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Revision as of 00:20, 21 October 2017
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Our Story
NUDT_CHINA
MicroRNAs (miRNAs) have been proven to play important roles on post-transcriptionalregulation of the gene expression by direct base pairing to target sites within untranslated regions of messenger RNAs.
However, the functions of most microRNAs remain to be discovered. Our project attempts to develop a novel sponge for miRNAs, which would knock down the abundance of target miRNA in the cells.
Thus the sponge will be a miRNA inhibitor to be used to induce miRNA loss-of-function phenotypes or other further applications like small non-coding RNA-based diagnostic and therapeutic applications.
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