Difference between revisions of "Team:EpiphanyNYC"

 
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<p><img src="https://i1.wp.com/hdresolutionigem.com/wp-content/uploads/2017/08/blah.gif?zoom=2&fit=1702%2C1087&ssl=1"></p>
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<br><h4 style="text-transform:none;">The HD Resolution team at the 2017 Giant Jamboree</h4><br>
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<img src="https://static.igem.org/mediawiki/2017/1/1d/Epiphany-Jamboree-3.jpg" width=203px style="vertical-align: bottom;">&nbsp;
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<iframe src="https://www.youtube.com/embed/Q_HjzWskqrU" width=480px height=270px style="vertical-align: bottom;" frameborder="0" gesture="media" allowfullscreen></iframe>&nbsp;
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<img src="https://static.igem.org/mediawiki/2017/0/0f/Epiphany-Jamboree-2.jpg" width=360px style="vertical-align: bottom;">
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<img src="https://static.igem.org/mediawiki/2017/1/15/Epiphany-Jamboree-1.jpg" width=360px>&nbsp;
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<img src="https://static.igem.org/mediawiki/2017/c/c1/Epiphany-Jamboree-4.jpg" width=360px>&nbsp;
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<img src="https://static.igem.org/mediawiki/2017/8/8a/Epiphany-Bronze.jpg" width=360px>
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<div class="content_wrap"><div class="content"><article class="itemscope post_item post_item_single post_featured_center post_format_standard post-879 page type-page status-publish hentry" itemscope itemtype="http://schema.org/Article"><section class="post_content" itemprop="articleBody"><div class="vc_row wpb_row vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner "><div class="wpb_wrapper"><div class="sc_section"><div class="sc_section_inner"><figure id="brain" class="sc_image  sc_image_shape_square"></figure></div></div>
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</div></div></div></div><div class="vc_row wpb_row vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner "><div class="wpb_wrapper"><div class="sc_content content_wrap"><div class="columns_wrap sc_columns columns_fluid no_margins sc_columns_count_3"><div class="column-1_3 sc_column_item sc_column_item_1 odd first"><h1 class="sc_title sc_title_regular sc_align_left" style="text-align:left;">WHAT</h1>
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<p><span style="font-weight: 400;">Huntington’s Disease (HD) is a genetic disorder that results in the breakdown of nerve cells in the brain. Although the disease affects the whole brain, the basal ganglia, which plays a critical role in motor functions and behavior, is most severely affected. Thus, symptoms of HD include involuntary movements, personality changes, and cognitive problems. Over time, the effects of HD is extremely debilitating, eventually rendering a patient unable to speak, walk, or even reason.</span></p>
  
