Difference between revisions of "Team:UNBC-Canada"

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<h1> Project Description </h1>
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                            <h1>UNBC-Canada Home</h1>
<h3>Our Project Thus Far</h3>
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<p> Our project will attempt to encompass the two largest issues that face healthcare as a result of Methicillin-Resistant Staphylococcus aureus (MRSA): detection and treatment. We will attempt to develop a rapid, bedside detection mechanism specific for MRSA, as well as a novel approach to treating infectious disease involving gene silencing, with applications directed at MRSA.
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For context, the proposed detection mechanism will work analogous to a pregnancy test. We will develop a chromogenic assay that will produce a visible colour change in the presence of our target MRSA-specific antigen. This assay will include an antibody against an antigen specific to S. aureus, which will be conjugated to an enzyme. Upon binding of the antibody to the target antigen, substrate will then be introduced to the strip; the conversion of substrate to product via the enzyme will give the desired colour change. Traditionally, similar tests operate on the time scale of 5-10 minutes, which is what we are hoping to achieve. Specific details have yet to be finalized.
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Furthermore, we will be using post-transcriptional gene silencing to treat cultures of MRSA, with preliminary work in Staphylococcus epidermidis, as it is safer to work with. Currently, we plan to target the following genes: </p>
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<ul>
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<li> mecA – codes for Penicillin Binding Protein, a key contributer to methicillin resistance </li>
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<li> secA – codes for an essential ATPase of the bacterial secretion system, which is responsible for virulence </li>
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<li> blaZ & blaR1 – antibiotic-sensing and metabolising genes</li>
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<li> glmM – codes for a phosphoglucosamine mutase, necessary for peptidoglycan synthetsis </li>
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<p> Initial experiments will involve transforming a plasmid carrying a gene that will code for an sRNA that will bind to the ribosome binding site (RBS) of the target mRNA and measuring gene silencing efficiency. After confirming the efficacy of gene silencing, we will investigate phage delivery as an avenue of pursuit. </p>
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<h5>Before you start: </h5>
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<p> Please read the following pages:</p>
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<li>  <a href="https://2017.igem.org/Competition">Competition Hub</a> </li>
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<li> <a href="https://2017.igem.org/Competition/Deliverables/Wiki">Wiki Requirements page</a></li>
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<li> <a href="https://2017.igem.org/Resources/Template_Documentation">Template documentation</a></li>
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<h5> Styling your wiki </h5>
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<p>You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.</p>
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<p>While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.</p>
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<h5> Wiki template information </h5>
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<p>We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the <a href="https://2017.igem.org/Judging/Pages_for_Awards">Pages for awards</a> link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!</p>
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<h5> Editing your wiki </h5>
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<p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p>
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<p> <a href="https://2017.igem.org/wiki/index.php?title=Team:Example&action=edit"> </a>Use WikiTools - Edit in the black menu bar to edit this page</p>
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<h5>Tips</h5>
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<p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
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<li>State your accomplishments! Tell people what you have achieved from the start. </li>
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<li>Be clear about what you are doing and how you plan to do this.</li>
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<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
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<li>Make sure information is easy to find; nothing should be more than 3 clicks away.  </li>
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<li>Avoid using very small fonts and low contrast colors; information should be easy to read.  </li>
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<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="https://2017.igem.org/Calendar">iGEM 2017 calendar</a> </li>
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<li>Have lots of fun! </li>
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<h5>Inspiration</h5>
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<p> You can also view other team wikis for inspiration! Here are some examples:</p>
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<ul>
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<li> <a href="https://2014.igem.org/Team:SDU-Denmark/"> 2014 SDU Denmark </a> </li>
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<li> <a href="https://2014.igem.org/Team:Aalto-Helsinki">2014 Aalto-Helsinki</a> </li>
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<li> <a href="https://2014.igem.org/Team:LMU-Munich">2014 LMU-Munich</a> </li>
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<li> <a href="https://2014.igem.org/Team:Michigan"> 2014 Michigan</a></li>
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<li> <a href="https://2014.igem.org/Team:ITESM-Guadalajara">2014 ITESM-Guadalajara </a></li>
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<li> <a href="https://2014.igem.org/Team:SCU-China"> 2014 SCU-China </a></li>
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<h5> Uploading pictures and files </h5>
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<p> You can upload your pictures and files to the iGEM 2017 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name. <br />
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When you upload, set the "Destination Filename" to <br><code>T--YourOfficialTeamName--NameOfFile.jpg</code>. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)<br><br>
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<a href="https://2017.igem.org/Special:Upload">
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UPLOAD FILES
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                        <h1>Single Blog</h1>
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                        <p>Everything created in simple way</p>
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                <h1>Pain of itself,but because and occasionally circumstances occur those who do not know how to pursue pleasure rationally encounter</h1>
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                              <span class="post-single-date">14 Jun - 2015</span>
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                                    <span class="title">Brendan Reiter</span>
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                                    <span class="info">Director of Project and Wiki Design and Wet Lab Operations</span>
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                                  <span class="info-title">Tags:</span>  
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                                      <li><a href="#">clean</a></li>
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                                      <li><a href="#">modern</a></li>
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                                      <li><a href="#">beauty</a></li>
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                                      <li><a href="#">fashion</a></li>
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                    <p>Hello fellow iGEMmers! I am in my fifth and final year of an honours biochemistry and molecular biology degree with a chemistry minor, and this is my second year participating in iGEM with UNBC's second ever iGEM team. Outside of the iGEM lab, you can find me investigating the anti-cancer properties of wild mushrooms from Northern BC. I enjoy bodybuilding, volleyball, basketball, and am an avid coffee connoisseur. I can lay down a mean drum solo and will laugh longer than appropriate at a dad joke.</p>
 
