Difference between revisions of "Team:Toronto/Drylab"

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<p>Capturing the dynamics of construct developed in the Wet Lab to further characterize its behaviour with Ordinary Differential Equations (ODEs).</p>
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<p>Using Mathworks Simulink package, we ran multiple simulations to obtain a clear picture of how our system behaves. Then with R we leverage the data from Wet Lab to derive key parameters.</p>
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<p>We modeled LacILOV’s protein structure, which exposed undesirable interactions between the linker region and the functional domains. We then mutated the linker computationally to devise substitutions to improve LacILOV’s sensitivity to light.</p>
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Latest revision as of 20:32, 23 November 2017

Dry Lab

Ordinary Differential Equations

Capturing the dynamics of construct developed in the Wet Lab to further characterize its behaviour with Ordinary Differential Equations (ODEs).

Analysis

Using Mathworks Simulink package, we ran multiple simulations to obtain a clear picture of how our system behaves. Then with R we leverage the data from Wet Lab to derive key parameters.

Modelling

We modeled LacILOV’s protein structure, which exposed undesirable interactions between the linker region and the functional domains. We then mutated the linker computationally to devise substitutions to improve LacILOV’s sensitivity to light.

General Pages

Wet Lab

Dry Lab

Human Practices

iGEM Toronto