Difference between revisions of "Team:BGIC-Union"

 
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Line 1: Line 1:
  
 
<html>
 
<html>
 +
  <head>
 +
  <html>
 
   <head>
 
   <head>
 
     <meta charset="utf-8">
 
     <meta charset="utf-8">
Line 14: Line 16:
 
   <!-- Bootstrap core CSS -->
 
   <!-- Bootstrap core CSS -->
 
     <link href="https://2017.igem.org/Template:BGIC-Union/bootstrap-css?action=raw&amp;ctype=text/css" rel="stylesheet">
 
     <link href="https://2017.igem.org/Template:BGIC-Union/bootstrap-css?action=raw&amp;ctype=text/css" rel="stylesheet">
−
<!-- animate -->
+
 
−
<link href="https://2017.igem.org/Template:BGIC-Union/animate-css?action=raw&amp;ctype=text/css" rel="stylesheet">
+
 
   <!-- carousel -->
 
   <!-- carousel -->
 
   <link href="https://2017.igem.org/Template:BGIC-Union/owlcarousel-css?action=raw&amp;ctype=text/css" rel="stylesheet">
 
   <link href="https://2017.igem.org/Template:BGIC-Union/owlcarousel-css?action=raw&amp;ctype=text/css" rel="stylesheet">
 
   <link href=" https://2017.igem.org/Template:BGIC-Union/fontawesomemin2-css?action=raw&amp;ctype=text/css" rel="stylesheet">
 
   <link href=" https://2017.igem.org/Template:BGIC-Union/fontawesomemin2-css?action=raw&amp;ctype=text/css" rel="stylesheet">
  
−
<!-- main -->
+
  <!-- main -->
 
   <style type="text/css">
 
   <style type="text/css">
 
    
 
    
−
@import url(http://fonts.googleapis.com/css?family=Montserrat:400,700);
+
 
 
#top_title,#sideMenu { display: none !important; }
 
#top_title,#sideMenu { display: none !important; }
 
         #content {
 
         #content {
Line 32: Line 33:
 
         }
 
         }
  
−
 
+
#bodyContent
 +
{
 +
margin-top：0px !important;
 +
}
  
  
Line 40: Line 44:
  
  
−
+
.mainstyle
 +
{
 +
font-family: Comic Sans MS;
 +
}
 
html, body {
 
html, body {
−
     margin: 0 !important;
+
     margin: 0 ;
−
     padding: 0 !important;
+
     padding: 0 ;
−
 
+
 
}
 
}
 
body {
 
body {
−
   background-color: #FFe4e1;
+
   background-color: #ffa07a;
−
   font-family: 'Montserrat', sans-serif;
+
   margin-keft：150px
 
     font-weight: 400;
 
     font-weight: 400;
−
line-height: 25px;
+
     font-size: 14px;
−
     font-size: 17px;
+
 
     color: #555;
 
     color: #555;
−
 
+
     ；
−
      
+
 
     -webkit-font-smoothing: antialiased;
 
     -webkit-font-smoothing: antialiased;
 
     -webkit-overflow-scrolling: touch;
 
     -webkit-overflow-scrolling: touch;
Line 60: Line 64:
  
 
/* Titles */
 
/* Titles */
−
h1, h2, h3, h4, h5, h6,p {
+
h1, h2, h3, h4, h5, h6, p {
−
font-family: 'Montserrat', sans-serif;
+
font-family: Comic Sans MS;
−
     font-weight: 600;
+
     font-weight: 700;
 
     color: #333;
 
     color: #333;
−
line-height:30pt;
 
 
}
 
}
  
Line 70: Line 73:
 
font-size: 35px;
 
font-size: 35px;
 
margin-top: 30px;
 
margin-top: 30px;
−
margin-bottom: 50px;
+
margin-bottom: 30px;
 
}
 
}
  
  
  
−
/* Paragraph  Typographic */
+
 
 
p {
 
p {
−
     line-height: 50px;
+
     line-height: 28px;
−
     margin-bottom: 35px;
+
     margin-bottom: 25px;
−
     font-size: 16px;
+
     font-size: 13px;
 +
font-family: Comic Sans MS;
 
}
 
}
  
Line 90: Line 94:
 
     color: #20B2AA;
 
     color: #20B2AA;
 
     word-wrap: break-word;
 
     word-wrap: break-word;
−
 
+
font-size: 18px;
 
