Difference between revisions of "Team:EpiphanyNYC"

 
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{{EpiphanyNYC]]
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<br><h4 style="text-transform:none;">The HD Resolution team at the 2017 Giant Jamboree</h4><br>
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<img src="https://static.igem.org/mediawiki/2017/1/1d/Epiphany-Jamboree-3.jpg" width=203px style="vertical-align: bottom;">&nbsp;
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<img src="https://static.igem.org/mediawiki/2017/0/0f/Epiphany-Jamboree-2.jpg" width=360px style="vertical-align: bottom;">
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<img src="https://static.igem.org/mediawiki/2017/1/15/Epiphany-Jamboree-1.jpg" width=360px>&nbsp;
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<img src="https://static.igem.org/mediawiki/2017/c/c1/Epiphany-Jamboree-4.jpg" width=360px>&nbsp;
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<div class="content_wrap"><div class="content"><article class="itemscope post_item post_item_single post_featured_center post_format_standard post-879 page type-page status-publish hentry" itemscope itemtype="http://schema.org/Article"><section class="post_content" itemprop="articleBody"><div class="vc_row wpb_row vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner "><div class="wpb_wrapper"><div class="sc_section"><div class="sc_section_inner"><figure id="brain" class="sc_image  sc_image_shape_square"></figure></div></div>
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<p><span style="font-weight: 400;">Huntington’s Disease (HD) is a genetic disorder that results in the breakdown of nerve cells in the brain. Although the disease affects the whole brain, the basal ganglia, which plays a critical role in motor functions and behavior, is most severely affected. Thus, symptoms of HD include involuntary movements, personality changes, and cognitive problems. Over time, the effects of HD is extremely debilitating, eventually rendering a patient unable to speak, walk, or even reason.</span></p>
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<h1 class="sc_title sc_title_regular sc_align_left" style="text-align:left;">WHY</h1>
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<p><span style="font-weight: 400;">HD is a result of a specific mutation in the huntingtin (HTT) gene, which results in a faulty production of the HTT protein, mHTT. The mutation is a trinucleotide repeat of the codon CAG, where 40 or more will lead to the expression of HD. </span></p>
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<h1 class="sc_title sc_title_regular sc_align_left" style="text-align:left;">WHO</h1>
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<p><span style="font-weight: 400;">The most common form of HD is adult-onset, affecting people between their 30s and 40s. Many people form families and have children by the time they are diagnosed with HD, which automatically gives their children a 50% chance of inheriting the disease. HD affects about 1 in every 10,000 people worldwide. </span></p>
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<h1 style="text-align:left;">HOW</h1>
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<p><span style="font-weight: 400;">Our goal is to develop a cure to Huntington’s Disease by employing RNA strand displacement technology to target erroneous mRNA within the affected cells and replace it with the corrected RNA strand for proper protein synthesis.</span></p>
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<img src="https://hdresolutionigem.com/wp-content/uploads/2017/07/Final-logo-e1501223428664.jpg" style="width:100px;">&nbsp;<h3>HD RESOLUTION</h3>
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<p> hdresolutionigem@gmail.com | Phone: (347) 709-6167 </p>
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<link rel="EditURI" type="application/rsd+xml" title="RSD" href="https://hdresolutionigem.com/xmlrpc.php?rsd" />
+
−
<link rel="wlwmanifest" type="application/wlwmanifest+xml" href="https://hdresolutionigem.com/wp-includes/wlwmanifest.xml" />
+
−
<meta name="generator" content="WordPress 4.8.1" />
+
−
<link rel="canonical" href="https://hdresolutionigem.com/" />
+
−
<link rel='shortlink' href='https://wp.me/P8T5BB-eb' />
+
−
<link rel="alternate" type="application/json+oembed" href="https://hdresolutionigem.com/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fhdresolutionigem.com%2F" />
+
−
<link rel="alternate" type="text/xml+oembed" href="https://hdresolutionigem.com/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fhdresolutionigem.com%2F&#038;format=xml" />
+
−
<script type="text/javascript">
+
−
var ajaxRevslider;
+
−
+
−
jQuery(document).ready(function() {
+
−
// CUSTOM AJAX CONTENT LOADING FUNCTION
+
−
ajaxRevslider = function(obj) {
+
−
+
−
// obj.type : Post Type
+
−
// obj.id : ID of Content to Load
+
−
// obj.aspectratio : The Aspect Ratio of the Container / Media
+
−
// obj.selector : The Container Selector where the Content of Ajax will be injected. It is done via the Essential Grid on Return of Content
+
−
+
−
var content = "";
+
  
