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| − | {{Oxford}}
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| − | <html>
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| − | <head>
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| − | <meta name="viewport" content="width=device-width, initial-scale=1.0"/>
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| − | <style>
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| − | canvas {
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| − | background-color: #e8d5d7;
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| − | width:80%;
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| − | }
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| − | #canvas_happy{
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| − | background-color: #002147;
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| − | }
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| | | | |
| − | hr {
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| − | display: block;
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| − | height: 1px;
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| − | border: 0;
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| − | border-top: 1px solid black;
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| − | margin: 1em 0;
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| − | padding: 0;
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| − | }
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| − |
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| − | .btn-circle {
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| − | width: 50px;
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| − | height: 50px;
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| − | padding: 10px 16px;
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| − | border-radius: 50%;
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| − | font-size: 24px;
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| − | line-height: 1.33;
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| − | background-color: rgba(95,155,175,0.9);
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| − | }
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| − |
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| − | .btn-circle-lg {
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| − | width: 240px;
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| − | height: 240px;
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| − | padding: 10px 16px;
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| − | border-radius: 50%;
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| − | font-size: 60px;
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| − | line-height: 1.33;
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| − | }
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| − |
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| − | .carousel-caption a {
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| − | font-size: 50px;
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| − | font-weight: bolder;
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| − | text-shadow: 1px 3px 5px rgba(0,0,0,0.8);
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| − | color: white;
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| − | }
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| − |
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| − | #button-span {
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| − | font-weight: bold;
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| − | font-size: 20px;
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| − | color: black;
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| − | line-height: 0.2;
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| − | text-align:center;
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| − | position: relative;
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| − | left: 0px;
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| − | right: 0px;
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| − | display: block;
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| − | }
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| − |
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| − | #button-lg-span {
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| − | font-weight: bold;
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| − | font-size: 20px;
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| − | color: black;
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| − | line-height: 1;
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| − | text-align:center;
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| − | position: relative;
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| − | left: 0px;
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| − | right: 0px;
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| − | display: block;
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| − | }
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| − | #bodyContent .colourbox {
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| − | list-style-type: none;
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| − | background-color: #DCE7EF;
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| − | border-radius: 25px;
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| − | }
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| − | #bodyContent ul{
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| − | list-style-type: none;
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| − | }
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| − | #circles_home {
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| − | margin: 50px 50px 50px 80px;
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| − | }
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| − | #texthome{
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| − | width: 80%;
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| − | }
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| − |
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| − | </style>
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| − | </head>
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| − | <body onload="startStartScreen()">
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| − |
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| − |
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| − | <img id="magnify-glass" src="https://static.igem.org/mediawiki/2017/a/a6/T--oxford--manifying-glass.png" style = "display:none">
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| − | <img id="red-blood-cell" src = "https://static.igem.org/mediawiki/2017/d/d6/T--oxford--home-rbc.png" style = "display:none">
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| − | <img id="t-cruzi" src = "https://static.igem.org/mediawiki/2017/4/42/T--oxford--t_cruzi_cartoon.png" style = "display: none">
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| − | <img id="start_screen_img" src = "https://static.igem.org/mediawiki/2017/7/72/T--oxford--home--landing_page.png" style = "display: none">
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| − |
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| − |
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| − | <div>
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| − | <div id='canvas_happy' class="container-fluid">
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| − | <div id='header' style="margin-top: 100px"></div>
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| − | <div id="wrapper" role="wrapper">
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| − | <center><canvas id="main" width="800" height="452" style="display: block; background-color: #f7eff0;"></canvas></center>
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| − | </div>
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| − | <div id='header' style="margin-top: 100px"></div>
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| − | </div>
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| − | <div class="container-fluid">
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| − | <div style="margin-top: 50px"></div>
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| − | <center><div id="texthome">
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| − | <div class="embed-responsive embed-responsive-16by9">
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| − | <iframe class="embed-responsive-item" src="https://www.youtube.com/embed/4heo3c2qvWo" frameborder="0" gesture="media" allow="encrypted-media" allowfullscreen></iframe>
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| − | </div>
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| − | <p>The aim of our project was to develop a cell-free detection system for congenital Chagas disease in the acute phase by detecting the cruzipain in the blood.
