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Revision as of 14:25, 29 June 2017
Croc'n Cholera
Home
What is cholera ?
The culprit :
Vibrio cholerae
Vibrio cholerae
Contaminates water and affects people in developing countries, war zones and natural disaster zones
2011
Last epidemy in an occidental country
4 millions
Number of cases per year
42
Number of concerned countries
→ Implemented solutions and their problems :
Too complicated to measure out
Too complicated to set up for big volumes
Too expensive
Our solution :
A synthetic biology innovative approach !
Fight V. cholerae with crocodile antimicrobial peptides !
What is our project ?
Our savior :
Sobki the crocodile
Sobki the crocodile
Can produce antimicrobial peptides that enables him to destroy V. cholerae in his natural habitat
Our system is made of two engineered microorganisms: Vibrio harveyi to detect V. cholerae and Pichia pastoris to produce crocodile AMPs. Thus one of our biggest challenge is to create an eukaryote-prokaryote communication system.
