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| <style> | | <style> |
− | .bottom{position:relative} | + | .bottom{position:relative;text-align:center} |
− | .bottom .bar{width:100%;height:70px;top:0px;background-color:#f6f6f6;position:absolute;z-index:0;display:inline-block;} | + | .bottom .bar{width:100%;height:70px;top:0px;background-color:#f6f6f6;display:absolute;z-index:2;position;fixed} |
− | .bottom .bg{position:static} | + | .bottom .bg{z-index:-2;display:block} |
− |
| + | .bgg{z-index:-2;display:block;positon:relative} |
− | .menuDiv {display:inline-block;position:absolute;overflow:hidden;left:8%;top:0px;float:left; font-size:30px;font-family:Baskerville, "Palatino Linotype", Palatino, "Century Schoolbook L", "Times New Roman", "serif";z-index:1;height:500px;}
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− | .menuDiv a{text-decoration: none; transition: 0.2s all;
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− | -webkit-transition: 0.2s all;
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− | -moz-transition: 0.2s all;
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− | -o-transition: 0.2s all;}
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− | .menuDiv ul,.menuDiv li {list-style: none;padding:0px;float: left;}
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− | .menuDiv > ul > li > ul {position: absolute;display: none;}
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− | .menuDiv > ul > li > ul > li {float: none;}
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− | .menuDiv > ul > li:hover ul { display: block;}
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− | .menuDiv > ul > li > a {width:120px;margin-top:0px;line-height:50px;color: black;background-color:#f6f6f6;text-align: center;border-left: none;display: block;font-size:20px;letter-spacing:1px} | + | |
− | .menuDiv > ul > li:first-child > a { border-left-style:none;}
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− | .menuDiv > ul > li > a:hover {color:#0FC7B8}
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− | .menuDiv > ul > li > ul > li > a {width: 150px;font-size:16px;line-height:40px;color: black;
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− | background-color:#f6f6f6;text-align:center;border:none;display: block;margin-left:-60px;letter-spacing:1px}
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− | .menuDiv > ul > li > ul > li:first-child > a {border-top-style:none;}
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− | .menuDiv > ul > li > ul > li > a:hover {color:#0FC7B8;}
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− |
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− |
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− | .abstract{margin:0 10% auto 10% ;position:relative;padding-top:50px;}
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− | .abstract .title{position:relative;margin:0 auto auto 0;color:#660;font-family:Arial, Helvetica, sans-serif;font-size:30px}
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− | .abstract .content{top:10px;position:relative;letter-spacing:0.5px;font-family:Segoe, "Segoe UI", "DejaVu Sans", "Trebuchet MS", Verdana, "sans-serif";font-size:20px;word-break:break-all}
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| + | .abstract{margin:5em 20% auto 20%;position:relative} |
| + | .abstract .title{position:relative;margin:0 auto auto 0;color:#0172b4;font-family:Arial, Helvetica, sans-serif;font-size:30px} |
| + | .abstract .content{margin:0 auto;letter-spacing:0.02em;word-spacing:0.2em;font-family:Segoe, "Segoe UI", "DejaVu Sans", "Trebuchet MS", Verdana, "sans-serif";font-size:1.2em;word-wrap: break-word ;position:relative;text-indent:2em;text-align:left} |
| + | .video{text-align:center;z-index:2;positon:relative} |
| + | .foot{margin:10% auto auto auto} |
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− | .foot{width:100%;height:200px;background:#E9E9E9;position:relative;margin-top:40px;}
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| </style> | | </style> |
| </head> | | </head> |
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| <div class="bottom"> | | <div class="bottom"> |
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− | <div class="bar">
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− | <div calss="logo"><img src="https://static.igem.org/mediawiki/2017/3/3f/Igem.png" style="width:70px;height:auto;margin-left:30px;margin-top:5px;position: relative;display:inline-block;float:left"></div>
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− | <div calss="team"><img src="https://static.igem.org/mediawiki/2017/6/6d/SDU_CHINA.png" style="width:60px;height:auto;top:5px;right:30px;position:absolute;z-index:1;display:inline-block;float:right"></div>
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− | <div class="menuDiv">
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− | <ul>
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− | <li> <a href="https://2017.igem.org/Team:SDU_CHINA">Home</a></li>
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− | <li> <a href="https://2017.igem.org/Team:SDU_CHINA/project">Project</a>
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− | <ul>
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− | <li><a href="https://2017.igem.org/Team:SDU_CHINA/description">Description</a></li>