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| − | Congenital Chagas disease is a growing global concern and at present, the acute phase of Chagas disease is difficult to diagnose as it is asymptomatic and current diagnostics are both expensive and inaccessible to the majority of those affected. Our final diagnostic kit would allow Chagas disease to be detected by preventing the clotting of a blood sample. </p>
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| − | <p> We imagine that this system would be adaptable for other parasites and pathogens which have similar difficulties in detection, both in the input for the system and the options for output.</p>
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| − | <br>
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| − | </div></center>
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| − | </div>
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| − | </div>
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| − |
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| − | <script>
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| − |
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| − | var myGamePiece;
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| − | var cells_size = 250;
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| − | var cells = [cells_size];
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| − | var tCruzi;
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| − | var delay = 0;
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| − | var magnification = 2;
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| − | var rbc_w = 60/2;
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| − | var rbc_h = 53/2;
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| − | var t_cruzi_w = 50;
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| − | var t_cruzi_h = 81; //t cruzi image height
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| − | var magnify_w = 2874;
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| − | var magnify_h = 3475;
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| − | var peek_size = 100;
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| − | var time;
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| − | var checked = false;
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| − | var found = false;
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| − |
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| − | function startStartScreen(){
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| − | document.getElementById('main').style.cursor = "block";
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| − | //document.getElementById('header').style.cursor = "block";
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| − | //document.getElementById('title').style.cursor = "block";
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| − | myStartScreen.start();
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| − | //console.log('startScreen');
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| − | }
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| − |
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| − | function startGame() {
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| − | document.getElementById('main').style.cursor = "none";
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| − | //document.getElementById('header').style.cursor = "none";
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| − | //document.getElementById('title').style.cursor = "none";
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| − | myGamePiece = new createMouse(10, 120);
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| − | myGameArea.start();
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| − | initialize();
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| − | //console.log('startGame');
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| − | }
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| − |
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| − | function initialize(){
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| − | for (var i = 0; i < cells_size; i++ ) {
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| − | var dirr = (Math.random() * 2 * Math.PI);
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| − | var posx = (Math.random() * (main.width - 60));
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| − | var posy = (Math.random() * (main.height - 53));
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| − | cells[i] = new createComponent(posx,posy,dirr,"cell");
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| − |
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| − | }
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| − | var dirr = (Math.random() * 2 * Math.PI);
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| − | var posx = (Math.random() * (main.width - 50));
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| − | var posy = (Math.random() * (main.height - 81));
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| − | tCruzi = new createComponent(posx,posy,dirr,"parasite");
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| − | time = new createComponent(30, 30, 0, "time");
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| − |
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| − | }
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| − |
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| − |
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| − | var myStartScreen = {
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| − | start : function(){
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| − | this.frameNo = 0;
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| − | this.interval = setInterval(updateStartScreen, 20);
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| − | window.addEventListener('mousemove', function(e){
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| − | myStartScreen.x = e.pageX;
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| − | myStartScreen.y = e.pageY-200;
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| − | })
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| − | myStartScreen.mouseClick = false
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| − | window.addEventListener('mousedown', function(e){
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| − | xleft = $("#main").offset().left; //getting the coordinates of the canvas
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| − | ytop = $("#main").offset().top;
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| − | xright = $("#main").offset().left + $("#main").outerWidth();
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| − | ybottom = $("#main").offset().top + $("#main").outerHeight();
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| − | //console.log(e.pageX);
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| − | //console.log(e.pageY);
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| − | if(e.pageX < xright){
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| − | if(e.pageX > xleft){
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| − | if(e.pageY < ybottom){
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| − | if(e.pageY > ytop){
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| − | myStartScreen.mouseClick = true;
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| − | }
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| − | }
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| − | //console.log("mouth inside detected");
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| − | }
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| − | }
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| − |
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| − | })
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| − | /*window.addEventListener('resize',function(e){