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<h1> Welcome to iGEM 2017! </h1>
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<p>Your team has been approved and you are ready to start the iGEM season! </p>
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<h1 class="sc_title sc_title_regular sc_align_left" style="text-align:left;">WHY</h1>
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<p><span style="font-weight: 400;">HD is a result of a specific mutation in the huntingtin (HTT) gene, which results in a faulty production of the HTT protein, mHTT. The mutation is a trinucleotide repeat of the codon CAG, where 40 or more will lead to the expression of HD. </span></p>
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</div><div class="column-1_3 sc_column_item sc_column_item_2 even"><figure id="neuron" class="sc_image  sc_image_shape_square"><img src="https://i1.wp.com/hdresolutionigem.com/wp-content/uploads/2017/07/1-e1501887255315.jpg?fit=771%2C1800&#038;ssl=1" alt="" style="padding-right: 10px; padding-left: 10px;" /></figure></div><div class="column-1_3 sc_column_item sc_column_item_3 odd"><div class="vc_empty_space"><span class="vc_empty_space_inner"></span></div>
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<h1 class="sc_title sc_title_regular sc_align_left" style="text-align:left;">WHO</h1>
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<p><span style="font-weight: 400;">The most common form of HD is adult-onset, affecting people between their 30s and 40s. Many people form families and have children by the time they are diagnosed with HD, which automatically gives their children a 50% chance of inheriting the disease. HD affects about 1 in every 10,000 people worldwide. </span></p>
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<h1 style="text-align:left;">HOW</h1>
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<p><span style="font-weight: 400;">Our goal is to develop a cure to Huntington’s Disease by employing RNA strand displacement technology to target erroneous mRNA within the affected cells and replace it with the corrected RNA strand for proper protein synthesis.</span></p>
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<a href="http://hdsa.org/" target="_blank" class="vc_single_image-wrapper  vc_box_border_grey"><img class="vc_single_image-img " src="https://i0.wp.com/hdresolutionigem.com/wp-content/uploads/2017/08/Hunt-300x90.png" width="300" height="90" alt="Hunt" title="Hunt" /></a>
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<a href="http://www.hdfoundation.org" target="_blank" class="vc_single_image-wrapper  vc_box_border_grey"><img class="vc_single_image-img " src="https://i2.wp.com/hdresolutionigem.com/wp-content/uploads/2017/07/1479399868147-200x90.png" width="200" height="90" alt="1479399868147" title="1479399868147" /></a>
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<a href="http://cparf.org" target="_blank" class="vc_single_image-wrapper  vc_box_border_grey"><img class="vc_single_image-img " src="https://i1.wp.com/hdresolutionigem.com/wp-content/uploads/2017/07/Cerebral-Palsy-200x90.png" width="200" height="90" alt="Cerebral Palsy" title="Cerebral Palsy" /></a>
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<a href="http://www.steptember.us" target="_blank" class="vc_single_image-wrapper  vc_box_border_grey"><img class="vc_single_image-img " src="https://i2.wp.com/hdresolutionigem.com/wp-content/uploads/2017/07/Screen-Shot-2017-09-06-at-6.37.28-PM-200x90.png" width="200" height="90" alt="Screen Shot 2017-09-06 at 6.37.28 PM" title="Screen Shot 2017-09-06 at 6.37.28 PM" /></a>
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<h5>Before you start: </h5>
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<img src="https://hdresolutionigem.com/wp-content/uploads/2017/07/Final-logo-e1501223428664.jpg" style="width:100px;">&nbsp;<h3>HD RESOLUTION</h3>
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<p> Please read the following pages:</p>
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<p> hdresolutionigem@gmail.com | Phone: (347) 709-6167 </p>
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<ul>
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<li>  <a href="https://2017.igem.org/Competition">Competition Hub</a> </li>
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<li> <a href="https://2017.igem.org/Competition/Deliverables/Wiki">Wiki Requirements page</a></li>
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<li> <a href="https://2017.igem.org/Resources/Template_Documentation">Template documentation</a></li>
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</ul>
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<a href="https://www.facebook.com/HDResolution/" target="_blank"><img src="https://static.igem.org/mediawiki/2017/b/b7/IconFacebook.png"></a>
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<div class="highlight">
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<a href="https://twitter.com/HDR_iGEM" target="_blank"><img src="https://static.igem.org/mediawiki/2017/5/52/IconTwitter.png"></a>
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<h5> Styling your wiki </h5>
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<a href="https://www.gofundme.com/hd-resolution-igem-team" target="_blank"><img src="https://static.igem.org/mediawiki/2017/d/dc/IconFund.png"></a>
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<p>You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.</p>
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<a href="http://instagram.com/hdr.igem" target="_blank"><img src="https://static.igem.org/mediawiki/2017/e/e2/IconInstagram.png"></a>
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<p>While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.</p>  
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<p>&nbsp;</p>
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<h5> Wiki template information </h5>
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<div class="sc_socials sc_socials_type_icons sc_socials_shape_round sc_socials_size_medium"><div class="sc_socials_item"><a href="https://twitter.com/HDR_iGEM" target="_blank" class="social_icons social_twitter"><span class="icon-twitter"></span></a></div><div class="sc_socials_item"><a href="https://www.facebook.com/HDResolution/" target="_blank" class="social_icons social_facebook"><span class="icon-facebook"></span></a></div><div class="sc_socials_item"><a href="https://www.gofundme.com/hd-resolution-igem-team" target="_blank" class="social_icons social_money-light"><span class="icon-money-light"></span></a></div><div class="sc_socials_item"><a href="http://instagram.com/hdr.igem" target="_blank" class="social_icons social_instagramm"><span class="icon-instagramm"></span></a></div></div> </div>
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<p>We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the <a href="https://2017.igem.org/Judging/Pages_for_Awards">Pages for awards</a> link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!</p>
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<a href="https://www.facebook.com/HDResolution/"><img src="https://cdn4.iconfinder.com/data/icons/social-media-icons-the-circle-set/48/facebook_circle-512.png" style="width:30px;"></a>
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<a href="https://www.gofundme.com/hd-resolution-igem-team"><img src="https://www.pro-tier.com/wp-content/uploads/2016/07/Icon_Money.png" style="width:30px;"></a>
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<p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p>
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<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
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<li>Make sure information is easy to find; nothing should be more than 3 clicks away.  </li>
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<li>Avoid using very small fonts and low contrast colors; information should be easy to read.  </li>
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<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="https://2017.igem.org/Calendar">iGEM 2017 calendar</a> </li>
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<li> <a href="https://2014.igem.org/Team:SDU-Denmark/"> 2014 SDU Denmark </a> </li>
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<li> <a href="https://2014.igem.org/Team:Aalto-Helsinki">2014 Aalto-Helsinki</a> </li>
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<li> <a href="https://2014.igem.org/Team:LMU-Munich">2014 LMU-Munich</a> </li>
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<li> <a href="https://2014.igem.org/Team:Michigan"> 2014 Michigan</a></li>
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<li> <a href="https://2014.igem.org/Team:ITESM-Guadalajara">2014 ITESM-Guadalajara </a></li>
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<li> <a href="https://2014.igem.org/Team:SCU-China"> 2014 SCU-China </a></li>
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When you upload, set the "Destination Filename" to <br><code>T--YourOfficialTeamName--NameOfFile.jpg</code>. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)<br><br>
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  background-color: #72c9b6;
 +
  cursor: pointer;
 +
  -webkit-transition: all 0.4s ease;
 +
  -moz-transition: all 0.4s ease;
 +
  -ms-transition: all 0.4s ease;
 +
  -o-transition: all 0.4s ease;
 +
  transition: all 0.4s ease;
 +
}
 +
 
