Difference between revisions of "Team:BGIC-Union"

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<html>
 +
  <head>
 +
  <html>
 
   <head>
 
   <head>
 
     <meta charset="utf-8">
 
     <meta charset="utf-8">
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   <head>
 
   <head>
 +
 
 +
 
   <!-- Bootstrap core CSS -->
 
   <!-- Bootstrap core CSS -->
 
     <link href="https://2017.igem.org/Template:BGIC-Union/bootstrap-css?action=raw&amp;ctype=text/css" rel="stylesheet">
 
     <link href="https://2017.igem.org/Template:BGIC-Union/bootstrap-css?action=raw&amp;ctype=text/css" rel="stylesheet">
 +
 +
  <!-- carousel -->
 +
  <link href="https://2017.igem.org/Template:BGIC-Union/owlcarousel-css?action=raw&amp;ctype=text/css" rel="stylesheet">
 +
  <link href=" https://2017.igem.org/Template:BGIC-Union/fontawesomemin2-css?action=raw&amp;ctype=text/css" rel="stylesheet">
  
 
   <!-- main -->
 
   <!-- main -->
 
   <style type="text/css">
 
   <style type="text/css">
 
    
 
    
−
@import url(http://fonts.googleapis.com/css?family=Montserrat:400,700);
+
 
 
#top_title,#sideMenu { display: none !important; }
 
#top_title,#sideMenu { display: none !important; }
 
         #content {
 
         #content {
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         }
 
         }
  
−
 
+
#bodyContent
 +
{
 +
margin-top：0px !important;
 +
}
  
  
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−
+
.mainstyle
 +
{
 +
font-family: Comic Sans MS;
 +
}
 
html, body {
 
html, body {
−
     margin: 0 !important;
+
     margin: 0 ;
−
     padding: 0 !important;
+
     padding: 0 ;
 
}
 
}
 
body {
 
body {
−
   background-color: #FFe4e1;
+
   background-color: #ffa07a;
−
   font-family: 'Montserrat', sans-serif;
+
   margin-keft：150px
 
     font-weight: 400;
 
     font-weight: 400;
 
     font-size: 14px;
 
     font-size: 14px;
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/* Titles */
 
/* Titles */
−
h1, h2, h3, h4, h5, h6 {
+
h1, h2, h3, h4, h5, h6, p {
−
font-family: 'Montserrat', sans-serif;
+
font-family: Comic Sans MS;
 
     font-weight: 700;
 
     font-weight: 700;
 
     color: #333;
 
     color: #333;
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−
/* Paragraph &amp; Typographic */
+
 
 
p {
 
p {
 
     line-height: 28px;
 
     line-height: 28px;
 
     margin-bottom: 25px;
 
     margin-bottom: 25px;
−
     font-size: 16px;
+
     font-size: 13px;
 +
font-family: Comic Sans MS;
 
}
 
}
  
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     color: #20B2AA;
 
     color: #20B2AA;
 
     word-wrap: break-word;
 
     word-wrap: break-word;
−
 
+
font-size: 18px;
 
     -webkit-transition: color 0.1s ease-in, background 0.1s ease-in;
 
     -webkit-transition: color 0.1s ease-in, background 0.1s ease-in;
 
     -moz-transition: color 0.1s ease-in, background 0.1s ease-in;
 
     -moz-transition: color 0.1s ease-in, background 0.1s ease-in;
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.navbar-inverse {
 
.navbar-inverse {
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padding-bottom: 70px;
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padding-bottom: 30px;
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padding-top: 70px;
+
padding-top: 0;
 
}
 
}
  
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.navbar-inverse .navbar-nav > li > a {
 
.navbar-inverse .navbar-nav > li > a {
 
color: white;
 
color: white;
 +
 
}
 
}
 +
  
 
.navbar-inverse .navbar-nav > li > a:hover {
 
.navbar-inverse .navbar-nav > li > a:hover {
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.navbar-brand {
 
.navbar-brand {
 
font-weight: 700;
 
font-weight: 700;
−
font-size: 20px;
+
font-size: 40px;
 
letter-spacing: 2px;
 
letter-spacing: 2px;
 +
backgroud: white;
 
}
 
}
  
 
.navbar-inverse .navbar-brand {
 
.navbar-inverse .navbar-brand {
 
color: white;
 
color: white;
 +
background-color: #FFA07A;
 +
 
}
 
}
  
 
.navbar-inverse .navbar-toggle {
 
.navbar-inverse .navbar-toggle {
 
border-color: transparent;
 
border-color: transparent;
 +
font-size: 12px;
 
