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</nav> | </nav> | ||
<!-- END MENU --> | <!-- END MENU --> | ||
− | + | <!-- SLIDERS --> | |
− | <section> | + | <section class="hero-unit-slider slider-responsive no-margin"> |
− | + | <div id="carousel-hero" class="slick-carousel"> | |
− | + | <div class="carousel-inner" role="listbox"> | |
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− | + | <div class="carousel-caption"> | |
− | </ | + | <h2 class="hero-heading">dCasKnight</h2> |
− | <div | + | <p class="lead">A paired dCas9-T7 coupled biosensor </p> |
− | + | <a href="https://2017.igem.org/Team:BGIC-Union/Project" class="btn btn-lg hero-button">LEARN MORE</a> | |
− | </div> | + | </div> |
− | < | + | </div> |
− | <div class=" | + | <div class="item"> |
− | <div class="container"> | + | <img src="https://static.igem.org/mediawiki/2017/5/51/BGIC-Union_slider2-h500.png" class="img-responsive" alt="Slider Image" height="500" width="1600"> |
− | + | <div class="carousel-caption"> | |
− | + | <h2 class="hero-heading">From Shenzhen BGIC with Love</h2> | |
− | + | <p class="lead">A united team with members from eight cities</p> | |
− | </ | + | <a href="https://2017.igem.org/Team:BGIC-Union/Team" class="btn btn-lg hero-button">KNOW US</a> |
− | <div | + | </div> |
− | + | </div> | |
− | </div> | + | <div class="item"> |
− | < | + | <img src="https://static.igem.org/mediawiki/2017/e/e0/BGIC-Union_slider1-h500.png" class="img-responsive" alt="Slider Image" height="500" width="1600"> |
− | <div class=" | + | <div class="carousel-caption"> |
− | <div class="container"> | + | <h2 class="hero-heading1">Future provision</h2> |
− | + | <p class="lead2">We learn about cancer diagonosis, bio-containment and more</p> | |
− | + | <a href="https://2017.igem.org/Team:BGIC-Union/Practices&Design" class="btn btn-lg hero-button1">HAVE A LOOK</a> | |
− | + | </div> | |
− | </ | + | </div> |
− | <div id=" | + | </div> |
− | + | </div> | |
− | </div> | + | </section> |
− | < | + | <!-- END SLIDERS --> |
− | + | ||
− | + | <section height="500px"> | |
− | + | </section> | |
− | + | <!-- INTRO --> | |
− | + | <section> | |
− | + | <div class="container"> | |
− | + | <div class="row"> | |
− | + | <div class="col-md-6"> | |
− | + | <h2 class="section-heading">DESCRIPTION</h2> | |
− | + | <p class="lead"> | |
− | + | <p> | |
+ | Cancer is one of the most deadly diseases in the world. Cancer accounts for more than 8.8 million deaths in 2015. Lung cancer, one of the top five cancers, took away 1.69 million lives in 2015. Although medicine and cancer treatments have been highly developed overtime, it is still difficult to diagnose and cure lung cancer in its early stage, particularly for non-small cell lung cancer (NSCLC). | ||
+ | </P> | ||
+ | <P> | ||
+ | Our main task is to construct a test paper that contains a powerful biosensor capable of detecting any DNA sequence. The biosensor, which is composed by dcas9 and T7 polymerase coupled system, can act like a smart automatic switch. When the test paper detects a particular DNA sequence, it then releases a visible signal. | ||
+ | |||
+ | For diagnosing NSCLC cancer, we will use our biosensor to detect the fusion gene EML4-ALK, which is thought to have huge connections with lung cancer. The formation of this protein has to do with the alteration that occurred in the chromosomes. The alteration means one small piece of chromosome mysteriously going to the tail of another chromosome. If we are able to use our dcas9 and T7 polymerase coupled system to find EML4-ALK effectively and identify it at an early stage, then we will be creating a faster and safer cancer diagnostic process and immensely help people in pain with NSCLC cancer or even other types of cancers. | ||
+ | |||
+ | </p> | ||
+ | </div> | ||
+ | <div class="col-md-6"> | ||
+ | <img src="https://static.igem.org/mediawiki/2017/1/1b/BGIC-Union_intro-img.png" class="img-responsive" alt="Image Intro"> | ||
+ | </div> | ||
+ | </div> | ||
+ | </div> | ||
+ | </section> | ||
+ | <!-- END INTRO --> | ||
+ | <!-- GOOD POINTS--> | ||
+ | <section> | ||
+ | <div class="container"> | ||
+ | <div class="row"> | ||
+ | <div class="col-md-6"> | ||
+ | <div class="boxed-content left-aligned left-boxed-icon"> | ||
+ | <i class="fa fa-flag"></i> | ||
+ | <h2 class="boxed-content-title">IMPROVED DESIGN</h2> | ||
+ | <p> Based on...we improved</p> | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="col-md-6"> | ||
