Difference between revisions of "Team:Exeter"

 
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     <div class="row" id="achievements">
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        <h1 class="mx-auto">Achievements</h1>
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         <h1>Pili<sup>+</sup></h1>
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        <div class="card w-75 mx-auto m-3">
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         <h3>Modified cell surface pili as a new vogue for bacterial bioremediation</h3>
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         <img class="card-img-top w-75 mx-auto mt-3" src="https://static.igem.org/mediawiki/2017/e/ea/T--Exeter--Awards_logo.png" alt="Gold Medal">
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          Heavy metal ion pollutants have significant effects on local flora and fauna and their leaching has implications for human health. Current treatment methods are energetically costly and, in the case of lime dosing, environmentally detrimental. We aim to investigate <i>E. coli</i> type 1 pili adhesion mechanisms and repurpose the involved structures to bind heavy metal ions in water. Pili are hair-like structures found on bacteria that attach to cell surface mannose molecules, using their terminal pili protein, FimH. Our aim is to fuse a variety of metal binding proteins to the FimH protein by modification of the <i>fimH</i> gene. The modified bacteria will be contained in a fluidised media reactor filter system used in conjunction with a hydrocyclone to prevent GMO release. Our modular cloning strategy, allows us to develop a toolkit for a wide number of pili applications and further future developments.
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        <h4 class="card-title" style="text-align:center;">Best Environment Project <br> <small><span class="text-muted">Overgraduate</span></small></h4>
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        <img class="card-img-top w-75 mx-auto mt-3" src="https://static.igem.org/mediawiki/2017/c/cf/T--Exeter--Gold_Medal_Icon.png" alt="Gold Medal">
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        <h4 class="card-title" style="text-align:center;">Gold Medal</h4>
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        <img class="card-img-top w-75 mx-auto mt-3" src="https://static.igem.org/mediawiki/2017/e/ea/T--Exeter--Awards_logo.png" alt="Gold Medal">
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        <h4 class="card-title" style="text-align:center;">Best Applied Design <br> <small><span class="text-muted">Overgraduate</span></small></h4>
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             <div class="card-body">
 
             <div class="card-body">
 
               <h4 class="card-title">Learn about what we did this summer</h4>
 
               <h4 class="card-title">Learn about what we did this summer</h4>
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               <p class="card-text">During the summer we worked in the lab to produce modified type I pili using a suitable <i>E. coli</i> chassis. </p>
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               <p class="card-text">During the summer we worked in the lab to produce modified type I pili in a suitable <i>E. coli</i> chassis. </p>
 
               <a href="https://2017.igem.org/Team:Exeter/Description" class="btn btn-primary" id="findOutMore">Find out more</a>
 
               <a href="https://2017.igem.org/Team:Exeter/Description" class="btn btn-primary" id="findOutMore">Find out more</a>
 
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Latest revision as of 13:52, 29 November 2017

Achievements

Gold Medal

Best Environment Project
Overgraduate

Gold Medal

Gold Medal

Gold Medal

Best Applied Design
Overgraduate

Learn about what we did this summer

During the summer we worked in the lab to produce modified type I pili in a suitable E. coli chassis.

Find out more

Find out about our filter system

As part of our project we developed a prototype of a filter system that could potentially be employed by the water industry.

Find out more

Meet the people behind the project

We are a team of ten undergraduate students from the University of Exeter.

Find out more