Difference between revisions of "Team:NAU-CHINA"

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<p>Fusarium head blight（FHB）is one of the most destructive global disease of cereal，which poses a significant threat to the wheat production and the safety of food. Fusarium Graminearum predominates among several Fusarium species that can cause FHB. Deoxynivalenol (DON) and zearalenone (ZEN) compounds, produced by Fusarium that are common contaminants which pose a threat to human and animal health .So the main purpose of our project is to treat FHB thoroughly，not only kill the F. graminearum，but also degrade DON and ZEN. We choose to engineer Yeast-based biosensor and bio-defender. Considering biosafety，our project also includes a kill switch-- a self-destruction system ,which is responsible for preventing gene contamination. The mammalian Bax protein will confer a lethal phenotype when expressed in yeast. This reassures that the yeast removes itself when the threat of F. graminearum is gone.</p>
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<p>Fusarium head blight（FHB）is one of the most destructive global disease of cereal，which poses a significant threat to the wheat production and the safety of food. Fusarium Graminearum predominates among several Fusarium species that can cause FHB. Deoxynivalenol (DON) and zearalenone (ZEN) compounds, produced by Fusarium that are common contaminants which pose a threat to human and animal health .So the main purpose of our project is to treat FHB thoroughly，not only kill the <i>F. graminearum</i>，but also degrade DON and ZEN. We choose to engineer Yeast-based biosensor and bio-defender. Considering biosafety，our project also includes a kill switch-- a self-destruction system ,which is responsible for preventing gene contamination. The mammalian Bax protein will confer a lethal phenotype when expressed in yeast. This reassures that the yeast removes itself when the threat of <i>F. graminearum</i> is gone.</p>
  
 
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Revision as of 06:48, 21 June 2017

Description

Fusarium head blight（FHB）is one of the most destructive global disease of cereal，which poses a significant threat to the wheat production and the safety of food. Fusarium Graminearum predominates among several Fusarium species that can cause FHB. Deoxynivalenol (DON) and zearalenone (ZEN) compounds, produced by Fusarium that are common contaminants which pose a threat to human and animal health .So the main purpose of our project is to treat FHB thoroughly，not only kill the F. graminearum，but also degrade DON and ZEN. We choose to engineer Yeast-based biosensor and bio-defender. Considering biosafety，our project also includes a kill switch-- a self-destruction system ,which is responsible for preventing gene contamination. The mammalian Bax protein will confer a lethal phenotype when expressed in yeast. This reassures that the yeast removes itself when the threat of F. graminearum is gone.