}
 
}
  
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#ww {
 
#ww {
−
padding-top: 70px;
+
padding-top: 0px;
 
padding-bottom: 70px;
 
padding-bottom: 70px;
 
background-color: #f2f2f2;
 
background-color: #f2f2f2;
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#footer {
 
−
background-color: #ADD8E6;
 
−
padding-top: 50px;
 
−
padding-bottom: 50px;
 
−
}
 
−
 
−
#footer p {
 
−
color: white;
 
−
}
 
−
 
−
#footer h4 {
 
−
color: white;
 
−
text-transform: uppercase;
 
−
padding-bottom: 20px;
 
−
}
 
−
 
−
 
−
/* +++++ Color Wraps / Blog Page +++++ */
 
−
 
−
#grey {
 
−
padding-top: 60px;
 
−
padding-bottom: 60px;
 
−
background-color: #f2f2f2;
 
−
}
 
−
 
−
#white {
 
−
padding-top: 60px;
 
−
padding-bottom: 60px;
 
−
background-color: #ffffff;
 
−
}
 
−
 
−
 
−
 
−
/* Blog Date*/
 
−
bd {
 
−
font-size: 12px;
 
−
text-transform: uppercase;
 
−
color: #d2d2d2;
 
−
font-weight: 700;
 
−
}
 
−
 
−
/* Blog Author*/
 
−
ba {
 
−
font-size: 12px;
 
−
text-transform: uppercase;
 
−
}
 
−
 
−
/* Blog Quote */
 
−
.bq {
 
−
font-size: 22px;
 
−
padding-top: 30px;
 
−
}
 
−
 
−
/* Blog Tags */
 
−
bt {
 
−
font-size: 12px;
 
−
}
 
  
 
/* ================== PORTFOLIO IMAGES HOVER EFFECT ================== */
 
/* ================== PORTFOLIO IMAGES HOVER EFFECT ================== */
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     position:relative;  
 
     position:relative;  
 
     overflow:hidden;  
 
     overflow:hidden;  
−
     background:transparent url(../img/loader.gif) no-repeat center;
+
     background:transparent url(https://static.igem.org/mediawiki/2017/f/fe/Bgic_loader.gif) no-repeat center;
 
}
 
}
  
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}
 
}
  
−
/* glyphicon Configuration */
 
  
−
.glyphicon {
 
−
font-size: 40px;
 
−
color: #1abc9c;
 
−
}
 
 
   </style>
 
   </style>
 +
 
 
   <!-- script -->
 
   <!-- script -->
 
   <script src="https://code.jquery.com/jquery-1.10.2.min.js"></script>
 
   <script src="https://code.jquery.com/jquery-1.10.2.min.js"></script>
 
    
 
    
 
   <script src="https://2017.igem.org/Template:BGIC-Union/newbootstrap-js?action=raw&amp;ctype=text/javascript"></script>
 
   <script src="https://2017.igem.org/Template:BGIC-Union/newbootstrap-js?action=raw&amp;ctype=text/javascript"></script>
 +
 
  <!-- hover    -->   
 
  <!-- hover    -->   
 
   <script src="https://2017.igem.org/Template:BGIC-Union/hovernew-js?action=raw&amp;ctype=text/javascript"></script>
 
   <script src="https://2017.igem.org/Template:BGIC-Union/hovernew-js?action=raw&amp;ctype=text/javascript"></script>
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   </head>
 
   </head>
  
−
  <body>
+
 
−
<div class="column_full_size">
+
<body>
 +
<div class="column_full_size top1">
 
<nav class="navbar navbar-inverse navbar-static-top" role="navigation">
 
<nav class="navbar navbar-inverse navbar-static-top" role="navigation">
 
     <div class="container-fluid">  
 
     <div class="container-fluid">  
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     <div>
 
     <div>
 
         <ul class="nav navbar-nav navbar-center">
 
         <ul class="nav navbar-nav navbar-center">
−
             <li class="active">  <a href="https://2017.igem.org/Team:BGIC-Union">HOME</a></li>
+
             <li class="active" >  <a href="https://2017.igem.org/Team:BGIC-Union"><b>HOME</b></a></li>
 
            
 
