Difference between revisions of "Team:EpiphanyNYC"

 
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{{EpiphanyNYC}}
 
{{EpiphanyNYC}}
 
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<p><img src="https://i1.wp.com/hdresolutionigem.com/wp-content/uploads/2017/08/blah.gif?zoom=2&fit=1702%2C1087&ssl=1"></p>
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<div style="display: inline-block; width: 100%;"><center>
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<br><h4 style="text-transform:none;">The HD Resolution team at the 2017 Giant Jamboree</h4><br>
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<p style="white-space:nowrap;">
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<img src="https://static.igem.org/mediawiki/2017/1/1d/Epiphany-Jamboree-3.jpg" width=203px style="vertical-align: bottom;">&nbsp;
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<iframe src="https://www.youtube.com/embed/Q_HjzWskqrU" width=480px height=270px style="vertical-align: bottom;" frameborder="0" gesture="media" allowfullscreen></iframe>&nbsp;
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<img src="https://static.igem.org/mediawiki/2017/0/0f/Epiphany-Jamboree-2.jpg" width=360px style="vertical-align: bottom;">
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</p><p style="white-space:nowrap;">
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<img src="https://static.igem.org/mediawiki/2017/1/15/Epiphany-Jamboree-1.jpg" width=360px>&nbsp;
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<img src="https://static.igem.org/mediawiki/2017/c/c1/Epiphany-Jamboree-4.jpg" width=360px>&nbsp;
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<img src="https://static.igem.org/mediawiki/2017/8/8a/Epiphany-Bronze.jpg" width=360px>
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</p>
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<div class="content_wrap"><div class="content"><article class="itemscope post_item post_item_single post_featured_center post_format_standard post-879 page type-page status-publish hentry" itemscope itemtype="http://schema.org/Article"><section class="post_content" itemprop="articleBody"><div class="vc_row wpb_row vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner "><div class="wpb_wrapper"><div class="sc_section"><div class="sc_section_inner"><figure id="brain" class="sc_image sc_image_shape_square"></figure></div></div>
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</div></div></div></div><div class="vc_row wpb_row vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner "><div class="wpb_wrapper"><div class="sc_content content_wrap"><div class="columns_wrap sc_columns columns_fluid no_margins sc_columns_count_3"><div class="column-1_3 sc_column_item sc_column_item_1 odd first"><h1 class="sc_title sc_title_regular sc_align_left" style="text-align:left;">WHAT</h1>
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<p><span style="font-weight: 400;">Huntington’s Disease (HD) is a genetic disorder that results in the breakdown of nerve cells in the brain. Although the disease affects the whole brain, the basal ganglia, which plays a critical role in motor functions and behavior, is most severely affected. Thus, symptoms of HD include involuntary movements, personality changes, and cognitive problems. Over time, the effects of HD is extremely debilitating, eventually rendering a patient unable to speak, walk, or even reason.</span></p>
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<h1 class="sc_title sc_title_regular sc_align_left" style="text-align:left;">WHY</h1>
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<p><span style="font-weight: 400;">HD is a result of a specific mutation in the huntingtin (HTT) gene, which results in a faulty production of the HTT protein, mHTT. The mutation is a trinucleotide repeat of the codon CAG, where 40 or more will lead to the expression of HD. </span></p>
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</div><div class="column-1_3 sc_column_item sc_column_item_2 even"><figure id="neuron" class="sc_image  sc_image_shape_square"><img src="https://i1.wp.com/hdresolutionigem.com/wp-content/uploads/2017/07/1-e1501887255315.jpg?fit=771%2C1800&#038;ssl=1" alt="" style="padding-right: 10px; padding-left: 10px;" /></figure></div><div class="column-1_3 sc_column_item sc_column_item_3 odd"><div class="vc_empty_space"><span class="vc_empty_space_inner"></span></div>
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<h1 class="sc_title sc_title_regular sc_align_left" style="text-align:left;">WHO</h1>
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<p><span style="font-weight: 400;">The most common form of HD is adult-onset, affecting people between their 30s and 40s. Many people form families and have children by the time they are diagnosed with HD, which automatically gives their children a 50% chance of inheriting the disease. HD affects about 1 in every 10,000 people worldwide. </span></p>
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<h1 style="text-align:left;">HOW</h1>
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<p><span style="font-weight: 400;">Our goal is to develop a cure to Huntington’s Disease by employing RNA strand displacement technology to target erroneous mRNA within the affected cells and replace it with the corrected RNA strand for proper protein synthesis.</span></p>
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<center>
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<img src="https://hdresolutionigem.com/wp-content/uploads/2017/07/Final-logo-e1501223428664.jpg" style="width:100px;">&nbsp;<h3>HD RESOLUTION</h3>
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<p> hdresolutionigem@gmail.com | Phone: (347) 709-6167 </p>
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<p>&nbsp;</p>
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<p>Huntington’s Disease (HD) is a genetic disorder that results in the breakdown of nerve cells in the brain. Although the disease affects the whole brain, the basal ganglia, which plays a critical role in motor functions and behavior, is most severely affected. Thus, symptoms of HD include involuntary movements, personality changes, and cognitive problems. Over time, the effects of HD is extremely debilitating, eventually rendering a patient unable to speak, walk, or even reason.</p>
 
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<p>HD is a result of a specific mutation in the huntingtin (HTT) gene, which results in a faulty production of the HTT protein, mHTT. The mutation is a trinucleotide repeat of the codon CAG, where 40 or more will lead to the expression of HD.</p>
 
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<p>Our goal is to develop a cure to Huntington’s Disease by employing RNA strand displacement technology to target erroneous mRNA within the affected cells and replace it with the corrected RNA strand for proper protein synthesis.</p>
 
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<h3>HD RESOLUTION</h3>
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<p> hdresolutionigem@gmail.com | Phone: (347) 709-6167 </p>
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Latest revision as of 00:42, 24 November 2017


The HD Resolution team at the 2017 Giant Jamboree


   

   

WHAT

Huntington’s Disease (HD) is a genetic disorder that results in the breakdown of nerve cells in the brain. Although the disease affects the whole brain, the basal ganglia, which plays a critical role in motor functions and behavior, is most severely affected. Thus, symptoms of HD include involuntary movements, personality changes, and cognitive problems. Over time, the effects of HD is extremely debilitating, eventually rendering a patient unable to speak, walk, or even reason.

WHY

HD is a result of a specific mutation in the huntingtin (HTT) gene, which results in a faulty production of the HTT protein, mHTT. The mutation is a trinucleotide repeat of the codon CAG, where 40 or more will lead to the expression of HD.

WHO

The most common form of HD is adult-onset, affecting people between their 30s and 40s. Many people form families and have children by the time they are diagnosed with HD, which automatically gives their children a 50% chance of inheriting the disease. HD affects about 1 in every 10,000 people worldwide.

HOW

Our goal is to develop a cure to Huntington’s Disease by employing RNA strand displacement technology to target erroneous mRNA within the affected cells and replace it with the corrected RNA strand for proper protein synthesis.

Hunt
1479399868147
Cerebral Palsy
Screen Shot 2017-09-06 at 6.37.28 PM
 

HD RESOLUTION

hdresolutionigem@gmail.com | Phone: (347) 709-6167