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| − | <link href="https://2016.igem.org/Team:Imperial_College/Resources/CSS:BootstrapStyling?action=raw&ctype=text/css" rel="stylesheet"> | + | <br><h4 style="text-transform:none;">The HD Resolution team at the 2017 Giant Jamboree</h4><br> |
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| − | <h1> HD Resolution | iGEM Page </h1>
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| | <div class="content_wrap"><div class="content"><article class="itemscope post_item post_item_single post_featured_center post_format_standard post-879 page type-page status-publish hentry" itemscope itemtype="http://schema.org/Article"><section class="post_content" itemprop="articleBody"><div class="vc_row wpb_row vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner "><div class="wpb_wrapper"><div class="sc_section"><div class="sc_section_inner"><figure id="brain" class="sc_image sc_image_shape_square"></figure></div></div> | | <div class="content_wrap"><div class="content"><article class="itemscope post_item post_item_single post_featured_center post_format_standard post-879 page type-page status-publish hentry" itemscope itemtype="http://schema.org/Article"><section class="post_content" itemprop="articleBody"><div class="vc_row wpb_row vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner "><div class="wpb_wrapper"><div class="sc_section"><div class="sc_section_inner"><figure id="brain" class="sc_image sc_image_shape_square"></figure></div></div> |
| | </div></div></div></div><div class="vc_row wpb_row vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner "><div class="wpb_wrapper"><div class="sc_content content_wrap"><div class="columns_wrap sc_columns columns_fluid no_margins sc_columns_count_3"><div class="column-1_3 sc_column_item sc_column_item_1 odd first"><h1 class="sc_title sc_title_regular sc_align_left" style="text-align:left;">WHAT</h1> | | </div></div></div></div><div class="vc_row wpb_row vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner "><div class="wpb_wrapper"><div class="sc_content content_wrap"><div class="columns_wrap sc_columns columns_fluid no_margins sc_columns_count_3"><div class="column-1_3 sc_column_item sc_column_item_1 odd first"><h1 class="sc_title sc_title_regular sc_align_left" style="text-align:left;">WHAT</h1> |
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| | <p><span style="font-weight: 400;">Huntington’s Disease (HD) is a genetic disorder that results in the breakdown of nerve cells in the brain. Although the disease affects the whole brain, the basal ganglia, which plays a critical role in motor functions and behavior, is most severely affected. Thus, symptoms of HD include involuntary movements, personality changes, and cognitive problems. Over time, the effects of HD is extremely debilitating, eventually rendering a patient unable to speak, walk, or even reason.</span></p> | | <p><span style="font-weight: 400;">Huntington’s Disease (HD) is a genetic disorder that results in the breakdown of nerve cells in the brain. Although the disease affects the whole brain, the basal ganglia, which plays a critical role in motor functions and behavior, is most severely affected. Thus, symptoms of HD include involuntary movements, personality changes, and cognitive problems. Over time, the effects of HD is extremely debilitating, eventually rendering a patient unable to speak, walk, or even reason.</span></p> |
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| − | <p><span style="font-weight: 400;">HD is a result of a specific mutation in the huntington (HTT) gene, which results in a faulty production of the HTT protein, mHTT. The mutation is a trinucleotide repeat of the codon CAG, where 40 or more will lead to the expression of HD. </span></p> | + | <p><span style="font-weight: 400;">HD is a result of a specific mutation in the huntingtin (HTT) gene, which results in a faulty production of the HTT protein, mHTT. The mutation is a trinucleotide repeat of the codon CAG, where 40 or more will lead to the expression of HD. </span></p> |
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| − | </div><div class="column-1_3 sc_column_item sc_column_item_2 even"><figure id="neuron" class="sc_image sc_image_shape_square"><img src="https://i1.wp.com/hdresolutionigem.com/wp-content/uploads/2017/07/1-e1501887255315.jpg?fit=771%2C1800&ssl=1" alt="" /></figure></div><div class="column-1_3 sc_column_item sc_column_item_3 odd"><div class="vc_empty_space"><span class="vc_empty_space_inner"></span></div> | + | </div><div class="column-1_3 sc_column_item sc_column_item_2 even"><figure id="neuron" class="sc_image sc_image_shape_square"><img src="https://i1.wp.com/hdresolutionigem.com/wp-content/uploads/2017/07/1-e1501887255315.jpg?fit=771%2C1800&ssl=1" alt=" " style="padding-right: 10px; padding-left: 10px;" /></figure></div><div class="column-1_3 sc_column_item sc_column_item_3 odd"><div class="vc_empty_space"><span class="vc_empty_space_inner"></span></div> |
| | <div class="vc_empty_space" style="height: 200px" ><span class="vc_empty_space_inner"></span></div> | | <div class="vc_empty_space" style="height: 200px" ><span class="vc_empty_space_inner"></span></div> |
| | <h1 class="sc_title sc_title_regular sc_align_left" style="text-align:left;">WHO</h1> | | <h1 class="sc_title sc_title_regular sc_align_left" style="text-align:left;">WHO</h1> |
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| | <div class="wpb_wrapper"> | | <div class="wpb_wrapper"> |
| − | <h1>HOW</h1> | + | <h1 style="text-align:left;">HOW</h1> |
| | <p><span style="font-weight: 400;">Our goal is to develop a cure to Huntington’s Disease by employing RNA strand displacement technology to target erroneous mRNA within the affected cells and replace it with the corrected RNA strand for proper protein synthesis.</span></p> | | <p><span style="font-weight: 400;">Our goal is to develop a cure to Huntington’s Disease by employing RNA strand displacement technology to target erroneous mRNA within the affected cells and replace it with the corrected RNA strand for proper protein synthesis.</span></p> |
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| | <img src="https://hdresolutionigem.com/wp-content/uploads/2017/07/Final-logo-e1501223428664.jpg" style="width:100px;"> <h3>HD RESOLUTION</h3> | | <img src="https://hdresolutionigem.com/wp-content/uploads/2017/07/Final-logo-e1501223428664.jpg" style="width:100px;"> <h3>HD RESOLUTION</h3> |
| | <p> hdresolutionigem@gmail.com | Phone: (347) 709-6167 </p> | | <p> hdresolutionigem@gmail.com | Phone: (347) 709-6167 </p> |
| | + | |
| | + | <a href="https://www.facebook.com/HDResolution/" target="_blank"><img src="https://static.igem.org/mediawiki/2017/b/b7/IconFacebook.png"></a> |
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| | + | <a href="https://www.gofundme.com/hd-resolution-igem-team" target="_blank"><img src="https://static.igem.org/mediawiki/2017/d/dc/IconFund.png"></a> |
| | + | <a href="http://instagram.com/hdr.igem" target="_blank"><img src="https://static.igem.org/mediawiki/2017/e/e2/IconInstagram.png"></a> |
| | + | <p> </p> |
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| | <a href="https://www.gofundme.com/hd-resolution-igem-team"><img src="https://www.pro-tier.com/wp-content/uploads/2016/07/Icon_Money.png" style="width:30px;"></a> | | <a href="https://www.gofundme.com/hd-resolution-igem-team"><img src="https://www.pro-tier.com/wp-content/uploads/2016/07/Icon_Money.png" style="width:30px;"></a> |
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| | .content_wrapper { | | .content_wrapper { |
| − | width: 85%; | + | width: 97%; |
| | margin-left: 150px; | | margin-left: 150px; |
| | padding: 0px; | | padding: 0px; |
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| | padding: 15px 5px; | | padding: 15px 5px; |
| | } | | } |
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