            
−
             <li class="dropdown">
+
              
−
                <a href="https://2017.igem.org/Team:BGIC-Union/Team" class="dropdown-toggle" data-toggle="dropdown">TEAM <b class="caret"></b> </a>
+
          <li> <a href="https://2017.igem.org/Team:BGIC-Union/Team">Team</a></li>
−
               
+
  <li class="dropdown">
 +
                            <a href="https://2017.igem.org/Team:BGIC-Union/Team" class="dropdown-toggle" data-toggle="dropdown"> <b class="caret"></b></a>
 
                 <ul class="dropdown-menu">
 
                 <ul class="dropdown-menu">
 
                     <li><a href="https://2017.igem.org/Team:BGIC-Union/Team">members</a></li>
 
                     <li><a href="https://2017.igem.org/Team:BGIC-Union/Team">members</a></li>
−
                                 <li><a href="https://2017.igem.org/Team:BGIC-Union/Team">collaborations</a></li>
+
                                 <li><a href="https://2017.igem.org/Team:BGIC-Union/Collaborations">collaborations</a></li>
−
<li><a href="https://2017.igem.org/Team:BGIC-Union/Team">sponsors</a></li>
+
−
<li><a href="https://2017.igem.org/Team:BGIC-Union/Team">attributions</a></li>
+
<li><a href="https://2017.igem.org/Team:BGIC-Union/Attributions">attributions</a></li>
 
                             </ul>
 
                             </ul>
 
             </li>
 
             </li>
 +
 +
                          <li> <a href="https://2017.igem.org/Team:BGIC-Union/Project">Project</a></li>
 +
 
<li class="dropdown ">
 
<li class="dropdown ">
−
                             <a href="https://2017.igem.org/Team:BGIC-Union/Project" class="dropdown-toggle" data-toggle="dropdown">RPOJECT <b class="caret"></b>
+
                             <a href="https://2017.igem.org/Team:BGIC-Union/Project" class="dropdown-toggle" data-toggle="dropdown"> <b class="caret"></b></a>
 
</a>
 
</a>
 
                             <ul class="dropdown-menu" >
 
                             <ul class="dropdown-menu" >
−
                                 <li><a href="https://2017.igem.org/Team:BGIC-Union/Project">problems</a></li>
+
                                 <li><a href="https://2017.igem.org/Team:BGIC-Union/Description">description</a></li>
−
<li><a href="https://2017.igem.org/Team:BGIC-Union/Project">solutions</a></li>
+
<li><a href="https://2017.igem.org/Team:BGIC-Union/Design">design</a></li>
−
<li><a href="https://2017.igem.org/Team:BGIC-Union/Project">our design</a></li>
+
<li><a href="https://2017.igem.org/Team:BGIC-Union/Results">results</a></li>
−
                                <li><a href="https://2017.igem.org/Team:BGIC-Union/Project">results</a></li>
+
                         
−
<li><a href="https://2017.igem.org/Team:BGIC-Union/Project">interlab</a></li>
+
<li><a href="https://2017.igem.org/Team:BGIC-Union/Demonstrate">demonstrate</a></li>
−
                                <li><a href="https://2017.igem.org/Team:BGIC-Union/Project">references</a></li>
+
                                <li><a href="https://2017.igem.org/Team:BGIC-Union/Improve">improve</a></li>
 +
<li><a href="https://2017.igem.org/Team:BGIC-Union/References">references</a></li>
 
                             </ul>
 
                             </ul>
 
                         </li>
 
                         </li>
−
                         <li class="dropdown ">
+
                       
−
                            <a href="https://2017.igem.org/Team:BGIC-Union/Notebook" class="dropdown-toggle" data-toggle="dropdown">NOTEBOOK <b class="caret"></b></a>
+
                        <li>  <a href="https://2017.igem.org/Team:BGIC-Union/Lab">Lab</a></li>
 +
                         <li class="dropdown ">   <a href="https://2017.igem.org/Team:BGIC-Union/Lab" class="dropdown-toggle" data-toggle="dropdown"> <b class="caret"></b></a>
 
                             <ul class="dropdown-menu" role="menu">
 
                             <ul class="dropdown-menu" role="menu">
−
                                 <li><a href="https://2017.igem.org/Team:BGIC-Union/Notebook">protocol</a></li>
+
                                 <li><a href="https://2017.igem.org/Team:BGIC-Union/Experiments">protocols</a></li>
−
                                 <li><a href="https://2017.igem.org/Team:BGIC-Union/Notebook">lab journal</a></li>
+
                                 <li><a href="https://2017.igem.org/Team:BGIC-Union/Notebook">notebook</a></li>
−
<li><a href="https://2017.igem.org/Team:BGIC-Union/Notebook">safety</a></li>
+
<li><a href="https://2017.igem.org/Team:BGIC-Union/InterLab">InterLab</a></li></ul>
−
                            </ul>
+
 