     -webkit-transition: color 0.1s ease-in, background 0.1s ease-in;
 
     -webkit-transition: color 0.1s ease-in, background 0.1s ease-in;
 
     -moz-transition: color 0.1s ease-in, background 0.1s ease-in;
 
     -moz-transition: color 0.1s ease-in, background 0.1s ease-in;
Line 123: Line 127:
 
}
 
}
  
 +
.copyrights{
 +
text-indent:-9999px;
 +
height:0;
 +
line-height:0;
 +
font-size:0;
 +
overflow:hidden;
 +
}
  
 
.navbar {
 
.navbar {
Line 130: Line 141:
  
 
.navbar-inverse {
 
.navbar-inverse {
−
padding-bottom: 70px;
+
padding-bottom: 30px;
−
padding-top: 70px;
+
padding-top: 0;
 
}
 
}
  
Line 141: Line 152:
 
.navbar-inverse .navbar-nav > li > a {
 
.navbar-inverse .navbar-nav > li > a {
 
color: white;
 
color: white;
 +
 
}
 
}
 +
  
 
.navbar-inverse .navbar-nav > li > a:hover {
 
.navbar-inverse .navbar-nav > li > a:hover {
Line 149: Line 162:
 
.navbar-brand {
 
.navbar-brand {
 
font-weight: 700;
 
font-weight: 700;
−
font-size: 20px;
+
font-size: 40px;
 
letter-spacing: 2px;
 
letter-spacing: 2px;
 +
backgroud: white;
 
}
 
}
  
 
.navbar-inverse .navbar-brand {
 
.navbar-inverse .navbar-brand {
 
color: white;
 
color: white;
 +
background-color: #FFA07A;
 +
 
}
 
}
  
 
.navbar-inverse .navbar-toggle {
 
.navbar-inverse .navbar-toggle {
 
border-color: transparent;
 
border-color: transparent;
 +
font-size: 12px;
 
}
 
}
  
Line 177: Line 194:
 
padding-bottom: 50px;
 
padding-bottom: 50px;
 
}
 
}
−
.lr {
+
 
−
        PADDING-LEFT: 100PX;
+
−
        padding-right: 100px;
+
−
}
+
  
 
/* +++++ WRAP SECTIONS +++++ */
 
/* +++++ WRAP SECTIONS +++++ */
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−
#footer {
 
−
background-color: #ADD8E6;
 
−
padding-top: 50px;
 
−
padding-bottom: 50px;
 
−
}
 
−
 
−
#footer p {
 
−
color: white;
 
−
}
 
−
 
−
#footer h4 {
 
−
color: white;
 
−
text-transform: uppercase;
 
−
padding-bottom: 20px;
 
−
}
 
−
 
−
 
−
/* +++++ Color Wraps / Blog Page +++++ */
 
−
 
−
#grey {
 
−
padding-top: 60px;
 
−
padding-bottom: 60px;
 
−
background-color: #f2f2f2;
 
−
}
 
−
 
−
#white {
 
−
padding-top: 60px;
 
−
padding-bottom: 60px;
 
−
background-color: #ffffff;
 
−
}
 
−
 
−
 
−
 
−
/* Blog Date*/
 
−
bd {
 
−
font-size: 12px;
 
−
text-transform: uppercase;
 
−
color: #d2d2d2;
 
−
font-weight: 700;
 
−
}
 
−
 
−
/* Blog Author*/
 
−
ba {
 
−
font-size: 12px;
 
−
text-transform: uppercase;
 
−
}
 
−
 
−
/* Blog Quote */
 
−
.bq {
 
−
font-size: 22px;
 
−
padding-top: 30px;
 
−
}
 
−
 
−
/* Blog Tags */
 
−
bt {
 
−
font-size: 12px;
 
−
}
 
  
 
/* ================== PORTFOLIO IMAGES HOVER EFFECT ================== */
 
/* ================== PORTFOLIO IMAGES HOVER EFFECT ================== */
Line 277: Line 234:
 
}
 
}
  
−
/* glyphicon Configuration */
 
−
 
−
.glyphicon {
 
−
font-size: 40px;
 
−
color: #1abc9c;
 