−
data = {};
+
#bodyContent h1,
−
+
#bodyContent h2,
−
data.action = 'revslider_ajax_call_front';
+
#bodyContent h3,
−
data.client_action = 'get_slider_html';
+
#bodyContent h4,
−
data.token = '17feb8ef89';
+
#bodyContent h5 {
−
data.type = obj.type;
+
  margin-bottom: 0px;
−
data.id = obj.id;
+
}
−
data.aspectratio = obj.aspectratio;
+
−
+
−
// SYNC AJAX REQUEST
+
−
jQuery.ajax({
+
−
type:"post",
+
−
url:"https://hdresolutionigem.com/wp-admin/admin-ajax.php",
+
−
dataType: 'json',
+
−
data:data,
+
−
async:false,
+
−
success: function(ret, textStatus, XMLHttpRequest) {
+
−
if(ret.success == true)
+
−
content = ret.data;
+
−
},
+
−
error: function(e) {
+
−
console.log(e);
+
−
}
+
−
});
+
−
+
−
// FIRST RETURN THE CONTENT WHEN IT IS LOADED !!
+
−
return content;
+
−
};
+
−
+
−
// CUSTOM AJAX FUNCTION TO REMOVE THE SLIDER
+
−
var ajaxRemoveRevslider = function(obj) {
+
−
return jQuery(obj.selector+" .rev_slider").revkill();
+
−
};
+
  
−
// EXTEND THE AJAX CONTENT LOADING TYPES WITH TYPE AND FUNCTION
+
#bodyContent {
−
var extendessential = setInterval(function() {
+
   padding-right: 0px;
−
if (jQuery.fn.tpessential != undefined) {
+
}
−
clearInterval(extendessential);
+
−
if(typeof(jQuery.fn.tpessential.defaults) !== 'undefined') {
+
−
jQuery.fn.tpessential.defaults.ajaxTypes.push({type:"revslider",func:ajaxRevslider,killfunc:ajaxRemoveRevslider,openAnimationSpeed:0.3});    
+
−
// type: Name of the Post to load via Ajax into the Essential Grid Ajax Container
+
−
// func: the Function Name which is Called once the Item with the Post Type has been clicked
+
−
// killfunc: function to kill in case the Ajax Window going to be removed (before Remove function !
+
−
// openAnimationSpeed: how quick the Ajax Content window should be animated (default is 0.3)
+
−
}
+
−
}
+
−
},30);
+
−
});
+
−
</script>
+
−
+
−
<link rel='dns-prefetch' href='//v0.wordpress.com'>
+
−
<link rel='dns-prefetch' href='//i0.wp.com'>
+
−
<link rel='dns-prefetch' href='//i1.wp.com'>
+
−
<link rel='dns-prefetch' href='//i2.wp.com'>
+
−
<style type='text/css'>img#wpstats{display:none}</style><meta name="generator" content="Powered by Visual Composer - drag and drop page builder for WordPress."/>
+
−
<!--[if lte IE 9]><link rel="stylesheet" type="text/css" href="https://hdresolutionigem.com/wp-content/plugins/js_composer/assets/css/vc_lte_ie9.min.css" media="screen"><![endif]--><!--[if IE  8]><link rel="stylesheet" type="text/css" href="https://hdresolutionigem.com/wp-content/plugins/js_composer/assets/css/vc-ie8.min.css" media="screen"><![endif]--><style type="text/css" id="custom-background-css">
+
−
body.custom-background { background-color: #ffffff; }
+
−
</style>
+
−
<meta name="generator" content="Powered by Slider Revolution 5.2.6 - responsive, Mobile-Friendly Slider Plugin for WordPress with comfortable drag and drop interface." />
+
  
