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<div class="left-step"> | <div class="left-step"> | ||
<div class="step">1. 1.</div> | <div class="step">1. 1.</div> | ||
− | <div class="title"> | + | <div class="title">Plasmid Groups</div> |
− | <p> | + | <p>Multi-plasmid framework would not be much without multiple plasmids. The synthetic origin of replication allows to co-maintain different unique plasmid groups in a single cell.</p> |
− | + | ||
</div> | </div> | ||
<div class="left-step"> | <div class="left-step"> | ||
<div class="step">1. 2.</div> | <div class="step">1. 2.</div> | ||
− | <div class="title"> | + | <div class="title">Copy Number Control</div> |
− | <p> | + | <p>With the SynORI system you can adjust your plasmids' copy number in constitutive and inducible manner or virtually any signal pattern.</p> |
− | + | ||
</div> | </div> | ||
<div class="left-step"> | <div class="left-step"> | ||
<div class="step">1. 3.</div> | <div class="step">1. 3.</div> | ||
− | <div class="title"> | + | <div class="title">Adjusting Copy Number</div> |
− | <p> | + | <p>With the SynORI we introduce the world’s first inducible precise copy number plasmids. You may choose any particular plasmid to be low or high copy number.</p> |
− | + | ||
</div> | </div> | ||
<div class="left-step"> | <div class="left-step"> | ||
<div class="step">1. 4.</div> | <div class="step">1. 4.</div> | ||
− | <div class="title"> | + | <div class="title">Rop </div> |
<p>Would you like to globally control your plasmid groups’ copy number, we have optimized the effects of Rop protein. By inducing the expression of Rop you can lower the copy number of all plasmid groups universally. </p> | <p>Would you like to globally control your plasmid groups’ copy number, we have optimized the effects of Rop protein. By inducing the expression of Rop you can lower the copy number of all plasmid groups universally. </p> | ||
</div> | </div> | ||
<div class="left-step"> | <div class="left-step"> | ||
<div class="step">1. 5.</div> | <div class="step">1. 5.</div> | ||
− | <div class="title"> | + | <div class="title">Selection System</div> |
− | <p> | + | <p>Five different plasmids equals to five different antibiotics for external selection? Not anymore. SynORI contains a five-part self-assembling selection system which uses only one antibiotic resistance gene.</p> |
− | + | ||
</div> | </div> | ||
<div class="left-step"> | <div class="left-step"> | ||
<div class="step">1. 6.</div> | <div class="step">1. 6.</div> | ||
− | <div class="title">Segregation | + | <div class="title">Segregation System</div> |
− | <p> | + | <p>You might want to use our active partitioning device for your lower-than-30 copy number plasmids. The device ensures stable specific low copy number plasmid group inheritance.</p> |
− | + | ||
</div> | </div> | ||
<div class="left-step"> | <div class="left-step"> |
Revision as of 00:21, 1 November 2017
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Our Solution: the SynORI Framework
Multi-plasmid framework would not be much without multiple plasmids. The synthetic origin of replication allows to co-maintain different unique plasmid groups in a single cell.
With the SynORI system you can adjust your plasmids' copy number in constitutive and inducible manner or virtually any signal pattern.
With the SynORI we introduce the world’s first inducible precise copy number plasmids. You may choose any particular plasmid to be low or high copy number.
Would you like to globally control your plasmid groups’ copy number, we have optimized the effects of Rop protein. By inducing the expression of Rop you can lower the copy number of all plasmid groups universally.
Five different plasmids equals to five different antibiotics for external selection? Not anymore. SynORI contains a five-part self-assembling selection system which uses only one antibiotic resistance gene.
You might want to use our active partitioning device for your lower-than-30 copy number plasmids. The device ensures stable specific low copy number plasmid group inheritance.
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A framework for multi-plasmid sytems
It is time to make the work with plasmid systems more precise, convenient and extend its possibilities.
Your personal SynORI system is now ready. It is as simple as that.
Explore synori system in detailPlease select plasmid number that will appear in a cell.
Preview of Rop induction
Choose level of ROP induction
Do you want to add ROP protein to your SynORI system?
This might be helpful:
If your copy number is lower than 30, we recommend checking the box.