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− | <li><a href="https://2017.igem.org/Team:SDU_CHINA/design">Design</a></li>
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− | <li><a href="https://2017.igem.org/Team:SDU_CHINA/experiment">Experiment</a></li>
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− | <li><a href="https://2017.igem.org/Team:SDU_CHINA/results">Results</a></li>
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− | <li><a href="https://2017.igem.org/Team:SDU_CHINA/notebook">Notebook</a></li>
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− | </ul>
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− | </li>
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− | <li> <a href="https://2017.igem.org/Team:SDU_CHINA/model">Model</a></li>
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− | <li> <a href="https://2017.igem.org/Team:SDU_CHINA/interlab">Interlab</a></li>
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− | <li> <a href="https://2017.igem.org/Team:SDU_CHINA/parts">Parts</a>
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− | <ul>
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− | <li><a href="https://2017.igem.org/Team:SDU_CHINA/basic_parts">Basic parts</a></li>
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− | <li><a href="https://2017.igem.org/Team:SDU_CHINA/composite_parts">Composite parts</a></li>
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− | </ul>
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− | </li>
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− | <li> <a href="https://2017.igem.org/Team:SDU_CHINA/practice">Practice</a>
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− | <ul>
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− | <li><a href="https://2017.igem.org/Team:SDU_CHINA/public_education">Public education</a></li>
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− | <li><a href="https://2017.igem.org/Team:SDU_CHINA/society_activity">Society activity</a></li>
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− | </ul>
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− | </li>
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− | <li> <a href="https://2017.igem.org/Team:SDU_CHINA/awards">Awards</a></li>
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− | </ul>
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− | </div>
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− | </div>
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− |
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− | <div class="bg" > | + | <div class="bg" > |
− | <img src="https://static.igem.org/mediawiki/2017/4/4c/Bg.jpeg" style="width:100%;height:auto"> | + | <img src="https://static.igem.org/mediawiki/2017/4/4c/Bg.jpeg" style="width:100%;height:auto" style="width:100%;height:auto"> |
| </div> | | </div> |
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− | </div> | + | <div class="c"><img src="https://static.igem.org/mediawiki/2017/9/92/Abstract.jpeg" style="width:100%;height:auto"></div> |
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− | <div class="abstract" >
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− | <div class="title"><b>Abstract</b></div>
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− | <div class="content"><p>Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death among the world with low overall survival rate. In NSCLC, immunotherapy has been indicated
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− | as a potential therapy for treating in situ solid tumor. Previous research has indicated that tumor cells can express programmed death-1 ligand (PD-L1) to diminish T-cell effector functions and
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− | therefore to achieve immune escape. In our project, gene edition will be incorporated with immunotherapy to eradicate the immune escape occurred in NSCLC. By constructing plasmid with
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− | Crispr-Cas 9 system targeting the gene coding for PD-L1, the expression of PD-L1 will be inhibited to restore immune system supervision. To ensure the biosafety, another plasmid with
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− | Crsipr-Cas 9 system to cut off the housekeeping gene of two plasmids will be also constructed to suicide both plasmid when PD-L1 expression was not detectable. Better therapeutic effects of immunotherapy to conquer the NSCLC are hoped to be achieved.</p></div>
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− | </div>
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− | <br><br><br><br><br>
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− | <div>
| + | |
− | <div class="foot"></div>
| + | <div class="video" style="background:url('https://static.igem.org/mediawiki/2017/5/55/Bggg.jpeg');background-size:100%;padding-top:12em;height:480px;background-repeat:none"> |
| + | <video src="https://static.igem.org/mediawiki/2017/1/10/Video.mp4" width="48%" controls="controls"> |
| </div> | | </div> |
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| + | <div class="foot"><img src="https://static.igem.org/mediawiki/2017/0/04/Sponsor.jpeg" style="width:80%;height:auto;margin-top:-5em"></div> |
| + | <br><br> |
| + | <div class="footest"><img src="https://static.igem.org/mediawiki/2017/c/c0/Foot.jpeg" style="width:100%;height:auto"></div> |
| + | |
| + | </div> |
| </body> | | </body> |
| </html> | | </html> |