−
<!-- Jetpack Open Graph Tags -->
+
#globalWrapper {
−
<meta property="og:type" content="website" />
+
  font-size: 100%;
−
<meta property="og:title" content="HD Resolution" />
+
  padding: 0px;
−
<meta property="og:url" content="https://hdresolutionigem.com/" />
+
  margin: -10px -20px -20px -20px;
−
<meta property="og:site_name" content="HD Resolution" />
+
}
−
<meta property="og:image" content="https://s0.wp.com/i/blank.jpg" />
+
−
<meta property="og:locale" content="en_US" />
+
−
<meta name="twitter:card" content="summary" />
+
−
<meta name="twitter:description" content="Visit the post for more." />
+
−
<style type="text/css" id="wp-custom-css">
+
−
/*
+
−
You can add your own CSS here.
+
  
−
Click the help icon above to learn more.
+
.navbar-collapse {
−
*/
+
  padding-left: 0px;
 +
}
  
−
/*HEADER=========================*/
+
#banner {
−
/*======DESKTOP==================*/
+
  margin-top: 50px;
−
.content_wrap {
+
−
margin: auto !important;
+
 
}
 
}
  
−
.contact_logo {
+
#sideMenu {
−
height: 100% !important;
+
  margin-top: 10px;
 
}
 
}
  
−
.logo {
+
.dropdown-menu li:hover .sub-menu {
−
margin: 0 !important; /* for computers */
+
  visibility: visible;
−
padding: 0 !important; /* for mobile */
+
−
height: 100% !important;
+
 
}
 
}
  
−
.logo a {
+
.dropdown:hover .dropdown-menu {
−
display: flex;
+
  display: block;
−
flex-flow: row nowrap;
+
−
justify-content: center; /* if content ever wrapped centered */
+
−
align-items: center; /* vertical alignment */
+
−
height: 100% !important;
+
 
}
 
}
  
−
.logo_main {
+
.navbar-nav .dropdown-menu,
−
margin: 5px !important;
+
.navbar .dropdown-menu {
−
max-height: 100px !important;
+
  margin-top: 0;
−
height: 90% !important;
+
 
}
 
}
  
−
.top_panel_fixed .top_panel_wrap .content_wrap .contact_logo .logo {  
+
 
−
margin: 0 !important;  
+
/********************************* CONTENT OF THE PAGE ********************************/
 +
 
 +
 
 +
/* Wrapper for the content */
 +
 
 +
.content_wrapper {
 +
  width: 97%;
 +
  margin-left: 150px;
 +
  padding: 0px;
 +
  float: left;
 +
  background-color: white;
 
}
 
}
  
−
.logo_fixed {
 
−
margin: 5px !important;
 
−
max-height: none !important;
 
−
height: 90% !important;
 
−
}
 
−
/*======MOBILE===================*/
 
−
</style>
 
−
<noscript><style type="text/css"> .wpb_animate_when_almost_visible { opacity: 1; }</style></noscript></head>
 
  
−
<body class="home page-template-default page page-id-879 custom-background albertino_body body_style_wide body_filled theme_skin_default article_style_stretch layout_single-standard template_single-standard scheme_original top_panel_show top_panel_above sidebar_hide sidebar_outer_hide wpb-js-composer js-comp-ver-4.12 vc_responsive">
+
/*LAYOUT */
−
<a id="toc_home" class="sc_anchor" title="Home" data-description="&lt;i&gt;Return to Home&lt;/i&gt; - &lt;br&gt;navigate to home page of the site" data-icon="icon-home" data-url="https://hdresolutionigem.com/" data-separator="yes"></a><a id="toc_top" class="sc_anchor" title="To Top" data-description="&lt;i&gt;Back to top&lt;/i&gt; - &lt;br&gt;scroll to top of the page" data-icon="icon-double-up" data-url="" data-separator="yes"></a>
+
 