                         </li>
 
                         </li>
−
                        <li class="dropdown ">
+
                     
−
                             <a href="https://2017.igem.org/Team:BGIC-Union/Achievements" class="dropdown-toggle" data-toggle="dropdown">ACHIEVEMENTS <b class="caret"></b></a>
+
<li><a href="https://2017.igem.org/Team:BGIC-Union/Parts">Parts</a></li>
 +
                             <li class="dropdown "> <a href="https://2017.igem.org/Team:BGIC-Union/Parts" class="dropdown-toggle" data-toggle="dropdown"> <b class="caret"></b></a>
 +
 
                             <ul class="dropdown-menu" role="menu">
 
                             <ul class="dropdown-menu" role="menu">
−
                                <li><a href="https://2017.igem.org/Team:BGIC-Union/Achievements">parts</a></li>
+
                              <li><a href="https://2017.igem.org/Team:BGIC-Union/Basic_Parts">basic parts</a></li>
−
<li><a href="https://2017.igem.org/Team:BGIC-Union/Achievements">improvements</a></li>
+
<li><a href="https://2017.igem.org/Team:BGIC-Union/Composite_Parts">composite parts</a></li>
−
<li><a href="https://2017.igem.org/Team:BGIC-Union/Achievements">applications</a></li>
+
<li><a href="https://2017.igem.org/Team:BGIC-Union/Parts_Collection">parts collection</a></li>
−
<li><a href="https://2017.igem.org/Team:BGIC-Union/Achievements">provision</a></li>
+
 
 +
 
 
                             </ul>
 
                             </ul>
 
                         </li>
 
                         </li>
−
<li class="dropdown ">
+
−
                            <a href="https://2017.igem.org/Team:BGIC-Union/Practices&amp;Design" class="dropdown-toggle" data-toggle="dropdown">PRACTICES&amp;DESIGN <b class="caret"></b></a>
+
                      <li>    <a href="https://2017.igem.org/Team:BGIC-Union/Practices-Design">Practices-Design</a></li>
 +
                          <li class="dropdown "> <a href="https://2017.igem.org/Team:BGIC-Union/Practices-Design" class="dropdown-toggle" data-toggle="dropdown"> <b class="caret"></b></a>
 
                             <ul class="dropdown-menu" role="menu">
 
                             <ul class="dropdown-menu" role="menu">
−
                                 <li><a href="https://2017.igem.org/Team:BGIC-Union/Practices&amp;Design">communication</a></li>
+
                             
−
                                <li><a href="https://2017.igem.org/Team:BGIC-Union/Practices&amp;Design">meet-up</a></li>
+
                                 <li><a href="https://2017.igem.org/Team:BGIC-Union/HP/Silver">silver</a></li>
−
<li><a href="https://2017.igem.org/Team:BGIC-Union/Practices&amp;Design">public outreach</a></li>
+
<li><a href="https://2017.igem.org/Team:BGIC-Union/HP/Gold_Integrated">gold</a></li>
−
<li><a href="https://2017.igem.org/Team:BGIC-Union/Practices&amp;Design">marketing</a></li>
+
−
<li><a href="https://2017.igem.org/Team:BGIC-Union/Practices&amp;Design">sustainability</a></li>
+
<li><a href="https://2017.igem.org/Team:BGIC-Union/Engagement">public engagement</a></li>
−
<li><a href="https://2017.igem.org/Team:BGIC-Union/Practices&amp;Design">arts</a></li>
+
<li><a href="https://2017.igem.org/Team:BGIC-Union/Applied_Design">applied design</a></li>
 +
 
 +
<li><a href="https://2017.igem.org/Team:BGIC-Union/Entrepreneurship">entrepreneurship</a></li>
 
                             </ul>
 
                             </ul>
 
                         </li>
 
                         </li>
 
<li class="dropdown ">
 
<li class="dropdown ">
−
                             <a href="https://2017.igem.org/Team:BGIC-Union/Evaluation" class="dropdown-toggle" data-toggle="dropdown">Modeling </a>
+
                             <a href="https://2017.igem.org/Team:BGIC-Union/Model">Model </a>
 