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                  <p>Desires to obtain pain of itself, because it is pain, but because occasionally circumstances occur in which toil and pain can procure him some great pleasure. To take a trivial example, which of us ever undertakes laborious physical exercise, except to obtain some advantage from it.who do not know how to pursue pleasure rationally encounter consequences that are extremely painful. Nor again is there anyone who loves or pursues or desires to obtain pain advantage.
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                    The master-builder of human happiness. No one rejects, dislikes, or avoids pleasure itself, because it is pleasure, but because those who do not know how to pursue pleasure rationally encounter consequences that are extremely painful. Nor again is there anyone who loves or pursues or desires to obtain pain of itself, because it is pain, but because occasionally circumstances occur in which toil and pain can procure him some great pleasure. To take a trivial example, which of us ever undertakes laborious physical exercise, except to obtain some great explorer of the truth, the master-builder of human happiness. No one rejects, dislikes, or avoids pleasure itself, because it is pleasure, but because those who do not know how to pursue pleasure rationally encounter consequences that are extremely painful. Nor again is there.</p>
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                     <blockquote>Mistaken idea of denouncing pleasure and praising pain was born and I will give you a complete account of the system, and expound the actual teachings of the great explorer of the truth, the master-builder of human happiness.who do not know how to pursue pleasure rationally encounter consequences that are extremely painful. Expound the actual teachings of the great explorer of the truth, account of the system the master-builder of human happiness.</blockquote>
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                                    <span class="title">Keanna Woidak</span>
 