−
+
.column {
−
+
  padding: 10px 0px;
−
+
  float: left;
−
<div class="body_wrap">
+
  background-color: white;
 +
}
 +
 
 +
.full_size {
 +
  width: 100%;
 +
}
 +
 
 +
.full_size img {
 +
  padding: 10px 15px;
 +
  width: 96.5%;
 +
}
 +
 
 +
.half_size {
 +
  width: 50%;
 +
}
 +
 
 +
.half_size img {
 +
  padding: 10px 15px;
 +
  width: 93%;
 +
}
 +
 
 +
.img:hover {
 +
  opacity: 1.0 !important;
 +
}
 +
 
 +
.clear {
 +
  clear: both;
 +
}
 +
 
 +
.highlight {
 +
  width: 90%;
 +
  margin: auto;
 +
  padding: 15px 5px;
 +
  background-color: #f2f2f2;
 +
}
 +
 
 +
.judges-will-not-evaluate {
 +
  border: 4px solid #72c9b6;
 +
  display: block;
 +
  margin: 5px 15px;
 +
  width: 95%;
 +
  font-weight: bold;
 +
}
 +
 
 +
 
 +
/*STYLING */
 +
 
 +
 
 +
/* styling for the titles */
 +
 
 +
.content_wrapper h1,
 +
.content_wrapper h2 {
 +
  padding: 5px 15px;
 +
  border-bottom: 0px;
 +
  color: #72c9b6;
 +
}
 +
 
 +
.content_wrapper h3,
 +
.content_wrapper h4,
 +
.content_wrapper h5,
 +
.content_wrapper h6 {
 +
  padding: 5px 15px;
 +
  border-bottom: 0px;
 +
  color: #000000;
 +
}
 +
 
 +
 
 +
/* font and text */
 +
 
 +
.content_wrapper p {
 +
  padding: 0px 15px;
 +
  font-size: 13px;
 +
  font-family: 'Roboto', sans-serif;
 +
}
 +
 
 +
 
 +
/* Links */
 +
 
 +
.content_wrapper a {
 +
  font-weight: bold;
 +
  text-decoration: underline;
 +
  text-decoration-color: #72c9b6;
 +
  color: #72c9b6;
 +
  -webkit-transition: all 0.4s ease;
 +
  -moz-transition: all 0.4s ease;
 +
  -ms-transition: all 0.4s ease;
 +
  -o-transition: all 0.4s ease;
 +
  transition: all 0.4s ease;
 +
}
 +
 
 +
 
 +
/* hover for the links */
 +
 
 +
.content_wrapper a:hover {
 +
  text-decoration: none;
 +
  color: #000000;
 +
}
 +
 
 +
 
 +
/* non numbered lists */
 +
 
 +
.content_wrapper ul {
 +
  padding: 0px 20px;
 +
  font-size: 13px;
 +
  font-family: 'Quicksand', sans-serif;
 +
}
 +
 
 +
 
 +
/* numbered lists */
 +
 
 +
.content_wrapper ol {
 +
  padding: 0px;
 +
  font-size: 13px;
 +
  font-family: 'Quicksand', sans-serif;
 +
}
 +
 
 +
 
 +
/* Table */
 +
 
 +
.content_wrapper table {
 +
  width: 97%;
 +
  margin: 15px 10px;
 +
  border: 1px solid #d3d3d3;
 +
  border-collapse: collapse;
 +
}
 +
 
 +
 
 +
/* table cells */
 +
 
 +
.content_wrapper td {
 +
  padding: 10px;
 +
  vertical-align: text-top;
 +
  border: 1px solid #d3d3d3;
 +
  border-collapse: collapse;
 +
}
 +
 
