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Revision as of 10:15, 1 August 2017

Croc'n Cholera
Home

We are iGEM INSA-UPS_France, a French team composed of students from Toulouse and Lyon. Our project is about crocodiles and cholera...
Scroll to know more about it!

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What
 
is
 
cholera?

The responsible:
Vibrio cholerae
Contaminates water and affects people in developing countries, war zones and natural disaster zones
2011
Last epidemy in an occidental country
4 millions
Number of cases per year
42
Number of concerned countries
→ Implemented solutions and their problems:
Too complicated to measure out
Too complicated to set up for big volumes
Too expensive

Our solution:
A synthetic biology innovative approach!

Fight V. cholerae with crocodile antimicrobial peptides!

What
 
is
 
our
 
project?
Our hero:
Sobki the crocodile
Can produce antimicrobial peptides that enables him to destroy V. cholerae in his natural habitat

Our system is made of two engineered microorganisms: Vibrio harveyi to detect V. cholerae and Pichia pastoris to produce crocodile AMPs. Thus one of our biggest challenge is to create an eukaryote-prokaryote communication system.