Difference between revisions of "Template:TU Darmstadt/Flowchart"

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             id="tspan1724">1. Chitosan:</tspan><tspan
 
             id="tspan1724">1. Chitosan:</tspan><tspan
 
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             id="tspan1846">antimicrobial properties and supports scar free wound healing.</tspan></text>
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             id="tspan1846">antimicrobial properties and supports scar free wound healing.</tspan><tspan
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            id="tspan1151"><a href="https://2017.igem.org/Team:TU_Darmstadt/project#two">Visit the subpage!</a></tspan></text>
 
         <text
 
         <text
 
           xml:space="preserve"
 
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             id="tspan3405">2. Wound infection:</tspan><tspan
 
             id="tspan3405">2. Wound infection:</tspan><tspan
 
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             id="tspan4655">3. Chitin Synthase:</tspan><tspan
 
             id="tspan4655">3. Chitin Synthase:</tspan><tspan
 
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             style="font-size:4.23333311px;line-height:0.5em;stroke-width:0.26458332"
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             id="tspan4665">tetrameric and pentameric chitin.</tspan><a href="https://2017.igem.org/Team:TU_Darmstadt/project/chitin_synthase"><tspan
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             id="tspan4665">tetrameric and pentameric chitin.</tspan><tspan
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            id="tspan4753">Visit the subpage -&gt;</tspan></a></text>
+
              id="tspan4753"></tspan><tspan
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              id="tspan1145"><a
 +
            href="https://2017.igem.org/Team:TU_Darmstadt/project/chitin_synthase">Visit the subpage!</a></tspan></text>
 
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         <text
 
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             id="tspan5429">called chitin deacetylases. In our case,</tspan><tspan
 
             id="tspan5429">called chitin deacetylases. In our case,</tspan><tspan
 
             id="tspan6310"
 
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            style="font-size:4.23333311px;line-height:0.5em;stroke-width:0.26458332">we use NodB and COD.</tspan><a href="https://2017.igem.org/Team:TU_Darmstadt/project/chitin_deacetylase"><tspan
 
 
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             style="font-size:4.23333311px;line-height:0.5em;stroke-width:0.26458332">we use NodB and COD.</tspan><tspan
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            id="tspan5503">Visit the subpage -&gt;</tspan></a></text>
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              id="tspan1147"><a
 +
            href="https://2017.igem.org/Team:TU_Darmstadt/project/chitin_deacetylase">Visit the subpage!</a></tspan></text>
 
         <text
 
         <text
 
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             id="tspan6372">to a flourophor via a peptide linker. This makes it</tspan><tspan
 
             id="tspan6372">to a flourophor via a peptide linker. This makes it</tspan><tspan
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             style="font-size:4.23333311px;line-height:0.5em;stroke-width:0.26458332">possible to detect exoproteases from pathogenic</tspan><tspan
 
             style="font-size:4.23333311px;line-height:0.5em;stroke-width:0.26458332">possible to detect exoproteases from pathogenic</tspan><tspan
 
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             style="font-size:4.23333311px;line-height:0.5em;stroke-width:0.26458332"
−
             id="tspan6374">bacteria within minutes.</tspan><a href="https://2017.igem.org/Team:TU_Darmstadt/project/chemistry"><tspan
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             id="tspan6374">bacteria within minutes.</tspan><tspan
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            id="tspan6434">Visit the subpage -&gt;</tspan></a></text>
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              id="tspan6434"></tspan><tspan
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              id="tspan1149"><a
 +
            href="https://2017.igem.org/Team:TU_Darmstadt/project/chemistry">Visit the subpage!</a></tspan></text>
 
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Revision as of 13:15, 30 October 2017

image/svg+xml 1. Chitosan:Chitosan is a derivate of the linear polysaccharide chitin. The chemical and physical properties can vary remarkably. This enables a huge scope of applications. Chitosan shows antimicrobial properties and supports scar free wound healing.Visit the subpage! 2. Wound infection:Simple and cheap wound treatment is a challenging task.The detection of potentially present pathogenic bacteria iscomplicated, as removal of the wound dressing disrupts thehealing process. 3. Chitin Synthase:To realize the synthesis of chitosan, for usage in wounddressing hydrogels, we produce chitin out of N-acetyl-glucosamine-UDP monomers. Chitin is a precursor for chitosan.We implement the chitin synthase NodC, which createstetrameric and pentameric chitin.Visit the subpage! 4. Chitin Deacetylase:To manufacture chitosan out of chitin, the producedchitin oligomers have to be deacetylated. This can beperformed by using certain hydrolyzing enzymes called chitin deacetylases. In our case,we use NodB and COD.Visit the subpage! 5. Chemistry:To deal with the problem of wound infections andtheir detection, our synthesized chitosan is linkedto a flourophor via a peptide linker. This makes itpossible to detect exoproteases from pathogenicbacteria within minutes.Visit the subpage!