 +
 
 +
/* table headers */
 +
 
 +
.content_wrapper th {
 +
  padding: 10px;
 +
  vertical-align: text-top;
 +
  border: 1px solid #d3d3d3;
 +
  border-collapse: collapse;
 +
  background-color: #f2f2f2;
 +
}
 +
 
 +
 
 +
/* Button class */
 +
 
 +
.button_click {
 +
  margin: 10px auto;
 +
  padding: 15px;
 +
  width: 12%;
 +
  text-align: center;
 +
  font-weight: bold;
 +
  background-color: #72c9b6;
 +
  cursor: pointer;
 +
  -webkit-transition: all 0.4s ease;
 +
  -moz-transition: all 0.4s ease;
 +
  -ms-transition: all 0.4s ease;
 +
  -o-transition: all 0.4s ease;
 +
  transition: all 0.4s ease;
 +
}
 +
 
 +
 
 +
/* button class on hover */
 +
 
 +
.button_click:hover {
 +
  background-color: #000000;
 +
  color: #72c9b6;
 +
}
 +
 
 +
.top-pad {
 +
  padding: 35px;
 +
}
 +
 
 +
 
 +
/********************************* RESPONSIVE STYLING ********************************/
 +
 
 +
 
 +
/* IF THE SCREEN IS LESS THAN 1000PX */
 +
 
 +
@media only screen and (max-width: 1000px) {
 +
  #content {
 +
    width: 100%;
 +
  }
 +
  .menu_wrapper {
 +
    width: 15%;
 +
  }
 +
  .content_wrapper {
 +
    margin-left: 15%;
 +
  }
 +
  .menu_item {
 +
    display: block;
 +
  }
 +
  .icon {
 +
    display: none;
 +
  }
 +
  .highlight {
 +
    padding: 10px 0px;
 +
  }
 +
}
 +
 
 +
 
 +
/* IF THE SCREEN IS LESS THAN 680PX */
 +
 
 +
@media only screen and (max-width: 680px) {
 +
  .collapsable_menu_control {
 +
    display: block;
 +
  }
 +
  .menu_item {
 +
    display: none;
 +
  }
 +
  .menu_wrapper {
 +
    width: 100%;
 +
    height: 15%;
 +
    position: relative;
 +
  }
 +
  .content_wrapper {
 +
    width: 100%;
 +
    margin-left: 0px;
 +
  }
 +
  .column.half_size {
 +
    width: 100%;
 +
  }
 +
  .column img {
 +
    width: 100%;
 +
    padding: 5px 0px;
 +
  }
 +
  .icon {
 +
    display: block;
 +
  }
 +
  .highlight {
 +
    padding: 15px 5px;
 +
  }
 +
}
 +
 
 +
.navbar-header {
 +
  padding-left: 20px;
 +
}
 +
 
 +
</style>
 +
 
 +
<script>
 +
 
 +
// This is the jquery part of your template.  Try not modify any of this code since it makes your menu work.
 +
 
 +
$(document).ready(function() {
  
 +
$("#HQ_page").attr('id','');
 
 
−
<div class="page_wrap">
 
  
−
+
if ( wgPageName.substring( 0,  8) == "Template")  {  // if the page is a template it displays the full name in a single line
−
<div class="top_panel_fixed_wrap"></div>
+
$("#team_name").html( wgPageName );
 +
}
  
−
<header class="top_panel_wrap top_panel_style_6 scheme_original">
+
else if (  ( (wgPageName.match(/\//g) || []).length ) == 0 ) {  // if it is the home page , just print the team's name
−
<div class="top_panel_wrap_inner top_panel_inner_style_6 top_panel_position_above">
+
$("#team_name").html( wgPageName.substring( 5, wgPageName.length ) );
 +
}
  