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| − | $("#main").outerHeight(($(window).height()-$("#main").offset().top- Math.abs($("#main").outerHeight(true) - $("#main").outerHeight()))*0.8);
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| − | })*/
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| − | },
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| − | clear : function() {
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| − | main.getContext("2d").clearRect(0, 0, main.width, main.height);
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| − | },
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| − | stop : function(){
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| − | clearInterval(this.interval);
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| − | }
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| − |
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| − | }
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| − |
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| − | var myGameArea = {
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| − | start : function() {
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| − | this.frameNo = 0;
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| − | this.interval = setInterval(updateGameArea, 20);
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| − | window.addEventListener('mousemove', function(e){
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| − | myGameArea.x = e.pageX;
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| − | myGameArea.y = e.pageY-200;
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| − | })
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| − | myGameArea.mouseSensor = false;
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| − | window.addEventListener('mousedown', function(e){
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| − | xleft = $("#main").offset().left; //getting the coordinates of the canvas
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| − | ytop = $("#main").offset().top;
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| − | xright = $("#main").offset().left + $("#main").outerWidth();
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| − | ybottom = $("#main").offset().top + $("#main").outerHeight();
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| − | console.log(xleft);
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| − | console.log(xright);
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| − | console.log(e.pageX);
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| − | console.log(ytop);
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| − | console.log(ybottom);
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| − | console.log(e.pageY);
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| − | if(e.pageX < xright){
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| − | if(e.pageX > xleft){
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| − | if(e.pageY < ybottom){
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| − | if(e.pageY > ytop){
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| − | myGameArea.mouseSensor = true;
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| − | }
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| − | }
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| − | }
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| − | }
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| − |
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| − | })
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| − | },
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| − | clear : function() {
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| − | main.getContext("2d").clearRect(0, 0, main.width, main.height);
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| − | },
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| − | stop : function() {
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| − | clearInterval(this.interval);
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| − |
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| − | }
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| − | }
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| − |
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| − | function createMouse(x, y) {
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| − | this.x = x;
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| − | this.y = y;
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| − |
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| − | this.update = function(){
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| − | main.style.display = "block";
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| − | ctx = main.getContext("2d");
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| − | var img = document.getElementById("magnify-glass");
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| − | ctx.drawImage(img, this.x-magnify_w/22-13, this.y-magnify_w/22+13, magnify_w/11, magnify_h/11);
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| − | ctx.save();
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| − | ctx.beginPath();
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| − | ctx.arc(this.x, this.y, peek_size, 0, 2 * Math.PI);
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| − | ctx.fillStyle = 'rgb(255, 237, 237)';
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| − | ctx.fill();
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| − | //ctx.lineWidth = 3;
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| − | ctx.strokeStyle = '#003300';
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| − | //ctx.stroke();
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| − | ctx.clip();
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| − | ctx.restore()
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| − | }
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| − |
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| − | this.updateFound = function(){
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| − | main.style.display = "block";
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| − | ctx = main.getContext("2d");
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| − | var img = document.getElementById("magnify-glass");
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| − | ctx.drawImage(img, this.x-magnify_w/22-13, this.y-magnify_w/22+13, magnify_w/11, magnify_h/11);
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| − | ctx.save();
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| − | ctx.beginPath();
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| − | ctx.arc(this.x, this.y, peek_size, 0, 2 * Math.PI);
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| − | ctx.fillStyle = "rgba(0,33,71,.5)";
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| − | ctx.fill();
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| − | //ctx.lineWidth = 3;
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| − | ctx.strokeStyle = '#003300';
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| − | ctx.font = "20px Calibri";
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| − | ctx.fillStyle = "#FFFFFF";
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| − | this.text1 = " Yay!"
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| − | this.text2 = " You've found"
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| − | this.text3 = " it in " + Math.round(myGameArea.frameNo*20/1000) + " seconds. In"
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| − | this.text4 = " practice, it takes 5-10"
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| − | this.text5 = " minutes for a sample"
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| − | this.text6 = " of blood under the"
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| − | this.text7 = " microscope."
