decoration: none;}
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− | .menuDiv ul,.menuDiv li {
| + | |
− | list-style: none;
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− | padding: 0px;
| + | |
− | float: right;}
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− | .menuDiv > ul > li > ul { | + | |
− | position: absolute;
| + | |
− | display: none;}
| + | |
− | .menuDiv > ul > li > ul > li { | + | |
− | float: none;}
| + | |
− | .menuDiv > ul > li:hover ul {
| + | |
− | display: block;}
| + | |
− | .menuDiv > ul > li > a {
| + | |
− | width:100px;
| + | |
− | margin-top:-4px;
| + | |
− | line-height:50px;
| + | |
− | color: white;
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− | background-color: #72616e;
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− | text-align: center;
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− | border-left: none;
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− | display: block;
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− | font-size:18px;
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− | }
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− | .menuDiv > ul > li:first-child > a {
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− | border-left: none;
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− | }
| + | |
− | .menuDiv > ul > li > a:hover {
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− | color: #966;
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− | background-color: #999;
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− | }
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− | .menuDiv > ul > li > ul > li > a { | + | |
− | width: 150px;
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− | font-size:18px;
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− | line-height: 50px;
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− | color: white;
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− | background-color:#72616e;
| + | |
− | text-align: center;
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− | border:none;
| + | |
− | display: block;
| + | |
− | margin-left:-40px;
| + | |
− | }
| + | |
− | .menuDiv > ul > li > ul > li:first-child > a {
| + | |
− | border-top:no;
| + | |
− | }
| + | |
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− | .menuDiv > ul > li > ul > li > a:hover {
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− | color:#966;
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− | background-color: #999;
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− | }
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− |
| |
− | .abstract{margin:0 10% auto 10% ;position:relative;padding-top:200px;}
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− | .abstract .title{position:relative;margin:0 auto auto 0;color:#660;font-family:Arial, Helvetica, sans-serif;font-size:30px}
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− | .abstract .content{top:10px;position:relative;word-spacing:2px;letter-spacing:0.3px;font-family:"Palatino Linotype", "Book Antiqua", Palatino, serif, Times, serif;font-size:20px;word-break:break-all}
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− | .abstract .icon{position:relative;margin:0px auto}
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− | .abstract .subicon{position:relative;float:left;margin-left:100px}
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− |
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− | .foot{width:100%;height:200px;background:#0066CC;position:fixed"}
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| </style> | | </style> |
| </head> | | </head> |
| + | |
| <body> | | <body> |
| <div class="bottom"> | | <div class="bottom"> |
− | <div class="bar">
| + | |
− | <div class="menuDiv">
| + | |
− | <ul>
| + | <div class="bg" > |
− | <li>
| + | <img src="https://static.igem.org/mediawiki/2017/4/4c/Bg.jpeg" style="width:100%;height:auto" style="width:100%;height:auto"> |
− | <a href="https://2017.igem.org/Team:SDU_CHINA">Home</a> </li>
| + | |
− | <li>
| + | |
− | <a href="https://2017.igem.org/Team:SDU_CHINA/project">Project</a>
| + | |