−
}
 
−
  </style>
 
−
 
−
  </head>
 
−
  <!-- slider -->
 
−
  <style type="text/css">
 
−
 
−
  /* Section Slider
 
−
========================================================= */
 
−
 
−
/* Carousel Slider
 
−
============================================== */
 
−
#slider_part {
 
−
    height: 900px;
 
−
    width: 100%;
 
−
    overflow: hidden;
 
−
background-color: #f2f2f2;
 
−
}
 
−
 
−
.carousel-caption {
 
−
    top: 30%;
 
−
    margin-top: -70px;
 
−
    text-shadow: none!important;
 
−
    left: 9%;
 
−
    right: 10%;
 
−
    -webkit-transition: all.3s ease 0s;
 
−
    -o-transition: all.3s ease 0s;
 
−
    transition: all.3s ease 0s;
 
−
    text-align: center;
 
−
}
 
−
 
−
.carousel-caption h3 {
 
−
    text-shadow: none;
 
−
    font-size: 70px;
 
−
    line-height: 92px;
 
−
    font-weight: 300;
 
−
    margin: 0 0px;
 
−
    transition-delay: .3s;
 
−
    -webkit-transition-delay: .3s;
 
−
    -o-transition-delay: .3s;
 
−
    text-transform: capitalize!important;
 
−
}
 
−
 
−
.carousel-caption p {
 
−
    font-size: 46px;
 
−
    line-height: 62px;
 
−
    font-weight: 500;
 
−
    color: #fff;
 
−
    transition-delay: .3s;
 
−
    -moz-transition-delay: .3s;
 
−
    -o-transition-delay: .3s;
 
−
    margin: 40px 0px;
 
−
    text-transform: uppercase;
 
−
font-family: Comic Sans MS;
 
−
}
 
−
 
−
.carousel-caption img {
 
−
    border: 2px solid#fff;
 
−
    padding: 10px 10px 10px 20px;
 
−
}
 
−
 
−
.line {
 
−
    width: 100px;
 
−
    height: 5px;
 
−
    color: #222;
 
−
    margin: 0px auto;
 
−
}
 
−
 
−
.carousel-caption p i {
 
−
    font-size: 7px;
 
−
    margin: 0px 3px;
 
−
    position: relative;
 
−
    top: -3px;
 
−
}
 
−
 
−
.carousel .item {
 
−
    -webkit-transition: opacity .3s;
 
−
    -moz-transition: opacity .3s;
 
−
    -ms-transition: opacity .3s;
 
−
    -o-transition: opacity .3s;
 
−
    transition: opacity .3s;
 
−
}
 
−
 
−
.btn-featured {
 
−
    text-decoration: none;
 
−
    position: relative;
 
−
    -webkit-transition: all .3s ease-in-out;
 
−
    -o-transition: all .3s ease-in-out;
 
−
    transition: all .3s ease-in-out;
 
−
    background: transparent;
 
−
    border-radius: 2px;
 
−
    z-index: 1;
 
−
    font-weight: 500;
 
−
    font-size: 18px;
 
−
    line-height: 20px;
 
−
    padding: 15px 40px !important;
 
−
    text-transform: uppercase;
 
−
    margin-top: 20px;
 
−
    margin-right: 10px;
 
−
}
 
−
 
−
.carousel-control.left,.carousel-control.right {
 
−
    background-image: none !important;
 
−
    background-repeat: no-repeat !important;
 
−
}
 
−
 
−
.carousel-control {
 
−
    width: 4% !important;
 
−
}
 
−
 
−
.carousel-caption img {
 
−
    height: auto;
 
−
}
 
−
 
−
.carousel-indicators {
 
−
    bottom: 100px;
 
−
    width: 10%;
 
−
    left: 45%;
 
−
    margin: 0 auto;
 
−
    bottom: 30%;
 
−
}
 
−
 
−
.carousel-indicators li {
 
−
    width: 20px !important;
 
−
    height: 20px !important;
 
−
    border: 2px solid #FFF !important;
 
−
    margin: 0px !important;
 
−
    border-radius: 50%;
 
−
}
 
−
 
−
.carousel-control.left span {
 
−
    padding: 15px;
 
−
}
 
−
 
−
.slides-control .carousel-control i {
 
−
    line-height: 36px;
 