+ | <div class="boxed-content left-aligned left-boxed-icon"> | ||
+ | <i class="fa fa-globe"></i> | ||
+ | <h2 class="boxed-content-title">SOCIAL OUTREACH</h2> | ||
+ | <p>We held...</p> | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="col-md-6"> | ||
+ | <div class="boxed-content left-aligned left-boxed-icon"> | ||
+ | <i class="fa fa-cog"></i> | ||
+ | <h2 class="boxed-content-title">NEW APPLICATION</h2> | ||
+ | <p>Our design can be applied to ...</p> | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="col-md-6"> | ||
+ | <div class="boxed-content left-aligned left-boxed-icon"> | ||
+ | <i class="fa fa-users"></i> | ||
+ | <h2 class="boxed-content-title">EFFCTIVE COLLABORATION</h2> | ||
+ | <p>We have discussions with....</p> | ||
+ | </div> | ||
+ | </div> | ||
+ | </div> | ||
+ | </div> | ||
+ | </section> | ||
+ | <!-- END GOOD POINTS --> | ||
+ | <!-- DEMONSTRATION --> | ||
+ | <section> | ||
+ | <div class="container"> | ||
+ | <h2 class="section-heading sr-only">DEMONSTRATION</h2> | ||
+ | <div class="tab-content"> | ||
+ | <div class="tab-pane fade in active text-center" id="tab-bottom1"> | ||
+ | <img src="assets/img/hero-unit-obj.png" class="img-responsive center-block margin-bottom-30px" alt="Ultra Responsive"> | ||
+ | <h3 class="text-accent-color">DETECTION</h3> | ||
+ | <p class="lead">dCas9 sgRNA </p> | ||
+ | </div> | ||
+ | <div class="tab-pane fade text-center" id="tab-bottom2"> | ||
+ | <img src="assets/img/hero-unit-obj3.png" class="img-responsive center-block margin-bottom-30px" alt="Easy to Customize"> | ||
+ | <h3 class="text-accent-color">SIGNALING</h3> | ||
+ | <p class="lead">FLUC</p> | ||
+ | </div> | ||
+ | <div class="tab-pane fade text-center" id="tab-bottom3"> | ||
+ | <img src="assets/img/hero-unit-obj.png" class="img-responsive center-block margin-bottom-30px" alt="Clean and Elegant Design"> | ||
+ | <h3 class="text-accent-color">ANALYSIS</h3> | ||
+ | <p class="lead"> DATA</p> | ||
+ | </div> | ||
+ | <div class="tab-pane fade text-center" id="tab-bottom4"> | ||
+ | <img src="assets/img/free.png" class="img-responsive center-block margin-bottom-30px" alt="Free Updates and Support"> | ||
+ | <h3 class="text-accent-color">TREATMENT</h3> | ||
+ | <p class="lead">treatment</p> | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="custom-tabs-line tabs-line-top"> | ||
+ | <ul class="nav" role="tablist"> | ||
+ | <li class="active"><a href="#tab-bottom1" role="tab" data-toggle="tab">DETECTION</a></li> | ||
+ | <li><a href="#tab-bottom2" role="tab" data-toggle="tab">SIGNALING</a></li> | ||
+ | <li><a href="#tab-bottom3" role="tab" data-toggle="tab">ANALYSIS</a></li> | ||
+ | <li><a href="#tab-bottom4" role="tab" data-toggle="tab">TREATMENT</a></li> | ||
+ | </ul> | ||
+ | </div> | ||
</div> | </div> | ||
− | + | </section> | |
− | </section> | + | <!-- END DEMONSTRATION --> |
− | <!-- | + | |
<!-- FOOTER --> | <!-- FOOTER --> | ||
<footer> | <footer> |
Revision as of 04:12, 13 August 2017
DESCRIPTION
Cancer is one of the most deadly diseases in the world. Cancer accounts for more than 8.8 million deaths in 2015. Lung cancer, one of the top five cancers, took away 1.69 million lives in 2015. Although medicine and cancer treatments have been highly developed overtime, it is still difficult to diagnose and cure lung cancer in its early stage, particularly for non-small cell lung cancer (NSCLC).
Our main task is to construct a test paper that contains a powerful biosensor capable of detecting any DNA sequence. The biosensor, which is composed by dcas9 and T7 polymerase coupled system, can act like a smart automatic switch. When the test paper detects a particular DNA sequence, it then releases a visible signal. For diagnosing NSCLC cancer, we will use our biosensor to detect the fusion gene EML4-ALK, which is thought to have huge connections with lung cancer. The formation of this protein has to do with the alteration that occurred in the chromosomes. The alteration means one small piece of chromosome mysteriously going to the tail of another chromosome. If we are able to use our dcas9 and T7 polymerase coupled system to find EML4-ALK effectively and identify it at an early stage, then we will be creating a faster and safer cancer diagnostic process and immensely help people in pain with NSCLC cancer or even other types of cancers.
DEMONSTRATION
DETECTION
dCas9 sgRNA
SIGNALING
FLUC
ANALYSIS
DATA
TREATMENT
treatment