Difference between revisions of "Team:Newcastle/Results"

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           <h2 style="font-family: Rubik; text-align: left; margin-top: 1%"> Rationale and Aim </h2>
 
           <h2 style="font-family: Rubik; text-align: left; margin-top: 1%"> Rationale and Aim </h2>
           <p>The Sensynova multicellular biosensor platform has been developed to overcome the limitations identified by our team [hyperlink to human practices] that hamper the success in biosensors development. One of these limits regards the lack of modularity and reusability of the various components. Our platform design, based on the expression of three main modules (Detector, Processor and Output) by three E.coli strains in co-culture, allows the switch of possible variances for each module and the production of multiple customised biosensors.
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           <p>The Sensynova multicellular biosensor platform has been developed to overcome the limitations identified by our team [hyperlink to human practices] that hamper the success in biosensors development. One of these limits regards the lack of modularity and reusability of the various components. Our platform design, based on the expression of three main modules (Detector, Processor and Output) by three <i>E.coli </i> strains in co-culture, allows the switch of possible variances for each module and the production of multiple customised biosensors.
 
           </br></br>
 
           </br></br>
 
           This section of the project is based on testing the modularity of the system by implementing the biosensor created by the 2017 Evry Paris-Saclay iGEM team into the Sensynova platform as part of our collaboration requirement.</p>
 
           This section of the project is based on testing the modularity of the system by implementing the biosensor created by the 2017 Evry Paris-Saclay iGEM team into the Sensynova platform as part of our collaboration requirement.</p>
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           <img src="https://static.igem.org/mediawiki/2017/1/1b/T--Newcastle--Lais--Evry--Biosensor.png" class="img-fluid border border-dark rounded" style="margin: 2%">
 
           <img src="https://static.igem.org/mediawiki/2017/1/1b/T--Newcastle--Lais--Evry--Biosensor.png" class="img-fluid border border-dark rounded" style="margin: 2%">
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<p>
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<b>Figure 1:</b> <!--- Insert image name between tags. ---->
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<i> <b> Such and such </i> </b> <!--- Described what the diagram is showing. If biobricks are depicted give BBa_ numbers -->
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</p> </br>
 
            
 
            
 
           <p>The inducible system works as detailed in the diagram below. When pTAC is induced due to the presence of IPTG, PsiR is transcribed and binds to the pPsitac promoter repressing the transcription of the mCherry protein. When psicose is present, the sugar binds to PsiR, freeing up the promoter and subsequently the colour output</p>
 
           <p>The inducible system works as detailed in the diagram below. When pTAC is induced due to the presence of IPTG, PsiR is transcribed and binds to the pPsitac promoter repressing the transcription of the mCherry protein. When psicose is present, the sugar binds to PsiR, freeing up the promoter and subsequently the colour output</p>

Revision as of 20:35, 27 October 2017

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Our Experimental Results

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