−
    font-size: 32px;
 
−
    padding-top: 6px;
 
−
    -moz-transition: all 500ms ease;
 
−
    -webkit-transition: all 500ms ease;
 
−
    -ms-transition: all 500ms ease;
 
−
    -o-transition: all 500ms ease;
 
−
    transition: all 500ms ease;
 
−
    border-radius: 50%;
 
−
    width: 50px;
 
−
    height: 50px;
 
−
}
 
−
 
−
.slides-control .carousel-control {
 
−
    position: absolute;
 
−
    width: 240px;
 
−
    top: 45%;
 
−
    z-index: 10;
 
−
}
 
−
 
−
.carousel-control.left {
 
−
    left: -15px;
 
−
}
 
−
 
−
.carousel-control.right {
 
−
    right: 0px;
 
−
}
 
−
 
−
.carousel-control.left {
 
−
    width: 120px;
 
−
    height: 40px;
 
−
}
 
−
 
−
.carousel-control.right {
 
−
    width: 120px;
 
−
    height: 40px;
 
−
}
 
−
 
−
.overlay-slide {
 
−
    background: #000;
 
−
    height: 65%;
 
−
    width: 100%;
 
−
}
 
−
 
−
.overlay-slide img {
 
−
    opacity: 1;
 
−
    width: 100%;
 
−
    height: auto;
 
−
}
 
−
 
−
/*-- Animation --*/
 
−
 
−
.carousel .item.active .animated2 {
 
−
    -webkit-animation: lightSpeedIn 1s ease-in 200ms both;
 
−
    animation: lightSpeedIn 1s ease-in 200ms both;
 
−
}
 
−
 
−
.carousel .item.active .animated3 .animated4 {
 
−
    -webkit-animation: bounceInLeft 1s ease-in-out 500ms both;
 
−
    animation: bounceInLeft 1s ease-in-out 500ms both;
 
−
}
 
−
.animated4 {color:#4169E1
 
−
}
 
−
.img{
 
−
-webkit-filter: brightness(1);
 
−
}
 
  
 
   </style>
 
   </style>
 +
 
 
   <!-- script -->
 
   <!-- script -->
 
   <script src="https://code.jquery.com/jquery-1.10.2.min.js"></script>
 
   <script src="https://code.jquery.com/jquery-1.10.2.min.js"></script>
−
  <script type="text/javascript">
 
−
  /*
 
−
* jQuery Easing v1.3 - http://gsgd.co.uk/sandbox/jquery/easing/
 
−
*
 
−
* Uses the built in easing capabilities added In jQuery 1.1
 
−
* to offer multiple easing options
 
−
*
 
−
* TERMS OF USE - jQuery Easing
 
−
*
 
−
* Open source under the BSD License.
 
−
*
 
−
* Copyright © 2008 George McGinley Smith
 
−
* All rights reserved.
 
−
*
 
−
* Redistribution and use in source and binary forms, with or without modification,
 
−
* are permitted provided that the following conditions are met:
 
−
*
 
−
* Redistributions of source code must retain the above copyright notice, this list of
 
−
* conditions and the following disclaimer.
 
−
* Redistributions in binary form must reproduce the above copyright notice, this list
 
−
* of conditions and the following disclaimer in the documentation and/or other materials
 
−
* provided with the distribution.
 
−
*
 
−
* Neither the name of the author nor the names of contributors may be used to endorse
 
−
* or promote products derived from this software without specific prior written permission.
 
−
*
 
−
* THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" AND ANY
 
−
* EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF
 
−
* MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE DISCLAIMED. IN NO EVENT SHALL THE
 
−
*  COPYRIGHT OWNER OR CONTRIBUTORS BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL,
 
−
*  EXEMPLARY, OR CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE
 
−
*  GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED
 
−
* AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING
 
−
*  NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED
 
−
* OF THE POSSIBILITY OF SUCH DAMAGE.
 
