Difference between revisions of "Team:NUDT CHINA"

NUDT_CHINA

MicroRNAs (miRNAs) have been proven to play important roles

on post-transcriptionalregulation of the gene expression by

direct base pairing to target sites within untranslated regions of

messenger RNAs.

However, the functions of most microRNAs remain to be

discovered. Our project attempts to develop a novel sponge for

miRNAs, which would knock down the abundance of target

miRNA in the cells.

Thus the sponge will be a miRNA inhibitor to be used to induce

miRNA loss-of-function phenotypes or other further applications

like small non-coding RNA-based diagnostic and therapeutic applications.