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Revision as of 10:51, 3 July 2017
Croc'n Cholera
Home
What
is
cholera?
The culprit:
Vibrio cholerae
Vibrio cholerae
Contaminates water and affects people in developing countries, war zones and natural disaster zones
2011
Last epidemy in an occidental country
4 millions
Number of cases per year
42
Number of concerned countries
→ Implemented solutions and their problems:
Too complicated to measure out
Too complicated to set up for big volumes
Too expensive
Our solution :
A synthetic biology innovative approach!
Fight V. cholerae with crocodile antimicrobial peptides!
What
is
our
project?
Our savior:
Sobki the crocodile
Sobki the crocodile
Can produce antimicrobial peptides that enables him to destroy V. cholerae in his natural habitat
Our system is made of two engineered microorganisms: Vibrio harveyi to detect V. cholerae and Pichia pastoris to produce crocodile AMPs. Thus one of our biggest challenge is to create an eukaryote-prokaryote communication system.