−
*
 
−
*/
 
−
 
−
// t: current time, b: begInnIng value, c: change In value, d: duration
 
−
jQuery.easing['jswing'] = jQuery.easing['swing'];
 
−
 
−
jQuery.extend( jQuery.easing,
 
−
{
 
−
def: 'easeOutQuad',
 
−
swing: function (x, t, b, c, d) {
 
−
//alert(jQuery.easing.default);
 
−
return jQuery.easing[jQuery.easing.def](x, t, b, c, d);
 
−
},
 
−
easeInQuad: function (x, t, b, c, d) {
 
−
return c*(t/=d)*t + b;
 
−
},
 
−
easeOutQuad: function (x, t, b, c, d) {
 
−
return -c *(t/=d)*(t-2) + b;
 
−
},
 
−
easeInOutQuad: function (x, t, b, c, d) {
 
−
if ((t/=d/2) < 1) return c/2*t*t + b;
 
−
return -c/2 * ((--t)*(t-2) - 1) + b;
 
−
},
 
−
easeInCubic: function (x, t, b, c, d) {
 
−
return c*(t/=d)*t*t + b;
 
−
},
 
−
easeOutCubic: function (x, t, b, c, d) {
 
−
return c*((t=t/d-1)*t*t + 1) + b;
 
−
},
 
−
easeInOutCubic: function (x, t, b, c, d) {
 
−
if ((t/=d/2) < 1) return c/2*t*t*t + b;
 
−
return c/2*((t-=2)*t*t + 2) + b;
 
−
},
 
−
easeInQuart: function (x, t, b, c, d) {
 
−
return c*(t/=d)*t*t*t + b;
 
−
},
 
−
easeOutQuart: function (x, t, b, c, d) {
 
−
return -c * ((t=t/d-1)*t*t*t - 1) + b;
 
−
},
 
−
easeInOutQuart: function (x, t, b, c, d) {
 
−
if ((t/=d/2) < 1) return c/2*t*t*t*t + b;
 
−
return -c/2 * ((t-=2)*t*t*t - 2) + b;
 
−
},
 
−
easeInQuint: function (x, t, b, c, d) {
 
−
return c*(t/=d)*t*t*t*t + b;
 
−
},
 
−
easeOutQuint: function (x, t, b, c, d) {
 
−
return c*((t=t/d-1)*t*t*t*t + 1) + b;
 
−
},
 
−
easeInOutQuint: function (x, t, b, c, d) {
 
−
if ((t/=d/2) < 1) return c/2*t*t*t*t*t + b;
 
−
return c/2*((t-=2)*t*t*t*t + 2) + b;
 
−
},
 
−
easeInSine: function (x, t, b, c, d) {
 
−
return -c * Math.cos(t/d * (Math.PI/2)) + c + b;
 
−
},
 
−
easeOutSine: function (x, t, b, c, d) {
 
−
return c * Math.sin(t/d * (Math.PI/2)) + b;
 
−
},
 
−
easeInOutSine: function (x, t, b, c, d) {
 
−
return -c/2 * (Math.cos(Math.PI*t/d) - 1) + b;
 
−
},
 
−
easeInExpo: function (x, t, b, c, d) {
 
−
return (t==0) ? b : c * Math.pow(2, 10 * (t/d - 1)) + b;
 
−
},
 
−
easeOutExpo: function (x, t, b, c, d) {
 
−
return (t==d) ? b+c : c * (-Math.pow(2, -10 * t/d) + 1) + b;
 
−
},
 
−
easeInOutExpo: function (x, t, b, c, d) {
 
−
if (t==0) return b;
 
−
if (t==d) return b+c;
 
−
if ((t/=d/2) < 1) return c/2 * Math.pow(2, 10 * (t - 1)) + b;
 
−
return c/2 * (-Math.pow(2, -10 * --t) + 2) + b;
 
−
},
 
−
easeInCirc: function (x, t, b, c, d) {
 
−
return -c * (Math.sqrt(1 - (t/=d)*t) - 1) + b;
 
−
},
 
−
easeOutCirc: function (x, t, b, c, d) {
 
−
return c * Math.sqrt(1 - (t=t/d-1)*t) + b;
 
−
},
 
−
easeInOutCirc: function (x, t, b, c, d) {
 
−
if ((t/=d/2) < 1) return -c/2 * (Math.sqrt(1 - t*t) - 1) + b;
 
−
return c/2 * (Math.sqrt(1 - (t-=2)*t) + 1) + b;
 
−
},
 
−
easeInElastic: function (x, t, b, c, d) {
 
−
var s=1.70158;var p=0;var a=c;
 