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                                    <span class="info">Director of Human Practices and Public Outreach</span>
                  <p><b>Avoids pleasure itself, because it is pleasure,</b> but because those who do not know how to pursue pleasure rationally encounter consequences that are extremely painful. Nor again is there anyone who loves or pursues or desires to obtain pain of itself, because it is pain, but because occasionally circumstances occur in which toil and pain can procure him some great pleasure. To take a trivial example, which of us ever undertakes laborious physical exercise, except to obtain some.
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                    Totam rem aperiam, eaque ipsa quae ab illo inventore veritatis et quasi architecto beatae vitae dicta sunt explicabo. Nemo enim ipsam voluptatem quia voluptas sit aspernatur aut odit aut fugit, sed quia undertakes laborious physical exercise, except
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                    Totam rem aperiam, eaque ipsa quae ab illo inventore veritatis et quasi architecto beatae vitae dicta sunt explicabo consequuntur magni dolores eos qui ratione voluptatem sequi nesciunt. Neque porro quisquam est, qui dolorem ipsum quia. great explorer of the truth, the master-builder of human happiness. No one rejects, dislikes, or avoids pleasure itself, because it is pleasure, but because those who do not know how to pursue pleasure rationally encounter consequences that extremely.</p>
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<p>Hello! I am in my last year of my Biomedical Studies degree. This is my second year being apart of iGEM! Beyond iGEM and the lab, I enjoy experiencing food and the flavors of the world, and admit to having an extreme sweet tooth. To balance my love for food, I spend much of my spare time exercising being an avid and a passionate long-distance runner.</p>
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                                    <span class="title">Connor Johnson</span>
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<p> I am in my third year of a Biochemistry and molecular biology degree. I joined this project because I have personally seen how MRSA affects friends and rural communities. My hope is to contribute to the global effort to develop more effective treatment options against multi drug resistant bacterial species.</p>
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                                    <span class="title">Katelynn Rozmarniewich</span>
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<p>I am in my final year of BSc BCMB. Previously, I attended college for Integrated Science and Registered Nursing. I am pursuing a MSc in Biochemistry and MD in Northern BC. My main interest is in the detection, treatment and global impacts of Cervical Cancer. Outside my passion for Health, I hold a strong fervidness to challenging myself through travel. These are ways I better my understanding of our planet and ourselves while staying cultivated.</p>
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                                    <span class="title">Lon Kerr</span>
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<p>Lon Kerr is one of the founding members of UNBC’s iGEM team. Lon’s primary interests are in biochemistry and molecular biology but throughout his undergrad he has found the opportunity to indulge side projects in analytical chemistry. If Lon could do anything he would fly kites. His dream activity is flying his 10m power kite over the waves any lake that will welcome him. Through working with others Lon believes that anything is possible and that there is no challenge too ominous to handle!</p>
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                                    <span class="title">Jason Chu</span>
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<p>I am currently in my fourth year studying Biochemistry. I love science and it has been a blast working with this awesome team. Some of my other interests include listening to and playing music, all sports, and eating fantasies food!</p>
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                                    <span class="title">Jared Pritchard</span>
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<p>Hey I’m Jared a 3rd year bio-medical student, outside of school I’m interested in food, house music, and beach volleyball. My favorite condiment is hot sauce, favorite desert is chocolate cake and favorite meal is probably pizza with hot sauce. In my spare time you are most likely to find me eating and listening to music.</p>
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                                    <span class="title">Michael Simmons</span>
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<p>I am an international student from the Bahamas, majoring in Biochemistry. I've joined our iGEM team because I am very interested in genetic modification and it's limits in helping a wide array of issues within our world today. Music and travelling excite me, especially when I'm able to learn and new language and culture</p>
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                                    <span class="title">Raliat Abioye</span>
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<p>Hey guys! I am in my third year of Biochemistry and Molecular Biology. I am originally from Brampton, Ontario where I lived for 15 years. An interesting fact about me is that I was born in London, England and I would love to move back in the future. I chose to be a part of the UNBC iGEM team because I was excited to see the great innovations students can come up with with just a little bit of creativity and inspiration for solving world issues. I am excited and very proud to be a part of such an amazing team filled with various different personalities and experience levels meshing together to achieve a common goal.</p>
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                                    <span class="title">Aashka Jani</span>
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<p>I’m currently in my fourth year of a double major in Biochemistry & Molecular Biology and Psychology. My career goal is to one day obtain a medical degree and become a practicing physician. I was born in Chicago but have lived in Prince George for the past 17 years. One of the things I love about Northern BC is that it is continually emerging with new opportunities.</p>
 