 +
 
 +
/* button class on hover */
 +
 
 +
.button_click:hover {
 +
  background-color: #000000;
 +
  color: #72c9b6;
 +
}
 +
 
 +
.top-pad {
 +
  padding: 35px;
 +
}
 +
 
 +
 
 +
/********************************* RESPONSIVE STYLING ********************************/
 +
 
 +
 
 +
/* IF THE SCREEN IS LESS THAN 1000PX */
 +
 
 +
@media only screen and (max-width: 1000px) {
 +
  #content {
 +
    width: 100%;
 +
  }
 +
  .menu_wrapper {
 +
    width: 15%;
 +
  }
 +
  .content_wrapper {
 +
    margin-left: 15%;
 +
  }
 +
  .menu_item {
 +
    display: block;
 +
  }
 +
  .icon {
 +
    display: none;
 +
  }
 +
  .highlight {
 +
    padding: 10px 0px;
 +
  }
 +
}
 +
 
 +
 
 +
/* IF THE SCREEN IS LESS THAN 680PX */
 +
 
 +
@media only screen and (max-width: 680px) {
 +
  .collapsable_menu_control {
 +
    display: block;
 +
  }
 +
  .menu_item {
 +
    display: none;
 +
  }
 +
  .menu_wrapper {
 +
    width: 100%;
 +
    height: 15%;
 +
    position: relative;
 +
  }
 +
  .content_wrapper {
 +
    width: 100%;
 +
    margin-left: 0px;
 +
  }
 +
  .column.half_size {
 +
    width: 100%;
 +
  }
 +
  .column img {
 +
    width: 100%;
 +
    padding: 5px 0px;
 +
  }
 +
  .icon {
 +
    display: block;
 +
  }
 +
  .highlight {
 +
    padding: 15px 5px;
 +
  }
 +
}
 +
 