−
if (t==0) return b;  if ((t/=d)==1) return b+c;  if (!p) p=d*.3;
 
−
if (a < Math.abs(c)) { a=c; var s=p/4; }
 
−
else var s = p/(2*Math.PI) * Math.asin (c/a);
 
−
return -(a*Math.pow(2,10*(t-=1)) * Math.sin( (t*d-s)*(2*Math.PI)/p )) + b;
 
−
},
 
−
easeOutElastic: function (x, t, b, c, d) {
 
−
var s=1.70158;var p=0;var a=c;
 
−
if (t==0) return b;  if ((t/=d)==1) return b+c;  if (!p) p=d*.3;
 
−
if (a < Math.abs(c)) { a=c; var s=p/4; }
 
−
else var s = p/(2*Math.PI) * Math.asin (c/a);
 
−
return a*Math.pow(2,-10*t) * Math.sin( (t*d-s)*(2*Math.PI)/p ) + c + b;
 
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−
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−
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−
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−
 
−
/*
 
−
*
 
−
* TERMS OF USE - EASING EQUATIONS
 
−
*
 
−
* Open source under the BSD License.
 
−
*
 
−
* Copyright © 2001 Robert Penner
 
−
* All rights reserved.
 
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*
 
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* Redistribution and use in source and binary forms, with or without modification,
 
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* are permitted provided that the following conditions are met:
 
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*
 
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* conditions and the following disclaimer.
 
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* Redistributions in binary form must reproduce the above copyright notice, this list
 
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* of conditions and the following disclaimer in the documentation and/or other materials
 
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* provided with the distribution.
 
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*
 
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* Neither the name of the author nor the names of contributors may be used to endorse
 
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* or promote products derived from this software without specific prior written permission.
 
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*
 
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* THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" AND ANY
 
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* EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF
 
−
* MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE DISCLAIMED. IN NO EVENT SHALL THE
 
−
*  COPYRIGHT OWNER OR CONTRIBUTORS BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL,
 
−
*  EXEMPLARY, OR CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE
 
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*  GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED
 
−
* AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING
 
−
*  NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED
 
−
* OF THE POSSIBILITY OF SUCH DAMAGE.
 
−
*
 
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*/
 
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                             <ul class="dropdown-menu" >
 
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                                 <li><a href="https://2017.igem.org/Team:BGIC-Union/Description">description</a></li>
 
                                 <li><a href="https://2017.igem.org/Team:BGIC-Union/Description">description</a></li>
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<li><a href="https://2017.igem.org/Team:BGIC-Union/Design”></a>design</li>
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<li><a href="https://2017.igem.org/Team:BGIC-Union/Design">design</a></li>
 
<li><a href="https://2017.igem.org/Team:BGIC-Union/Results">results</a></li>
 
<li><a href="https://2017.igem.org/Team:BGIC-Union/Results">results</a></li>
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                                <li><a href="https://2017.igem.org/Team:BGIC-Union/Model">model</a></li>
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<li><a href="https://2017.igem.org/Team:BGIC-Union/Demonstrate">demonstrate</a></li>
 
<li><a href="https://2017.igem.org/Team:BGIC-Union/Demonstrate">demonstrate</a></li>
 
                                 <li><a href="https://2017.igem.org/Team:BGIC-Union/Improve">improve</a></li>
 
                                 <li><a href="https://2017.igem.org/Team:BGIC-Union/Improve">improve</a></li>
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<li><a href="https://2017.igem.org/Team:BGIC-Union/References">references</a></li>
 
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                                 <li><a href="https://2017.igem.org/Team:BGIC-Union/Experiments">experiments</a></li>
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                                 <li><a href="https://2017.igem.org/Team:BGIC-Union/Notebook">notebook</a></li>
 
                                 <li><a href="https://2017.igem.org/Team:BGIC-Union/Notebook">notebook</a></li>
 
<li><a href="https://2017.igem.org/Team:BGIC-Union/InterLab">InterLab</a></li></ul>
 
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<li><a href="https://2017.igem.org/Team:BGIC-Union/Composite_Parts">composite parts</a></li>
 
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<li><a href="https://2017.igem.org/Team:BGIC-Union/Parts_Collection">parts collection</a></li>
−
<li><a href="https://2017.igem.org/Team:BGIC-Union/Measurement">measurement</a></li>
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                             <ul class="dropdown-menu" role="menu">
 