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Revision as of 03:28, 2 November 2017

UNBC-Canada Home

Team
Brendan Reiter Director of Project and Wiki Design and Wet Lab Operations

Hello fellow iGEMmers! I am in my fifth and final year of an honours biochemistry and molecular biology degree with a chemistry minor, and this is my second year participating in iGEM with UNBC's second ever iGEM team. Outside of the iGEM lab, you can find me investigating the anti-cancer properties of wild mushrooms from Northern BC. I enjoy bodybuilding, volleyball, basketball, and am an avid coffee connoisseur. I can lay down a mean drum solo and will laugh longer than appropriate at a dad joke.

Keanna Woidak Director of Human Practices and Public Outreach

Hello! I am in my last year of my Biomedical Studies degree. This is my second year being apart of iGEM! Beyond iGEM and the lab, I enjoy experiencing food and the flavors of the world, and admit to having an extreme sweet tooth. To balance my love for food, I spend much of my spare time exercising being an avid and a passionate long-distance runner.

Connor Johnson Student Member

I am in my third year of a Biochemistry and molecular biology degree. I joined this project because I have personally seen how MRSA affects friends and rural communities. My hope is to contribute to the global effort to develop more effective treatment options against multi drug resistant bacterial species.

Katelynn Rozmarniewich Student Member

I am in my final year of BSc BCMB. Previously, I attended college for Integrated Science and Registered Nursing. I am pursuing a MSc in Biochemistry and MD in Northern BC. My main interest is in the detection, treatment and global impacts of Cervical Cancer. Outside my passion for Health, I hold a strong fervidness to challenging myself through travel. These are ways I better my understanding of our planet and ourselves while staying cultivated.

Lon Kerr Student Member and ex-Student Leader

Lon Kerr is one of the founding members of UNBC’s iGEM team. Lon’s primary interests are in biochemistry and molecular biology but throughout his undergrad he has found the opportunity to indulge side projects in analytical chemistry. If Lon could do anything he would fly kites. His dream activity is flying his 10m power kite over the waves any lake that will welcome him. Through working with others Lon believes that anything is possible and that there is no challenge too ominous to handle!

Jason Chu Student Member

I am currently in my fourth year studying Biochemistry. I love science and it has been a blast working with this awesome team. Some of my other interests include listening to and playing music, all sports, and eating fantasies food!

Jared Pritchard Student Member

Hey I’m Jared a 3rd year bio-medical student, outside of school I’m interested in food, house music, and beach volleyball. My favorite condiment is hot sauce, favorite desert is chocolate cake and favorite meal is probably pizza with hot sauce. In my spare time you are most likely to find me eating and listening to music.

Michael Simmons Student Member

I am an international student from the Bahamas, majoring in Biochemistry. I've joined our iGEM team because I am very interested in genetic modification and it's limits in helping a wide array of issues within our world today. Music and travelling excite me, especially when I'm able to learn and new language and culture

Raliat Abioye Student Member

Hey guys! I am in my third year of Biochemistry and Molecular Biology. I am originally from Brampton, Ontario where I lived for 15 years. An interesting fact about me is that I was born in London, England and I would love to move back in the future. I chose to be a part of the UNBC iGEM team because I was excited to see the great innovations students can come up with with just a little bit of creativity and inspiration for solving world issues. I am excited and very proud to be a part of such an amazing team filled with various different personalities and experience levels meshing together to achieve a common goal.

Aashka Jani Student Member

I’m currently in my fourth year of a double major in Biochemistry & Molecular Biology and Psychology. My career goal is to one day obtain a medical degree and become a practicing physician. I was born in Chicago but have lived in Prince George for the past 17 years. One of the things I love about Northern BC is that it is continually emerging with new opportunities.