                         </li>
 
                         </li>
 
<li class="dropdown ">
 
<li class="dropdown ">
−
                             <a href="https://2017.igem.org/Team:BGIC-Union/Evaluation" class="dropdown-toggle" data-toggle="dropdown">EVALUATION </a>
+
                             <a href="https://2017.igem.org/Team:BGIC-Union/Safety">Safety </a>
 +
                        </li>
 +
<li class="dropdown ">
 +
                            <a href="https://2017.igem.org/Team:BGIC-Union/Evaluation" >EVALUATION </a>
 
                         </li>
 
                         </li>
 
         </ul>
 
         </ul>
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     </div>
 
     </div>
 
</nav>
 
</nav>
−
 
+
 +
 +
 +
</div>
 +
 +
  <section >
 +
        <div class="carousel slide" id="carousel-example-generic" data-ride="carousel">
 +
         
 +
 
 +
          <div class="carousel-inner">
 +
          <div class="item active">
 +
          <div class="overlay-slide">
 +
          <img src="https://static.igem.org/mediawiki/2017/archive/8/89/20171021063547%21P3%21%21%21.jpg" width="1300px" class="img-responsive">
 +
          </div>
 +
          <div class="carousel-caption">
 +
              <div class="col-md-12 col-xs-12 text-center">
 +
                      <h1>dCasentry</h1>
 +
              <h3 class="animated2">a <b>dCas9-T7</b>coupled DNA sensor </h3>
 +
              <div class="line"></div>
 +
              <p class="animated3"></p>
 +
              </div>
 +
          </div>
 +
          </div>
 +
 
 +
               
 +
        </div>
 +
  </section>
 +
    <!--/ Slider end -->
 +
    <!--/ Slider end -->
 +
 
<!-- +++++ Welcome Section +++++ -->
 
<!-- +++++ Welcome Section +++++ -->
 
<div id="ww">
 
<div id="ww">
 
    <div class="container">
 
    <div class="container">
 
<div class="row">
 
<div class="row">
−
<div class="col-lg-8 col-lg-offset-2 centered ">
+
<div class="col-lg-8 col-lg-offset-2 ">
 
 
−
<div style="height:122px; width:150px; border-radius:50%; overflow:hidden;  text-align:center;">
+
<div style="height:122px; width:150px; border-radius:50%; overflow:hidden; ">
 
<img src="https://static.igem.org/mediawiki/2017/d/db/User.png" height="120px" width="150px">
 
<img src="https://static.igem.org/mediawiki/2017/d/db/User.png" height="120px" width="150px">
 