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| − | ctx.fillText(this.text1, this.x-80, this.y-80);
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| − | ctx.fillText(this.text2, this.x-80, this.y-60);
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| − | ctx.fillText(this.text3, this.x-80, this.y-40);
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| − | ctx.fillText(this.text4, this.x-90, this.y-20);
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| − | ctx.fillText(this.text5, this.x-100, this.y);
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| − | ctx.fillText(this.text6, this.x-90, this.y+20);
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| − | ctx.fillText(this.text7, this.x-80, this.y+40);
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| − | ctx.font = "15px Calibri";
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| − | ctx.fillStyle = "#FFFFFF";
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| − | this.text9 = "click for"
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| − | ctx.fillText(this.text9, this.x-20, this.y+60);
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| − |
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| − |
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| − | ctx.font = "35px Calibri";
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| − | ctx.fillStyle = "#1569d6";
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| − | this.text8 = "RESTART"
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| − | ctx.fillText(this.text8, this.x-58, this.y+90);
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| − |
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| − | //ctx.stroke();
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| − | //ctx.clip();
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| − | ctx.restore();
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| − | if (myGameArea.mouseSensor) {
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| − | checked = false;
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| − | found=false;
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| − | myGameArea.stop();
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| − | startStartScreen();
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| − | //console.log("mouse detected after found");
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| − | }
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| − |
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| − | }
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| − |
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| − | this.found = function(){
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| − | var distance_x = Math.abs(this.x - tCruzi.x - t_cruzi_w/8);
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| − | var distance_y = Math.abs(this.y - tCruzi.y - t_cruzi_h/8);
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| − | if ((distance_x*distance_x + distance_y*distance_y) < 100){
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| − | return true;
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| − | }
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| − | else {return false;}
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| − | }
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| − | }
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| − |
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| − | function createComponent(x, y, dir, type){
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| − | this.type = type;
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| − | this.x = x;
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| − | this.y = y;
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| − | this.dir = dir;
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| − | this.is_peeking = false;
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| − | this.dx = 0;
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| − | this.dy = 0;
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| − | this.distance = 0;
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| − | this.peek_calc = function(on_canvas){
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| − | if (on_canvas)
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| − | {
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| − | this.dx = myGameArea.x - this.x;
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| − | this.dy = myGameArea.y - this.y;
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| − | this.distance = Math.sqrt(this.dx*this.dx + this.dy*this.dy);
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| − | this.is_peeking = (this.distance < peek_size * 1.5)? true:false;
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| − | }
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| − | else
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| − | {
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| − | this.is_peeking = false;
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| − | }
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| − | }
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| − | this.draw_main = function(){
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| − | ctx = main.getContext("2d");
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| − | if(this.type == "cell"){
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| − |
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| − | var img = document.getElementById("red-blood-cell");
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| − | ctx.drawImage(img, this.x, this.y, rbc_w, rbc_h);
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| − | }
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| − | if(this.type == "parasite"){
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| − |
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| − | var img = document.getElementById("t-cruzi");