−
<div class="top_panel_middle" >
+
else {
−
<div class="content_wrap">
+
// this adds the team's name as an h1
−
<div class="contact_logo">
+
$("#team_name").html( wgPageName.substring( 5 , wgPageName.indexOf("/") ) );
−
<div class="logo">
+
−
<a href="https://hdresolutionigem.com/"><img src="https://hdresolutionigem.com/wp-content/uploads/2017/07/Final-logo-e1501223428664.jpg" class="logo_main" alt="" width="999" height="999"><img src="https://hdresolutionigem.com/wp-content/uploads/2017/07/Final-logo-e1501223428664.jpg" class="logo_fixed" alt="" width="999" height="999"><div class="logo_text">HD Resolution</div></a>
+
−
</div>
+
−
</div>
+
−
<div class="menu_main_wrap">
+
−
<nav class="menu_main_nav_area">
+
−
<ul id="menu_main" class="menu_main_nav"><li id="menu-item-727" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-727"><a href="https://hdresolutionigem.com/team/">Team</a>
+
−
<ul  class="sub-menu">
+
−
<li id="menu-item-990" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-990"><a href="https://hdresolutionigem.com/team/">Team</a></li>
+
−
<li id="menu-item-1011" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-1011"><a href="https://hdresolutionigem.com/attributions-2/">Attributions</a></li>
+
−
<li id="menu-item-733" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-733"><a href="https://hdresolutionigem.com/collaborations/">Collaborations</a></li>
+
−
</ul>
+
−
</li>
+
−
<li id="menu-item-713" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-713"><a href="https://hdresolutionigem.com/project/">Project</a>
+
−
<ul class="sub-menu">
+
−
<li id="menu-item-992" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-992"><a href="https://hdresolutionigem.com/what-is-hd/">What is HD?</a></li>
+
−
<li id="menu-item-729" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-729"><a href="https://hdresolutionigem.com/the-problem/">Description</a></li>
+
−
<li id="menu-item-756" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-756"><a href="https://hdresolutionigem.com/design/">Design</a></li>
+
−
<li id="menu-item-757" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-757"><a href="https://hdresolutionigem.com/experiments/">Experiments</a></li>
+
−
<li id="menu-item-759" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-759"><a href="https://hdresolutionigem.com/interlab/">Interlab</a></li>
+
−
<li id="menu-item-761" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-761"><a href="https://hdresolutionigem.com/model/">Model</a></li>
+
−
<li id="menu-item-763" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-763"><a href="https://hdresolutionigem.com/demonstrate/">Demonstrate</a></li>
+
−
<li id="menu-item-760" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-760"><a href="https://hdresolutionigem.com/contribution/">Collaboration</a></li>
+
−
</ul>
+
−
</li>
+
−
<li id="menu-item-762" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-762"><a href="https://hdresolutionigem.com/results/">Results</a></li>
+
−
<li id="menu-item-758" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-758"><a href="https://hdresolutionigem.com/notebook/">Notebook</a></li>
+
−
<li id="menu-item-781" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-781"><a href="https://hdresolutionigem.com/collaborations/">Human Practices</a>
+
−
<ul  class="sub-menu">
+
−
<li id="menu-item-783" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-783"><a href="https://hdresolutionigem.com/attributions-2/">Human Practices</a></li>
+
−
<li id="menu-item-784" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-784"><a href="https://hdresolutionigem.com/demonstrate/">Integrated Practices</a></li>
+
−
<li id="menu-item-785" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-785"><a href="https://hdresolutionigem.com/attributions-2/">Public Engagement</a></li>
+
−
</ul>
+
−
</li>
+
−
</ul> </nav>
+
−
<div class="search_wrap search_style_regular search_state_closed search_ajax top_panel_icon ">
+
−
<div class="search_form_wrap">
+
−
<form role="search" method="get" class="search_form" action="https://hdresolutionigem.com/">
+
−
<button type="submit" class="search_submit icon-search-light" title="Open search"></button>
+
−
<input type="text" class="search_field" placeholder="Search" value="" name="s" />
+
−
</form>
+
−
</div>
+
−
<div class="search_results widget_area scheme_original"><a class="search_results_close icon-cancel"></a><div class="search_results_content"></div></div>
+
−
</div> </div>
+
−
</div>
+
−
</div>
+
  