</div>
 
</div>
−
<h1>Hi, I am dCasentry,</h1>
+
</div><h1 class="center">Hi, I am dCasentry,</h1>
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<h2>a T7—dCas9 multi-output DNA sensor designed to detect ctDNA!</h2>
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<p>Cancer is a leading cause of death worldwide, accounting for 8.8 million deaths in 2015, and the most common causes of cancer death is lung cancer (1.69 million deaths).
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Nowadays, multiple lung cancer detection methods are developed, and I can be an assistant in liquid biopsy whose detection minimizes  trauma and pain. The tumor marker I detect is circulating tumor DNA (ctDNA), tumor-derived fragmented DNA in the bloodstream that is not associated with cells. It is released by the dying cells during the biological process of apotheosis and necrosis, or active release from viable tumor cells.
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<div>dCasentry: A guardian against Lung Cancer</br>
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Lung cancer is one of the deadliest malignant tumors in the world, with highest death rate in China. The most widely used lung cancer detection method nowadays remains biopsy, which may cause pain infection and bruising. However, the technic of liquid biopsy obviates this problem by detecting various factors including circulating tumor DNA (ctDNA) in the blood. ctDNA is a short strand of DNA released from tumor cells that can be deemed as the sign of cancer. Although traditional liquid biopsy avoids many side effects, it requires laboratory apparatus such as PCR instrument during detection. Also, some other ctDNA detection systems fail to overcome the difficulty of the extremely low concentration of ctDNA in the blood. To solve those problems, we developed a new liquid biopsy method using dCas9 protein with a much simple procedure while increase the signal with various kinds of output. We hope to adopt free-dried paper chip as our vector of detecting system to simplify its operation as well as storage. Finally, the product will be presented as a kit that contains all the items you needed for convenient machine-free detection.
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<p>I am an improved version of the paired dCas9 system designed by 2015 Peking university iGEM, composing of sgRNA, a pair of dCas9 protein and a split T7 RNA polymerase switch connected to each dCas9 protein via a linker. The sgRNA is designed to detect target genes and I will complete my task according to this order: First, the sgRNA will instruct each sgRNA-dCas9 complex to certain locus. Next, unlike Peking University, a T7 RNA polymerase rather than a luciferase is split apart and connected to dCas9 protein via a linker. I call them NT7-dCas9 and CT7-dCas9. Once two sgRNA are attached to the target sequence, two split parts will reunion and reassemble to form a complete RNA polymerase and start transcription consistently, which means even though the initial ctDNA concentration is low, the signal will continue to be magnified until it can be observed. Also, there is no limit on the content I can transcribed, that is, I am able to give out many kinds of signals, including GFP, RFP or LacZ. </p>
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<p>In this project my main goal is to detect the fusion gene <i>EML4-ALK</i>. Some of the cancer, including non small cell lung cancer (NSCLC), is caused by gene fusion. When two respective original genes fuse together, it produces the expression product of fusion gene, which induced the canceration of cells. EML4-ALK exists only in NSCLC patients’ blood which prevents false positive result during detection and there is a specific  targeted drug for this mutation which means patients can have precise treatment as soon as possible when the detection result is positive. My work is meaningful.</p>
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<i>Please, click <a href="https://2017.igem.org/Team:BGIC-Union/Project">  here </a> and know more about me as well as the product!</i> </div>
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<p>Finally, as a well-rounded and efficient lung cancer fusion gene detection sentry, I am proud to point out this important reason why you can trust me —I can carry out a simpler liquid biopsy process. Although the liquid biopsy avoid copliacation, common liquid biopsy required laboratory apparatus such as PCR instrument during the detection of ctDNA. In my work, my DNA device and proteins that needed for detection will mixed in a E.coli cell-free system and freeze-dried on a paper screening chip. You will be seeing me in a convenient kit that contains all tools you need for detection, including hemostix, a hand power centrifuge, NASBA reaction system and the paper screening chip.</p>
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<p>Please, click <a href="https://2017.igem.org/Team:BGIC-Union/Project">  here </a> and know more about me as well as the product!</p>
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<p>EXTRACT </p>
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<h4><a href="https://2017.igem.org/Team:BGIC-Union/Parts">Best Parts </a></h4>
 
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<p>CENTRIFUGE</p>
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<h4><a href="https://2017.igem.org/Team:BGIC-Union/Applied_Design">Applied Design</a></h4>
 
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<p>ctDNA AMPLIFICATION</p>
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<h4><a href="https://2017.igem.org/Team:BGIC-Union/Gold_Integrated">Integrated Human Practice</a></h4>
 
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<p>DETECTION</p>
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<h4><a href="https://2017.igem.org/Team:BGIC-Union/Engagement">Education & Public Engagement</a></h4>
 
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<p>TEST CHIP</p>
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    <p>F12 BGI-College，146 Beishan Road，Yantian District 518083
 
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                                    </br> Shenzhen，Guangdong Province, China，Asia
 
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                                </br>Phone:+86-755-36307888
 
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                                </br>Email: info@genomics.cn
 
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Latest revision as of 13:11, 2 December 2017

Team：BGIC-Union

Hi, I am dCasentry,

dCasentry: A guardian against Lung Cancer
Lung cancer is one of the deadliest malignant tumors in the world, with highest death rate in China. The most widely used lung cancer detection method nowadays remains biopsy, which may cause pain infection and bruising. However, the technic of liquid biopsy obviates this problem by detecting various factors including circulating tumor DNA (ctDNA) in the blood. ctDNA is a short strand of DNA released from tumor cells that can be deemed as the sign of cancer. Although traditional liquid biopsy avoids many side effects, it requires laboratory apparatus such as PCR instrument during detection. Also, some other ctDNA detection systems fail to overcome the difficulty of the extremely low concentration of ctDNA in the blood. To solve those problems, we developed a new liquid biopsy method using dCas9 protein with a much simple procedure while increase the signal with various kinds of output. We hope to adopt free-dried paper chip as our vector of detecting system to simplify its operation as well as storage. Finally, the product will be presented as a kit that contains all the items you needed for convenient machine-free detection.
Please, click here and know more about me as well as the product!

Best Parts

Applied Design

Integrated Human Practice

Education & Public Engagement

Entreprenuership

Model