Difference between revisions of "Team:IIT Delhi"

 
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<a href="index.html">iGEM IIT Delhi</a>
+
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     <div class="dropdown-content">
−
       <a href="#">Description</a>
+
       <a href="/Team:IIT_Delhi/Description">Overview</a>
−
       <a href="#">Results</a>
+
       <a href="/Team:IIT_Delhi/Design">Squarewave Generator</a>
−
      <a href="#">Proof of Concept</a>
+
 
−
       <a href="#">Basic Parts</a>
+
       <a href="/Team:IIT_Delhi/InterLab">Interlab</a>
−
      <a href="#">Composite Parts</a>
+
 
     </div>
 
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   </div>  
 
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−
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+
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−
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+
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−
       <a href="#">Overview</a>
+
       <a href="/Team:IIT_Delhi/Circuit_Design">Circuit design and construction</a>
−
       <a href="#">Logic Assessment</a>
+
       <a href="/Team:IIT_Delhi/Microfluidics">Microfluidics and Fluorescence</a>
−
       <a href="#">Signalling Tools</a>
+
       <a href="/Team:IIT_Delhi/Photobleaching">Photobleaching</a>
 +
      <a href="/Team:IIT_Delhi/Promoter">Promoter strength</a>
 +
                                                      <a href="/Team:IIT_Delhi/Oscillations">Oscillations</a>
 +
                                                     
 
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−
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 +
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      <a href="/Team:IIT_Delhi/Model">Overview</a>
 +
      <a href="/Team:IIT_Delhi/Write_Model">Writing a Model</a>
 +
                                                        <a href="/Team:IIT_Delhi/Deterministic_Model">Deterministic Model </a>
 +
                                                        <a href="/Team:IIT_Delhi/Stochastic_Model">Stochastic Model</a>
 +
                                                        <a href="/Team:IIT_Delhi/Bifurcation">Bifurcation and Squareness</a>
 +
                                                        <a href="/Team:IIT_Delhi/Resources">Resource sharing</a>
 +
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     <div class="dropdown-content-big">
−
       <a href="#">Human Practices</a>
+
       <a href="/Team:IIT_Delhi/HP/Silver">Human Practices</a>
−
       <a href="#">Integrated Practices</a>
+
       <a href="/Team:IIT_Delhi/HP/Gold_Integrated">Integrated Practices</a>
−
       <a href="#">Public Engagement</a>
+
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−
       <a href="#">Collaborations</a>
+
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 +
                                                        <a href="/Team:IIT_Delhi/Safety">Safety</a>
 
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                                                        <a href="/Team:IIT_Delhi/Collaborations">Overview</a>
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      <a href="/Team:IIT_Delhi/GMM_legislation">GMM Legislation</a>
 +
      <a href="/Team:IIT_Delhi/berlin">iGEM Berlin</a>
 +
      <a href="/Team:IIT_Delhi/mohali">Mentoring IISER Mohali</a>
 +
      <a href="/Team:IIT_Delhi/glasgow">iGEM Glasgow</a>
 +
             
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−
       <a href="#">Lab Records</a>
+
       <a href="/Team:IIT_Delhi/Notebook">Lab Records</a>
−
       <a href="#">Protocols</a>
+
       <a href="/Team:IIT_Delhi/protocol">Protocols</a>
−
       <a href="#">Recipes</a>
+
       <a href="/Team:IIT_Delhi/recipe">Recipes</a>
−
       <a href="#">Medal Criteria</a>
+
       <a href="/Team:IIT_Delhi/medal">Medal Criteria</a>
−
      <a href="#">Recipes</a>
+
     
 
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     <div class="dropdown-content">
 
     <div class="dropdown-content">
−
       <a href="team.html">The Team</a>
+
       <a href="/Team:IIT_Delhi/Team">The Team</a>
−
       <a href="#">Attributions</a>
+
 
 +
       <a href="/Team:IIT_Delhi/Attributions">Attributions</a>
 
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     </div>
 
   </div>   
 
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</section>
 
</section>
  
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<!-- Abstract -->
 
 
 
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    <h2 class="toppad">Abstract</h2>
 
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              <blockquote><p align = "left"  >Lack of digital responses in Synthetic Biology have inhibited the diverse potential that accompanies the digitization of biological circuits. This year we aim to develop synthetic modules for signal processing in biological systems, in the form of elements of specialized logic gates based on transcriptional regulation. We move from developing near digital logic gates with sharp responses, to more specialized collapsible and reconfigurable circuits which can perform various operations like developing square pulses. Further, to realize this aim of making a square wave generator, we engineered a five node repression based ring network to give digital oscillations. Quantitative computational modelling would be used to tailor the cellular environment and observe period, steepness, noise and amplitude variations. Our project poses to be an integral element in genetic networks intended to solve scientific challenges for years to come, ranging from making light sensitive frequency modulators and bacterial memory storage systems.</p>
 
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<h2 id="pfont">Lack of digital responses in Synthetic Biology have inhibited the diverse potential that accompanies the digitization of biological circuits. This year we developed synthetic modules for signal processing in biological systems, in the form of elements of specialized logic gates based on transcriptional regulation. We moved from computationally demonstrating near digital logic gates with sharp responses, to more specialized collapsible and reconfigurable circuits which can perform various operations like developing square pulses. Further, to realize the aim of making a square wave generator, we engineered a five node repression based ring network to give digital oscillations. Quantitative computational modelling was used to tailor the cellular environment and observe period, steepness, noise and amplitude variations. Our project poses to be an integral element in genetic networks intended to solve scientific challenges for years to come, ranging from making light sensitive frequency modulators and bacterial memory storage systems.</h2>
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<p ><b>E-mail:</b> iitd.igem@gmail.com<br>Undergraduate Laboratory<br>Department of Biotechnology and Biochemical Engineering, IIT Delhi
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<center> <p  style="text-align: center; color:white; font-size: 80%;">E-mail: iitd.igem@gmail.com<br>Undergraduate Laboratory<br>Department of Biotechnology and Biochemical Engineering, IIT Delhi</p></center>
 
 
 
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Latest revision as of 22:31, 1 November 2017

iGEM IIT Delhi

Overview Squarewave Generator Interlab
Circuit design and construction Microfluidics and Fluorescence Photobleaching Promoter strength Oscillations
Basic Parts Composite Parts Improved Parts Part Collection
Overview Writing a Model Deterministic Model Stochastic Model Bifurcation and Squareness Resource sharing
Human Practices Integrated Practices Public Engagement Collaborations Safety
Overview GMM Legislation iGEM Berlin Mentoring IISER Mohali iGEM Glasgow
Lab Records Protocols Recipes Medal Criteria
The Team Attributions

Abstract

                                                                                                                                                                                                                 

Lack of digital responses in Synthetic Biology have inhibited the diverse potential that accompanies the digitization of biological circuits. This year we developed synthetic modules for signal processing in biological systems, in the form of elements of specialized logic gates based on transcriptional regulation. We moved from computationally demonstrating near digital logic gates with sharp responses, to more specialized collapsible and reconfigurable circuits which can perform various operations like developing square pulses. Further, to realize the aim of making a square wave generator, we engineered a five node repression based ring network to give digital oscillations. Quantitative computational modelling was used to tailor the cellular environment and observe period, steepness, noise and amplitude variations. Our project poses to be an integral element in genetic networks intended to solve scientific challenges for years to come, ranging from making light sensitive frequency modulators and bacterial memory storage systems.



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Undergraduate Laboratory
Department of Biotechnology and Biochemical Engineering, IIT Delhi