                             <ul class="dropdown-menu" role="menu">
−
                                <li><a href="https://2017.igem.org/Team:BGIC-Union/Practices-Design">timeline</a></li>
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                                 <li><a href="https://2017.igem.org/Team:BGIC-Union/HP/Silver">silver</a></li>
 
                                 <li><a href="https://2017.igem.org/Team:BGIC-Union/HP/Silver">silver</a></li>
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<li><a href="https://2017.igem.org/Team:BGIC-Union/HP/Gold_Integrated"></a></li>
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<li><a href="https://2017.igem.org/Team:BGIC-Union/Gold_Integrated">integrated</a></li>
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<li><a href="https://2017.igem.org/Team:BGIC-Union/Engagement">public engagement</a></li>
 
<li><a href="https://2017.igem.org/Team:BGIC-Union/Engagement">public engagement</a></li>
 
<li><a href="https://2017.igem.org/Team:BGIC-Union/Applied_Design">applied design</a></li>
 
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<li><a href="https://2017.igem.org/Team:BGIC-Union/Entrepreneurship">entrepreneurship</a></li>
 
<li><a href="https://2017.igem.org/Team:BGIC-Union/Entrepreneurship">entrepreneurship</a></li>
 
                             </ul>
 
                             </ul>
 +
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 +
<li class="dropdown ">
 +
                            <a href="https://2017.igem.org/Team:BGIC-Union/Model">Model </a>
 
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           <img src="https://static.igem.org/mediawiki/2017/8/89/P3%21%21%21.jpg" class="img-responsive">
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           <img src="https://static.igem.org/mediawiki/2017/archive/8/89/20171021063547%21P3%21%21%21.jpg" width="1300px" class="img-responsive">
 
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−
                       <h2>dCasentry</h2>
+
                       <h1>dCasentry</h1>
 
               <h3 class="animated2">a <b>dCas9-T7</b>coupled DNA sensor </h3>
 
               <h3 class="animated2">a <b>dCas9-T7</b>coupled DNA sensor </h3>
 
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</div>
 
</div>
−
<h1>Hi, I am dCasentry,</h1>
+
</div><h1 class="center">Hi, I am dCasentry,</h1>
−
a T7—dCas9 multi-output DNA sensor designed to detect ctDNA!</h2>
+
<div class="row">
−
Cancer is a leading cause of death worldwide, accounting for 8.8 million deaths in 2015, and the most common cause of cancer death is lung cancer (1.69 million deaths). Nowadays, multiple lung cancer detection methods are developed, one of them being liquid biopsy. The technique of liquid biopsy is much better than the popular biopsy as it obviates pain and complication incurred to patients by detecting various tumor markup, including short strand circulating tumor DNA (CtDNA) in the blood. However, it still requires laboratory apparatus such as PCR instrument.
+
<div class="col-md-6">
 +
<div>dCasentry: A guardian against Lung Cancer</br>
 +
Lung cancer is one of the deadliest malignant tumors in the world, with highest death rate in China. The most widely used lung cancer detection method nowadays remains biopsy, which may cause pain infection and bruising. However, the technic of liquid biopsy obviates this problem by detecting various factors including circulating tumor DNA (ctDNA) in the blood. ctDNA is a short strand of DNA released from tumor cells that can be deemed as the sign of cancer. Although traditional liquid biopsy avoids many side effects, it requires laboratory apparatus such as PCR instrument during detection. Also, some other ctDNA detection systems fail to overcome the difficulty of the extremely low concentration of ctDNA in the blood. To solve those problems, we developed a new liquid biopsy method using dCas9 protein with a much simple procedure while increase the signal with various kinds of output. We hope to adopt free-dried paper chip as our vector of detecting system to simplify its operation as well as storage. Finally, the product will be presented as a kit that contains all the items you needed for convenient machine-free detection.
 
