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| − | <p>Tell us about your project, describe what moves you and why this is something important for your team.</p> | + | <p>This year we want to develop a pathogen-specific antibiotic to circumvent the possible establishment of resistance and side-effects during therapy. |
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| | + | We develop a novel sidechain for Clorobiocin via chemical synthesis and a newly designed enzyme expressed in Streptomyces. |
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| − | <h5>What should this page contain?</h5>
| + | This antibiotic will be used in toxicity assays in E. coli with novobiocin resistent gyrases, which could later be used in the treatment of MRSA. </p> |
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| − | <li> A clear and concise description of your project.</li>
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| − | <li>A detailed explanation of why your team chose to work on this particular project.</li>
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| − | <li>References and sources to document your research.</li>
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| − | <li>Use illustrations and other visual resources to explain your project.</li>
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| − | <h5>Advice on writing your Project Description</h5>
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| − | We encourage you to put up a lot of information and content on your wiki, but we also encourage you to include summaries as much as possible. If you think of the sections in your project description as the sections in a publication, you should try to be consist, accurate and unambiguous in your achievements.
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| − | Judges like to read your wiki and know exactly what you have achieved. This is how you should think about these sections; from the point of view of the judge evaluating you at the end of the year.
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| − | <h5>References</h5>
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| − | <p>iGEM teams are encouraged to record references you use during the course of your research. They should be posted somewhere on your wiki so that judges and other visitors can see how you thought about your project and what works inspired you.</p>
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| − | <h5>Inspiration</h5>
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| − | <p>See how other teams have described and presented their projects: </p>
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| − | <li><a href="https://2016.igem.org/Team:Imperial_College/Description">2016 Imperial College</a></li>
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| − | <li><a href="https://2016.igem.org/Team:Wageningen_UR/Description">2016 Wageningen UR</a></li>
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| − | <li><a href="https://2014.igem.org/Team:UC_Davis/Project_Overview"> 2014 UC Davis</a></li>
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| − | <li><a href="https://2014.igem.org/Team:SYSU-Software/Overview">2014 SYSU Software</a></li>
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Tuebingen
Description
This year we want to develop a pathogen-specific antibiotic to circumvent the possible establishment of resistance and side-effects during therapy.
We develop a novel sidechain for Clorobiocin via chemical synthesis and a newly designed enzyme expressed in Streptomyces.
This antibiotic will be used in toxicity assays in E. coli with novobiocin resistent gyrases, which could later be used in the treatment of MRSA.
