Difference between revisions of "Team:ASIJ TOKYO/Parts"

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<h2 class="major">Composite Parts</h2>
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<p>COX-2 promoter - FRB-Nluc398 </p>
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c-Myc promoter - FKBP-Cluc394
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Promoter - RBS - COX-2 gene
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Promoter - RBS - c-Myc gene
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Revision as of 09:35, 31 October 2017

Basic Parts

Basic parts are defined as "functional unit[s] of DNA that cannot be subdivided into smaller component parts."

Basic Parts

BBa_K2226003 - COX-2 gene

This part consists of the gene for cyclooxygenase-2 (COX-2), an enzyme that is found in elevated levels during inflammation, predominantly found in gastric mucosa and kidneys.

BBa_K2226004 - c-Myc gene

This part consists of the mutated c-Myc gene, which is a regulator gene that codes for a transcription factor. The expressed protein controls multiple functions including cell cycle progression, apoptosis, and cellular transformation. The mutated version of c-Myc is expressed constitutively in many cancers.

BBa_K2226001 - COX-2 promoter and BBa_K2226002 - c-Myc promoter

These parts promote the transcription of the COX-2 gene while binding to reporter system FkBP-Cluc394, and regulate transcription of the c-Myc gene while binding to reporter system FRB-Nluc398, respectively.

Composite Parts

Composite parts are defined as "functional unit[s] of DNA consisting of two or more basic parts assembled together."

Composite Parts

BBa_K2226000

COX-2 promoter - FRB-Nluc398

BBa_K2226005

c-Myc promoter - FKBP-Cluc394

BBa_K2226006

Promoter - RBS - COX-2 gene

BBa_K2226007

Promoter - RBS - c-Myc gene