 +
.navbar-header {
 +
  padding-left: 20px;
 +
}
 +
 
 +
</style>
 +
 
 +
<script>
 +
 
 +
// This is the jquery part of your template.  Try not modify any of this code since it makes your menu work.
 +
 
 +
$(document).ready(function() {
 +
 
 +
$("#HQ_page").attr('id','');
 +
 +
 
 +
if ( wgPageName.substring( 0,  8) == "Template")  {  // if the page is a template it displays the full name in a single line
 +
$("#team_name").html( wgPageName );
 +
}
 +
 
 +
else if (  ( (wgPageName.match(/\//g) || []).length ) == 0 ) {  // if it is the home page , just print the team's name
 +
$("#team_name").html( wgPageName.substring( 5, wgPageName.length ) );
 +
}
 +
 
 +
else {
 +
// this adds the team's name as an h1
 +
$("#team_name").html( wgPageName.substring( 5 , wgPageName.indexOf("/")  ) );
 +
 
 +
// this adds the page's title as an h4
 +
$("#page_name").html (    ( wgPageName.substring( wgPageName.indexOf("/") + 1, wgPageName.length ) ).replace( /\/|_/g , " ")  );
 +
}
 +
 
 +
 
 +
 
 +
 
 +
$('#accordion').find('.menu_item').click(function(){
 +
 
 +
//Expand or collapse this panel
 +
submenu = $(this).find('.submenu');
 +
submenu.toggle();
 +
 
 +
icon = $(this).find('.icon');
 +
 
 +
if ( !$( submenu ).is(':visible') ) {
 +
icon.removeClass("less").addClass("plus");
 +
}
 +
else {
 +
icon.removeClass("plus").addClass("less");
 +
}
 +
 
 +
//Hide the other panels
 +
$(".submenu").not(submenu).hide();
 +
$(".icon").not(icon).removeClass("less").addClass("plus");
 +
});
 +
 
 +
 
 +
$(".collapsable_menu_control").click(function() {
 +
$(".menu_item").toggle();
 +
});
 +
 
 +
$( window ).resize(function() {
 +
$(".menu_item").show();
 +
});
 +
 
 +
 
 +
});
  
  
  
  
 +
</script>
 +
</head>
  
  
  
 +
</body>
 
</html>
 
</html>

Latest revision as of 00:42, 24 November 2017


The HD Resolution team at the 2017 Giant Jamboree


   

   

WHAT

Huntington’s Disease (HD) is a genetic disorder that results in the breakdown of nerve cells in the brain. Although the disease affects the whole brain, the basal ganglia, which plays a critical role in motor functions and behavior, is most severely affected. Thus, symptoms of HD include involuntary movements, personality changes, and cognitive problems. Over time, the effects of HD is extremely debilitating, eventually rendering a patient unable to speak, walk, or even reason.

WHY

HD is a result of a specific mutation in the huntingtin (HTT) gene, which results in a faulty production of the HTT protein, mHTT. The mutation is a trinucleotide repeat of the codon CAG, where 40 or more will lead to the expression of HD.

WHO

The most common form of HD is adult-onset, affecting people between their 30s and 40s. Many people form families and have children by the time they are diagnosed with HD, which automatically gives their children a 50% chance of inheriting the disease. HD affects about 1 in every 10,000 people worldwide.

HOW

Our goal is to develop a cure to Huntington’s Disease by employing RNA strand displacement technology to target erroneous mRNA within the affected cells and replace it with the corrected RNA strand for proper protein synthesis.

Hunt
1479399868147
Cerebral Palsy
Screen Shot 2017-09-06 at 6.37.28 PM
 

HD RESOLUTION

hdresolutionigem@gmail.com | Phone: (347) 709-6167