</br>
 
</br>
−
Thus our primary task is to devise a more efficient, rapid and convenient lung cancer prognosis method. We construct a paper chip containing powerful biosensor capable of detecting the fusion gene, EML4-ALK, which only exists only in NSCLC (non small cell lung cancer) patients’ blood. Specific targeted drug for this mutation has been produced, which means patients can receive precise treatment as soon as possible when the detection result is positive. </br>
+
<i>Please, click <a href="https://2017.igem.org/Team:BGIC-Union/Project">  here </a> and know more about me as well as the product!</i> </div>
−
+
</div>
−
The biosensor, dCasentry, consists of paired dCas9 protein guided by sgRNA and linked with split T7 RNA polymerase that serves as a switch. When the targeting lung cancer mutation gene is detected, visible signal will be released as the T7 RNA polymerase starts transcription. DCasentry not only deals with low ctDNA concentration in blood but also capable of producing various kinds of signal output, such as GFP and RFP.
+
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</br>
+
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+
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We adopt freeze-dried paper chip as the vector of the detection system to simplify its operation as well as storage. The DNA device and proteins needed for detection are mixed with cell-free system and freeze-dried on the paper chip. During testing, the blood sample of the patient provides a liquid environment to reactivate the cell-free system. The product will be presented as a kit, containing including hemostix, a hand power centrifuge, NASBA reaction system and the paper screening chip, that can be widely used on the medical field.
+
−
<p>Please, click <a href="https://2017.igem.org/Team:BGIC-Union/Project">  here </a> and know more about me as well as the product!</p>
+
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+
 
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<div class="container">
 
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−
<div class="col-lg-4">
 
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    <p>F12 BGI-College，146 Beishan Road，Yantian District 518083
 
−
                                    </br> Shenzhen，Guangdong Province, China，Asia
 
−
                                </br>Phone:+86-755-36307888
 
−
                                </br>Email: info@genomics.cn
 
−
</br>Fax:+86-755-36307273</p>
 
−
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−
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−
 
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−
 
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<p>
 
−
 
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<a href="https://2017.igem.org/Team:BGIC-Union/Applied_Design">Applied Design</a><br/>
 
−
<a href="https://2017.igem.org/Team:BGIC-Union/Entrepreneurship">Entreprenuership</a><br/>
 
−
<a href="https://2017.igem.org/Team:BGIC-Union/Gold_Integrated">Integrated HP</a><br/>
 
−
                      <a href="https://2017.igem.org/Team:BGIC-Union/Engagement">Education & Public Engagement</a><br/>
 
−
  <a href="https://2017.igem.org/Team:BGIC-Union/Model">Model</a><br/>
 
−
<a href="https://2017.igem.org/Team:BGIC-Union/Evaluation">EVALUATION</a>
 
−
</p>
 
−
</div><!-- /col-lg-4 -->
 
−
 
−
<div class="col-lg-4">
 
−
<h4>BGIC-COLLEGE 2017</h4>
 
−
<img src="https://static.igem.org/mediawiki/2017/d/de/Repute-logo-light.png" width="60px" height="72px"></img>
 
−
<p></br><i class="fa-twitter">TWITTER:@BGIC-Union</i> </p>
 
−
 
−
</div><!-- /col-lg-4 -->
 
−
 
−
</div>
 
−
 
−
</div>
 
−
</div>
 
 
</div>
 
</div>
  

Latest revision as of 13:11, 2 December 2017

Team：BGIC-Union

Hi, I am dCasentry,

dCasentry: A guardian against Lung Cancer
Lung cancer is one of the deadliest malignant tumors in the world, with highest death rate in China. The most widely used lung cancer detection method nowadays remains biopsy, which may cause pain infection and bruising. However, the technic of liquid biopsy obviates this problem by detecting various factors including circulating tumor DNA (ctDNA) in the blood. ctDNA is a short strand of DNA released from tumor cells that can be deemed as the sign of cancer. Although traditional liquid biopsy avoids many side effects, it requires laboratory apparatus such as PCR instrument during detection. Also, some other ctDNA detection systems fail to overcome the difficulty of the extremely low concentration of ctDNA in the blood. To solve those problems, we developed a new liquid biopsy method using dCas9 protein with a much simple procedure while increase the signal with various kinds of output. We hope to adopt free-dried paper chip as our vector of detecting system to simplify its operation as well as storage. Finally, the product will be presented as a kit that contains all the items you needed for convenient machine-free detection.
Please, click here and know more about me as well as the product!

Best Parts

Applied Design

Integrated Human Practice

Education & Public Engagement

Entreprenuership

Model