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| − | ctx.drawImage(img, this.x, this.y, t_cruzi_w/4, t_cruzi_h/4);
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| − | }
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| − | //if(this.type)
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| − | }
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| − |
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| − | this.draw_peek = function(){
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| − | if (this.is_peeking)
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| − | {
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| − | ctx = main.getContext("2d");
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| − | ctx.save();
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| − | ctx.beginPath();
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| − | ctx.arc(myGameArea.x, myGameArea.y, peek_size, 0, 2 * Math.PI);
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| − | ctx.clip();
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| − | if(this.type == "cell"){
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| − |
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| − | var img = document.getElementById("red-blood-cell");
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| − | ctx.drawImage(img, (this.x - this.dx * magnification), (this.y - this.dy * magnification), rbc_w * magnification * 1.5, rbc_h * magnification * 1.5);
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| − | }
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| − | if(this.type == "parasite"){
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| − |
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| − | var img = document.getElementById("t-cruzi");
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| − | ctx.drawImage(img, (this.x - this.dx * magnification), (this.y - this.dy * magnification), t_cruzi_w/4 * magnification * 1.5, t_cruzi_h/4 * magnification * 1.5);
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| − | }
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| − |
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| − | ctx.restore();
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| − | }
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| − | }
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| − |
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| − | this.move = function(){
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| − |
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| − | var newXDirection = 0.1*Math.cos(this.dir);
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| − | var newYDirection = 0.1*Math.sin(this.dir);
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| − | this.x += newXDirection;
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| − | this.y += newYDirection;
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| − |
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| − | var bottomline = main.height - rbc_h;
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| − | var rightline = main.width - rbc_w;
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| − | if(this.y > bottomline || this.x > rightline || this.y < 0 || this.x < 0){
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| − |
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| − | this.x -= newXDirection*2;
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| − | this.y -= newYDirection*2;
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| − |
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| − | }
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| − |
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| − | }
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| − |
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| − | this.updateTime = function(){
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| − | ctx.font = "30px Arial";
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| − | ctx.fillStyle = "#000000";
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| − | ctx.fillText(this.text, this.x, this.y);
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| − | }
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| − |
| |
| − | }
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| − |
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| − | function centerText(ctx, text, y) {
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| − | var measurement = ctx.measureText(text);
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| − | var x = (ctx.canvas.width - measurement.width) / 2;
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| − | ctx.fillText(text, x-50, y);
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| − | }
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| − |
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| − | var title = 'Finding T. Cruzi';
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| − | var hue = 0;
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| − | var direction = 1;
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| − | var ctx = main.getContext('2d');
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| − | var wasButtonDown = false;
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| − |
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| − | function updateStartScreen(){
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| − | hue += 1 * direction;
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| − | if (hue > 255) direction = -1;
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| − | if (hue < 78) direction = 1;
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| − |
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| − | var y = ctx.canvas.height / 2;
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| − | var color = 'rgb(7,38,' + hue + ')';
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| − |
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| − | myStartScreen.clear();