−
</div>
+
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<div class="content_wrap"><div class="content"><article class="itemscope post_item post_item_single post_featured_center post_format_standard post-879 page type-page status-publish hentry" itemscope itemtype="http://schema.org/Article"><section class="post_content" itemprop="articleBody"><div class="vc_row wpb_row vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner "><div class="wpb_wrapper"><div class="sc_section"><div class="sc_section_inner"><figure id="brain" class="sc_image  sc_image_shape_square"><img src="https://i1.wp.com/hdresolutionigem.com/wp-content/uploads/2017/08/blah.gif?fit=1702%2C1087&#038;ssl=1" alt="" /></figure></div></div><div class="vc_empty_space"  style="height: 100px" ><span class="vc_empty_space_inner"></span></div>
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<p><span style="font-weight: 400;">Huntington’s Disease (HD) is a genetic disorder that results in the breakdown of nerve cells in the brain. Although the disease affects the whole brain, the basal ganglia, which plays a critical role in motor functions and behavior, is most severely affected. Thus, symptoms of HD include involuntary movements, personality changes, and cognitive problems. Over time, the effects of HD is extremely debilitating, eventually rendering a patient unable to speak, walk, or even reason.</span></p>
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<p><span style="font-weight: 400;">HD is a result of a specific mutation in the huntingtin (HTT) gene, which results in a faulty production of the HTT protein, mHTT. The mutation is a trinucleotide repeat of the codon CAG, where 40 or more will lead to the expression of HD. </span></p>
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</div><div class="column-1_3 sc_column_item sc_column_item_2 even"><figure id="neuron" class="sc_image  sc_image_shape_square"><img src="https://i1.wp.com/hdresolutionigem.com/wp-content/uploads/2017/07/1-e1501887255315.jpg?fit=771%2C1800&#038;ssl=1" alt="" /></figure></div><div class="column-1_3 sc_column_item sc_column_item_3 odd"><div class="vc_empty_space"  style="height: 300px" ><span class="vc_empty_space_inner"></span></div>
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<p><span style="font-weight: 400;">The most common form of HD is adult-onset, affecting people between their 30s and 40s. Many people form families and have children by the time they are diagnosed with HD, which automatically gives their children a 50% chance of inheriting the disease. HD affects about 1 in every 10,000 people worldwide. </span></p>
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<h1>HOW</h1>
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<p><span style="font-weight: 400;">Our goal is to develop a cure to Huntington’s Disease by employing RNA strand displacement technology to target erroneous mRNA within the affected cells and replace it with the corrected RNA strand for proper protein synthesis.</span></p>
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Latest revision as of 00:42, 24 November 2017


The HD Resolution team at the 2017 Giant Jamboree


   

   

WHAT

Huntington’s Disease (HD) is a genetic disorder that results in the breakdown of nerve cells in the brain. Although the disease affects the whole brain, the basal ganglia, which plays a critical role in motor functions and behavior, is most severely affected. Thus, symptoms of HD include involuntary movements, personality changes, and cognitive problems. Over time, the effects of HD is extremely debilitating, eventually rendering a patient unable to speak, walk, or even reason.

WHY

HD is a result of a specific mutation in the huntingtin (HTT) gene, which results in a faulty production of the HTT protein, mHTT. The mutation is a trinucleotide repeat of the codon CAG, where 40 or more will lead to the expression of HD.

WHO

The most common form of HD is adult-onset, affecting people between their 30s and 40s. Many people form families and have children by the time they are diagnosed with HD, which automatically gives their children a 50% chance of inheriting the disease. HD affects about 1 in every 10,000 people worldwide.

HOW

Our goal is to develop a cure to Huntington’s Disease by employing RNA strand displacement technology to target erroneous mRNA within the affected cells and replace it with the corrected RNA strand for proper protein synthesis.

Hunt
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Cerebral Palsy
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HD RESOLUTION

hdresolutionigem@gmail.com | Phone: (347) 709-6167