Difference between revisions of "Template:Heidelberg/best basic"
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| − | {{Heidelberg/partspanelleft|{{#tag:html|<a href=" | + | {{Heidelberg/partspanelleft|{{#tag:html|<a href="http://parts.igem.org/Part:BBa_K2398000">BBa_K2398000</a>}}|We present as best basic part the codon-optimized version of the cytochrome c protein that is able to convert silicon educts to organosilicon products.|https://static.igem.org/mediawiki/2017/1/1d/T--Heidelberg--CytochromeCRMA.png}} |
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This cytochrome c variant provides an easy to use tool that is accessible to everyone in the synthetic biology community and allows the user to harness the vast potential of organosilicons. | This cytochrome c variant provides an easy to use tool that is accessible to everyone in the synthetic biology community and allows the user to harness the vast potential of organosilicons. | ||
This basic part exhibits a strong tendency to form silicon-carbon bonds and is, therefore, a valuable addition to perform controlled organic chemistry in microorganisms. | This basic part exhibits a strong tendency to form silicon-carbon bonds and is, therefore, a valuable addition to perform controlled organic chemistry in microorganisms. | ||
A triple mutant of this part has already been applied in the successful synthesis of organosilicons as a proof-of-concept. | A triple mutant of this part has already been applied in the successful synthesis of organosilicons as a proof-of-concept. | ||
| − | As a next step, this part can be implemented in the directed evolution approach of phage-assisted continuous evolution (PACE) or in the phage-related discontinuous evolution (PREDCEL) approach to improve organosilicon synthesis by cytochrome engineering.| | + | As a next step, this part can be implemented in the directed evolution approach of phage-assisted continuous evolution (PACE) or in the phage-related discontinuous evolution (PREDCEL) approach to improve organosilicon synthesis by cytochrome engineering.| |
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Revision as of 16:29, 1 November 2017
BBa_K2398000
We present as best basic part the codon-optimized version of the cytochrome c protein that is able to convert silicon educts to organosilicon products.
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