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| − |
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| − | var img = document.getElementById("start_screen_img");
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| − | ctx.drawImage(img, 0, 0, 800, 452);
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| − | //ctx.drawImage(img, 0, 0, main.height*start_screen_img.width/start_screen_img.height, main.height);
| |
| − | //console.log(main.width);
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| − | //console.log(main.height);
| |
| − | /*var screen_height = $("#main").outerHeight();
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| − | var screen_width = $("#main").outerWidth();
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| − | var screen_width_height_ratio = screen_width/screen_height;
| |
| − | var ssi_width_height_ratio = start_screen_img.width/start_screen_img.height;//ssi = start screen img
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| − | //console.log(ssi_width_height_ratio);//working correctly
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| − | //console.log(screen_width_height_ratio);//working correctly
| |
| − | //console.log(ssi_width_height_ratio);
| |
| − | if(screen_width_height_ratio>ssi_width_height_ratio){
| |
| − | var start_screen_x = (main.width - main.height*ssi_width_height_ratio)/2;
| |
| − | //console.log('start screen x is' + start_screen_x);
| |
| − | ctx.drawImage(img, start_screen_x, 0, main.height*1.78, main.height);
| |
| − | console.log(screen_height*ssi_width_height_ratio);
| |
| − | console.log(screen_height);
| |
| − | } else{
| |
| − | //if(screen_width_height_ratio<ssi_width_height_ratio){
| |
| − | //console.log("smaller");
| |
| − | /*var start_screen_y = (screen_height - screen_width/ssi_width_height_ratio)/2;
| |
| − | ctx.drawImage(img, 0, start_screen_y, screen_width, screen_width/ssi_width_height_ratio);
| |
| − | console.log(screen_width);
| |
| − | console.log(screen_width/ssi_width_height_ratio);
| |
| − |
| |
| − | ctx.drawImage(img, 0, 0, screen_width, screen_width/ssi_width_height_ratio);
| |
| − | }*/
| |
| − |
| |
| − | ctx.fillStyle = 'white';
| |
| − | ctx.font = '48px monospace';
| |
| − | //centerText(ctx, title, main.height*0.4);
| |
| − |
| |
| − | ctx.fillStyle = color;
| |
| − | ctx.font = '40px Helvetica';
| |
| − | //centerText(ctx, 'click to begin', main.height*0.9);
| |
| − |
| |
| − |
| |
| − | if (myStartScreen.mouseClick) {
| |
| − | // do something here to transition to the actual game
| |
| − | myStartScreen.stop();
| |
| − | startGame();
| |
| − | //console.log('startgamefromclick');
| |
| − |
| |
| − | }
| |
| − | }
| |
| − |
| |
| − |
| |
| − | function updateGameArea() {
| |
| − | var on_screen = false;
| |
| − | if (myGameArea.x){
| |
| − | if(myGameArea.y){
| |
| − | myGamePiece.x = myGameArea.x;
| |
| − | myGamePiece.y = myGameArea.y;
| |
| − | on_screen = true;
| |
| − | }
| |
| − | }
| |
| − |
| |
| − |
| |
| − | myGameArea.clear();
| |
| − | if(checked == false){
| |
| − | found = myGamePiece.found();
| |
| − | if(found) {
| |
| − | checked = true;
| |
| − | //console.log("checked = true")
| |
| − | //myGameArea.stop();
| |
| − | }
| |
| − | }
| |
| − |
| |
| − | if(!found){myGameArea.frameNo += 1;} //stop the timing when t cruzi is found
| |
| − |
| |
| − |
| |
| − |
| |
| − | myGamePiece.update();
| |
| − |
| |
| − | delay += 1;
| |
| − | if (delay >= 2) {
| |
| − | for (var i = 0; i < cells.length; i++) {
| |
| − | cells[i].dir += (Math.random() * Math.PI/5) - (Math.PI/10);
| |
| − | cells[i].move();
| |
| − | cells[i].peek_calc(on_screen);
| |
| − | }
| |
| − | tCruzi.dir += (Math.random() * Math.PI/5) - (Math.PI/10);
| |
| − | tCruzi.move();
| |
| − | tCruzi.peek_calc(on_screen);
| |
| − | }
| |
| − |
| |
| − | for (var i = 0; i < cells.length; i++ ) {
| |
| − | //console.log("cell" + i + "is updated");
| |
| − | cells[i].draw_main();
| |
| − |
| |
| − | }
| |
| − | //tCruzi.draw_main();
| |
| − |
| |
| − |
| |
| − |
| |
| − | myGamePiece.update();
| |
| − | //console.log(tCruzi.type);
| |
| − | for (var i = 0; i < cells.length; i++ ) {
| |
| − | //console.log("cell" + i + "is updated");
| |
| − | cells[i].draw_peek();
| |
| − |
| |
| − | }
| |
| − | tCruzi.draw_peek();
| |
| − |
| |
| − | time.text="time elapsed: " + Math.round(myGameArea.frameNo*20/1000) + " seconds";
| |
| − | time.updateTime();
| |
| − |
| |
| − |
| |
| − | if (found)
| |
| − | {myGamePiece.updateFound();
| |
| − | //console.log("third update");
| |
| − | }
| |
| − | }
| |
| − |
| |
| − | </script>
| |
| − |
| |
| − | <br/>
| |
| − |
| |
| − | <div id="circles_home">
| |
| − | <div class="row">
| |
| − |
| |
| − | <div class="col-sm-3">
| |
| − | <form action="https://2017.igem.org/Team:Oxford/Description">
| |
| − | <button type="submit" class="btn btn-default btn-circle-lg" style="background-color: rgb(72,145,220)"><span id="button-lg-span">Project<br>Description</span></button>
| |
| − | </form>
| |
| − | </div>
| |
| − |
| |
| − | <div class="col-sm-3">
| |
| − | <form action="https://2017.igem.org/Team:Oxford/Overview_Wet_Lab">
| |
| − | <button type="submit" class="btn btn-default btn-circle-lg" style="background-color: rgb(234,139,68)"><span id="button-lg-span">Wet Lab<br>Overview</span></button>
| |
| − | </form>
| |
| − | </div>
| |
| − |
| |
| − | <div class="col-sm-3">
| |
| − | <form action="https://2017.igem.org/Team:Oxford/Model">
| |
| − | <button type="submit" class="btn btn-default btn-circle-lg" style="background-color: rgb(185, 207, 150)"><span id="button-lg-span">Dry Lab<br>Overview</span></button>
| |
| − | </form>
| |
| − | </div>
| |
| − |
| |
| − | <div class="col-sm-3">
| |
| − | <form action="https://2017.igem.org/Team:Oxford/Applied_Design">
| |
| − | <button type="submit" class="btn btn-default btn-circle-lg" style="background-color: rgb(95, 155, 175)"><span id="button-lg-span">Applied<br>Design</span></button>
| |
| − | </form>
| |
| − | </div>
| |
| − |
| |
| − | </div>
| |
| − | </div>
| |
| − |
| |
| − | </body>
| |
| − |
| |
| − | </html>
| |
| − | {{Oxford/footer}}
| |