− | <ul>
| + | |
− | <li><a href="#">Description</a></li>
| + | |
− | <li><a href="#">Design</a></li>
| + | |
− | <li><a href="#">Experiment</a></li>
| + | |
− | <li><a href="#">Results</a></li>
| + | |
− | <li><a href="#">Notebook</a></li>
| + | |
− | </ul>
| + | |
− | </li>
| + | |
− | <li>
| + | |
− | <a href="https://2017.igem.org/Team:SDU_CHINA/model">Model</a>
| + | |
− | </li>
| + | |
− | <li>
| + | |
− | <a href="https://2017.igem.org/Team:SDU_CHINA/interlab">Interlab</a>
| + | |
− | </li>
| + | |
− | <li>
| + | |
− | <a href="https://2017.igem.org/Team:SDU_CHINA/parts">Parts</a>
| + | |
− | <ul>
| + | |
− | <li><a href="https://2017.igem.org/Team:SDU_CHINA/basicparts">Basic parts</a></li>
| + | |
− | <li><a href="https://2017.igem.org/Team:SDU_CHINA/compositeparts">Composite parts</a></li>
| + | |
− | </ul>
| + | |
− | </li>
| + | |
− | <li>
| + | |
− | <a href="https://2017.igem.org/Team:SDU_CHINA/practice">Practice</a>
| + | |
− | <ul>
| + | |
− | <li><a href="https://2017.igem.org/Team:SDU_CHINA/education">Public education</a></li>
| + | |
− | <li><a href="https://2017.igem.org/Team:SDU_CHINA/activity">Society activity</a></li>
| + | |
− | </ul>
| + | |
− | </li>
| + | |
− | <li>
| + | |
− | <a href="https://2017.igem.org/Team:SDU_CHINA/awards">Awards</a>
| + | |
− | </li>
| + | |
− | </ul>
| + | |
− | </div>
| + | |
− | </div>
| + | |
− | <div class="square"></div>
| + | |
− | <div class="logo"><img src="https://static.igem.org/mediawiki/2017/4/40/LOGO.png" style="width:140px;height:140px;"></div>
| + | |
− | <div><img src="https://static.igem.org/mediawiki/2017/d/d6/SDU_main_title.png" style="z-index:0;width:60%;top:100px;left:300px;position:relative;z-index:1"></div>
| + | |
− | <div><img src="https://static.igem.org/mediawiki/2017/a/ab/SDU_home_keyboard.png" style="width:60%;position:relative;top:120px;left:250px"></div>
| + | |
− | </div>、
| + | |
− | | + | |
− | <div class="abstract" >
| + | |
− | <div class="title"><b>Abstract</b></div>
| + | |
− | <div class="content"><p>Non-small cell lung cancer (NSCLC) is the
| + | |
− | leading cause of cancer-related death among the world with low
| + | |
− | overall survival rate. In NSCLC, immunotherapy has been indicated
| + | |
− | as a potential therapy for treating in situ solid tumor. Previous
| + | |
− | research has indicated that tumor cells can express programmed
| + | |
− | death-1 ligand (PD-L1) to diminish T-cell effector functions and
| + | |
− | therefore to achieve immune escape. In our project, gene edition
| + | |
− | will be incorporated with immunotherapy to eradicate the immune
| + | |
− | escape occurred in NSCLC. By constructing plasmid with
| + | |
− | Crispr-Cas 9 system targeting the gene coding for PD-L1, the
| + | |
− | expression of PD-L1 will be inhibited to restore immune system
| + | |
− | supervision. To ensure the biosafety, another plasmid with
| + | |
− | Crsipr-Cas 9 system to cut off the housekeeping gene of two
| + | |
− | plasmids will be also constructed to suicide both plasmid when
| + | |
− | PD-L1 expression was not detectable. Better therapeutic effects of
| + | |
− | immunotherapy to conquer the NSCLC are hoped to be achieved.</p></div>
| + | |
| </div> | | </div> |
| | | |
− | <br> <br> <br> <br> <br> <br> <br> <br>
| + | <div class="c"><img src="https://static.igem.org/mediawiki/2017/9/92/Abstract.jpeg" style="width:100%;height:auto"></div> |
| | | |
| | | |
− | <div>
| + | |
− | <div class="foot">
| + | <div class="video" style="background:url('https://static.igem.org/mediawiki/2017/5/55/Bggg.jpeg');background-size:100%;padding-top:12em;height:480px;background-repeat:none"> |
− | </div>
| + | <video src="https://static.igem.org/mediawiki/2017/1/10/Video.mp4" width="48%" controls="controls"> |
| </div> | | </div> |
| | | |
| + | |
| + | <div class="foot"><img src="https://static.igem.org/mediawiki/2017/0/04/Sponsor.jpeg" style="width:80%;height:auto;margin-top:-5em"></div> |
| + | <br><br> |
| + | <div class="footest"><img src="https://static.igem.org/mediawiki/2017/c/c0/Foot.jpeg" style="width:100%;height:auto"></div> |
| + | |
| + | </div> |
| </body> | | </body> |
| </html> | | </html> |